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Dietary supplement

Cracked Cell Chlorella Ingredients & Drug Interactions

by Purium

Tablet Or Pill Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Cracked Cell Chlorella is a dietary supplement by Purium with 1 active ingredient. Its ingredients are commonly taken for general nutrition and 'detox' support, immune support, liver and kidney support.Based on those ingredients, 337 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Chlorella. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Cracked Cell Chlorella by Purium

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Cracked Cell Chlorella contains one active ingredient: chlorella, a freshwater algae. It's a whole-food supplement, meaning you're getting the algae itself rather than an isolated compound.

The product has no inactive fillers or binders listed.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Chlorella's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: cellular cleanse and detoxification support.
  • We looked for evidence on: Nonalcoholic fatty liver disease (NAFLD), Hepatitis C, Hyperlipidemia, Metabolic syndrome, heavy metal detoxification, general detoxification — and 1 related terms.
  • The closest evidence on file: Chlorella is rated "Insufficient Reliable Evidence To Rate" for Nonalcoholic fatty liver disease (NAFLD) (Natural Medicines).
  • Also on file: Chlorella is rated "Insufficient Reliable Evidence To Rate" for Hepatitis C, Hyperlipidemia, Metabolic syndrome.

The evidence for chlorella is mixed. It's possibly effective for pregnancy-related iron deficiency, but that's the strongest claim we have.

For brain tumors, fatty liver disease, depression, and fatigue, the evidence we hold is insufficient to rate whether it works or not. If you're considering this for any of those uses, talk with your doctor about what the current research shows.

The evidence, ingredient by ingredient Chlorella

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Chlorella is generally well tolerated when taken short-term, but quality and purity vary widely between products, so choose carefully. The most common side effects are allergic reactions, stomach cramping, constipation, diarrhea, fatigue, gas, nausea, and photosensitivity (sun sensitivity)—especially in the first two weeks.

Rare but serious allergic reactions, including anaphylaxis, have been reported. There isn't enough safety data to know how safe this product is during pregnancy or breastfeeding, so talk with your doctor or pharmacist before using it if you're pregnant, planning to become pregnant, or breastfeeding.

Side effects, ingredient by ingredient Chlorella

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Chlorella.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 337 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with us before taking this if you're on warfarin or another blood thinner (Moderate severity)—chlorella's vitamin K content can reduce how well they work. Also double-check if you take photosensitizing drugs that make your skin more sun-sensitive (Moderate severity).

Use the search tool on this page with your exact medication names.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Chlorella might help with pregnancy-related iron deficiency, but the evidence for other uses is unclear. The main thing to watch is whether you take blood thinners or photosensitizing medications—both can be affected.

Talk with your pharmacist before starting, especially if you take warfarin or any prescription drugs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cracked Cell Chlorella, straight from the product label.

Brand Purium
Barcode (UPC) 764934024838
Net contents 480 Tablet(s)
Market status On market
Date entered into DSLD Sep 25, 2024
DSLD ID 313752
Product type Botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cracked Cell Chlorella by Purium, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
12 Tablet(s)
Maximum serving Sizes:
12 Tablet(s)
Servings per container
40
UPC/BARCODE
764934024838
IngredientAmount% DV
Chlorella3 Gram(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Peel back for more info The transformation company

Pure + Premium = Purium Co-founders Amy Venner and Dave Sandoval are passionate about making the world a better place. With over 60 years combined experience, they provide the highest quality superfood nutrition while practicing commerce with a conscience and serving their community.

The quality of food you eat is equal to the quality of life you live. Learn more about Purium

Compostable Materials meet ASTM D6400 standards. Committed to freeing our planet from plastic pollution! Remove and discard the label prior to composting.

Formulation

Cellular cleanse

Vegan & gluten-free

Vegan & gluten-free

USDA Organic Quality Assurance International Certified Organic If it's Organic It's Non-GMO

If it's Organic It's Non-GMO

Their dedication safeguards Purium's commitment to provide pure and premium superfoods; grown, manufactured and tested to the highest standards. From farm to family, Purium delivers the finest nutrition with the lowest possible environmental impact.

Cracked Cell Chlorella is Certified Organic by QAI.

Seals/Symbols

USDA Organic Quality Assurance International Certified Organic If it's Organic It's Non-GMO

OK (Kosher)

Suggested/Recommended/Usage/Directions

Suggested use: Take 12 tablets per day. Can be taken with or without food.

Precautions

Caution: Keep out of reach of children.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

OK (Kosher)

See for yourself

Cracked Cell Chlorella by Purium label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Cracked Cell Chlorella by Purium

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size12 Tablet(s) Dosage formTablet Or Pill Servings per container40 Amounts shown are per serving.

Chlorella

Interacts with
337 drugs
3 Gram(s) per serving

Chlorella is a nutrient-rich freshwater green algae taken as a supplement for general wellness, immune support, and 'detox.' Some small studies sugges...

Chlorella monograph & interactions
Interaction report

Cracked Cell Chlorella by Purium Drug Interactions

Want to check YOUR meds against Cracked Cell Chlorella?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
337Drugs
337 Moderate

Ingredients driving the most interactions

Chlorella 337

Each ingredient & the kinds of drugs it affects

For each ingredient in Cracked Cell Chlorella with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Chlorella2 drug types · 337 drugs

Photosensitizing Drugs

Theoretically, chlorella might have additive effects with photosensitizing drugs.
Chlorella has been reported to cause photosensitization. In five case reports, patients who had ingested chlorella exhibited swelling followed by erythematopurpuric lesions on sun-exposed areas of the body. Theoretically, concomitant use with photosensitizing drugs may exacerbate effects.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, chlorella might reduce the clinical effects of warfarin.
Chlorella contains significant amounts of vitamin K. There is at least one case report of warfarin therapy becoming sub-therapeutic after initiation of chlorella supplements.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Cracked Cell Chlorella, from the product label.

Purium

See all Purium products
Name
Purium
Street Address
2610 Homestead Place
City
Rancho Dominguez
State
CA
ZipCode
90220
Phone Number
1-888-747-6733
Web Address
ishoppurium.com
Pharmacist Counseling Corner

Cracked Cell Chlorella by Purium: Common Questions

Does Cracked Cell Chlorella by Purium interact with any medications?
Yes. Based on its ingredients, Cracked Cell Chlorella has a known interaction with 337 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Cracked Cell Chlorella contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What's in Cracked Cell Chlorella?
It's just one ingredient: chlorella, a freshwater algae, with no added fillers or binders. The "cracked cell" refers to how the algae's cell wall is processed to make it easier for your body to absorb.
Will it give me more energy?
Energy and fatigue are listed uses, but we don't have enough reliable evidence to say whether chlorella actually works for that. If you try it and feel better, that's great—but don't count on it based on the research we hold.
Can I take this if I'm pregnant?
There isn't enough safety data to know either way. Talk with your doctor or pharmacist for personalized advice before using it during pregnancy or breastfeeding.
What side effects might I get?
The most common ones are stomach cramping, diarrhea, constipation, nausea, gas, fatigue, and—importantly—photosensitivity, which means your skin becomes more sensitive to sunburn. Allergic reactions, including serious ones, have been reported too. These are usually mild, especially in the first two weeks.
Why does quality vary?
Chlorella products differ in purity and what contaminants they may contain. That's why we recommend checking the manufacturer's third-party testing or quality certifications before you buy.
Will this interfere with my warfarin?
Chlorella is high in vitamin K, which works against warfarin. There's a case report of someone's warfarin therapy becoming ineffective after starting chlorella. If you take warfarin or any blood thinner, do not start this without checking with your pharmacist first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Cracked Cell Chlorella is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cracked Cell Chlorella label
Go deeper

The Full Monographs Behind Cracked Cell Chlorella’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Cracked Cell Chlorella's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 13 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Chlorella 13 references
  1. Peirce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York, NY: William Morrow and Co., 1999.
  2. Ng TP, Tan WC, Lee YK. Occupational asthma in a pharmacist induced by chlorella, a unicellular algae preparation. Resp Med 1994;88:555-7. PubMed
  3. Jitsukawa K, Suizu R, Hidano A. Chlorella photosensitization. New phytophotodermatosis. Int J Dermatol 1984;23:263-8. PubMed
  4. Merchant RE, Carmack CA, Wise CM. Nutritional supplementation with Chlorella pyrenoidosa for patients with fibromyalgia syndrome: a pilot study. Phytother Res 2000;14:167-73.
  5. Merchant RE, Rice CD, Young HF. Dietary Chlorella pyrenoidosa for patients with malignant glioma: effects on immunocompetence, quality of life, and survival. Phytother Res 1990;4:220-31.
  6. Halperin SA, Smith B, Nolan C, et al. Safety and immunoenhancing effect of a Chlorella-derived dietary supplement in healthy adults undergoing influenza vaccination: randomized, double-blind, placebo-controlled trial. CMAJ 2003;169:111-7..
  7. Ohtake, T., Negishi, K., Okamoto, K., Oka, M., Maesato, K., Moriya, H., and Kobayashi, S. Manganese-induced Parkinsonism in a patient undergoing maintenance hemodialysis. Am J Kidney Dis 2005;46(4):749-753. PubMed
  8. Ng, T. P., Tan, W. C., and Lee, Y. K. Occupational asthma in a pharmacist induced by Chlorella, a unicellular algae preparation. Respir.Med. 1994;88(7):555-557. PubMed
  9. Ohkawa, S., Yoneda, Y., Ohsumi, Y., and Tabuchi, M. [Warfarin therapy and chlorella]. Rinsho Shinkeigaku 1995;35(7):806-807.
  10. Azocar J, Diaz A. Efficacy and safety of chlorella supplementation in adults with chronic hepatitis C virus infection. World J Gastroenterol 2013;19(7):1085-90. PubMed
  11. Panahi Y, Badeli R, Karami GR, Badeli Z, Sahebkar A. A randomized controlled trial of 6-week Chlorella vulgaris supplementation in patients with major depressive disorder. Complement Ther Med 2015;23(4):598-602. PubMed
  12. Nakano S, Takekoshi H, Nakano M. Chlorella pyrenoidosa supplementation reduces the risk of anemia, proteinuria and edema in pregnant women. Plant Foods Hum Nutr 2010;65(1):25-30. PubMed
  13. Yavasoglu I, Turgutkaya A, Bolaman Z. Chlorella-induced thrombocytopenia. Sao Paulo Med J 2018;136(6):602-3. PubMed

See these in context on the Chlorella monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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