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Dietary supplement

Chiroin Ingredients & Drug Interactions

by Health Concerns

Chiroin label
See full label image
Tablet Or Pill Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Chiroin against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Chiroin is a dietary supplement by Health Concerns with 1 active ingredient. Its ingredients are commonly taken for polycystic ovary syndrome (pcos), anxiety and panic, depression and mood.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are D-Chiro Inositol. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Chiroin by Health Concerns

Ask about any prescription or over-the-counter medication and we check it for interactions with Chiroin by Health Concerns — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Chiroin by Health Concerns

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “Proprietary Blend of Carob pod extract” is a proprietary blend — the label doesn't break down how much of each component you get.

Chiroin contains one active ingredient: D-chiro inositol, a naturally occurring compound related to B vitamins that plays a role in blood sugar regulation and insulin signaling. It also includes a proprietary blend of carob pod extract, though we can't break down the exact components of that blend.

The rest of the tablet is made up of inactive ingredients — microcrystalline cellulose, silicon dioxide, stearic acid, croscarmellose sodium, vegetable magnesium stearate, and cellulose — which are standard fillers and binders that help hold the tablet together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: D-Chiro Inositol supplement for metabolic and fertility support.
  • We looked for evidence on: Polycystic ovary syndrome (PCOS), Anxiety, Depression, Infertility, Metabolic syndrome, Diabetes — and 4 related terms.
  • The strongest evidence on file: Inositol is rated "Possibly Effective" for Polycystic ovary syndrome (PCOS) (Natural Medicines).
  • Also on file: Inositol is rated "Possibly Effective" for Metabolic syndrome.
  • Also on file: Inositol is rated "Possibly Ineffective" for Anxiety, Depression.

D-chiro inositol shows possibly effective evidence for polycystic ovary syndrome (PCOS) and metabolic syndrome. It's also rated possibly effective for preterm labor.

However, the evidence for anxiety, diabetic neuropathy, and depression is rated possibly ineffective, meaning clinical research hasn't found it helpful for those uses.

The evidence, ingredient by ingredient Inositol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

D-chiro inositol is generally well tolerated at typical doses, though some people report mild digestive side effects — mainly diarrhea, gas, and nausea. In one study combining inositol with omega-3 fatty acids, a small number of children reported cold and allergy symptoms.

For pregnancy, inositol is rated possibly safe, but the safety data isn't fully established, so use only under medical supervision if you're pregnant or planning to become pregnant. There isn't enough reliable information on safety in breastfeeding — talk with your doctor or pharmacist for personalized advice.

Side effects, ingredient by ingredient Inositol

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Inositol.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs — insulin or oral medications — talk with your pharmacist before adding Chiroin. Inositol can increase your risk of low blood sugar (hypoglycemia), and your doctor may need to adjust your dose.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Chiroin may be worth considering if you have PCOS or metabolic syndrome. If you take diabetes medication, you'll need to check with your pharmacist or doctor first because inositol can lower blood sugar.

Anyone with concerns about digestive side effects or those pregnant or breastfeeding should discuss this with their healthcare provider before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Chiroin, straight from the product label.

Brand Health Concerns
Net contents 60 Tablet(s)
Market status On market
Date entered into DSLD Apr 25, 2017
DSLD ID 72772
Product type Botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Chiroin by Health Concerns, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
60
IngredientAmount% DV
D-Chiro Inositol300 mg--
Proprietary Blend of Carob pod extract0 NP--

Other ingredients: Microcrystalline Cellulose, Silicon Dioxide, Stearic Acid, Croscarmellose Sodium, Vegetable Magnesium Stearate, Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Take one to four tablets daily with meals, or as recommended by a health professional.

Precautions

Notice: This product is not intended for use by pregnant women.

Brand IP Statement(s)

Energetic Formulas

Combining modern research and ancient wisdom

FDA Statement of Identity

D-Chiro Inositol Herbal Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Chiroin by Health Concerns label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Chiroin label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Chiroin by Health Concerns

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.

Proprietary Blend of Carob pod extract

0 NP per serving

Other (inactive) ingredients: Microcrystalline Cellulose, Silicon Dioxide, Stearic Acid, Croscarmellose Sodium, Vegetable Magnesium Stearate, Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Chiroin by Health Concerns Drug Interactions

Want to check YOUR meds against Chiroin?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

D-Chiro Inositol 86

Individual Drug Interactions

The ingredients in Chiroin interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Chiroin interact with drugs. Each result below shows which ingredient is responsible. D-Chiro Inositol

Each ingredient & the kinds of drugs it affects

For each ingredient in Chiroin with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

D-Chiro Inositol1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that inositol lowers blood glucose levels and glycated hemoglobin (HbA1c) levels in patients with diabetes.

Likelihood Possible Evidence A
D-Chiro Inositol full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Chiroin, from the product label.

Health Concerns

See all Health Concerns products
Name
Health Concerns
Street Address
8001 Capwell Drive
City
Oakland
State
CA
ZipCode
94621
Phone Number
(800) 233-9355
Web Address
www.healthconcerns.com/pro
Pharmacist Counseling Corner

Chiroin by Health Concerns: Common Questions

Does Chiroin by Health Concerns interact with any medications?
Yes. Based on its ingredients, Chiroin has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Chiroin contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help with my PCOS?
D-chiro inositol is rated possibly effective for PCOS based on clinical research. It's one option to discuss with your doctor, though it's not a cure and works best as part of an overall treatment plan.
What side effects should I watch for?
Most people tolerate it well. The most common side effects are mild digestive issues — diarrhea, gas, and nausea. These usually fade as your body adjusts.
Is it safe to take if I'm pregnant?
Inositol is rated possibly safe in pregnancy, but the safety data isn't complete. If you're pregnant or planning to conceive, use it only under medical supervision — talk with your doctor or pharmacist first.
Can I take this for depression or anxiety?
The evidence doesn't support using inositol for depression or anxiety — both are rated possibly ineffective. It's not likely to help with those conditions based on current research.
What's D-chiro inositol?
D-chiro inositol is a natural compound related to the B vitamins that helps your body regulate blood sugar and respond to insulin. Your body makes some naturally, and you also get it from foods like beans and whole grains.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Chiroin is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Chiroin label
Go deeper

The Full Monographs Behind Chiroin’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Inositol

Interacts with 86 drugs

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, mood, and metabolic concerns. The stronge...

Read the full Inositol monograph →
Sources

Sources & How We Checked

Chiroin's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Inositol 14 references
  1. Palatnik A, Frolov K, Fux M, Benjamin J. Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. J Clin Psychopharmacol 2001;21:335-9.. PubMed
  2. Allan SJ, Kavanagh GM, Herd RM, Savin JA. The effect of inositol supplements on the psoriasis of patients taking lithium: a randomized, placebo-controlled trial. Br J Dermatol 2004;150:966-9. PubMed
  3. Machado-Vieira R, Viale CI, Kapczinski F. Mania associated with an energy drink: the possible role of caffeine, taurine, and inositol. Can J Psychiatry 2001;46:454-5. PubMed
  4. Kamenov Z, Kolarov G, Gateva A, Carlomagno G, Genazzani AD. Ovulation induction with myo-inositol alone and in combination with clomiphene citrate in polycystic ovarian syndrome patients with insulin resistance. Gynecol Endocrinol 2015;31(2):131-5. PubMed
  5. Matarrelli B, Vitacolonna E, D'Angelo M, et al. Effect of dietary myo-inositol supplementation in pregnancy on the incidence of maternal gestational diabetes mellitus and fetal outcomes: a randomized controlled trial. J Matern Fetal Neonatal Med 2013;26(1 PubMed
  6. Mukai T, Kishi T, Matsuda Y, Iwata N. A meta-analysis of inositol for depression and anxiety disorders. Hum Psychopharmacol 2014;29(1):55-63. PubMed
  7. Farren M, Daly N, McKeating A, Kinsley B, Turner MJ, Daly S. The Prevention of Gestational Diabetes Mellitus With Antenatal Oral Inositol Supplementation: A Randomized Controlled Trial. Diabetes Care. 2017;40(6):759-63. PubMed
  8. Zheng X, Liu Z, Zhang Y, et al. Relationship Between Myo-Inositol Supplementary and Gestational Diabetes Mellitus: A Meta-Analysis. Medicine (Baltimore). 2015;94(42):e1604. PubMed
  9. Crawford TJ, Crowther CA, Alsweiler J, Brown J. Antenatal dietary supplementation with myo-inositol in women during pregnancy for preventing gestational diabetes. Cochrane Database Syst Rev. 2015;(12):CD011507. PubMed
  10. Maurizi AR, Menduni M, Del Toro R, et al. A pilot study of D-chiro-inositol plus folic acid in overweight patients with type 1 diabetes. Acta Diabetol. 2017;54(4):361-65. PubMed
  11. Leppink EW, Redden SA, Grant JE. A double-blind, placebo-controlled study of inositol in trichotillomania. Int Clin Psychopharmacol. 2017;32(2):107-14. PubMed
  12. Lam S, Mandrekar SJ, Gesthalter Y. A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia. Cancer Prev Res (Phila). 2016;9(12):906-14.
  13. Wozniak J, Faraone SV, Chan J, et al. A randomized clinical trial of high eicosapentaenoic acid omega-3 fatty acids and inositol as monotherapy and in combination in the treatment of pediatric bipolar spectrum disorders: a pilot study. J Clin Psychiatry. PubMed
  14. Vitale SG, Corrado F, Caruso S, et al. Myo-inositol supplementation to prevent gestational diabetes in overweight non-obese women: bioelectrical impedance analysis, metabolic aspects, obstetric and neonatal outcomes - a randomized and open-label, placebo-

See these in context on the Inositol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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