Culver's Root (Blackroot) Ingredients & Drug Interactions
by Pure Herbs
What is this page for?
First and foremost: checking Culver's Root (Blackroot) against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Culver's Root (Blackroot) is a dietary supplement by Pure Herbs with 1 active ingredient. Its ingredients are commonly taken for constipation, liver and gallbladder complaints, digestive upset.Based on those ingredients, 78 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Culver's Root Root Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Culver's Root (Blackroot) by Pure Herbs
Ask about any prescription or over-the-counter medication and we check it for interactions with Culver's Root (Blackroot) by Pure Herbs — and tell you which ingredient is responsible.
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HelloPharmacist Scorecard of Culver's Root (Blackroot) by Pure Herbs
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This liquid contains one active ingredient: Culver's Root Root Extract, also known as black root. There are no inactive ingredients listed.
Does it work?
Couldn't assess
No effectiveness ratings are on file for Culver's Root in the data we hold, so we can't tell you how well it works for any particular purpose.
How safe is it?
Well-documented data
Modern safety data for black root are limited, and the fresh root can cause significant digestive upset. The supplement can trigger abdominal pain or cramps, changes in stool color or odor, drowsiness, headache, nausea, and vomiting.
Large amounts have been linked to liver toxicity (hepatotoxicity). Culver's Root is rated possibly unsafe in pregnancy because of its strong laxative effect and lack of safety data — the facts advise against it during pregnancy.
It's also rated unsafe while breastfeeding due to insufficient safety information, so talk with your doctor or pharmacist before using it if you're nursing.
Meds to double-check
Moderate interaction found
Before taking this product, double-check it with your pharmacist or doctor if you take warfarin (Coumadin) or any blood thinner, a heart medication like digoxin (Lanoxin), or any diuretic (water pill). These are the main medication types with documented interactions with black root.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Culver's Root is a strong laxative supplement with notable interactions, especially with blood thinners, heart drugs, and diuretics. If you take any prescription medications — particularly warfarin, digoxin, or water pills — check with your pharmacist before starting this product.
Pregnant or breastfeeding? This one isn't recommended.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 13, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Culver's Root (Blackroot), straight from the product label.
| Brand | Pure Herbs |
|---|---|
| Net contents | 1 Fluid Ounce(s); 30 mL |
| Market status | On market |
| Date entered into DSLD | Dec 13, 2022 |
| DSLD ID | 278886 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Culver's Root (Blackroot) by Pure Herbs, sourced from the NIH Dietary Supplement Label Database.
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: For adults, mix 2 mL (abt. 1/2 tsp) of extract in 2 fl. oz (60 mL) water one time daily preferably with a meal.
Shake well before use
Formulation
Beneficial for digestion and liver health. Contributes to a healthy glucose metabolism and helps to maintain a healthy blood pressure already within the normal range.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Precautions
Warning: Not intended for use by pregnant or nursing women. If you have a medical condition or are taking medication, consult your doctor prior to use.
Discontinue use and consult with your doctor if any adverse reactions occur.
Keep out of reach of children
Brand IP Statement(s)
Pure Herbs, Ltd. Natural Herbal Extracts
FDA Statement of Identity
Dietary Supplement
General Statements
"No expense has been spared to provide the finest nature has to offer."
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Culver's Root (Blackroot) by Pure Herbs label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Culver's Root (Blackroot) by Pure Herbs
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 mL Dosage formLiquid Servings per container15 Amounts shown are per serving.
Culver's Root Root Extract
Interacts with78 drugs
Black Root is a traditional North American herb that was historically used as a strong laxative and to support digestion and liver function. There is...
Culver's Root Root Extract monograph & interactionsOther (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.
Culver's Root (Blackroot) by Pure Herbs Drug Interactions
HelloPharmacist Interaction Report
Culver's Root by Pure Herbs does interact with medications — mainly blood thinners, heart drugs, and water pills.
The most serious concern is with diuretics (water pills): black root has strong laxative effects and can cause diarrhea, which compounds potassium loss from certain diuretics and raises the risk of low potassium (hypokalemia). Some people taking potassium-depleting diuretics may need potassium supplementation or a dose increase.
Read the full breakdown — every affected drug type, severity by severity
Warfarin (Coumadin), a blood thinner, is a Major concern as well. The diarrhea from black root can increase warfarin's blood-thinning effect, raise your INR (a measure of how thin your blood is), and increase bleeding risk — so don't take large amounts if you're on warfarin.
Digoxin (Lanoxin), a heart medication, also carries Moderate risk. Overuse of black root can bind with digoxin in your stomach and reduce how well it works, while also raising the chance of side effects from the drug itself.
Altogether, these interactions span 78 individual medications. Use the medication checker below to look up any of your prescriptions before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Culver's Root (Blackroot)?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Culver's Root (Blackroot) interact with 78 drugs. Click any drug to see the details.
1 of the 1 ingredient in Culver's Root (Blackroot) interact with drugs. Each result below shows which ingredient is responsible. Culver's Root Root Extract
Acetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Culver's Root (Blackroot) — through 1 ingredient. Tap an ingredient for the detail:
Culver's Root Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Culver's Root Root Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with Culver's Root (Blackroot) — through 1 ingredient. Tap an ingredient for the detail:
Culver's Root Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Culver's Root Root Extract + Acetaminophen, Pamabrom, Pyrilamine interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Culver's Root (Blackroot) — through 1 ingredient. Tap an ingredient for the detail:
Culver's Root Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Culver's Root Root Extract + Acetazolamide interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Culver's Root (Blackroot) — through 1 ingredient. Tap an ingredient for the detail:
Culver's Root Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Culver's Root Root Extract + Amiloride, Hydrochlorothiazide interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Culver's Root (Blackroot) — through 1 ingredient. Tap an ingredient for the detail:
Culver's Root Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Culver's Root Root Extract + Ammonium Chloride interactionAtenolol, ChlortalidoneAtenixCo, Tenoret 50, Totaretic
How Atenolol, Chlortalidone interacts with Culver's Root (Blackroot) — through 1 ingredient. Tap an ingredient for the detail:
Culver's Root Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Culver's Root Root Extract + Atenolol, Chlortalidone interactionAtenolol, ChlorthalidoneTenoretic
How Atenolol, Chlorthalidone interacts with Culver's Root (Blackroot) — through 1 ingredient. Tap an ingredient for the detail:
Culver's Root Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Culver's Root Root Extract + Atenolol, Chlorthalidone interactionAzilsartan, ChlorthalidoneEdarbyclor
How Azilsartan, Chlorthalidone interacts with Culver's Root (Blackroot) — through 1 ingredient. Tap an ingredient for the detail:
Culver's Root Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Culver's Root Root Extract + Azilsartan, Chlorthalidone interactionBenazepril, HydrochlorothiazideLotensin HCT
How Benazepril, Hydrochlorothiazide interacts with Culver's Root (Blackroot) — through 1 ingredient. Tap an ingredient for the detail:
Culver's Root Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Culver's Root Root Extract + Benazepril, Hydrochlorothiazide interactionBendroflumethiazideAprinox, Naturetin, Neo-NaClex
How Bendroflumethiazide interacts with Culver's Root (Blackroot) — through 1 ingredient. Tap an ingredient for the detail:
Culver's Root Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Culver's Root Root Extract + Bendroflumethiazide interactionBendroflumethiazide, NadololCorzide
How Bendroflumethiazide, Nadolol interacts with Culver's Root (Blackroot) — through 1 ingredient. Tap an ingredient for the detail:
Culver's Root Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Culver's Root Root Extract + Bendroflumethiazide, Nadolol interactionBendroflumethiazide, PotassiumCentyl K, Neo-NaClex-K
How Bendroflumethiazide, Potassium interacts with Culver's Root (Blackroot) — through 1 ingredient. Tap an ingredient for the detail:
Culver's Root Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Culver's Root Root Extract + Bendroflumethiazide, Potassium interactionBendroflumethiazide, Rauwolfia SerpentinaRauzide
How Bendroflumethiazide, Rauwolfia Serpentina interacts with Culver's Root (Blackroot) — through 1 ingredient. Tap an ingredient for the detail:
Culver's Root Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Culver's Root Root Extract + Bendroflumethiazide, Rauwolfia Serpentina interactionBenzthiazideExna
How Benzthiazide interacts with Culver's Root (Blackroot) — through 1 ingredient. Tap an ingredient for the detail:
Culver's Root Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Culver's Root Root Extract + Benzthiazide interactionBisoprolol, HydrochlorothiazideZiac
How Bisoprolol, Hydrochlorothiazide interacts with Culver's Root (Blackroot) — through 1 ingredient. Tap an ingredient for the detail:
Culver's Root Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Culver's Root Root Extract + Bisoprolol, Hydrochlorothiazide interactionBumetanideBurinex
How Bumetanide interacts with Culver's Root (Blackroot) — through 1 ingredient. Tap an ingredient for the detail:
Culver's Root Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Culver's Root Root Extract + Bumetanide interactionBumetanide, PotassiumBurinex K
How Bumetanide, Potassium interacts with Culver's Root (Blackroot) — through 1 ingredient. Tap an ingredient for the detail:
Culver's Root Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Culver's Root Root Extract + Bumetanide, Potassium interactionCaffeine, Potassium Salicylate, SalicylamideTrim-Elim
How Caffeine, Potassium Salicylate, Salicylamide interacts with Culver's Root (Blackroot) — through 1 ingredient. Tap an ingredient for the detail:
Culver's Root Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Culver's Root Root Extract + Caffeine, Potassium Salicylate, Salicylamide interactionCandesartan Cilexetil, HydrochlorothiazideAtacand HCT
How Candesartan Cilexetil, Hydrochlorothiazide interacts with Culver's Root (Blackroot) — through 1 ingredient. Tap an ingredient for the detail:
Culver's Root Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Culver's Root Root Extract + Candesartan Cilexetil, Hydrochlorothiazide interactionCaptopril, HydrochlorothiazideAcezide, Capozide
How Captopril, Hydrochlorothiazide interacts with Culver's Root (Blackroot) — through 1 ingredient. Tap an ingredient for the detail:
Culver's Root Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Culver's Root Root Extract + Captopril, Hydrochlorothiazide interactionChlorothiazideDiuril
How Chlorothiazide interacts with Culver's Root (Blackroot) — through 1 ingredient. Tap an ingredient for the detail:
Culver's Root Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Culver's Root Root Extract + Chlorothiazide interactionChlorothiazide, MethyldopaAldochlor, Aldoclor 150, Aldoclor 250
How Chlorothiazide, Methyldopa interacts with Culver's Root (Blackroot) — through 1 ingredient. Tap an ingredient for the detail:
Culver's Root Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Culver's Root Root Extract + Chlorothiazide, Methyldopa interactionChlorothiazide, ReserpineDiupres
How Chlorothiazide, Reserpine interacts with Culver's Root (Blackroot) — through 1 ingredient. Tap an ingredient for the detail:
Culver's Root Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Culver's Root Root Extract + Chlorothiazide, Reserpine interactionChlorthalidoneHygroton, Thalitone
How Chlorthalidone interacts with Culver's Root (Blackroot) — through 1 ingredient. Tap an ingredient for the detail:
Culver's Root Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Culver's Root Root Extract + Chlorthalidone interactionChlorthalidone, ClonidineClorpres, Combipres
How Chlorthalidone, Clonidine interacts with Culver's Root (Blackroot) — through 1 ingredient. Tap an ingredient for the detail:
Culver's Root Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Culver's Root Root Extract + Chlorthalidone, Clonidine interactionCryptenamine, MethyclothiazideDiutensen
How Cryptenamine, Methyclothiazide interacts with Culver's Root (Blackroot) — through 1 ingredient. Tap an ingredient for the detail:
Culver's Root Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Culver's Root Root Extract + Cryptenamine, Methyclothiazide interactionCyclothiazideAnhydron, Fluidil
How Cyclothiazide interacts with Culver's Root (Blackroot) — through 1 ingredient. Tap an ingredient for the detail:
Culver's Root Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Culver's Root Root Extract + Cyclothiazide interactionDeserpidine, HydrochlorothiazideOreticyl, Oreticyl Forte
How Deserpidine, Hydrochlorothiazide interacts with Culver's Root (Blackroot) — through 1 ingredient. Tap an ingredient for the detail:
Culver's Root Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Culver's Root Root Extract + Deserpidine, Hydrochlorothiazide interactionDeserpidine, MethyclothiazideEnduronyl, Enduronyl Forte
How Deserpidine, Methyclothiazide interacts with Culver's Root (Blackroot) — through 1 ingredient. Tap an ingredient for the detail:
Culver's Root Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Culver's Root Root Extract + Deserpidine, Methyclothiazide interactionDigoxinDigitek, Lanoxicaps, Lanoxin
How Digoxin interacts with Culver's Root (Blackroot) — through 1 ingredient. Tap an ingredient for the detail:
Culver's Root Root ExtractDigoxin (lanoxin) Moderate
Interaction Summary
Theoretically, the overuse or abuse of black root can increase the risk of adverse effects of cardiac glycoside drugs.
Read the full Culver's Root Root Extract + Digoxin interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Culver's Root (Blackroot) with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Culver's Root Root Extract
Digoxin (Lanoxin)
Theoretically, the overuse or abuse of black root can increase the risk of adverse effects of cardiac glycoside drugs. Black root chemically binds with the glycosides while in the gastrointestinal (GI) tract, which may reduce their effectiveness if used concomitantly.
Diuretic Drugs
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia. Initiation of potassium supplementation or an increase in potassium supplement dose may be necessary for some patients. Some diuretics that can deplete potassium include chlorothiazide (Diuril), chlorthalidone (Thalitone), furosemide (Lasix), hydrochlorothiazide (HCTZ, Hydrodiuril, Microzide), and others.
Warfarin (Coumadin)
Black root has stimulant laxative effects. In some people black root can cause diarrhea. Diarrhea can increase the effects of warfarin, increase international normalized ratio (INR), and increase the risk of bleeding. Advise patients who take warfarin not to take excessive amounts of black root.
Brand information
Manufacturer and brand details for Culver's Root (Blackroot), from the product label.
Pure Herbs
See all Pure Herbs products- Name
- Pure Herbs, Ltd.
- City
- Sterling Heights
- State
- MI
- Phone Number
- (800) 860-4372
- Web Address
- www.pureherbs.com
Culver's Root (Blackroot) by Pure Herbs: Common Questions
Does Culver's Root (Blackroot) by Pure Herbs interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What does black root do?
Can I take this if I'm pregnant?
Is it safe to breastfeed while taking Culver's Root?
What side effects can black root cause?
Why is this risky with warfarin?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Culver's Root (Blackroot) is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Culver's Root (Blackroot)’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Culver's Root (Blackroot)'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 2 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Black Root 2 references
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Fetrow CW, Avila JR. Professional's Handbook of Complementary & Alternative Medicines. 1st ed. Springhouse, PA: Springhouse Corp., 1999.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC