Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Coconut Oil Ingredients & Drug Interactions

by Nature's Craft

Coconut Oil label
See full label image
Softgel Capsule Category: Botanical
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Coconut Oil against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Coconut Oil is a dietary supplement by Nature's Craft with 1 active ingredient. Its ingredients are commonly taken for skin and hair care, source of dietary fats (mcts), hydration with coconut water.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Extra Virgin Coconut Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Coconut Oil by Nature's Craft

Ask about any prescription or over-the-counter medication and we check it for interactions with Coconut Oil by Nature's Craft — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Coconut Oil by Nature's Craft

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Nature's Craft Coconut Oil is a single-ingredient softgel: extra virgin coconut oil. That's the whole active package.

The capsule itself is made from bovine gelatin, glycerin, purified water, and titanium dioxide—the standard inert stuff that holds the oil and makes it easy to swallow.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Coconut product and its label doesn't state a use — see Coconut's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for coconut oil isn't solid yet. We hold ratings of insufficient reliable evidence for diabetes, high cholesterol, obesity, and lichen planus—meaning the research so far doesn't give us a clear answer on whether it works for any of those.

If you're considering it for one of those reasons, talk with your pharmacist about what the current science actually supports.

The evidence, ingredient by ingredient Coconut

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Coconut oil from food is generally well tolerated, but here's the catch: concentrated supplement doses haven't been studied much, so your doctor should weigh in before you take high-dose pills. The main real risk is allergic reaction.

Coconut causes hives, urticaria (hive-like skin bumps), and in sensitive people, anaphylaxis—a serious whole-body reaction. About half of reported coconut reactions involve anaphylaxis, so if you have a known coconut allergy or sensitivity, this product isn't for you.

For pregnancy and breastfeeding, the data says it's likely safe, though if you're nursing and have a coconut allergy, be aware that the oil can pass through breast milk and trigger reactions in your baby.

Side effects, ingredient by ingredient Coconut

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Coconut.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take an antidiabetes drug (blood sugar medication), check your exact prescription in the tool below—coconut oil might lower your blood sugar further and raise hypoglycemia risk. For other medication types, no interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

This is straightforward coconut oil in a capsule—one ingredient, minimal fillers. If you're taking a blood sugar medication, check with your pharmacist first; otherwise, the main concern is allergic reaction.

If you have a coconut allergy or sensitivity, skip it. Talk to your pharmacist about whether the evidence supports using it for your specific goal.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Coconut Oil, straight from the product label.

Brand Nature's Craft
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Nov 22, 2024
DSLD ID 321681
Product type Botanical
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Coconut Oil by Nature's Craft, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
60
IngredientAmount% DV
Extra Virgin Coconut Oil1000 mg--

Other ingredients: Bovine Gelatin, Glycerin, Water, Purified, Titanium Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: 1 softgel taken 1 to 2 times daily preferably with meals or as directed by a healthcare professional.

Precautions

Caution: do not exceed recommended dose. Do not use if safety seal is damaged or missing.

Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of the reach of children.

This product is manufactured and packaged in a facility which may also process milk, soy, wheat, egg, peanuts, tree nuts, and crustacean shellfish.

Allergen warning: contains tree nuts (coconut).

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

Extra virgin Coconut Oil

FDA Statement of Identity

Dietary Supplement

General Statements

Please recycle Follow us on: Twitter, Facebook, Instagram bynaturescraft

Seals/Symbols

Sourced from a GMP Certified Facility 3rd Party Lab Verified

Formulation

Non GMO

Fitness & exercise

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Coconut Oil by Nature's Craft label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Coconut Oil label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Coconut Oil by Nature's Craft

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.

Extra Virgin Coconut Oil

Interacts with
86 drugs
1000 mg per serving

Coconut is a nutritious tropical food enjoyed as oil, water, milk, and flesh, and it is generally safe to eat in normal food amounts. While some uses...

Extra Virgin Coconut Oil monograph & interactions

Other (inactive) ingredients: Bovine Gelatin, Glycerin, Water, Purified, Titanium Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Coconut Oil by Nature's Craft Drug Interactions

Want to check YOUR meds against Coconut Oil?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Minor

Ingredients driving the most interactions

Extra Virgin Coconut Oil 86

Individual Drug Interactions

The ingredients in Coconut Oil interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Coconut Oil interact with drugs. Each result below shows which ingredient is responsible. Extra Virgin Coconut Oil

Each ingredient & the kinds of drugs it affects

For each ingredient in Coconut Oil with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Extra Virgin Coconut Oil1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking coconut with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that coconut milk might increase insulin levels and/or decrease blood glucose levels.

Likelihood Unlikely Evidence D
Extra Virgin Coconut Oil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Coconut Oil, from the product label.

Nature's Craft

See all Nature's Craft products
Name
Nature's Craft
Street Address
239 2nd Ave. S, 2nd floor
City
St. Petersburg
State
FL
ZipCode
33701
Phone Number
408-599-3841
Web Address
shopnaturescraft.com
Pharmacist Counseling Corner

Coconut Oil by Nature's Craft: Common Questions

Does Coconut Oil by Nature's Craft interact with any medications?
Yes. Based on its ingredients, Coconut Oil has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Coconut Oil contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I have a nut allergy?
Coconut is technically a stone fruit, but the US groups it with tree nuts for allergen labeling. If you have a tree nut allergy or any history of reaction to coconut, avoid this product—it can trigger serious allergic reactions including anaphylaxis.
Is this safe to take during pregnancy or while breastfeeding?
The data says coconut oil is likely safe in pregnancy. If you're breastfeeding and take this, the oil will pass into your breast milk, so if your baby has a coconut sensitivity, that's a risk. Talk with your doctor or pharmacist about whether it's right for your situation.
Will this help me lose weight or lower my cholesterol?
We don't have reliable evidence either way. The research so far isn't clear enough to say coconut oil works for obesity or high cholesterol. If that's your goal, ask your pharmacist what the current science supports.
What are the side effects?
Taken by mouth, coconut oil is generally well tolerated with few side effects in most people. The main risk is allergic reaction—hives, skin bumps, or in sensitive individuals, a serious whole-body reaction. If you develop itching, rash, or trouble breathing, stop and seek help right away.
Why does the label say to check with my doctor before taking high-dose supplements?
Concentrated coconut oil supplements haven't been studied as thoroughly as whole food coconut. Your doctor needs to make sure it's safe alongside your other health conditions and medications.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Coconut Oil is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Coconut Oil label
Go deeper

The Full Monographs Behind Coconut Oil’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Coconut

Interacts with 86 drugs

Coconut is a nutritious tropical food enjoyed as oil, water, milk, and flesh, and it is generally safe to eat in normal food amounts. While some uses (like skin moisturizing and hydration) h...

Read the full Coconut monograph →
Sources

Sources & How We Checked

Coconut Oil's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Coconut 10 references
  1. Teuber SS, Peterson WR. Systemic allergic reaction to coconut (Cocos nucifera) in 2 subjects with hypersensitivity to tree nut and demonstration of cross-reactivity to legumin-like seed storage proteins: new coconut and walnut food allergens. J Allergy Cl PubMed
  2. Rosado A, Fernandez-Rivas M, Gonzalez-Mancebo E, et al. Anaphylaxis to coconut. Allergy 2002;57(2):182-3. PubMed
  3. Karmakar PR, Das A, Chatterjee BP. Placebo-controlled immunotherapy with Cocos nucifera pollen extract. Int Arch Allergy Immunol 1994;103(2):194-201. PubMed
  4. Anagnostou K. Coconut Allergy Revisited. Children (Basel). 2017;4(10). pii: E85. PubMed
  5. Cifuentes L, Mistrello G, Amato S, et al. Identification of cross-reactivity between buckwheat and coconut. Ann Allergy Asthma Immunol. 2015;115(6):530-2. PubMed
  6. Michavila Gomez A, Amat Bou M, Gonzalez Cortés MV, Segura Navas L, Moreno Palanques MA, Bartolomé B. Coconut anaphylaxis: Case report and review. Allergol Immunopathol (Madr). 2015;43(2):219-20. PubMed
  7. 21CFR170.3. U.S. Food and Drug Administration Department of Health and Human Services. Updated April 1, 2017. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=170.3
  8. Alatawi KA, Alshubaily FA. Coconut products alleviate hyperglycaemic, hyperlipidimic and nephropathy indices in streptozotocin-induced diabetic wistar rats. Saudi J Biol Sci. 2021;28(8):4224-4231. PubMed
  9. Kruse L, Lor J, Yousif R, Pongracic JA, Fishbein AB. Coconut allergy: Characteristics of reactions and diagnostic predictors in a pediatric tertiary care center. Ann Allergy Asthma Immunol 2021;126(5):562-568.
  10. Pathmanandavel K, Kaur N, Joshi P, Ford LS. Anaphylaxis and allergy to coconut: An Australian pediatric case series. J Allergy Clin Immunol Pract 2020;8(10):3657-3659. PubMed

See these in context on the Coconut monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team