Cordychi Extract Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Cordychi Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Cordychi Extract is a dietary supplement by Host Defense Mushrooms with 3 active ingredients. Its ingredients are commonly taken for immune support, fatigue and general well-being, stress and sleep.Based on those ingredients, 502 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Reishi Mycelium Extract, Fresh, Cordyceps Mycelium Extract, Fresh. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Cordychi Extract by Host Defense Mushrooms
Ask about any prescription or over-the-counter medication and we check it for interactions with Cordychi Extract by Host Defense Mushrooms — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Cordychi Extract by Host Defense Mushrooms
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Cordychi Extract contains 3 active ingredients: two forms of reishi mushroom (mycelium and fruit body extracts, both fresh) and cordyceps mycelium extract. These are delivered in a liquid base of water and alcohol.
The proprietary blend format means the exact amount of each mushroom ingredient isn't broken out on the label.
Does it work?
Couldn't assess
The evidence for what this product actually works for isn't established in the data we hold. Reishi shows possibly ineffective ratings for cholesterol (hyperlipidemia), and insufficient evidence exists for altitude sickness, Alzheimer disease, and athletic performance.
Cordyceps is rated possibly ineffective for athletic performance and has insufficient evidence for sexual function, heart rhythm, asthma, lung cancer, and chronic obstructive pulmonary disease. In other words, we don't have reliable evidence that either ingredient delivers the effects people often seek.
How safe is it?
Well-documented data
Both reishi extracts are generally well tolerated short-term, though long-term safety isn't well studied. Common side effects include dizziness, dry mouth, itching, nausea, rash, and stomach upset.
Some people report sore throat, runny nose, insomnia, or headache. Respiratory allergy to reishi spores is possible.
Cordyceps is also generally well tolerated when used up to a year, with abdominal discomfort, constipation, diarrhea, and dry mouth being the most common effects — and these often improve if you take it after eating. One case report linked a cordyceps product to liver inflammation (cholestatic hepatitis), though it's unclear whether cordyceps itself or a contaminant caused it.
There isn't enough safety data to know whether reishi or cordyceps is safe during pregnancy or breastfeeding. The safety data advises against both during pregnancy and lactation.
Talk with your doctor or pharmacist about whether this product is right for you if you're pregnant or nursing.
Meds to double-check
Moderate interaction found
Check with your doctor or pharmacist before using this product if you take blood pressure medications, blood thinners or antiplatelet drugs, blood sugar medications, immune-suppressing drugs, or testosterone. These are the main medication categories where interactions have been documented for the reishi and cordyceps in this product.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Cordychi Extract is a liquid mushroom blend with documented interactions primarily affecting blood pressure, blood-thinning, blood sugar, immune, and testosterone medications. We don't have evidence in our data that either ingredient works for its commonly claimed uses.
It's generally well tolerated short-term for most people, but long-term safety isn't clear. If you take any medications, run them through the interaction checker on this page, and talk with your doctor or pharmacist before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Cordychi Extract, straight from the product label.
| Brand | Host Defense Mushrooms |
|---|---|
| Net contents | 2 Fluid Ounce(s); 60 mL |
| Market status | On market |
| Date entered into DSLD | Jul 25, 2024 |
| DSLD ID | 312391 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Organic, Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Cordychi Extract by Host Defense Mushrooms, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Extract Blend | 1 mL | -- |
| Reishi Mycelium Extract, Fresh | 0 NP | -- |
| Reishi Fruit body Extract, Dried | 0 NP | -- |
| Cordyceps Mycelium Extract, Fresh | 0 NP | -- |
Other ingredients: Water, Alcohol
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: Take 1 full dropper bulb squeeze (1 mL) twice per day.
Precautions
Caution: If you have a medical condition, are taking medications, or are pregnant or breastfeeding, consult a healthcare professional before using this product.
Keep out of reach of children.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Formula
Superfood mushroom mycelium
Formulation
Non GMO Gluten free
Supports stress & fatigue reduction
Certified organic by the WSDA
Seals/Symbols
USDA Organic
Certified Organic Washington State Department of Agriculture Organic Program
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Cordychi Extract by Host Defense Mushrooms label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Cordychi Extract by Host Defense Mushrooms
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Extract Blend
Other (inactive) ingredients: Water, Alcohol. These complete the product’s ingredient list but are not active constituents.
Cordychi Extract by Host Defense Mushrooms Drug Interactions
HelloPharmacist Interaction Report
Cordychi Extract by Host Defense Mushrooms interacts with medications through its reishi and cordyceps content.
The most serious interactions are Moderate in severity and span three major drug categories.
Read the full breakdown — every affected drug type, severity by severity
Both reishi extracts in this product may increase the risk of low blood pressure (hypotension) when combined with blood pressure medications (antihypertensive drugs). Reishi has shown blood-pressure-lowering activity in animal studies and some clinical evidence supports this effect, though it doesn't work in everyone.
All three active ingredients — the two reishi extracts and cordyceps — interact with blood thinners and antiplatelet drugs (anticoagulant/antiplatelet drugs). At higher doses, reishi mushroom may increase bleeding risk; cordyceps theoretically poses a similar risk, though this hasn't been reported in humans yet.
Reishi may also work additively with blood sugar medications (antidiabetes drugs), and cordyceps theoretically may interfere with immune-suppressing medications (immunosuppressants). Cordyceps also carries a Minor interaction with testosterone — theoretically additive, though the clinical significance is unclear.
Altogether, these interactions span 502 individual medications. If you take any blood pressure medication, blood thinner, diabetes medication, immunosuppressant, or testosterone supplement, check your exact medications with the search tool on this page before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Cordychi Extract?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Cordychi Extract interact with 502 drugs. Click any drug to see the details.
2 of the 3 ingredients in Cordychi Extract interact with drugs. Each result below shows which ingredient is responsible. Reishi Mycelium Extract, Fresh Cordyceps Mycelium Extract, Fresh
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Cordychi Extract — through 1 ingredient. Tap an ingredient for the detail:
Cordyceps Mycelium Extract, FreshImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Read the full Cordyceps Mycelium Extract, Fresh + 6-mercaptopurine interactionAbciximabReoPro
How Abciximab interacts with Cordychi Extract — through 2 ingredients. Tap an ingredient for the detail:
Cordyceps Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Cordyceps Mycelium Extract, Fresh + Abciximab interactionReishi Fruit Body Extract, DriedAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Fruit Body Extract, Dried + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Cordychi Extract — through 2 ingredients. Tap an ingredient for the detail:
Reishi Fruit Body Extract, DriedAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Fruit Body Extract, Dried + Abrocitinib interactionCordyceps Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs, Immunosuppressants Moderate
Interaction Summary
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Cordyceps Mycelium Extract, Fresh + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Cordychi Extract — through 1 ingredient. Tap an ingredient for the detail:
Reishi Fruit Body Extract, DriedAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Read the full Reishi Fruit Body Extract, Dried + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Cordychi Extract — through 1 ingredient. Tap an ingredient for the detail:
Reishi Fruit Body Extract, DriedAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Reishi Fruit Body Extract, Dried + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Cordychi Extract — through 2 ingredients. Tap an ingredient for the detail:
Reishi Fruit Body Extract, DriedAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Fruit Body Extract, Dried + Acenocoumarol interactionCordyceps Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Cordyceps Mycelium Extract, Fresh + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Cordychi Extract — through 2 ingredients. Tap an ingredient for the detail:
Cordyceps Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Cordyceps Mycelium Extract, Fresh + Acetaminophen, Aspirin interactionReishi Fruit Body Extract, DriedAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Fruit Body Extract, Dried + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Cordychi Extract — through 2 ingredients. Tap an ingredient for the detail:
Reishi Fruit Body Extract, DriedAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Fruit Body Extract, Dried + Acetaminophen, Aspirin, Caffeine interactionCordyceps Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Cordyceps Mycelium Extract, Fresh + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Cordychi Extract — through 2 ingredients. Tap an ingredient for the detail:
Cordyceps Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Cordyceps Mycelium Extract, Fresh + Acetaminophen, Ibuprofen interactionReishi Fruit Body Extract, DriedAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Fruit Body Extract, Dried + Acetaminophen, Ibuprofen interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Cordychi Extract — through 1 ingredient. Tap an ingredient for the detail:
Reishi Fruit Body Extract, DriedAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Reishi Fruit Body Extract, Dried + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Cordychi Extract — through 1 ingredient. Tap an ingredient for the detail:
Reishi Fruit Body Extract, DriedAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Read the full Reishi Fruit Body Extract, Dried + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Cordychi Extract — through 2 ingredients. Tap an ingredient for the detail:
Reishi Fruit Body Extract, DriedAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Fruit Body Extract, Dried + Acetylsalicylic Acid interactionCordyceps Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Cordyceps Mycelium Extract, Fresh + Acetylsalicylic Acid interactionAdalimumabHumira
How Adalimumab interacts with Cordychi Extract — through 1 ingredient. Tap an ingredient for the detail:
Cordyceps Mycelium Extract, FreshImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Read the full Cordyceps Mycelium Extract, Fresh + Adalimumab interactionAdalimumab-adazHyrimoz
How Adalimumab-adaz interacts with Cordychi Extract — through 1 ingredient. Tap an ingredient for the detail:
Cordyceps Mycelium Extract, FreshImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Read the full Cordyceps Mycelium Extract, Fresh + Adalimumab-adaz interactionAdalimumab-adbmCyltezo
How Adalimumab-adbm interacts with Cordychi Extract — through 1 ingredient. Tap an ingredient for the detail:
Cordyceps Mycelium Extract, FreshImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Read the full Cordyceps Mycelium Extract, Fresh + Adalimumab-adbm interactionAdalimumab-afzbAbrilada
How Adalimumab-afzb interacts with Cordychi Extract — through 1 ingredient. Tap an ingredient for the detail:
Cordyceps Mycelium Extract, FreshImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Read the full Cordyceps Mycelium Extract, Fresh + Adalimumab-afzb interactionAdalimumab-attoAmjevita
How Adalimumab-atto interacts with Cordychi Extract — through 1 ingredient. Tap an ingredient for the detail:
Cordyceps Mycelium Extract, FreshImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Read the full Cordyceps Mycelium Extract, Fresh + Adalimumab-atto interactionAdalimumab-bwwdHadlima
How Adalimumab-bwwd interacts with Cordychi Extract — through 1 ingredient. Tap an ingredient for the detail:
Cordyceps Mycelium Extract, FreshImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Read the full Cordyceps Mycelium Extract, Fresh + Adalimumab-bwwd interactionAdalimumab-fkjpHulio
How Adalimumab-fkjp interacts with Cordychi Extract — through 1 ingredient. Tap an ingredient for the detail:
Cordyceps Mycelium Extract, FreshImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Read the full Cordyceps Mycelium Extract, Fresh + Adalimumab-fkjp interactionAlbiglutideTanzeum
How Albiglutide interacts with Cordychi Extract — through 1 ingredient. Tap an ingredient for the detail:
Reishi Fruit Body Extract, DriedAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Read the full Reishi Fruit Body Extract, Dried + Albiglutide interactionAlefaceptAmevive
How Alefacept interacts with Cordychi Extract — through 1 ingredient. Tap an ingredient for the detail:
Cordyceps Mycelium Extract, FreshImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Read the full Cordyceps Mycelium Extract, Fresh + Alefacept interactionAlemtuzumabCampath
How Alemtuzumab interacts with Cordychi Extract — through 1 ingredient. Tap an ingredient for the detail:
Cordyceps Mycelium Extract, FreshImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Read the full Cordyceps Mycelium Extract, Fresh + Alemtuzumab interactionAliskirenTekturna
How Aliskiren interacts with Cordychi Extract — through 1 ingredient. Tap an ingredient for the detail:
Reishi Fruit Body Extract, DriedAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Reishi Fruit Body Extract, Dried + Aliskiren interactionAlogliptinNesina
How Alogliptin interacts with Cordychi Extract — through 1 ingredient. Tap an ingredient for the detail:
Reishi Fruit Body Extract, DriedAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Read the full Reishi Fruit Body Extract, Dried + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Cordychi Extract — through 1 ingredient. Tap an ingredient for the detail:
Reishi Fruit Body Extract, DriedAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Read the full Reishi Fruit Body Extract, Dried + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Cordychi Extract — through 1 ingredient. Tap an ingredient for the detail:
Reishi Fruit Body Extract, DriedAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Read the full Reishi Fruit Body Extract, Dried + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Cordychi Extract — through 2 ingredients. Tap an ingredient for the detail:
Reishi Fruit Body Extract, DriedAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Fruit Body Extract, Dried + Alteplase, Tpa interactionCordyceps Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Cordyceps Mycelium Extract, Fresh + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Cordychi Extract — through 2 ingredients. Tap an ingredient for the detail:
Cordyceps Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Cordyceps Mycelium Extract, Fresh + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionReishi Fruit Body Extract, DriedAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Fruit Body Extract, Dried + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Cordychi Extract — through 2 ingredients. Tap an ingredient for the detail:
Cordyceps Mycelium Extract, FreshAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Cordyceps Mycelium Extract, Fresh + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionReishi Fruit Body Extract, DriedAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
Read the full Reishi Fruit Body Extract, Dried + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Cordychi Extract — through 1 ingredient. Tap an ingredient for the detail:
Reishi Fruit Body Extract, DriedAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Read the full Reishi Fruit Body Extract, Dried + Ambrisentan interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Cordychi Extract with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Reishi Mycelium Extract, Fresh
Anticoagulant/Antiplatelet Drugs
Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
A dose of 1.5 grams daily of reishi mushroom does not seem to decrease platelet aggregation, but a higher dose of 3 grams daily does.
Antidiabetes Drugs
Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Animal research suggests that reishi mushroom decreases blood sugar. However, in patients with type 2 diabetes, taking reishi mushroom does not reduce fasting glucose levels, and its effects on glycated hemoglobin are inconsistent.
Antihypertensive Drugs
Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Reishi mushroom has shown hypotensive activity in animal research. Clinical evidence suggests that reishi mushroom reduces blood pressure in some, but not all, patients with hypertension.
Cordyceps Mycelium Extract, Fresh
Anticoagulant/Antiplatelet Drugs
Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
In vitro and animal research suggests that cordyceps extract inhibits platelet aggregation and function. However, this interaction has not been reported in humans.
Immunosuppressants
Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Animal and in vitro research suggests that cordyceps stimulates the immune system. However, limited clinical research suggests that taking cordyceps may lower the necessary therapeutic dose of the immunosuppressant cyclosporine, which suggests that cordyceps may have an immunosuppressive effect.
Testosterone
Theoretically, concurrent use of cordyceps and testosterone might have additive effects.
Animal research suggests that cordyceps can increase testosterone levels. The clinical significance of this finding is unclear.
Brand information
Manufacturer and brand details for Cordychi Extract, from the product label.
Host Defense Mushrooms
See all Host Defense Mushrooms products- Name
- Fungi Perfecti, LLC
- Street Address
- PO Box 7634
- City
- Olympia
- State
- WA
- ZipCode
- 98507
- Phone Number
- 877-504-6926
- Web Address
- Hostdefense.com
Cordychi Extract by Host Defense Mushrooms: Common Questions
Does Cordychi Extract by Host Defense Mushrooms interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take Cordychi Extract if I'm pregnant or nursing?
What are the most common side effects?
How long is this product safe to use?
Does this product actually work for athletic performance?
Can I take this if I'm on blood thinners?
What's in the bottle besides the mushroom extracts?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Cordychi Extract is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Cordychi Extract’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Reishi Mushroom
Interacts with 375 drugsReishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits is limited or low-quality, so it should...
Read the full Reishi Mushroom monograph → Herb & supplement monographCordyceps
Interacts with 249 drugsCordyceps is a fungus used in traditional Chinese medicine for energy, exercise performance, and lung and immune support. Human research is limited and mostly low quality, so its benefits ar...
Read the full Cordyceps monograph →Sources & How We Checked
Cordychi Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 31 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Reishi Mushroom 17 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Tao J, Feng KY. Experimental and clinical studies on inhibitory effect of ganoderma lucidum on platelet aggregation. J Tongji Med Univ 1990;10:240-3. PubMed
- Singh AB, Gupta SK, Pereira BM, Prakash D. Sensitization to Ganoderma lucidum in patients with respiratory allergy in India. Clin Exp Allergy 1995;25:440-7.
- Lee SY, Rhee HM. Cardiovascular effects of mycelium extract of Ganoderma lucidum: inhibition of sympathetic outflow as a mechanism of its hypotensive action. Chem Pharm Bull (Tokyo) 1990;38:1359-64. PubMed
- Kwok Y, Ng KFJ, Li, CCF, et al. A prospective, randomized, double-blind, placebo-controlled study of the platelet and global hemostatic effects of Ganoderma lucidum (Ling-Zhi) in healthy volunteers. Anesth Analg 2005;101:423-6. PubMed
- Wanmuang, H., Leopairut, J., Kositchaiwat, C., Wananukul, W., and Bunyaratvej, S. Fatal fulminant hepatitis associated with Ganoderma lucidum (Lingzhi) mushroom powder. J Med Assoc Thai. 2007;90(1):179-181.
- Seto, S. W., Lam, T. Y., Tam, H. L., Au, A. L., Chan, S. W., Wu, J. H., Yu, P. H., Leung, G. P., Ngai, S. M., Yeung, J. H., Leung, P. S., Lee, S. M., and Kwan, Y. W. Novel hypoglycemic effects of Ganoderma lucidum water-extract in obese/diabetic (+db/+db
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