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Dietary supplement

Chlorophyll 100 mg Ingredients & Drug Interactions

by The Vitamin Shoppe

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Chlorophyll 100 mg is a dietary supplement by The Vitamin Shoppe with 2 active ingredients. Its ingredients are commonly taken for preventing or treating copper deficiency, supporting red blood cell formation, bone and connective tissue health.Based on those ingredients, 366 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Sodium Copper Chlorophyll, Copper. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Chlorophyll 100 mg by The Vitamin Shoppe

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 2 active ingredients: copper and sodium copper chlorophyll. The copper serves as a mineral supplement to prevent or correct copper deficiency.

Sodium copper chlorophyll is a semi-synthetic form of chlorophyll, the green pigment found in plants. The capsule also contains inactive ingredients — rice flour, gelatin, and magnesium stearate — which help form and stabilize the capsule.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Green superfood supplement.
  • We looked for evidence on: Body odor, Copper deficiency, Fecal odor, Urinary odor, Wound healing, Detoxification — and 2 related terms.
  • The strongest evidence on file: Copper is rated "Likely Effective" for Copper deficiency (Natural Medicines).
  • Also on file: Chlorophyllin is rated "Possibly Ineffective" for Urinary odor.
  • Also on file: Chlorophyllin is rated "Insufficient Reliable Evidence To Rate" for Wound healing, Body odor, Fecal odor.

Copper is well established for treating copper deficiency. For other uses, the evidence is limited: it's rated possibly ineffective for Alzheimer's disease, and there's insufficient reliable evidence to rate it for acne, chemotherapy-related anemia, or brain tumors.

Sodium copper chlorophyll has weaker evidence overall. It's rated possibly ineffective for reducing urinary odor, and there's insufficient reliable evidence for acne, cancer prevention, constipation, gas, or low white blood cell count.

The evidence, ingredient by ingredient Copper Chlorophyllin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Copper is safe in food and standard supplement amounts, but excess copper can be toxic — stick to recommended doses. The facts note that copper is needed in pregnancy, but stay within recommended amounts and avoid high-dose supplements without medical guidance.

Rare side effects include contact dermatitis from copper. Sodium copper chlorophyll is generally well tolerated short-term, though quality evidence and long-term safety data are limited.

Topical chlorophyll cream has caused dermatitis, and oral chlorophyll can cause photosensitization and, in case reports, a condition called pseudoporphyria with blistering. The safety data advises against use during pregnancy and breastfeeding, since there isn't enough reliable information.

Side effects, ingredient by ingredient Copper Chlorophyllin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Chlorophyllin, Copper.
  • The most serious interaction on file is rated Moderate.
  • For scale: 366 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before taking this product if you're on penicillamine (Cuprimine, Depen) — Moderate interaction requiring 2-hour separation. If you use photosensitizing drugs, there's a Moderate risk of increased sun sensitivity.

Oral contraceptives may raise your copper levels (Minor interaction).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is mainly useful if you have copper deficiency. If you take penicillamine or oral contraceptives, you need to check with us first — the interactions are real.

If you take any photosensitizing medication (one that makes you sun-sensitive), talk to your pharmacist before starting. Run your full medication list through the checker on this page.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 20, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Chlorophyll 100 mg, straight from the product label.

Brand The Vitamin Shoppe
Barcode (UPC) 766536026272
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Nov 20, 2017
DSLD ID 80310
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Chlorophyll 100 mg by The Vitamin Shoppe, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
766536026272
IngredientAmount% DV
Copper4 mg444%
Sodium Copper Chlorophyll100 mg--

Other ingredients: Rice Flour, Gelatin, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Green food Superfood

Actual size

Visit www.vitaminshoppe.com or call 1-800-223-1216 for more information and to reorder.

FDA Statement of Identity

Dietary Supplement

Formulation

Gluten free Dairy free Soy free Nut free

Does Not Contain: Corn, wheat, gluten, sugar, soy, dairy, citrus, fish, preservatives, artificial colors or flavors.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take one (1) capsule up to twice daily, preferably with meals.

Precautions

Warning: Consult your healthcare provider prior to use if you are pregnant, nursing, taking any medication or have any medical conditions.

Keep out of reach of children.

Tamper evident Do not use if outer seal is broken or missing.

Storage

Store in a cool, dry place.

General

Item No. VS-2627 1757327 ER 37

See for yourself

Chlorophyll 100 mg by The Vitamin Shoppe label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Chlorophyll 100 mg by The Vitamin Shoppe

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Copper

Interacts with
31 drugs
4 mg per serving Form: Sodium Copper Chlorophyllin

Copper is an essential trace mineral your body needs in small amounts for making red blood cells, supporting nerves and bones, and helping enzymes wor...

Copper monograph & interactions

Sodium Copper Chlorophyll

Interacts with
335 drugs
100 mg per serving

Chlorophyllin is a water-soluble, semi-synthetic form of chlorophyll most often used to help control body and fecal odor and to support wound healing....

Sodium Copper Chlorophyll monograph & interactions

Other (inactive) ingredients: Rice Flour, Gelatin, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Chlorophyll 100 mg by The Vitamin Shoppe Drug Interactions

Want to check YOUR meds against Chlorophyll 100 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
366Drugs
336 Moderate 30 Minor

Ingredients driving the most interactions

Copper 31

Each ingredient & the kinds of drugs it affects

For each ingredient in Chlorophyll 100 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Sodium Copper Chlorophyll1 drug type · 335 drugs

Photosensitizing Drugs

Theoretically, concomitant use of chlorophyllin with photosensitizing drugs may have additive effects.
Chlorophyllin is a semi-synthetic derivative of chlorophyll. Chlorophyll has been reported to cause photosensitization. Orally, chlorophyll has also been associated with the development of pseudoporphyria in multiple case reports.

Likelihood Probable Evidence B

Copper2 drug types · 31 drugs

Penicillamine (Cuprimine, Depen)

Theoretically, taking copper with penicillamine might decrease the absorption of penicillamine; separate dosing by at least 2 hours.
Copper chelates penicillamine, which decreases its absorption and may reduce its clinical effects.

Likelihood Probable Evidence D
Contraceptive Drugs

Theoretically, taking copper with contraceptive drugs might increase the levels and toxic effects of copper.
A meta-analysis of clinical studies suggests that chronic use of oral contraceptives increases serum copper levels by a mean of 57 mcg/dL. In most people, this resulted in levels above the normal reference range for copper.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Chlorophyll 100 mg, from the product label.

The Vitamin Shoppe

See all The Vitamin Shoppe products
Name
Vitamin Shoppe, Inc.
City
Secaucus
State
NJ
ZipCode
07094
Phone Number
1-800-223-1216
Web Address
www.vitaminshoppe.com
Pharmacist Counseling Corner

Chlorophyll 100 mg by The Vitamin Shoppe: Common Questions

Does Chlorophyll 100 mg by The Vitamin Shoppe interact with any medications?
Yes. Based on its ingredients, Chlorophyll 100 mg has a known interaction with 366 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Chlorophyll 100 mg contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant or breastfeeding?
Copper is considered likely safe in recommended amounts during pregnancy, but avoid high doses. Sodium copper chlorophyll, the chlorophyll ingredient, has insufficient safety data in pregnancy and breastfeeding — the facts advise against it during both. Talk with your doctor or pharmacist about what's right for you.
What does the copper in this product actually do?
Copper is an essential mineral your body needs for many functions. This supplement is well-established for treating copper deficiency. For other uses like Alzheimer's disease or acne, the evidence is weak or unclear.
Is this good for detoxing or cleansing?
The product's chlorophyll ingredient is rated possibly ineffective for reducing urinary odor, and there's insufficient evidence for most other common uses like cancer prevention or constipation. It's not established as a detox aid.
What side effects should I watch for?
Copper can rarely cause contact dermatitis (skin irritation). Chlorophyll can cause photosensitization (sun sensitivity), and there are case reports of blistering on hands after oral chlorophyll use. Short-term safety data are better than long-term — we don't have much long-term information.
Will this interact with my diabetes medication?
The facts show people with diabetes have higher copper blood levels than those without, but it's unclear whether extra copper makes diabetes worse. There's no documented interaction with diabetes drugs in our data, but talk to us — we can check your specific medications.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Chlorophyll 100 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Chlorophyll 100 mg label
Sources

Sources & How We Checked

Chlorophyll 100 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 17 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Copper 11 references
  1. Murry JJ, Healy MD. Drug-mineral interactions: a new responsibility for the hospital dietician. J Am Diet Assoc 1991;91:66-73.
  2. Campbell IA, Elmes PC. Ethambutol and the eye: zinc and copper (letter). Lancet 1975;2:711. DOI
  3. Segal S, Kaminski S. Drug-nutrient interactions. American Druggist 1996 Jul;42-8.
  4. Kozak SF, Inderlied CB, Hsu HY, et al. The role of copper on ethambutol's antimicrobial action and implications for ethambutol-induced optic neuropathy. Diag Microbiol Infect Dis 1998;30:83-7. PubMed
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  6. Cantilena LR, Klaassen CD. The effect of chelating agents on the excretion of endogenous metals. Toxicol Appl Pharmacol 1982;63:344-50.
  7. Babic Z, Tariba B, Kovacic J, Pizent A, Varnai VM, Macan J. Relevance of serum copper elevation induced by oral contraceptives: a meta-analysis. Contraception. 2013 Jun;87(6):790-800. PubMed
  8. Qui Q, Zhang F, Zhu W, Wu J, Liang M. Copper in diabetes mellitus: a meta-analysis and systematic review of plasma and serum studies. Biol Trace Elem Res 2017;177(1):53-63.
  9. Walker-Smith PK, Keith DJ, Kennedy CT, Sansom JE. Allergic contact dermatitis caused by copper. Contact Dermatitis 2016;75(3):186-7. PubMed
  10. Gallentine A. Third-degree burn on the neuropathic lower extremity in a patient with diabetes while wearing a copper-containing compression sock: a case report. Wound Manag Prev 2021;67(12):26-29. DOI
  11. Chung KJ, Chin YM, Wong MS, Sanmugam A, Singaravel S, Nah SA. Effectiveness of table salt versus copper sulphate in treating umbilical granuloma: A pilot randomized controlled trial. J Pediatr Surg 2022;57(2):261-265. PubMed

See these in context on the Copper monograph →

Chlorophyllin 6 references
  1. Nahata MC, Slencsak CA, Kamp J. Effect of chlorophyllin on urinary odor in incontinent geriatric patients. Drug Intell Clin Pharm 1983;17:732-4. PubMed
  2. Mathews-Roth MM. Carotenoids in erythropoietic protoporphyria and other photosensitivity diseases. Ann N Y Acad Sci, 1993; 691:127-38. PubMed
  3. Belen'kii, G. B. and Krikun, B. L. [Treatment of herpes simplex and herpes zoster by chlorophyll preparations]. Sov.Med. 1971;34(1):151-152.
  4. Rossi E, Borchard K, Cole JM. Pseudoporphyria following self-medication with chlorophyll. Australas J Dermatol. 2015 Feb;56(1):47-8. PubMed
  5. Zhao CY, Frew JW, Muhaidat J, et al. Chlorophyll-induced pseudoporphyria with ongoing photosensitivity after cessation - a case series of four patients. J Eur Acad Dermatol Venereol 2016;30(7):1239-42. PubMed
  6. Tomankova K, Kejlova K, Binder S, et al. In vitro cytotoxicity and phototoxicity study of cosmetics colorants. Toxicol In Vitro. 2011 Sep;25(6):1242-50. PubMed

See these in context on the Chlorophyllin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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