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Dietary supplement

D-Chiro-Inositol 50 mg Ingredients & Drug Interactions

by Zazzee Naturals

D-Chiro-Inositol 50 mg label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking D-Chiro-Inositol 50 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

D-Chiro-Inositol 50 mg is a dietary supplement by Zazzee Naturals with 1 active ingredient. Its ingredients are commonly taken for polycystic ovary syndrome (pcos), anxiety and panic, depression and mood.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are D-Chiro Inositol. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against D-Chiro-Inositol 50 mg by Zazzee Naturals

Ask about any prescription or over-the-counter medication and we check it for interactions with D-Chiro-Inositol 50 mg by Zazzee Naturals — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of D-Chiro-Inositol 50 mg by Zazzee Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: D-Chiro Inositol, 50 mg per capsule. It's a naturally occurring compound related to B vitamins that plays a role in how your body handles blood sugar and hormonal balance.

The capsule also contains inactive ingredients—cellulose and magnesium stearate—which are fillers and binders that hold the supplement together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: supports reproductive health and hormone levels.
  • We looked for evidence on: Polycystic ovary syndrome (PCOS), Infertility, Metabolic syndrome, ovulatory dysfunction, fertility support.
  • The strongest evidence on file: Inositol is rated "Possibly Effective" for Polycystic ovary syndrome (PCOS) (Natural Medicines).
  • Also on file: Inositol is rated "Possibly Effective" for Metabolic syndrome.
  • Also on file: Inositol is rated "Insufficient Reliable Evidence To Rate" for Infertility.

The evidence supports D-Chiro Inositol for a couple of uses. It's possibly effective for polycystic ovary syndrome (PCOS) and metabolic syndrome.

It's also possibly effective for preventing preterm labor, though that's a use that absolutely requires medical supervision. For anxiety, diabetic nerve pain, and depression, the evidence suggests it's possibly ineffective, so it's not the right choice if those are your main concerns.

The evidence, ingredient by ingredient Inositol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

D-Chiro Inositol is generally well tolerated at typical doses. The most common side effects when taken by mouth are diarrhea, gas, and nausea—usually mild and digestive in nature.

When combined with omega-3 fatty acids in clinical studies, there have been reports of cold and allergy symptoms in children, so that's worth noting if you're considering it for a child. There isn't enough reliable safety data for use in pregnancy, so if you're pregnant or planning to become pregnant, talk with your doctor before starting—don't use it on your own, even though some research has explored it in that context.

Side effects, ingredient by ingredient Inositol

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Inositol.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, double-check any antidiabetes medications you take—insulin, metformin, and similar drugs. D-Chiro Inositol can increase the risk of low blood sugar, so your doctor may need to adjust your dose or monitor you more carefully.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

D-Chiro Inositol may help if you have PCOS, metabolic syndrome, or are at risk for preterm labor and have medical oversight. If you take any diabetes medication, you need to check with your pharmacist first—this supplement can lower blood sugar.

It's gentle on most people, with mainly mild digestive side effects. Pregnancy use requires a doctor's guidance.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about D-Chiro-Inositol 50 mg, straight from the product label.

Brand Zazzee Naturals
Barcode (UPC) X001B7ZYKX
Net contents 90 Veggie Cap(s)
Market status On market
Date entered into DSLD Oct 24, 2022
DSLD ID 276080
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for D-Chiro-Inositol 50 mg by Zazzee Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veggie Capsule(s)
Maximum serving Sizes:
1 Veggie Capsule(s)
Servings per container
90
UPC/BARCODE
X001B7ZYKX
IngredientAmount% DV
D-Chiro Inositol50 mg--

Other ingredients: Cellulose, Cellulose, Powder, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested usage: As a dietary supplement, take 1 capsule per day with 2000 mg of myo-inositol.

Formulation

Research indicates that D-chiro-inositol supports overall reproductive health. Many studies have shown that D-chiro-inositol helps support healthy hormone levels and regular cycles. The research shows that the ideal ratio is 50 mg of D-chiro-inositol and 2000 mg of myo-inositol.

Not manufactured with wheat, gluten, soy, milk, egg, fish or shellfish.

Supports reproductive health Supports healthy myo-inositol levels Promotes a healthy cycle

Natural color variation may occur in this product.

Made with non GMO ingredients

Precautions

Allergen information: Contains carob derivates.

Not manufactured with wheat, gluten, soy, milk, egg, fish or shellfish. Produced in a GMP facility that processes other ingredients containing these allergens.

Warnings: For adults only.

Consult physician if pregnant or nursing, taking medication, or have a medical condition.

Keep out of reach of children.

Do not eat freshness packet. Keep in bottle.

Formula

D-chiro-inositol (Caronositol) 50 mg per capsule

FDA Statement of Identity

Dietary Supplement

Storage

Store in a cool, dry place after opening.

General Statements

Please recycle.

Brand IP Statement(s)

Caronositol is a Registered Trademark of BIOSEARCH, S.A.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

GMP Good Manufacturing Practice Consistent Quality

Made in USA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

D-Chiro-Inositol 50 mg by Zazzee Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

D-Chiro-Inositol 50 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in D-Chiro-Inositol 50 mg by Zazzee Naturals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Veggie Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

D-Chiro Inositol

Interacts with
86 drugs
50 mg per serving

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, m...

D-Chiro Inositol monograph & interactions

Other (inactive) ingredients: Cellulose, Cellulose, Powder, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

D-Chiro-Inositol 50 mg by Zazzee Naturals Drug Interactions

Want to check YOUR meds against D-Chiro-Inositol 50 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

D-Chiro Inositol 86

Individual Drug Interactions

The ingredients in D-Chiro-Inositol 50 mg interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in D-Chiro-Inositol 50 mg interact with drugs. Each result below shows which ingredient is responsible. D-Chiro Inositol

Each ingredient & the kinds of drugs it affects

For each ingredient in D-Chiro-Inositol 50 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

D-Chiro Inositol1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that inositol lowers blood glucose levels and glycated hemoglobin (HbA1c) levels in patients with diabetes.

Likelihood Possible Evidence A
D-Chiro Inositol full monograph & interactions
The maker

Brand information

Manufacturer and brand details for D-Chiro-Inositol 50 mg, from the product label.

Zazzee Naturals

See all Zazzee Naturals products
Name
Zazzee Naturals
Street Address
400 Rella Boulevard Suite 123 Dept. 182
City
Montebello
State
NY
ZipCode
10901
Pharmacist Counseling Corner

D-Chiro-Inositol 50 mg by Zazzee Naturals: Common Questions

Does D-Chiro-Inositol 50 mg by Zazzee Naturals interact with any medications?
Yes. Based on its ingredients, D-Chiro-Inositol 50 mg has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
D-Chiro-Inositol 50 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is D-Chiro Inositol and what does it do?
D-Chiro Inositol is a compound related to B vitamins that helps your body manage blood sugar and hormones. It's the active ingredient in this supplement, dosed at 50 mg per capsule.
Is it true that inositol can cause diarrhea or stomach upset?
Yes, the most common side effects when taken by mouth are diarrhea, gas, and nausea. These are usually mild, but if you're sensitive to digestive changes, start with a smaller dose or take it with food.
Can I take this if I'm pregnant?
There isn't enough reliable safety data to say it's okay on your own. If you're pregnant or planning to be, talk with your doctor first—some research has looked at it in pregnancy, but medical supervision is necessary.
Does this supplement actually work for PCOS or metabolic syndrome?
The evidence says D-Chiro Inositol is possibly effective for both PCOS and metabolic syndrome, meaning there's promising research behind it but it's not a guaranteed cure. Results vary from person to person.
What about the inactive ingredients—are there any fillers?
The capsule contains cellulose and magnesium stearate, which are standard inactive ingredients that help hold the supplement together. They're not active compounds, but they're necessary for the product to work.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if D-Chiro-Inositol 50 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

D-Chiro-Inositol 50 mg label
Go deeper

The Full Monographs Behind D-Chiro-Inositol 50 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Inositol

Interacts with 86 drugs

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, mood, and metabolic concerns. The stronge...

Read the full Inositol monograph →
Sources

Sources & How We Checked

D-Chiro-Inositol 50 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Inositol 14 references
  1. Palatnik A, Frolov K, Fux M, Benjamin J. Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. J Clin Psychopharmacol 2001;21:335-9.. PubMed
  2. Allan SJ, Kavanagh GM, Herd RM, Savin JA. The effect of inositol supplements on the psoriasis of patients taking lithium: a randomized, placebo-controlled trial. Br J Dermatol 2004;150:966-9. PubMed
  3. Machado-Vieira R, Viale CI, Kapczinski F. Mania associated with an energy drink: the possible role of caffeine, taurine, and inositol. Can J Psychiatry 2001;46:454-5. PubMed
  4. Kamenov Z, Kolarov G, Gateva A, Carlomagno G, Genazzani AD. Ovulation induction with myo-inositol alone and in combination with clomiphene citrate in polycystic ovarian syndrome patients with insulin resistance. Gynecol Endocrinol 2015;31(2):131-5. PubMed
  5. Matarrelli B, Vitacolonna E, D'Angelo M, et al. Effect of dietary myo-inositol supplementation in pregnancy on the incidence of maternal gestational diabetes mellitus and fetal outcomes: a randomized controlled trial. J Matern Fetal Neonatal Med 2013;26(1 PubMed
  6. Mukai T, Kishi T, Matsuda Y, Iwata N. A meta-analysis of inositol for depression and anxiety disorders. Hum Psychopharmacol 2014;29(1):55-63. PubMed
  7. Farren M, Daly N, McKeating A, Kinsley B, Turner MJ, Daly S. The Prevention of Gestational Diabetes Mellitus With Antenatal Oral Inositol Supplementation: A Randomized Controlled Trial. Diabetes Care. 2017;40(6):759-63. PubMed
  8. Zheng X, Liu Z, Zhang Y, et al. Relationship Between Myo-Inositol Supplementary and Gestational Diabetes Mellitus: A Meta-Analysis. Medicine (Baltimore). 2015;94(42):e1604. PubMed
  9. Crawford TJ, Crowther CA, Alsweiler J, Brown J. Antenatal dietary supplementation with myo-inositol in women during pregnancy for preventing gestational diabetes. Cochrane Database Syst Rev. 2015;(12):CD011507. PubMed
  10. Maurizi AR, Menduni M, Del Toro R, et al. A pilot study of D-chiro-inositol plus folic acid in overweight patients with type 1 diabetes. Acta Diabetol. 2017;54(4):361-65. PubMed
  11. Leppink EW, Redden SA, Grant JE. A double-blind, placebo-controlled study of inositol in trichotillomania. Int Clin Psychopharmacol. 2017;32(2):107-14. PubMed
  12. Lam S, Mandrekar SJ, Gesthalter Y. A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia. Cancer Prev Res (Phila). 2016;9(12):906-14.
  13. Wozniak J, Faraone SV, Chan J, et al. A randomized clinical trial of high eicosapentaenoic acid omega-3 fatty acids and inositol as monotherapy and in combination in the treatment of pediatric bipolar spectrum disorders: a pilot study. J Clin Psychiatry. PubMed
  14. Vitale SG, Corrado F, Caruso S, et al. Myo-inositol supplementation to prevent gestational diabetes in overweight non-obese women: bioelectrical impedance analysis, metabolic aspects, obstetric and neonatal outcomes - a randomized and open-label, placebo-

See these in context on the Inositol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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