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Dietary supplement

D-Ribose 850 mg Ingredients & Drug Interactions

by Wonder Laboratories

D-Ribose 850 mg label
See full label image
Capsule Category: Fiber And Other Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking D-Ribose 850 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

D-Ribose 850 mg is a dietary supplement by Wonder Laboratories with 1 active ingredient. Its ingredients are commonly taken for energy and fatigue, athletic performance and recovery, fibromyalgia symptoms.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are D-Ribose. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against D-Ribose 850 mg by Wonder Laboratories

Ask about any prescription or over-the-counter medication and we check it for interactions with D-Ribose 850 mg by Wonder Laboratories — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of D-Ribose 850 mg by Wonder Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: D-Ribose at 850 mg per capsule. D-Ribose is a five-carbon sugar that your body naturally produces and uses to make and rebuild muscle energy stores.

The capsule itself and the other ingredients — vegetable capsule material, magnesium stearate (a flow agent), and silica (an anti-caking agent) — are inactive.

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: Energy and athletic performance support.
  • We looked for evidence on: Athletic performance, Chronic fatigue syndrome (CFS), Fibromyalgia, Muscle soreness, Exercise recovery, Endurance — and 1 related terms.
  • The closest evidence on file: Ribose is rated "Possibly Ineffective" for Athletic performance (Natural Medicines).
  • Also on file: Ribose is rated "Insufficient Reliable Evidence To Rate" for Chronic fatigue syndrome (CFS), Fibromyalgia, Muscle soreness.

The evidence for D-Ribose is mixed and mostly limited. It's rated possibly ineffective for athletic performance and McArdle disease (a rare muscle disorder).

For restless legs syndrome, muscle soreness, congestive heart failure, and recovery from heart bypass surgery, we don't have enough reliable evidence to say whether it works or not.

The evidence, ingredient by ingredient Ribose

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

D-Ribose is generally well tolerated in the short term (up to about a month in studies), but long-term safety hasn't been well studied. The main concern is that it lowers blood sugar — a particular risk if you take insulin or antidiabetes drugs.

Common side effects taken by mouth include diarrhea, stomach discomfort, headache, nausea, and low blood sugar. A smaller number of people have reported anxiety, lightheadedness, or increased appetite; lowering the dose resolved these symptoms in some cases.

There isn't enough safety information to use D-Ribose during pregnancy or while breastfeeding — talk with your doctor or pharmacist before using it if either applies to you.

Side effects, ingredient by ingredient Ribose

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Ribose.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your exact medications if you take insulin or any antidiabetes drug (like metformin, glipizide, or glyburide) — ribose can lower blood sugar and boost their effect, raising your risk of hypoglycemia.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

D-Ribose is best considered if you're interested in muscle recovery and you don't take insulin or antidiabetes medications. If you do take those drugs, check with your pharmacist first — the interaction risk is real and may need monitoring.

It's not well-studied long-term, so this isn't a supplement to take indefinitely without a reason.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about D-Ribose 850 mg, straight from the product label.

Brand Wonder Laboratories
Barcode (UPC) 099528944903
Net contents 90 Vegetable Capsule(s)
Market status On market
Date entered into DSLD Sep 25, 2024
DSLD ID 315278
Product type Fiber And Other Nutrients
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for D-Ribose 850 mg by Wonder Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Vegetable Capsule(s)
Maximum serving Sizes:
6 Vegetable Capsule(s)
Servings per container
15
UPC/BARCODE
099528944903
IngredientAmount% DV
Calories25 Calorie(s)--
Total Carbohydrates6 Gram(s)2%
D-Ribose5100 mg--
Sugars5 Gram(s)--

Other ingredients: Vegetable capsule, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 3-6 vegetable capsules daily, prior to exercise. During training, serious athletes may want to double the dosage.

Precautions

Tamper evident: Do not use this product if imprinted foil seal under cap is broken or missing.

Keep out of reach of children.

Caution: If you are pregnant or nursing, consult your physician before taking this product.

Formulation

Mfg. in an FDA Registered Facility using Good Manufacturing Practices (GMPs)

Conforms to USP <2091> for weight. Meets USP <2040> disintegration for maximum bioavailability.

Contains: No artificial color, flavor or sweetener, no preservatives, no starch, no milk, no lactose, no soy, no wheat, no yeast, no fish and is sodium free.

Nutritionally supports healthy cardiovascular function and ATP energy production

Gluten free

Made in USA

Storage

Keep tightly closed. Store at room temperature: 59 degrees - 86 degrees F (15 degrees to 30 degrees C)

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Reorder #9441

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Ko Kosher Service

Formula

Ko Kosher Service

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

D-Ribose 850 mg by Wonder Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

D-Ribose 850 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in D-Ribose 850 mg by Wonder Laboratories

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Vegetable Capsule(s) Dosage formCapsule Servings per container15 Amounts shown are per serving.

D-Ribose

Interacts with
86 drugs
5100 mg per serving

Ribose (D-ribose) is a simple sugar your body makes naturally and uses to build energy molecules like ATP. Some people take it for fatigue, fibromyalg...

D-Ribose monograph & interactions

Other (inactive) ingredients: Vegetable capsule, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

D-Ribose 850 mg by Wonder Laboratories Drug Interactions

Want to check YOUR meds against D-Ribose 850 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

D-Ribose 86

Individual Drug Interactions

The ingredients in D-Ribose 850 mg interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in D-Ribose 850 mg interact with drugs. Each result below shows which ingredient is responsible. D-Ribose

Each ingredient & the kinds of drugs it affects

For each ingredient in D-Ribose 850 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

D-Ribose2 drug types · 86 drugs

Antidiabetes Drugs

Theoretically, taking ribose in combination with antidiabetes drugs might increase the risk of hypoglycemia.
In clinical research, ribose decreases serum glucose levels in a dose-dependent manner.

Likelihood Probable Evidence B
Insulin

Theoretically, taking ribose with insulin could increase the hypoglycemic effect of insulin.
In clinical pharmacokinetic studies, oral administration of ribose modestly increased serum insulin levels.

Likelihood Possible Evidence B
D-Ribose full monograph & interactions
The maker

Brand information

Manufacturer and brand details for D-Ribose 850 mg, from the product label.

Wonder Laboratories

See all Wonder Laboratories products
Name
Wonder Laboratories
Street Address
115 S.C.T. Ct.
City
White House
State
TN
ZipCode
37188
Pharmacist Counseling Corner

D-Ribose 850 mg by Wonder Laboratories: Common Questions

Does D-Ribose 850 mg by Wonder Laboratories interact with any medications?
Yes. Based on its ingredients, D-Ribose 850 mg has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
D-Ribose 850 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take D-Ribose if I have type 2 diabetes or take insulin?
Not without talking to your doctor or pharmacist first. D-Ribose lowers blood sugar on its own, and combining it with insulin or antidiabetes drugs raises your risk of low blood sugar (hypoglycemia). Your doctor may decide it's okay and adjust your medication, or they may advise against it.
Does D-Ribose really help athletic performance?
The evidence doesn't support it. D-Ribose is rated possibly ineffective for athletic performance based on the research we've reviewed.
What are the most common side effects?
Diarrhea, stomach discomfort, headache, and nausea are most often reported. Some people also experience low blood sugar, anxiety, lightheadedness, or increased appetite, though these are less common. Lowering your dose has resolved side effects in some cases.
Is it safe to take D-Ribose long-term?
The evidence is limited. Studies have looked at safety for about a month, but long-term safety hasn't been well studied. Talk with your pharmacist about how long you're planning to use it.
Can I take D-Ribose while pregnant or breastfeeding?
There isn't enough safety information to recommend it during pregnancy or while breastfeeding. Talk with your doctor or pharmacist to decide what's right for you.
Does D-Ribose help with muscle soreness or recovery from heart surgery?
The evidence is insufficient to say. While some people use it for these purposes, we don't have enough reliable research to know whether it actually works.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if D-Ribose 850 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

D-Ribose 850 mg label
Go deeper

The Full Monographs Behind D-Ribose 850 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Ribose

Interacts with 86 drugs

Ribose (D-ribose) is a simple sugar your body makes naturally and uses to build energy molecules like ATP. Some people take it for fatigue, fibromyalgia, exercise recovery, or heart conditio...

Read the full Ribose monograph →
Sources

Sources & How We Checked

D-Ribose 850 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Ribose 8 references
  1. Segal S, Foley J. The metabolism of D-ribose in man. J Clin Invest 1958;37:719-35. PubMed
  2. Perlmutter NS, Wilson RA, Angello DA, et al. Ribose facilitates thallium-201 redistribution in patients with coronary artery disease. J Nucl Med 1991;32:193-200.
  3. Hegewald MG, Palac RT, Angello DA, et al. Ribose infusion accelerates thallium redistribution with early imaging compared with late 24-hour imaging without ribose. J Am Coll Cardiol 1991;18:1671-81. PubMed
  4. Pliml W, von Arnim T, Stalein A, et al. Effects of ribose on excercise-induced ischaemia in stable coronary artery disease. Lancet 1992;340:507-10.
  5. Burke ER. D-Ribose What You Need To Know. Garden City Park, NY: Avery Publishing Group 1999;1-43.
  6. Gross M, Reiter S, Zollner N. Metabolism of D-ribose administered continuously to healthy persons and to patients with myoadenylate deaminase deficiency. Klin Wochenschr 1989;67:1205-13. PubMed
  7. Teitelbaum JE, Johnson C, St Cyr J. The use of D-ribose in chronic fatigue syndrome and fibromyalgia: a pilot study. J Altern Complement Med 2006;12:857-62. PubMed
  8. Thompson J, Neutel J, Homer K, Tempero K, Shah A, Khankari R. Evaluation of D-ribose pharmacokinetics, dose proportionality, food effect, and pharmacodynamics after oral solution administration in healthy male and female subjects. J Clin Pharmacol 2014;54 PubMed

See these in context on the Ribose monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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