Culver's Root Non-Alcohol Ingredients & Drug Interactions
by Hawaii Pharm
What is this page for?
First and foremost: checking Culver's Root Non-Alcohol against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Culver's Root Non-Alcohol is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for constipation, liver and gallbladder complaints, digestive upset.Based on those ingredients, 78 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are certified organic Culver's Root extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Culver's Root Non-Alcohol by Hawaii Pharm
Ask about any prescription or over-the-counter medication and we check it for interactions with Culver's Root Non-Alcohol by Hawaii Pharm — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of Culver's Root Non-Alcohol by Hawaii Pharm
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This product contains one active ingredient: certified organic Culver's Root extract (also known as black root). Black root is a plant extract traditionally used for its laxative properties.
The liquid also includes vegetable palm glycerin and Hawaiian artesian water as inactive ingredients.
Does it work?
Couldn't assess
The product facts we hold contain no effectiveness ratings for black root. We cannot tell you from our data whether it works for any intended use.
How safe is it?
Well-documented data
Black root can cause abdominal pain or cramps, nausea, vomiting, headache, drowsiness, and changes in stool color or odor. Large amounts have been linked to liver damage (hepatotoxicity).
Modern safety data are limited, and the fresh root can cause significant digestive toxicity. The safety data advise against using this product during pregnancy because of its strong laxative effect and lack of safety information.
Avoid it while breastfeeding as well — there isn't enough data to know it's safe.
Meds to double-check
Moderate interaction found
Double-check this product if you take blood thinners like warfarin (Moderate risk of increased bleeding), diuretics or water pills (Moderate risk of potassium loss), or digoxin for your heart (Moderate risk of reduced effectiveness). No interactions are documented for the ingredients we could check beyond these three drug types, but the medication count is substantial — use the search tool on this page to verify your specific drugs.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This is a single-ingredient laxative that carries real risks if you take blood thinners, diuretics, or heart medications. If you're on any prescription drug, check it here first.
Talk to your pharmacist before starting, especially if you have a history of liver problems or digestive issues.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 23, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Culver's Root Non-Alcohol, straight from the product label.
| Brand | Hawaii Pharm |
|---|---|
| Barcode (UPC) | 6339127909533 |
| Net contents | 4 Fluid Ounce(s); 120 mL |
| Market status | Off market |
| Date entered into DSLD | Oct 23, 2020 |
| DSLD ID | 238428 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating), Organic, Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Culver's Root Non-Alcohol by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| certified organic Culver's Root extract | 0 NP | -- |
Other ingredients: Vegetable Palm Glycerin, crystal clear artesian Hawaiian Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Hawaii Pharm Non-Alcohol Herbal Extract Highest quality since 2008
Made with Aloha!
Formulation
Contains no gluten, artificial colors, pesticides, preservatives, heavy metals. Non GMO.
Super concentrated liquid herbal extract Dry herb/menstruum ratio: 1:3
Contains no alcohol
Description: We produced this extract according to precise standards where each herbs are individually extracted according to their distinct characteristic. We use a cold maceration extraction method, so that the active constituents of the herbs are extracted and maintained.
Manufactured in an FDA registered facility. Ultra Sonic
Non GMO Gluten free
Made in USA, Hawaii
Suggested/Recommended/Usage/Directions
Directions for use: Shake well before using. Take about 20-30 drops in juice, water, tea or as desired up to four times per day.
Precautions
Warnings: Keep out of the reach of children.
Not to be used during pregnancy. Consult a physician before using if nursing or taking any medications.
Do not use if you are allergic to any ingredients.
Do not use if seal is broken or missing.
Storage
Refrigerate after opening.
Formula
(Veronicastrum virginicum)
FDA Statement of Identity
Herbal Dietary Supplement
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Seals/Symbols
FDA Registered Facility Made in United States of America USA
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Culver's Root Non-Alcohol by Hawaii Pharm label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Culver's Root Non-Alcohol by Hawaii Pharm
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size20 Drop(s) Dosage formLiquid Amounts shown are per serving.
Certified organic Culver's Root extract
Interacts with78 drugs
Black Root is a traditional North American herb that was historically used as a strong laxative and to support digestion and liver function. There is...
Certified organic Culver's Root extract monograph & interactionsOther (inactive) ingredients: Vegetable Palm Glycerin, Crystal clear artesian Hawaiian Water. These complete the product’s ingredient list but are not active constituents.
Culver's Root Non-Alcohol by Hawaii Pharm Drug Interactions
HelloPharmacist Interaction Report
Culver's Root Non-Alcohol by Hawaii Pharm contains black root extract, which interacts with a number of medications.
The most serious concern is with blood thinners like warfarin (Coumadin). Black root has strong laxative effects that can cause diarrhea, and diarrhea increases how much warfarin your body absorbs, raising your bleeding risk.
Don't take large amounts of this product if you're on warfarin.
Read the full breakdown — every affected drug type, severity by severity
Black root also affects diuretic drugs (water pills). It can worsen the potassium loss these drugs cause, leading to dangerously low potassium (hypokalemia).
Your doctor may need to increase your potassium supplement or monitor your levels more closely. Additionally, black root can chemically bind to digoxin (Lanoxin), a heart medication, and may reduce how well it works — overuse is a particular concern here.
Altogether, these interactions span 78 individual medications. Because of its strong laxative action and the number of drugs it affects, check your exact medications with the tool on this page before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Culver's Root Non-Alcohol?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Culver's Root Non-Alcohol interact with 78 drugs. Click any drug to see the details.
1 of the 1 ingredient in Culver's Root Non-Alcohol interact with drugs. Each result below shows which ingredient is responsible. certified organic Culver's Root extract
Acetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Culver's Root Non-Alcohol — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with Culver's Root Non-Alcohol — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root Extract + Acetaminophen, Pamabrom, Pyrilamine interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Culver's Root Non-Alcohol — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root Extract + Acetazolamide interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Culver's Root Non-Alcohol — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root Extract + Amiloride, Hydrochlorothiazide interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Culver's Root Non-Alcohol — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root Extract + Ammonium Chloride interactionAtenolol, ChlortalidoneAtenixCo, Tenoret 50, Totaretic
How Atenolol, Chlortalidone interacts with Culver's Root Non-Alcohol — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root Extract + Atenolol, Chlortalidone interactionAtenolol, ChlorthalidoneTenoretic
How Atenolol, Chlorthalidone interacts with Culver's Root Non-Alcohol — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root Extract + Atenolol, Chlorthalidone interactionAzilsartan, ChlorthalidoneEdarbyclor
How Azilsartan, Chlorthalidone interacts with Culver's Root Non-Alcohol — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root Extract + Azilsartan, Chlorthalidone interactionBenazepril, HydrochlorothiazideLotensin HCT
How Benazepril, Hydrochlorothiazide interacts with Culver's Root Non-Alcohol — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root Extract + Benazepril, Hydrochlorothiazide interactionBendroflumethiazideAprinox, Naturetin, Neo-NaClex
How Bendroflumethiazide interacts with Culver's Root Non-Alcohol — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root Extract + Bendroflumethiazide interactionBendroflumethiazide, NadololCorzide
How Bendroflumethiazide, Nadolol interacts with Culver's Root Non-Alcohol — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root Extract + Bendroflumethiazide, Nadolol interactionBendroflumethiazide, PotassiumCentyl K, Neo-NaClex-K
How Bendroflumethiazide, Potassium interacts with Culver's Root Non-Alcohol — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root Extract + Bendroflumethiazide, Potassium interactionBendroflumethiazide, Rauwolfia SerpentinaRauzide
How Bendroflumethiazide, Rauwolfia Serpentina interacts with Culver's Root Non-Alcohol — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root Extract + Bendroflumethiazide, Rauwolfia Serpentina interactionBenzthiazideExna
How Benzthiazide interacts with Culver's Root Non-Alcohol — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root Extract + Benzthiazide interactionBisoprolol, HydrochlorothiazideZiac
How Bisoprolol, Hydrochlorothiazide interacts with Culver's Root Non-Alcohol — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root Extract + Bisoprolol, Hydrochlorothiazide interactionBumetanideBurinex
How Bumetanide interacts with Culver's Root Non-Alcohol — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root Extract + Bumetanide interactionBumetanide, PotassiumBurinex K
How Bumetanide, Potassium interacts with Culver's Root Non-Alcohol — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root Extract + Bumetanide, Potassium interactionCaffeine, Potassium Salicylate, SalicylamideTrim-Elim
How Caffeine, Potassium Salicylate, Salicylamide interacts with Culver's Root Non-Alcohol — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root Extract + Caffeine, Potassium Salicylate, Salicylamide interactionCandesartan Cilexetil, HydrochlorothiazideAtacand HCT
How Candesartan Cilexetil, Hydrochlorothiazide interacts with Culver's Root Non-Alcohol — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root Extract + Candesartan Cilexetil, Hydrochlorothiazide interactionCaptopril, HydrochlorothiazideAcezide, Capozide
How Captopril, Hydrochlorothiazide interacts with Culver's Root Non-Alcohol — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root Extract + Captopril, Hydrochlorothiazide interactionChlorothiazideDiuril
How Chlorothiazide interacts with Culver's Root Non-Alcohol — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root Extract + Chlorothiazide interactionChlorothiazide, MethyldopaAldochlor, Aldoclor 150, Aldoclor 250
How Chlorothiazide, Methyldopa interacts with Culver's Root Non-Alcohol — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root Extract + Chlorothiazide, Methyldopa interactionChlorothiazide, ReserpineDiupres
How Chlorothiazide, Reserpine interacts with Culver's Root Non-Alcohol — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root Extract + Chlorothiazide, Reserpine interactionChlorthalidoneHygroton, Thalitone
How Chlorthalidone interacts with Culver's Root Non-Alcohol — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root Extract + Chlorthalidone interactionChlorthalidone, ClonidineClorpres, Combipres
How Chlorthalidone, Clonidine interacts with Culver's Root Non-Alcohol — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root Extract + Chlorthalidone, Clonidine interactionCryptenamine, MethyclothiazideDiutensen
How Cryptenamine, Methyclothiazide interacts with Culver's Root Non-Alcohol — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root Extract + Cryptenamine, Methyclothiazide interactionCyclothiazideAnhydron, Fluidil
How Cyclothiazide interacts with Culver's Root Non-Alcohol — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root Extract + Cyclothiazide interactionDeserpidine, HydrochlorothiazideOreticyl, Oreticyl Forte
How Deserpidine, Hydrochlorothiazide interacts with Culver's Root Non-Alcohol — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root Extract + Deserpidine, Hydrochlorothiazide interactionDeserpidine, MethyclothiazideEnduronyl, Enduronyl Forte
How Deserpidine, Methyclothiazide interacts with Culver's Root Non-Alcohol — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root Extract + Deserpidine, Methyclothiazide interactionDigoxinDigitek, Lanoxicaps, Lanoxin
How Digoxin interacts with Culver's Root Non-Alcohol — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root ExtractDigoxin (lanoxin) Moderate
Interaction Summary
Theoretically, the overuse or abuse of black root can increase the risk of adverse effects of cardiac glycoside drugs.
Read the full Certified Organic Culver's Root Extract + Digoxin interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Culver's Root Non-Alcohol with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
certified organic Culver's Root extract
Digoxin (Lanoxin)
Theoretically, the overuse or abuse of black root can increase the risk of adverse effects of cardiac glycoside drugs. Black root chemically binds with the glycosides while in the gastrointestinal (GI) tract, which may reduce their effectiveness if used concomitantly.
Diuretic Drugs
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia. Initiation of potassium supplementation or an increase in potassium supplement dose may be necessary for some patients. Some diuretics that can deplete potassium include chlorothiazide (Diuril), chlorthalidone (Thalitone), furosemide (Lasix), hydrochlorothiazide (HCTZ, Hydrodiuril, Microzide), and others.
Warfarin (Coumadin)
Black root has stimulant laxative effects. In some people black root can cause diarrhea. Diarrhea can increase the effects of warfarin, increase international normalized ratio (INR), and increase the risk of bleeding. Advise patients who take warfarin not to take excessive amounts of black root.
Brand information
Manufacturer and brand details for Culver's Root Non-Alcohol, from the product label.
Hawaii Pharm
See all Hawaii Pharm products- Name
- Hawaii Pharm LLC
- City
- Honolulu
- State
- HI
- ZipCode
- 96815
Culver's Root Non-Alcohol by Hawaii Pharm: Common Questions
Does Culver's Root Non-Alcohol by Hawaii Pharm interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant?
What side effects should I watch for?
Is this safe to breastfeed on?
What is black root used for?
Can I take more if it doesn't work?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Culver's Root Non-Alcohol is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Culver's Root Non-Alcohol’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Culver's Root Non-Alcohol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 2 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Black Root 2 references
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Fetrow CW, Avila JR. Professional's Handbook of Complementary & Alternative Medicines. 1st ed. Springhouse, PA: Springhouse Corp., 1999.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC