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Dietary supplement

Coccinia Ingredients & Drug Interactions

by Hawaii Pharm

Coccinia label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Coccinia against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Coccinia is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for blood sugar support, digestive complaints, skin conditions.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are certified organic Coccinia extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Coccinia by Hawaii Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Coccinia by Hawaii Pharm — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Coccinia by Hawaii Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This liquid contains one active ingredient: certified organic ivy gourd extract. Ivy gourd is a plant used traditionally to help manage blood sugar.

The liquid itself is made up of vegetable palm glycerin, pharmaceutical-grade alcohol, and artesian Hawaiian purified water — these are inactive ingredients that serve as the extract's base.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Ivy Gourd's overall clinical evidence instead.

Moderate

Some clinical evidence supports Ivy Gourd for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Diabetes — rated "Possibly Effective" (Natural Medicines).

Ivy gourd extract is rated possibly effective for helping with diabetes. That means there's some evidence it may help, but the research isn't definitive yet.

If you're considering it for blood sugar support, talk it over with your doctor to see whether it fits your overall plan.

The evidence, ingredient by ingredient Ivy Gourd

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Ivy gourd leaf is generally well tolerated when taken by mouth. Some people report mild nausea, headache, or drowsiness, but these are uncommon.

The safety data advises against using medicinal amounts during pregnancy or while breastfeeding — there isn't enough information to know it's safe at those doses. If you're pregnant, planning to become pregnant, or nursing, talk with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Ivy Gourd

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Ivy Gourd.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any antidiabetes drug — insulin, metformin, sulfonylureas, GLP-1 agonists, or any other blood sugar medication — check your exact medication with your doctor or pharmacist before taking this product. Ivy gourd may lower blood glucose and could increase the risk of low blood sugar when combined with these drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Coccinia may be worth considering if you're looking for additional blood sugar support and your doctor agrees. Because it can lower blood glucose, anyone on diabetes medication needs to check with their own doctor or pharmacist before starting — and monitor blood sugar closely if they do.

This isn't a replacement for prescribed diabetes care.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Coccinia, straight from the product label.

Brand Hawaii Pharm
Barcode (UPC) 0787699242002
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Oct 23, 2020
DSLD ID 237899
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Coccinia by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.7 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
0787699242002
IngredientAmount% DV
certified organic Coccinia extract970 mg--

Other ingredients: Vegetable Palm Glycerin, pharmaceutical grade Alcohol, artesian Hawaiian purified Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Hawaii Pharm Herbal Extract Highest quality since 2008

Made with Aloha!

Formulation

Contains no GMO, gluten, artificial colors, heavy metals, preservatives, pesticides, fertilizers.

Super concentrated liquid herbal extract. Dry herb/menstruum ratio: 1:3.

Manufactured in an FDA registered facility.

Non GMO Gluten free

Made in USA, Hawaii

Suggested/Recommended/Usage/Directions

Directions for use: Shake well before using. Take about 20-30 drops (0.7-1 ml, one full squeeze of the dropper bulb) to 2-4 oz of juice or water up to 4 times per day.

Precautions

Warning: Keep out of the reach of children.

May have contraindications. We recommend to seek expert medical advice before taking.

Do not use if you are allergic to any ingredients.

Consult a physician before using during pregnancy, if nursing or taking any medications.

Do not use if seal is broken or missing.

Storage

Store in a cool dry place.

Formula

(Coccinia cordifolia)

FDA Statement of Identity

Herbal Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

FDA Registered Facility Made in United States of America USA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Coccinia by Hawaii Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Coccinia label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Coccinia by Hawaii Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.7 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Certified organic Coccinia extract

Interacts with
86 drugs
970 mg per serving

Ivy gourd is a tropical vine widely eaten as a vegetable and used in traditional medicine, most often for blood sugar support. Early human research hi...

Certified organic Coccinia extract monograph & interactions

Other (inactive) ingredients: Vegetable Palm Glycerin, Pharmaceutical grade Alcohol, Artesian Hawaiian purified Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Coccinia by Hawaii Pharm Drug Interactions

Want to check YOUR meds against Coccinia?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

certified organic Coccinia extract 86

Individual Drug Interactions

The ingredients in Coccinia interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Coccinia interact with drugs. Each result below shows which ingredient is responsible. certified organic Coccinia extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Coccinia with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

certified organic Coccinia extract1 drug type · 86 drugs

Antidiabetes Drugs

Ivy gourd may lower blood glucose levels and might have additive effects when used with antidiabetes drugs. This might increase the risk of hypoglycemia in some patients. Monitor blood glucose levels closely.

Likelihood Probable Evidence A
certified organic Coccinia extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Coccinia, from the product label.

Hawaii Pharm

See all Hawaii Pharm products
Name
Hawaii Pharm LLC
City
Honolulu
State
HI
ZipCode
96815
Web Address
www.hawaiipharm.com
Pharmacist Counseling Corner

Coccinia by Hawaii Pharm: Common Questions

Does Coccinia by Hawaii Pharm interact with any medications?
Yes. Based on its ingredients, Coccinia has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Coccinia contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does ivy gourd do?
Ivy gourd is a plant traditionally used to help support blood sugar levels. This product rates it as possibly effective for diabetes, which means there's some evidence it may help, but research is still developing.
Can I take this if I'm pregnant or breastfeeding?
The safety data advises against medicinal amounts of ivy gourd during pregnancy and while breastfeeding — there isn't enough information to know it's safe. Talk with your doctor or pharmacist for personalized advice before taking it.
What side effects might I notice?
Ivy gourd leaf is generally well tolerated. Some people report mild nausea, headache, or drowsiness, but these are uncommon.
Is this safe to take with my diabetes medication?
That depends on your specific medication and dose. Because ivy gourd can lower blood sugar, it may add to the effect of your diabetes drug and raise the risk of low blood sugar. Check with your doctor or pharmacist before starting, and if you do take it together, monitor your blood glucose closely.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Coccinia is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Coccinia label
Go deeper

The Full Monographs Behind Coccinia’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Ivy Gourd

Interacts with 86 drugs

Ivy gourd is a tropical vine widely eaten as a vegetable and used in traditional medicine, most often for blood sugar support. Early human research hints it may modestly lower blood sugar, b...

Read the full Ivy Gourd monograph →
Sources

Sources & How We Checked

Coccinia's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Ivy Gourd 5 references
  1. Khan AK, AKhtar S, Mahtab H. Treatment of diabetes mellitus with Coccinia indica. Br Med J 1980;280:1044. PubMed
  2. Munasinghe MAAK, Abeysena C, Yaddehige IS, et al. Blood sugar lowering effect of Coccinia grandis (L.) J. Voight: path for a new drug for diabetes mellitus. Exp Diabetes Res 2011; doi: 10.1155/2011/978762.
  3. Venkateswaran, S. and Pari, L. Effect of Coccinia indica leaf extract on plasma antioxidants in streptozotocin- induced experimental diabetes in rats. Phytother.Res 2003;17(6):605-608.
  4. Kuriyan, R., Rajendran, R., Bantwal, G., and Kurpad, A. V. Effect of supplementation of Coccinia cordifolia extract on newly detected diabetic patients. Diabetes Care 2008;31(2):216-220.
  5. Wasana KGP, Attanayake AP, Weerarathna TP, Jayatilaka KAPW. Efficacy and safety of a herbal drug of Coccinia grandis (Linn.) Voigt in patients with type 2 diabetes mellitus: A double blind randomized placebo controlled clinical trial. Phytomedicine. 2021 PubMed

See these in context on the Ivy Gourd monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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