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Dietary supplement

CoQ10 L-Carnitine Magnesium Ingredients & Drug Interactions

by Doctor's Best

CoQ10 L-Carnitine Magnesium label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking CoQ10 L-Carnitine Magnesium against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

CoQ10 L-Carnitine Magnesium is a dietary supplement by Doctor's Best with 3 active ingredients. Its ingredients are commonly taken for preventing or treating magnesium deficiency, constipation, muscle cramps.Based on those ingredients, 475 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Magnesium, Coenzyme Q10, L-Carnitine Fumarate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against CoQ10 L-Carnitine Magnesium by Doctor's Best

Ask about any prescription or over-the-counter medication and we check it for interactions with CoQ10 L-Carnitine Magnesium by Doctor's Best — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of CoQ10 L-Carnitine Magnesium by Doctor's Best

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • “Magnesium” is listed as a grouped ingredient — the label gives one combined amount (200 mg) without saying how much of each component you get.
  • “L-Carnitine Fumarate” is listed as a grouped ingredient — the label gives one combined amount (855 mg) without saying how much of each component you get.

This product contains three active ingredients. Coenzyme Q10 (CoQ10) is a compound your cells make naturally and use for energy production; it's found in higher amounts in heart, kidney, and liver tissue.

L-Carnitine is an amino acid that helps your body transport fatty acids into cells so they can be burned for energy. Magnesium Bisglycinate Chelate buffered is a form of the mineral magnesium bound to the amino acid glycine for absorption.

The remaining ingredients—Modified Cellulose, Microcrystalline Cellulose, Silicon Dioxide, and Magnesium Stearate—are inactive fillers and binders that make up the capsule.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: support energy, muscle mass and muscle recovery.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Exercise-induced muscle soreness, Fatigue, Cancer-related fatigue, Chronic fatigue syndrome (CFS) — and 4 related terms.
  • The closest evidence on file: Coenzyme Q10 is rated "Possibly Ineffective" for Chemotherapy-related fatigue (Natural Medicines).
  • Also on file: Magnesium is rated "Possibly Ineffective" for Athletic performance.
  • Also on file: Coenzyme Q10 is rated "Likely Ineffective" for Athletic performance.

CoQ10 is rated Likely Effective for CoQ10 deficiency and Possibly Effective for fibromyalgia, migraine headaches, congestive heart failure (CHF), and diabetic neuropathy. L-Carnitine is rated Effective for L-carnitine deficiency and Possibly Effective for high cholesterol (hyperlipidemia), CHF, and angina.

Magnesium is rated Effective for indigestion (dyspepsia), constipation, and low magnesium blood levels (hypomagnesemia), and Effective for preventing pre-eclampsia in pregnancy. The evidence we hold does not establish how effective this specific combination is for any single condition.

The evidence, ingredient by ingredient Magnesium Coenzyme Q10 L-carnitine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

CoQ10 is generally well tolerated by most adults. The most common side effects are gastrointestinal — appetite suppression, diarrhea, heartburn, nausea, vomiting — occurring in less than 1% of users; doses above 100 mg split into smaller daily amounts may help.

A small number of trial participants reported headache, dizziness, or insomnia. Skin itching and allergic rash have been reported rarely.

There is not enough reliable safety data in pregnancy, so it is best to avoid unless your doctor advises otherwise. Safety while breastfeeding has not been well studied, so use caution and check with your doctor.

L-Carnitine is generally well tolerated at typical doses. Gastrointestinal upset — nausea, vomiting, diarrhea, heartburn, abdominal pain — and a fish-like body odor are the most common side effects.

There is not enough reliable safety data; use only under medical supervision. Safety while breastfeeding is rated Possibly Safe.

Magnesium is generally safe for healthy adults at recommended doses. The most common oral side effects are diarrhea, nausea, vomiting, and gastrointestinal irritation.

In pregnancy, magnesium is rated Likely Safe to Possibly Safe, but supplements should be used only under your doctor's guidance. Normal dietary amounts are appropriate while breastfeeding, but check with your doctor before using supplements.

Side effects, ingredient by ingredient Magnesium Coenzyme Q10 L-carnitine

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Coenzyme Q10, Magnesium, L-carnitine.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; heart-rhythm medications; Parkinson's medications.
  • For scale: 475 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check levodopa/carbidopa (Sinemet) for Parkinson's disease — magnesium can significantly reduce its effectiveness. Check blood thinners like warfarin, as both CoQ10 and L-Carnitine may affect how they work.

Verify thyroid hormone replacement (L-Carnitine may reduce its effect), blood pressure medications (CoQ10 may lower blood pressure further), skeletal muscle relaxants (magnesium strengthens their effect), diabetes medications (magnesium may raise the risk of low blood sugar), potassium-sparing water pills, calcium channel blockers, acid reducers, certain antibiotics, and osteoporosis drugs. No interactions are documented for the magnesium blend component itself.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.

This product is worth considering if you have CoQ10 deficiency, low magnesium, L-carnitine deficiency, or conditions like migraine, heart failure, or high cholesterol — but only if you're not on Sinemet, blood thinners, thyroid medication, or blood pressure drugs without checking first. If you take any prescription medications, run them through the medication checker on this page before starting.

A conversation with your pharmacist will help you sort out timing and whether this combination is right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 24, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about CoQ10 L-Carnitine Magnesium, straight from the product label.

Brand Doctor's Best
Barcode (UPC) 753950004771
Net contents 90 Veggie Cap(s)
Market status On market
Date entered into DSLD Sep 24, 2019
DSLD ID 203385
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for CoQ10 L-Carnitine Magnesium by Doctor's Best, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Veggie Capsule(s)
Maximum serving Sizes:
3 Veggie Capsule(s)
Servings per container
30
UPC/BARCODE
753950004771
IngredientAmount% DV
Magnesium200 mg50%
Coenzyme Q10200 mg--
L-Carnitine500 mg--
L-Carnitine Fumarate855 mg--
Magnesium Bisglycinate Chelate buffered1112 mg--

Other ingredients: Modified Cellulose, Microcrystalline Cellulose, Silicon Dioxide, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Doctor's Best combination of CoQ10, L-Carnitine, and buffered chelated Magnesium is a unique blend of nutrients that supports energy, muscle mass and muscle recovery. This convenient combination is designed to help support your high intensity workouts and optimize physical performance.

USP Verified, Naturally Fermented CoQ10

General Statements

Helps support energy Helps support muscle mass Helps support muscle recovery

Helps support energy, muscle mass and muscle recovery

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Brand IP Statement(s)

The Albion Gold Medallion design is a registered trademark of Albion Laboratories, Inc.

Science-Based Nutrition

General

YDRB477

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Albion Minerals

Vegan

Suggested/Recommended/Usage/Directions

Take 3 capsules daily with food, or as recommended by a nutritionally-informed physician.

Formulation

Non-GMO Gluten free Soy free

Vegan

Storage

Store in a cool dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

CoQ10 L-Carnitine Magnesium by Doctor's Best label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

CoQ10 L-Carnitine Magnesium label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in CoQ10 L-Carnitine Magnesium by Doctor's Best

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Veggie Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Magnesium

Interacts with
295 drugs
200 mg per serving

Magnesium is an essential mineral your body needs for muscles, nerves, blood pressure, and many other functions, and supplements are useful for preven...

Magnesium monograph & interactions

Coenzyme Q10

Interacts with
198 drugs
200 mg per serving Form: Ubiquinone

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...

Coenzyme Q10 monograph & interactions

L-Carnitine Fumarate

Interacts with
19 drugs
855 mg per serving

L-carnitine is a compound your body makes naturally and also gets from foods like meat. It helps cells turn fat into energy, and supplements are most...

L-Carnitine Fumarate monograph & interactions

Other (inactive) ingredients: Modified Cellulose, Microcrystalline Cellulose, Silicon Dioxide, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

CoQ10 L-Carnitine Magnesium by Doctor's Best Drug Interactions

Want to check YOUR meds against CoQ10 L-Carnitine Magnesium?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
475Drugs
6 Major 218 Moderate 251 Minor

Ingredients driving the most interactions

Magnesium 295
Coenzyme Q10 198
L-Carnitine Fumarate 19

Individual Drug Interactions

The ingredients in CoQ10 L-Carnitine Magnesium interact with 475 drugs. Click any drug to see the details.

3 of the 3 ingredients in CoQ10 L-Carnitine Magnesium interact with drugs. Each result below shows which ingredient is responsible. Magnesium Coenzyme Q10 L-Carnitine Fumarate

Each ingredient & the kinds of drugs it affects

For each ingredient in CoQ10 L-Carnitine Magnesium with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Magnesium15 drug types · 295 drugs

Levodopa/Carbidopa (Sinemet)

Magnesium can reduce the bioavailability of levodopa/carbidopa.
Clinical research in healthy volunteers shows that taking magnesium oxide 1000 mg with levodopa 100 mg/carbidopa 10 mg reduces the area under the curve (AUC) of levodopa by 35% and of carbidopa by 81%. In vitro and animal research shows that magnesium produces an alkaline environment in the digestive tract, which might lead to degradation and reduced bioavailability of levodopa/carbidopa.

Likelihood Probable Evidence B
Aminoglycoside Antibiotics

Concomitant use of aminoglycoside antibiotics and magnesium can increase the risk for neuromuscular weakness.
Both aminoglycosides and magnesium reduce presynaptic acetylcholine release, which can lead to neuromuscular blockade and possible paralysis. This is most likely to occur with high doses of magnesium given intravenously.

Likelihood Possible Evidence D
Antacids

Use of acid reducers may reduce the laxative effect of magnesium oxide.
A retrospective analysis shows that, in the presence of H2 receptor antagonists (H2RAs) or proton pump inhibitors (PPIs), a higher dose of magnesium oxide is needed for a laxative effect. This may also occur with antacids. Under acidic conditions, magnesium oxide is converted to magnesium chloride and then to magnesium bicarbonate, which has an osmotic laxative effect. By reducing acidity, antacids may reduce the conversion of magnesium oxide to the active bicarbonate salt.

Likelihood Possible Evidence D
Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)

Magnesium might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide should be taken at least 2 hours before or 6 hours after magnesium containing products.

Likelihood Probable Evidence D
Bisphosphonates

Magnesium can decrease absorption of bisphosphonates.
Cations, including magnesium, can decrease bisphosphonate absorption. Advise patients to separate doses of magnesium and these drugs by at least 2 hours.

Likelihood Probable Evidence B
Calcium Channel Blockers

Magnesium can have additive effects with calcium channel blockers, although evidence is conflicting.
Magnesium inhibits calcium entry into smooth muscle cells and may therefore have additive effects with calcium channel blockers. Severe hypotension and neuromuscular blockades may occur when nifedipine is used with intravenous magnesium, although some contradictory evidence suggests that concurrent use of magnesium with nifedipine does not increase the risk of neuromuscular weakness. High doses of magnesium could theoretically have additive effects with other calcium channel blockers.

Likelihood Possible Evidence D
Digoxin

Magnesium salts may reduce absorption of digoxin.
Clinical evidence suggests that treatment with oral magnesium hydroxide or magnesium trisilicate reduces absorption of digoxin from the intestines. This may reduce the blood levels of digoxin and decrease its therapeutic effects.

Likelihood Possible Evidence B
Potassium-Sparing Diuretics

Potassium-sparing diuretics decrease excretion of magnesium, possibly increasing magnesium levels.
Potassium-sparing diuretics also have magnesium-sparing properties, which can counteract the magnesium losses associated with loop and thiazide diuretics. Theoretically, increased magnesium levels could result from concomitant use of potassium-sparing diuretics and magnesium supplements.

Likelihood Probable Evidence D
Quinolone Antibiotics

Magnesium decreases absorption of quinolones.
Magnesium can form insoluble complexes with quinolones and decrease their absorption. Advise patients to take these drugs at least 2 hours before, or 4 to 6 hours after, magnesium supplements.

Likelihood Probable Evidence D
Skeletal Muscle Relaxants

Parenteral magnesium alters the pharmacokinetics of skeletal muscle relaxants, increasing their effects and accelerating the onset of effect.
Parenteral magnesium shortens the time to onset of skeletal muscle relaxants by about 1 minute and prolongs the duration of action by about 2 minutes. Magnesium potentiates the effects of skeletal muscle relaxants by decreasing calcium-mediated release of acetylcholine from presynaptic nerve terminals, reducing postsynaptic sensitivity to acetylcholine, and having a direct effect on the membrane potential of myocytes. Magnesium also has vasodilatory actions and increases cardiac output, allowing a greater amount of muscle relaxant to reach the motor end plate. A clinical study found that low-dose rocuronium (0.45 mg/kg), when given after administration of magnesium 30 mg/kg over 10 minutes, has an accelerated onset of effect, which matches the onset of effect seen with a full-dose rocuronium regimen (0.6 mg/kg). In another clinical study, onset times for rocuronium doses of 0.3, 0.6, and 1.2 mg/kg were 86, 76, and 50 seconds, respectively, when given alone, but were reduced to 66, 44, and 38 seconds, respectively, when the doses were given after a 15-minute infusion of magnesium sulfate 60 mg/kg. Giving intraoperative intravenous magnesium sulfate, 50 mg/kg loading dose followed by 15 mg/kg/hour, reduces the onset time of rocuronium, enhances its clinical effects, reduces the dose of intraoperative opiates, and prolongs the spontaneous recovery time. It does not affect the activity of subsequently administered neostigmine.

Likelihood Probable Evidence A
Sulfonylureas

Magnesium increases the systemic absorption of sulfonylureas, increasing their effects and side effects.
Clinical research shows that administration of magnesium hydroxide with glyburide increases glyburide absorption, increases maximal insulin response by 35-fold, and increases the risk of hypoglycemia, when compared with glyburide alone. A similar interaction occurs between magnesium hydroxide and glipizide. The mechanism of this effect appears to be related to the elevation of gastrointestinal pH by magnesium-based antacids, increasing solubility and enhancing absorption of sulfonylureas.

Likelihood Probable Evidence B
Tetracycline Antibiotics

Magnesium decreases absorption of tetracyclines.
Magnesium can form insoluble complexes with tetracyclines in the gut and decrease their absorption and antibacterial activity. Advise patients to take these drugs 1 hour before or 2 hours after magnesium supplements.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, magnesium may have antiplatelet effects, but the evidence is conflicting.
In vitro evidence shows that magnesium sulfate inhibits platelet aggregation, even at low concentrations. Some preliminary clinical evidence shows that infusion of magnesium sulfate increases bleeding time by 48% and reduces platelet activity. However, other clinical research shows that magnesium does not affect platelet aggregation, although inhibition of platelet-dependent thrombosis can occur.

Likelihood Unlikely Evidence B
Gabapentin (Neurontin)

Gabapentin absorption can be decreased by magnesium.
Clinical research shows that giving magnesium oxide orally along with gabapentin decreases the maximum plasma concentration of gabapentin by 33%, time to maximum concentration by 36%, and area under the curve by 43%. Advise patients to take gabapentin at least 2 hours before, or 4 to 6 hours after, magnesium supplements.

Likelihood Unlikely Evidence B
Sevelamer (Renagel, Renvela)

Sevelamer may increase serum magnesium levels.
In patients on hemodialysis, sevelamer use was associated with a 0.28 mg/dL increase in serum magnesium. The mechanism of this interaction remains unclear.

Likelihood Possible Evidence B
Magnesium full monograph & interactions

Coenzyme Q103 drug types · 198 drugs

Alkylating Agents

Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.

Likelihood Possible Evidence B
Coenzyme Q10 full monograph & interactions

L-Carnitine Fumarate3 drug types · 19 drugs

Acenocoumarol (Sintrom)

Theoretically, L-carnitine might increase the anticoagulant effects of acenocoumarol.
L-carnitine might enhance the anticoagulant effects of acenocoumarol, an oral anticoagulant similar to warfarin, but shorter-acting. There are at least two case reports of INR elevation with concomitant use. In one case, a 33-year-old male with a previously stable INR had an elevated INR of 4.65 after L-carnitine was started and continued for 10 weeks. INR normalized after discontinuation of the L-carnitine-containing product.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, L-carnitine might decrease the effectiveness of thyroid hormone replacement.
L-carnitine appears to act as a peripheral thyroid hormone antagonist by inhibiting entry of thyroid hormone into the nucleus of cells. Taking L-carnitine also seems to diminish some of the symptoms of hyperthyroidism.

Likelihood Probable Evidence B
Warfarin (Coumadin)

Theoretically, L-carnitine might increase the anticoagulant effects of warfarin.
L-carnitine might increase the anticoagulant effects of acenocoumarol, a shorter-acting oral anticoagulant similar to warfarin. There is not enough information to know whether this interaction occurs with L-carnitine and warfarin.

Likelihood Possible Evidence D
L-Carnitine Fumarate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for CoQ10 L-Carnitine Magnesium, from the product label.

Doctor's Best

See all Doctor's Best products
Name
Doctor's Best, Inc.
State
California
ZipCode
92612
Phone Number
(800) 777-2474
Web Address
www.drbvitamins.com
Pharmacist Counseling Corner

CoQ10 L-Carnitine Magnesium by Doctor's Best: Common Questions

Does CoQ10 L-Carnitine Magnesium by Doctor's Best interact with any medications?
Yes. Based on its ingredients, CoQ10 L-Carnitine Magnesium has a known interaction with 475 medications, including 6 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
CoQ10 L-Carnitine Magnesium contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is CoQ10 used for in this product?
CoQ10 is an energy molecule your cells naturally produce. In this product, it's included for conditions like heart health, migraine prevention, and fibromyalgia, though the evidence is strongest for CoQ10 deficiency itself.
Will this product lower my blood pressure?
CoQ10 may have minor blood-pressure-lowering effects based on some research, though results are mixed. If you're already on blood pressure medication, talk to your pharmacist before starting, since adding a minor effect could add up.
Can I take this while breastfeeding?
L-Carnitine is rated Possibly Safe while breastfeeding. CoQ10 safety hasn't been well studied during breastfeeding, so caution is advised. Magnesium at normal dietary amounts is fine, but check with your doctor before using the supplement form. It's best to talk with your doctor or pharmacist about the whole product.
What are the most common side effects?
Gastrointestinal upset — nausea, diarrhea, heartburn, abdominal discomfort — is most common across all three ingredients and occurs in a small percentage of users. L-Carnitine may also cause a fishy body odor, and magnesium at high doses can increase that effect.
Is this safe to take long-term?
CoQ10 and magnesium are generally well tolerated for long-term use at recommended doses. L-Carnitine should be used under medical supervision if you're taking it long-term. Any supplement taken indefinitely is worth discussing with your doctor, especially if you have a health condition.
Can I take this with my heart medication?
It depends on which heart drug you take. CoQ10 and L-Carnitine are actually used for some heart conditions and may be helpful, but both can interact with certain medications — including blood thinners and calcium channel blockers. Use the medication checker on this page to verify your specific drugs before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

CoQ10 L-Carnitine Magnesium label
Go deeper

The Full Monographs Behind CoQ10 L-Carnitine Magnesium’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Magnesium

Interacts with 295 drugs

Magnesium is an essential mineral your body needs for muscles, nerves, blood pressure, and many other functions, and supplements are useful for preventing or correcting deficiency. Some othe...

Read the full Magnesium monograph → Herb & supplement monograph

Coenzyme Q10

Interacts with 198 drugs

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated and is most studied for heart condition...

Read the full Coenzyme Q10 monograph → Herb & supplement monograph

L-carnitine

Interacts with 19 drugs

L-carnitine is a compound your body makes naturally and also gets from foods like meat. It helps cells turn fat into energy, and supplements are most clearly useful for people with a true ca...

Read the full L-carnitine monograph →
Sources

Sources & How We Checked

CoQ10 L-Carnitine Magnesium's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 163 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Magnesium 82 references
  1. Rodin SM, Johnson BF. Pharmacokinetic interactions with digoxin. Clin Pharmacokinet 1988;15:227-44.
  2. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  3. Dahle LO, Berg G, Hammar M, et al. The effect of oral magnesium substitution on pregnancy-induced leg cramps. Am J Obstet Gynecol 1995;173:175-80. PubMed
  4. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  5. Peikert A, Wilimzig C, Kohne-Volland R. Prophylaxis of migraine with oral magnesium: results from a prospective, multi-center, placebo-controlled and double-blind randomized study. Cephalalgia 1996;16:257-63. PubMed
  6. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Calcium, Phosphorus, Magnesium, Vitamin D, and Fluoride. Washington, DC: National Academy Press, 1999. Available at: http://books.nap.edu/books/0309063507/html/index.html.
  7. Birrer RB, Shallash AJ, Totten V. Hypermagnesemia-induced fatality following epsom salt gargles. J Emerg Med 2002;22:185-8. PubMed
  8. Ryan MP. Diuretics and potassium/magnesium depletion. Directions for treatment. Am J Med 1987;82:38-47.. PubMed
  9. Hollifield JW. Magnesium depletion, diuretics, and arrhythmias. Am J Med 1987;82:30-7.. PubMed
  10. Heidenreich O. Mode of action of conventional and potassium-sparing diuretics--aspects with relevance to Mg-sparing effects. Magnesium 1984;3:248-56..
  11. Pfaffenrath V, Wessely P, Meyer C, et al. Magnesium in the prophylaxis of migraine--a double-blind placebo-controlled study. Cephalalgia 1996;16:436-40.. PubMed
  12. Wang F, Van Den Eeden SK, Ackerson LM, et al. Oral magnesium oxide prophylaxis of frequent migrainous headache in children: a randomized, double-blind, placebo-controlled trial. Headache 2003;43:601-10.. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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