Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

PREGNOSITOL Ingredients & Drug Interactions

by Zazzee Naturals

PREGNOSITOL label
See full label image
Powder Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking PREGNOSITOL against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

PREGNOSITOL is a dietary supplement by Zazzee Naturals with 2 active ingredients. Its ingredients are commonly taken for polycystic ovary syndrome (pcos), anxiety and panic, depression and mood.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Myo-Inositol. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against PREGNOSITOL by Zazzee Naturals

Ask about any prescription or over-the-counter medication and we check it for interactions with PREGNOSITOL by Zazzee Naturals — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of PREGNOSITOL by Zazzee Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Pregnositol contains 2 active ingredients: myo-inositol and D-chiro inositol. Both are naturally occurring compounds related to the B vitamins.

They're commonly paired together in supplements aimed at women's health, particularly for polycystic ovary syndrome (PCOS) and metabolic health. This product has no inactive ingredients listed.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: support female fertility and reproductive health.
  • We looked for evidence on: Infertility, Polycystic ovary syndrome (PCOS), ovulation, egg quality, hormone balance.
  • The strongest evidence on file: Inositol is rated "Possibly Effective" for Polycystic ovary syndrome (PCOS) (Natural Medicines).
  • Also on file: Inositol is rated "Insufficient Reliable Evidence To Rate" for Infertility.

For PCOS and metabolic syndrome, both ingredients in this product are rated possibly effective—meaning there's some evidence they may help, but more research is needed. They're also possibly effective for preterm labor.

For anxiety, diabetic nerve pain, and depression, the evidence suggests they're probably ineffective. The research here is mixed, so results may vary from person to person.

The evidence, ingredient by ingredient Inositol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both ingredients are generally well tolerated at common doses. The most frequent side effects are mild digestive ones: diarrhea, gas, and nausea.

One study noted that inositol combined with omega-3 fatty acids was linked to cold and allergy symptoms in some children, though this was with both ingredients together. During pregnancy, inositol has been studied but safety isn't fully established.

The data advises using it only under medical supervision if you're pregnant. There isn't enough reliable information on breastfeeding either, so check with your doctor or pharmacist for personalized advice.

Side effects, ingredient by ingredient Inositol

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Inositol.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any diabetes medications—insulin, metformin, sulfonylureas, or others—check them against the interaction list on this page before you start Pregnositol. The inositol in this product can theoretically increase the risk of low blood sugar (Moderate severity).

No other medication interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Pregnositol may be worth considering if you have PCOS or metabolic syndrome and want a well-tolerated option. If you take diabetes medications, you'll want to talk with your pharmacist first—this product can lower blood sugar.

If you're pregnant, breastfeeding, or planning to become pregnant, discuss it with your doctor before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about PREGNOSITOL, straight from the product label.

Brand Zazzee Naturals
Barcode (UPC) X0021XXIL3
Net contents 13.8 Ounce(s); 392 Gram(s)
Market status On market
Date entered into DSLD Sep 25, 2024
DSLD ID 318704
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult Female (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for PREGNOSITOL by Zazzee Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2.14 Gram(s)
Maximum serving Sizes:
2.14 Gram(s)
Servings per container
183
UPC/BARCODE
X0021XXIL3
IngredientAmount% DV
Myo-Inositol2000 mg--
D-Chiro Inositol50 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Usage: Take 1 level scoop once per day. Shake bottle well before each use. A pre-measured scoop is included to ensure perfect serving size. Mix contents with water or other beverage and consume with or in between meals. Stir well until completely dissolved before drinking.

Formulation

PREGNOSITOL is a balanced, scientifically formulated blend that helps support female fertility and overall reproductive health.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, or tree nut ingredients.

Premium grade fertility support Supports female fertility & reproductive health Supports healthy ovarian function

Natural color variation may occur in this product.

Gluten free Non GMO Soy free Dairy free Made with non GMO ingredients

100% Vegan

Formula

For maximum effectiveness, PREGNOSITOL contains an optimal 40:1 blend of Myo-Inositol and D-Chiro Inositol. Myo-Inositol has been shown, in numerous studies, to be a natural way to support healthy hormone balance, ovarian function, and egg quality. D-Chiro Inositol has been shown to enhance the overall effectiveness of Myo-Inositol when taken in the ideal 40:1 ratio with Myo-Inositol.

Optimal 40:1 Inositol Blend Myo-Inositol & D-Chiro Inositol Powder

Precautions

Allergen Information: Contains carob derivatives. Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Caution: In case of exceeding the suggested usage, sensitive individuals may experience mild gastrointestinal distress or diarrhea. If this occurs reduce dose to 1/2 level scoop or discontinue use.

Warnings: For adults only. Keep out of reach of children.

Consult physician if pregnant or nursing, taking medication, or have a medical condition.

Do not eat freshness packet.

FDA Statement of Identity

Dietary Supplement

Storage

Do not eat freshness packet. Keep in bottle. Store in a cool, dry place. This product is sold by weight, not by volume.

General Statements

Please recycle.

183 servings per container

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Good Manufacturing Practice GMP Consistent Quality Made in USA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

PREGNOSITOL by Zazzee Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

PREGNOSITOL label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in PREGNOSITOL by Zazzee Naturals

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2.14 Gram(s) Dosage formPowder Servings per container183 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Myo-Inositol

Interacts with
86 drugs
2000 mg per serving

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, m...

Myo-Inositol monograph & interactions

D-Chiro Inositol

Interacts with
86 drugs
50 mg per serving

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, m...

D-Chiro Inositol monograph & interactions
Interaction report

PREGNOSITOL by Zazzee Naturals Drug Interactions

Want to check YOUR meds against PREGNOSITOL?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Myo-Inositol 86

Individual Drug Interactions

The ingredients in PREGNOSITOL interact with 86 drugs. Click any drug to see the details.

1 of the 2 ingredients in PREGNOSITOL interact with drugs. Each result below shows which ingredient is responsible. Myo-Inositol

Each ingredient & the kinds of drugs it affects

For each ingredient in PREGNOSITOL with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Myo-Inositol1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that inositol lowers blood glucose levels and glycated hemoglobin (HbA1c) levels in patients with diabetes.

Likelihood Possible Evidence A
Myo-Inositol full monograph & interactions
The maker

Brand information

Manufacturer and brand details for PREGNOSITOL, from the product label.

Zazzee Naturals

See all Zazzee Naturals products
Name
Zazzee Naturals
Street Address
400 Rella Blvd Ste 123 Box 182
City
Montebello
State
NY
Web Address
ZazzeeNaturals.com
Pharmacist Counseling Corner

PREGNOSITOL by Zazzee Naturals: Common Questions

Does PREGNOSITOL by Zazzee Naturals interact with any medications?
Yes. Based on its ingredients, PREGNOSITOL has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
PREGNOSITOL contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my PCOS?
Both ingredients in Pregnositol are rated possibly effective for PCOS, so there's some evidence they might help—but the research isn't conclusive yet. Results vary from person to person. Talk to your doctor about whether it makes sense for you alongside your other treatments.
What are the most common side effects?
The most common ones are mild digestive issues: diarrhea, gas, and nausea. These tend to be mild and go away as your body adjusts. If they're bothersome, let your pharmacist know.
Is it safe to take while pregnant?
Inositol has been studied in pregnancy, but safety isn't fully established yet. The data advises using it only under medical supervision if you're pregnant. Talk to your doctor or midwife before taking it.
Can I take this if I'm breastfeeding?
There isn't enough reliable information on breastfeeding safety. Check with your doctor or pharmacist before using it—they can give you personalized advice based on your situation.
Does this product have fillers or other inactive ingredients?
No inactive ingredients are listed for this product—it's just the two active forms of inositol.
What's the difference between myo-inositol and D-chiro inositol?
Both are forms of inositol that work similarly in your body and have the same effectiveness ratings and safety profile. Many supplements pair them together because they complement each other, particularly for PCOS and metabolic health.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if PREGNOSITOL is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

PREGNOSITOL label
Go deeper

The Full Monographs Behind PREGNOSITOL’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Inositol

Interacts with 86 drugs

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, mood, and metabolic concerns. The stronge...

Read the full Inositol monograph →
Sources

Sources & How We Checked

PREGNOSITOL's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Inositol 14 references
  1. Palatnik A, Frolov K, Fux M, Benjamin J. Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. J Clin Psychopharmacol 2001;21:335-9.. PubMed
  2. Allan SJ, Kavanagh GM, Herd RM, Savin JA. The effect of inositol supplements on the psoriasis of patients taking lithium: a randomized, placebo-controlled trial. Br J Dermatol 2004;150:966-9. PubMed
  3. Machado-Vieira R, Viale CI, Kapczinski F. Mania associated with an energy drink: the possible role of caffeine, taurine, and inositol. Can J Psychiatry 2001;46:454-5. PubMed
  4. Kamenov Z, Kolarov G, Gateva A, Carlomagno G, Genazzani AD. Ovulation induction with myo-inositol alone and in combination with clomiphene citrate in polycystic ovarian syndrome patients with insulin resistance. Gynecol Endocrinol 2015;31(2):131-5. PubMed
  5. Matarrelli B, Vitacolonna E, D'Angelo M, et al. Effect of dietary myo-inositol supplementation in pregnancy on the incidence of maternal gestational diabetes mellitus and fetal outcomes: a randomized controlled trial. J Matern Fetal Neonatal Med 2013;26(1 PubMed
  6. Mukai T, Kishi T, Matsuda Y, Iwata N. A meta-analysis of inositol for depression and anxiety disorders. Hum Psychopharmacol 2014;29(1):55-63. PubMed
  7. Farren M, Daly N, McKeating A, Kinsley B, Turner MJ, Daly S. The Prevention of Gestational Diabetes Mellitus With Antenatal Oral Inositol Supplementation: A Randomized Controlled Trial. Diabetes Care. 2017;40(6):759-63. PubMed
  8. Zheng X, Liu Z, Zhang Y, et al. Relationship Between Myo-Inositol Supplementary and Gestational Diabetes Mellitus: A Meta-Analysis. Medicine (Baltimore). 2015;94(42):e1604. PubMed
  9. Crawford TJ, Crowther CA, Alsweiler J, Brown J. Antenatal dietary supplementation with myo-inositol in women during pregnancy for preventing gestational diabetes. Cochrane Database Syst Rev. 2015;(12):CD011507. PubMed
  10. Maurizi AR, Menduni M, Del Toro R, et al. A pilot study of D-chiro-inositol plus folic acid in overweight patients with type 1 diabetes. Acta Diabetol. 2017;54(4):361-65. PubMed
  11. Leppink EW, Redden SA, Grant JE. A double-blind, placebo-controlled study of inositol in trichotillomania. Int Clin Psychopharmacol. 2017;32(2):107-14. PubMed
  12. Lam S, Mandrekar SJ, Gesthalter Y. A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia. Cancer Prev Res (Phila). 2016;9(12):906-14.
  13. Wozniak J, Faraone SV, Chan J, et al. A randomized clinical trial of high eicosapentaenoic acid omega-3 fatty acids and inositol as monotherapy and in combination in the treatment of pediatric bipolar spectrum disorders: a pilot study. J Clin Psychiatry. PubMed
  14. Vitale SG, Corrado F, Caruso S, et al. Myo-inositol supplementation to prevent gestational diabetes in overweight non-obese women: bioelectrical impedance analysis, metabolic aspects, obstetric and neonatal outcomes - a randomized and open-label, placebo-

See these in context on the Inositol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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