Cinnamon Formula 1000 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Cinnamon Formula 1000 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Cinnamon Formula 1000 mg is a dietary supplement by Longevity Premier with 1 active ingredient. Its ingredients are commonly taken for blood sugar support, digestive upset, antioxidant support.Based on those ingredients, 585 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Cinnamon Glucose Formula. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Cinnamon Formula 1000 mg by Longevity Premier
Ask about any prescription or over-the-counter medication and we check it for interactions with Cinnamon Formula 1000 mg by Longevity Premier — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Cinnamon Formula 1000 mg by Longevity Premier
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This product contains three active ingredients: bitter melon extract, Ceylon cinnamon extract, and a proprietary herbal blend. Bitter melon extract is traditionally used in herbal medicine, while Ceylon cinnamon extract is included as a concentrated form of cinnamon.
The product also contains cellulose, an inactive ingredient used as a filler.
Does it work?
Not established
The evidence for this product's effectiveness isn't established in the data we hold. Bitter melon has insufficient reliable evidence to rate for amenorrhea, athletic performance, liver disease, constipation, diabetes, and dyspepsia.
Ceylon cinnamon extract also has insufficient reliable evidence for amenorrhea, angina, common cold, diabetes, diarrhea, and dyslipidemia. We can't speak to how well this formula works for its intended purpose based on current clinical evidence.
How safe is it?
Well-documented data
Bitter melon is generally well tolerated when taken in supplement doses, though some people report gastrointestinal side effects like nausea, vomiting, diarrhea, constipation, heartburn, and abdominal discomfort — occurring in about 3% to 16% of trial participants. Rare serious effects include hypoglycemic coma and seizures in children.
Ceylon cinnamon is generally safe at food amounts, but at high supplement doses there's concern about liver stress from its coumarin content. A rash and contact dermatitis have been reported in rare cases.
Regarding pregnancy: bitter melon is traditionally avoided because seeds and high doses may cause uterine or other harmful effects. Ceylon cinnamon is likely safe at food amounts but best avoided at medicinal doses during pregnancy.
There isn't enough reliable safety information for bitter melon while breastfeeding; talk with your doctor or pharmacist before use.
Meds to double-check
Moderate interaction found
Check with your pharmacist if you take antidiabetes drugs (bitter melon and cinnamon both lower blood sugar and could cause dangerously low levels), hepatotoxic drugs (cinnamon may add to liver stress), P-glycoprotein substrates (bitter melon may increase their levels), or pazopanib (a cancer drug that bitter melon may interfere with).
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
This product isn't for you if you take diabetes medications or pazopanib without discussing it first with your pharmacist — the blood sugar interactions are real. It's also not ideal if you're taking medications that stress the liver or depend on P-glycoprotein absorption.
If you're pregnant or breastfeeding, check with your doctor before starting. For anyone else considering it, have a pharmacist review your exact medication list.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Cinnamon Formula 1000 mg, straight from the product label.
| Brand | Longevity Premier |
|---|---|
| Barcode (UPC) | 850004667088 |
| Net contents | 120 Veggie Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Nov 22, 2022 |
| DSLD ID | 277526 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Cinnamon Formula 1000 mg by Longevity Premier, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Herbal Blend | 0 NP | -- |
| Bitter Melon Extract | 0 NP | -- |
| Cinnamon Glucose Formula | 1000 mg | -- |
| Ceylon Cinnamon Extract | 0 NP | -- |
Other ingredients: Cellulose
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use: As a dietary supplement, take two capsules once or twice daily, preferably 30 minutes before or 30 minutes after a meal.
Precautions
Caution: Do not exceed recommended dose.
Do not exceed this product if you have type 1 diabetes. This product is not for those who are prone to bleeding, dizziness, constipation, or with bleeding hemorrhoids, itchy skin, mood swing/ disorder, and sensitive physique.
Pregnant or nursing mothers, children under the age of 18, and individuals with a known health condition especially liver or kidney should not use this product without consulting a physician first. Please take different supplements separately.
Pregnant or nursing mothers, children under the age of 18, and individuals with a known health condition especially liver or kidney should not use this product without consulting a physician first. Please take different supplements separately. Keep out of reach of children.
Please take different supplements separately.
Seals/Symbols
Made In The USA GMP Good Manufacturing Practice
Formulation
GMO Free
Drug free
Supports glucose metabolism
Notice: Herbs may have a distinct natural odor and color variation
100% Quality Guaranteed
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FDA Statement of Identity
Dietary Supplement
General Statements
Available at: LongevityPremier.com
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Cinnamon Formula 1000 mg by Longevity Premier label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Cinnamon Formula 1000 mg by Longevity Premier
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Veggie Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Cinnamon Glucose Formula
Interacts with442 drugs
Cassia cinnamon is the common, inexpensive cinnamon used in cooking, and it is also taken as a supplement, most often for blood sugar support. The evi...
Cinnamon Glucose Formula monograph & interactions- › Proprietary Herbal Blend
- › Bitter Melon Extract
- › Ceylon Cinnamon Extract
Other (inactive) ingredients: Cellulose. These complete the product’s ingredient list but are not active constituents.
Cinnamon Formula 1000 mg by Longevity Premier Drug Interactions
HelloPharmacist Interaction Report
Cinnamon Formula 1000 mg by Longevity Premier has documented interactions with several medication types.
The most serious concern involves bitter melon extract and antidiabetes drugs — a Major interaction. Bitter melon can lower blood sugar, and when combined with diabetes medications, you run the risk of blood sugar dropping too low (hypoglycemia).
Both bitter melon and Ceylon cinnamon extract may lower blood glucose and have additive effects with antidiabetes drugs; dose adjustments to your diabetes medication might be necessary.
Read the full breakdown — every affected drug type, severity by severity
Bitter melon also interacts moderately with P-glycoprotein substrates (medications whose absorption depends on a specific intestinal pump). Bitter melon may increase their levels in your body, potentially raising side effects.
It also carries a moderate interaction with pazopanib, a cancer medication — theoretically increasing its levels and adverse effects. Ceylon cinnamon extract has a moderate interaction with hepatotoxic drugs (medications that can stress the liver); large doses of cinnamon might cause additive liver damage over time.
We could not check the proprietary herbal blend because we hold no data for it. Run your exact medications through the interaction checker on this page before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Cinnamon Formula 1000 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Cinnamon Formula 1000 mg interact with 585 drugs. Click any drug to see the details.
1 of the 1 ingredient in Cinnamon Formula 1000 mg interact with drugs. Each result below shows which ingredient is responsible. Cinnamon Glucose Formula
AmprenavirAgenerase
How Amprenavir interacts with Cinnamon Formula 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon ExtractP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Extract + Amprenavir interactionAnidulafunginEraxis
How Anidulafungin interacts with Cinnamon Formula 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Ceylon Cinnamon ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Ceylon Cinnamon Extract + Anidulafungin interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Cinnamon Formula 1000 mg — through 2 ingredients. Tap an ingredient for the detail:
Bitter Melon ExtractP-glycoprotein Substrates, Antidiabetes Drugs Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Extract + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionCeylon Cinnamon ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, cassia cinnamon may have additive effects with antidiabetes drugs.
Read the full Ceylon Cinnamon Extract + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionApixabanEliquis
How Apixaban interacts with Cinnamon Formula 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon ExtractP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Extract + Apixaban interactionApomorphineAPO-go, APO-go Pen, APO-go PFS, Apokyn, Uprima
How Apomorphine interacts with Cinnamon Formula 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon ExtractP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Extract + Apomorphine interactionApomorphine HydrochlorideKynmobi
How Apomorphine Hydrochloride interacts with Cinnamon Formula 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon ExtractP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Extract + Apomorphine Hydrochloride interactionAprocitentanTryvio
How Aprocitentan interacts with Cinnamon Formula 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Ceylon Cinnamon ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Ceylon Cinnamon Extract + Aprocitentan interactionArmodafinilNuvigil
How Armodafinil interacts with Cinnamon Formula 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon ExtractP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Extract + Armodafinil interactionAsparaginase Erwinia Chrysanthemi (recombinant)-rywnRylaze
How Asparaginase Erwinia Chrysanthemi (recombinant)-rywn interacts with Cinnamon Formula 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Ceylon Cinnamon ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Ceylon Cinnamon Extract + Asparaginase Erwinia Chrysanthemi (recombinant)-rywn interactionAspirin, Caffeine, Phenacetin, PropoxypheneMargesic Comp. 65
How Aspirin, Caffeine, Phenacetin, Propoxyphene interacts with Cinnamon Formula 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Ceylon Cinnamon ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Ceylon Cinnamon Extract + Aspirin, Caffeine, Phenacetin, Propoxyphene interactionAtogepantQulipta
How Atogepant interacts with Cinnamon Formula 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon ExtractP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Extract + Atogepant interactionAtorvastatinAtorvaliq
How Atorvastatin interacts with Cinnamon Formula 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Ceylon Cinnamon ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Ceylon Cinnamon Extract + Atorvastatin interactionAtorvastatin CalciumLipitor
How Atorvastatin Calcium interacts with Cinnamon Formula 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Ceylon Cinnamon ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Ceylon Cinnamon Extract + Atorvastatin Calcium interactionAtropine, Morphine SulfateAtropine, Morphine Sulfate
How Atropine, Morphine Sulfate interacts with Cinnamon Formula 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon ExtractP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Extract + Atropine, Morphine Sulfate interactionAvacopanTavneos
How Avacopan interacts with Cinnamon Formula 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Ceylon Cinnamon ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Ceylon Cinnamon Extract + Avacopan interactionAvatrombopag MaleateDoptelet
How Avatrombopag Maleate interacts with Cinnamon Formula 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon ExtractP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Extract + Avatrombopag Maleate interactionAzamuneImmunoprin
How Azamune interacts with Cinnamon Formula 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Ceylon Cinnamon ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Ceylon Cinnamon Extract + Azamune interactionAzathioprineAzamune, Imuran
How Azathioprine interacts with Cinnamon Formula 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Ceylon Cinnamon ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Ceylon Cinnamon Extract + Azathioprine interactionBaricitinibOlumiant
How Baricitinib interacts with Cinnamon Formula 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Ceylon Cinnamon ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Ceylon Cinnamon Extract + Baricitinib interactionBazedoxifene Acetate, Conjugated EstrogensDuavee
How Bazedoxifene Acetate, Conjugated Estrogens interacts with Cinnamon Formula 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon ExtractP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Extract + Bazedoxifene Acetate, Conjugated Estrogens interactionBeclometasone DipropionateBecotide
How Beclometasone Dipropionate interacts with Cinnamon Formula 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon ExtractP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Extract + Beclometasone Dipropionate interactionBeclomethasoneBeclovent, Vanceril
How Beclomethasone interacts with Cinnamon Formula 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon ExtractP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Extract + Beclomethasone interactionBeclomethasone DipropionateQNASL, Qvar
How Beclomethasone Dipropionate interacts with Cinnamon Formula 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon ExtractP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Extract + Beclomethasone Dipropionate interactionBelinostatBeleodaq
How Belinostat interacts with Cinnamon Formula 1000 mg — through 2 ingredients. Tap an ingredient for the detail:
Bitter Melon ExtractP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Extract + Belinostat interactionCeylon Cinnamon ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Ceylon Cinnamon Extract + Belinostat interactionBenzhydrocodone, AcetaminophenApadaz
How Benzhydrocodone, Acetaminophen interacts with Cinnamon Formula 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Ceylon Cinnamon ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Ceylon Cinnamon Extract + Benzhydrocodone, Acetaminophen interactionBerotralstat HydrochlorideOrladeyo
How Berotralstat Hydrochloride interacts with Cinnamon Formula 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon ExtractP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Extract + Berotralstat Hydrochloride interactionBetamethasoneCelestone, Diprolene AF, Diprosone
How Betamethasone interacts with Cinnamon Formula 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon ExtractP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Extract + Betamethasone interactionBetamethasone DipropionateSernivo
How Betamethasone Dipropionate interacts with Cinnamon Formula 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon ExtractP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Extract + Betamethasone Dipropionate interactionBetamethasone Dipropionate, CalcipotrieneEnstilar, Wynzora
How Betamethasone Dipropionate, Calcipotriene interacts with Cinnamon Formula 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon ExtractP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Extract + Betamethasone Dipropionate, Calcipotriene interactionBetamethasone ValerateLuxiq
How Betamethasone Valerate interacts with Cinnamon Formula 1000 mg — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon ExtractP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Extract + Betamethasone Valerate interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Cinnamon Formula 1000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Cinnamon Glucose Formula
Antidiabetes Drugs
Theoretically, cassia cinnamon may have additive effects with antidiabetes drugs.
Cassia cinnamon may lower blood glucose levels, and have additive effects in patients treated with antidiabetic agents. Dose adjustments to diabetes medications might be necessary.
Hepatotoxic Drugs
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
There is some concern that ingesting large amounts of cassia cinnamon for an extended duration might cause hepatotoxicity in some people. Cassia cinnamon contains coumarin, which can cause hepatotoxicity in animal models. In humans, very high doses of coumarin from 50-7000 mg/day can result in hepatotoxicity that resolves when coumarin use is discontinued. Lower amounts might also cause liver problems in sensitive people, such as those with liver disease or those taking potentially hepatotoxic agents.
Brand information
Manufacturer and brand details for Cinnamon Formula 1000 mg, from the product label.
Longevity Premier
See all Longevity Premier products- Name
- Longevity Premier Nutraceuticals Inc
- Street Address
- 325 Chestnut St, 8th FI
- City
- Philadelphia
- State
- PA
- ZipCode
- 19106
- Phone Number
- 1-877-529-1118
- Web Address
- LongevityPremier.com
Cinnamon Formula 1000 mg by Longevity Premier: Common Questions
Does Cinnamon Formula 1000 mg by Longevity Premier interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this product lower my blood sugar?
What are the most common side effects I might notice?
Is this safe to take while pregnant?
Can I take this while breastfeeding?
What's in the proprietary herbal blend?
Could this hurt my liver?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Cinnamon Formula 1000 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Cinnamon Formula 1000 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Cassia Cinnamon
Interacts with 442 drugsCassia cinnamon is the common, inexpensive cinnamon used in cooking, and it is also taken as a supplement, most often for blood sugar support. The evidence for its health benefits is mixed a...
Read the full Cassia Cinnamon monograph → Herb & supplement monographBitter Melon
Interacts with 282 drugsBitter melon is a tropical fruit eaten as food and used in traditional medicine, most often for blood sugar control. While some small studies hint it may modestly lower blood sugar, the evid...
Read the full Bitter Melon monograph →Sources & How We Checked
Cinnamon Formula 1000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 38 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Bitter Melon 18 references
- Leatherdale B, Panesar RK, Singh G, et al. Improvement in glucose tolerance due to Momordica charantia. Br Med J (Clin Res Ed) 1981;282:1823-4.
- Welihinda J, et al. Effect of Momordica charantia on the glucose tolerance in maturity onset diabetes. J Ethnopharmacol 1986;17:277-82. PubMed
- Srivastava Y, Venkatakrishna-Bhatt H, Verma Y, et al. Antidiabetic and adaptogenic properties of Momordica charantia extract: An experimental and clinical evaluation. Phytother Res 1993;7:285-9.
- Baldwa VS, Bhandari CM, Pangaria A, Goyal RK. Clinical trial in patients with diabetes mellitus of an insulin-like compound obtained from plant sources. Ups J Med Sci 1977;82:39-41. PubMed
- Aslam M, Stockley IH. Interaction between curry ingredient (karela) and drug (chlorpropamide). Lancet 1979:1:607. PubMed
- Ahmad N, Hassan MR, Halder H, Bennoor KS. Effect of Momordica charantia (Karolla) extracts on fasting and postprandial serum glucose levels in NIDDM patients (abstract). Bangladesh Med Res Counc Bull 1999;25:11-3.
- Basch E, Gabardi S, Ulbricht C. Bitter melon (Momordica charantia): a review of efficacy and safety. Am J Health Syst Pharm 2003;60:356-9. PubMed
- Yin RV, Lee NC, Hirpara H, Phung OJ. T. The effect of bitter melon (Mormordica charantia) in patients with diabetes mellitus: s systematic review and meta-analysis. Nutr Diabetes. 2014;4:e145.
- Rahman IU, Khan RU, Rahman KU, Bashir M. Lower hypoglycemic but higher antiatherogenic effects of bitter melon than glibenclamide in type 2 diabetic patients. Nutr J. 2015;14:13. PubMed
- Alam MA, Uddin R, Subhan N, Rahman MM, Jain P, Reza HM. Beneficial role of bitter melon supplementation in obesity and related complications in metabolic syndrome. J Lipids. 2015;2015:496169. PubMed
- Konishi T, Satsu H, Hatsugai Y, et al. Inhibitory effect of a bitter melon extract on the P-glycoprotein activity in intestinal Caco-2 cells. Br J Pharmacol. 2004;143(3):379-87. PubMed
- Peter EL, Kasali FM, Deyno S, et al. Momordica charantia L. lowers elevated glycaemia in type 2 diabetes mellitus patients: Systematic review and meta-analysis. J Ethnopharmacol. 2019;231:311-24. doi: 10.1016/j.jep.2018.10.033. PubMed
- Cortez-Navarrete M, Martínez-Abundis E, Pérez-Rubio KG, González-Ortiz M, Méndez-Del Villar M. Momordica charantia administration improves insulin secretion in type 2 diabetes mellitus. J Med Food. 2018;21(7):672-7. doi: 10.108
- Kim SK, Jung J, Jung JH, et al. Hypoglycemic efficacy and safety of Momordica charantia (bitter melon) in patients with type 2 diabetes mellitus. Complement Ther Med. 2020 Aug;52:102524. doi: 10.1016/j.ctim.2020.102524. PubMed
- Unsal O, Sütcüoglu O, Yazici O. Dangerous interaction of bitter melon (Momordica charantia) with pazopanib: a case of acute pancreatitis. J Oncol Pharm Pract 2022;28(2):486-8.
- Bae W, Kim S, Choi J, et al. Acute interstitial nephritis associated with ingesting a Momordica charantia extract: a case report. Medicine (Baltimore) 2021;100(27):e26606. PubMed
- Chattopadhyay K, Wang H, Kaur J, et al. Effectiveness and Safety of Ayurvedic Medicines in Type 2 Diabetes Mellitus Management: A Systematic Review and Meta-Analysis. Front Pharmacol. 2022;13:821810. Published 2022 Jun 8. PubMed
- Kim B, Lee HS, Kim HJ, et al. Momordica charantia (bitter melon) efficacy and safety on glucose metabolism in Korean prediabetes participants: a 12-week, randomized clinical study. Food Sci Biotechnol 2022;32(5):697-704. PubMed
Cassia Cinnamon 20 references
- Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
- Khan A, Safdar M, Ali Khan M, et al. Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care 2003;26:3215-8. PubMed
- De Benito V, Alzaga R. Occupational allergic contact dermatitis from cassia (Chinese cinnamon) as a flavouring agent in coffee. Contact Dermatitis 1999;40:165. PubMed
- Drake TE, Maibach HI. Allergic contact dermatitis and stomatitis caused by a cinnamic aldehyde-flavored toothpaste. Arch Dermatol 1976;112:202-3.
- Press release. Cinnamon capsules to reduce blood sugar are medicinal products! Efficacy has not been scientifically proven - some products contain high levels of coumarin. Federal Institute of Risk Assessment (BfM), Germany, November 11, 2006. Available a
- Felter SP, Vassallo JD, Carlton BD, Daston GP. A safety assessment of coumarin taking into account species-specificity of toxicokinetics. Food Chem Toxicol 2006;44:462-75. PubMed
- Crawford P. Effectiveness of cinnamon for lowering hemoglobin A1C in patients with type 2 diabetes: a randomized, controlled trial. J Am Board Fam Med 2009;22:507-12. PubMed
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