Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Daily Energy Tropical Passion Ingredients & Drug Interactions

by OLLY

Daily Energy Tropical Passion label
See full label image
Gummy Or Jelly Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Daily Energy Tropical Passion against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Daily Energy Tropical Passion is a dietary supplement by OLLY with 3 active ingredients. Its ingredients are commonly taken for treating or preventing b12 deficiency, pernicious anemia, low energy and fatigue.Based on those ingredients, 1,018 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Goji Berry Fruit Juice, Powder, Coenzyme Q-10, Vitamin B12. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Daily Energy Tropical Passion by OLLY

Ask about any prescription or over-the-counter medication and we check it for interactions with Daily Energy Tropical Passion by OLLY — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Daily Energy Tropical Passion by OLLY

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

OLLY Daily Energy Tropical Passion is a gummy supplement with three active ingredients. Vitamin B12 supports energy and nervous system function.

Goji berry fruit juice and powder are included for their traditional role in wellness—though evidence for most specific health claims is limited or insufficient. Coenzyme Q-10 is an antioxidant your body makes naturally and uses for cell energy.

The remaining ingredients are inactive—glucose syrup, beet sugar, gelatin, pectin, and juices (orange, carrot, blueberry) for taste and texture, plus lactic acid, citric acid, vegetable oil, carnauba wax, and natural flavor.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: steady flow of energy.
  • We looked for evidence on: Fatigue, Chemotherapy-related fatigue, Chronic fatigue syndrome (CFS), Low energy, Energy metabolism, Cellular energy production.
  • The closest evidence on file: Coenzyme Q10 is rated "Possibly Ineffective" for Chemotherapy-related fatigue (Natural Medicines).
  • Also on file: Vitamin B12 is rated "Insufficient Reliable Evidence To Rate" for Fatigue.
  • Also on file: Coenzyme Q10 is rated "Insufficient Reliable Evidence To Rate" for Chronic fatigue syndrome (CFS), Fatigue.

Vitamin B12 is effective for treating actual B12 deficiency and certain rare conditions, and possibly effective for canker sores and nerve pain from shingles (postherpetic neuralgia). Coenzyme Q-10 is likely effective for genetic CoQ-10 deficiency and possibly effective for fibromyalgia, migraine, heart failure, and diabetic nerve damage.

For goji berry, the evidence isn't established—we hold insufficient data to rate its effects on heart health, blood pressure, weight, or quality of life.

The evidence, ingredient by ingredient Vitamin B12 Goji Coenzyme Q10

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin B12 is generally very safe; your body flushes excess in urine and there's no established upper limit. It's considered safe in pregnancy and while breastfeeding at normal recommended amounts.

Coenzyme Q-10 is generally well tolerated, though gastrointestinal side effects like nausea, diarrhea, and heartburn occur in less than 1% of people; headache, dizziness, and insomnia have been reported rarely. CoQ-10 safety in pregnancy is not well studied, so caution is advised; the same goes for breastfeeding.

Goji berry, common as a food, is generally safe, but concentrated supplements have less safety data. Avoid medicinal amounts during pregnancy due to limited safety data and historical concerns about uterine effects.

Breastfeeding safety is unclear—use caution and check with your doctor. A small number of people have reported allergic reactions (rash, itching, facial swelling, even anaphylaxis), and very rarely, liver inflammation has been linked to goji or combination products containing it.

Side effects, ingredient by ingredient Vitamin B12 Goji Coenzyme Q10

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Vitamin B12, Coenzyme Q10, Goji.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 1,019 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take warfarin or other blood thinners—goji berry can increase bleeding risk, and coenzyme Q-10 may reduce warfarin's effect. Also flag blood pressure medications, diabetes drugs, heart rhythm medications (especially flecainide), antidepressants or other drugs your liver breaks down via CYP pathways, and any chemotherapy.

If you take metformin for diabetes, your doctor may want to monitor your B12 level.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.

This product may help with energy if you're B12-deficient or low in CoQ-10, but goji's own benefits aren't well proven in our data. If you take warfarin, blood pressure drugs, diabetes medications, antiarrhythmias, or certain chemotherapy drugs, you need to check this product with your doctor or pharmacist before starting—the interactions are real and can affect how your medications work.

Pregnant women should avoid the goji component specifically. Talk it over with your own healthcare provider to see if this fits your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Daily Energy Tropical Passion, straight from the product label.

Brand OLLY
Barcode (UPC) 840160200700
Net contents 120 Gummy(ies)
Market status On market
Date entered into DSLD Jun 22, 2023
DSLD ID 290587
Product type Other Combinations
Supplement form Gummy Or Jelly
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Daily Energy Tropical Passion by OLLY, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Gummy(ies)
Maximum serving Sizes:
2 Gummy(ies)
Servings per container
60
UPC/BARCODE
840160200700
IngredientAmount% DV
Calories15 Calorie(s)--
Total Carbohydrates3 Gram(s)1%
Vitamin B12300 mcg12500%
Added Sugars2 Gram(s)4%
Total Sugars2 Gram(s)--
Goji Berry Fruit Juice, Powder100 mg--
Coenzyme Q-1030 mg--

Other ingredients: Glucose Syrup, Beet Sugar, Water, Gelatin, Orange juice concentrate, Lactic Acid, Citric Acid, Natural flavor, Pectin, Vegetable Oil, Carnauba Wax, Carrot Juice, Blueberry Juice

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

100% Caffeine free

For a steady flow of energy

No synthetic flavors or colors Gluten free

Formula

Vitamin B12 + CoQ10 & Goji Berry

Tropical passion with other natural flavors

The goods inside B12 The bee's knees. This active vitamin is essential for the production of cellular energy - the fuel your body needs to burn without burnout. CoQ10 A key component that helps support your mitochondria, the energy producing structures that keep your cells powered up. Goji Berry A super food used for centuries to help maintain a steady flow of energy. Go Goji, Go.

Naturally tasty A tropical blend with passion fruit.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Tear here 1. Hold open middle flap with finger 2. Pull both sides apart to open

Take on the daily No food or water necessary. Suggested Use: Take 2 gummies daily. Chew thoroughly before swallowing.

Precautions

This package is child resistant.

Processed in a facility with products that may contain soy, egg, peanuts, tree nuts, milk, fish, shellfish and wheat.

Take only as directed. Do not exceed suggested use.

If you have a medical condition, are on medication, or are pregnant or nursing please seek the advice of a qualified health care professional before using.

Not intended for use in children. Keep out of the reach of children.

Do not use if pouch is torn or open.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Storage

Store in a cool, dry place.

General Statements

Multi-layer pouch how2recycle.info

Seals/Symbols

Certified B Corporation

Brand IP Statement(s)

Copyright 2021 OLLY PBC

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Daily Energy Tropical Passion by OLLY label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Daily Energy Tropical Passion label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Daily Energy Tropical Passion by OLLY

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Gummy(ies) Dosage formGummy Or Jelly Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin B12

Interacts with
20 drugs
300 mcg per serving Form: Cyanocobalamin

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very h...

Vitamin B12 monograph & interactions

Goji Berry Fruit Juice, Powder

Interacts with
1,000 drugs
100 mg per serving Form: Lycium barbarum Fruit Juice, Powder

Goji berries are a nutritious fruit rich in antioxidants, vitamins, and plant polysaccharides, and they are safe for most people as a food. While they...

Goji Berry Fruit Juice, Powder monograph & interactions

Coenzyme Q-10

Interacts with
198 drugs
30 mg per serving Form: Ubiquinone

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...

Coenzyme Q-10 monograph & interactions

Other (inactive) ingredients: Glucose Syrup, Beet Sugar, Water, Gelatin, Orange juice concentrate, Lactic Acid, Citric Acid, Natural flavor, Pectin, Vegetable Oil, Carnauba Wax, Carrot Juice, Blueberry Juice. These complete the product’s ingredient list but are not active constituents.

Interaction report

Daily Energy Tropical Passion by OLLY Drug Interactions

Want to check YOUR meds against Daily Energy Tropical Passion?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,018Drugs
2 Major 948 Moderate 68 Minor

Ingredients driving the most interactions

Goji Berry Fruit Juice, Powder 1,000
Coenzyme Q-10 198
Vitamin B12 20

Individual Drug Interactions

The ingredients in Daily Energy Tropical Passion interact with 1,018 drugs. Click any drug to see the details.

3 of the 3 ingredients in Daily Energy Tropical Passion interact with drugs. Each result below shows which ingredient is responsible. Goji Berry Fruit Juice, Powder Coenzyme Q-10 Vitamin B12

Each ingredient & the kinds of drugs it affects

For each ingredient in Daily Energy Tropical Passion with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Goji Berry Fruit Juice, Powder8 drug types · 1,000 drugs

Warfarin (Coumadin)

Goji can increase the effects of warfarin and possibly increase the risk of bleeding.
There are at least 5 case reports of increased international normalized ratio (INR) in patients stabilized on warfarin who began drinking goji juice, concentrated goji tea, or goji wine. Goji may inhibit the metabolism of warfarin by cytochrome P450 2C9 (CYP2C9).

Likelihood Probable Evidence D
Antihypertensive Drugs

Theoretically, concomitant use of goji root bark, but not goji fruit, with antihypertensive drugs might have additive effects.
Animal and in vitro research suggest that goji root bark has hypotensive effects. However, goji fruit juice does not appear to reduce systolic or diastolic blood pressure in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, goji berry might inhibit CYP2C19 and reduce metabolism of CYP2C19 substrates.
In vitro research shows that goji berry tincture and juice inhibit CYP2C19 enzymes. Concomitant use with goji may decrease metabolism and increase levels of CYP2C19 substrates. However, this has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, goji berry might inhibit CYP2C9 and reduce metabolism of CYP2C9 substrates.
In vitro research shows that goji berry tincture and juice inhibit CYP2C9 enzymes. Additionally, multiple case reports suggest that goji berry concentrated tea and juice inhibit the metabolism of warfarin, a CYP2C9 substrate. Concomitant use with goji may decrease metabolism and increase levels of CYP2C9 substrates.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, goji berry might inhibit CYP2D6 and reduce metabolism of CYP2D6 substrates.
In vitro research shows that goji berry juice inhibits CYP2D6 enzymes. Concomitant use with goji may decrease metabolism and increase levels of CYP2D6 substrates. However, this has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, goji berry might inhibit CYP3A4 and reduce metabolism of CYP3A4 substrates.
In vitro research shows that goji berry juice inhibits CYP3A4 enzymes. Concomitant use with goji may decrease metabolism and increase levels of CYP3A4 substrates. However, this has not been reported in humans.

Likelihood Possible Evidence D
Flecainide (Tambocor)

Theoretically, goji berry might increase the levels and clinical effects of flecainide.
In one case report, a 75-year-old patient stable on flecainide and warfarin presented to the emergency room with fainting and pleomorphic arrhythmia caused by flecainide toxicity. Flecainide toxicity was attributed to drinking 1-2 glasses of concentrated goji tea daily for 2 weeks. Theoretically, goji may have inhibited the cytochrome P450 2D6 (CYP2D6) metabolism of flecainide.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, concomitant use of goji fruit polysaccharides or goji root bark with antidiabetes drugs might have additive effects.
Animal and in vitro research show that goji root bark and fruit polysaccharides might have hypoglycemic effects. However, clinical research has only shown that taking goji fruit polysaccharides with or without antidiabetes drugs modestly reduces postprandial glucose when compared with control, with no reports of hypoglycemia.

Likelihood Possible Evidence B
Goji Berry Fruit Juice, Powder full monograph & interactions

Coenzyme Q-103 drug types · 198 drugs

Alkylating Agents

Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.

Likelihood Possible Evidence B
Coenzyme Q-10 full monograph & interactions

Vitamin B121 drug type · 20 drugs

Metformin (Glucophage)

Metformin, a common medication used to manage type 2 diabetes, has been associated with lower vitamin B12 levels in some individuals. Prolonged use of metformin can interfere with the absorption of B12 in the digestive system, potentially leading to a deficiency in this essential vitamin.

Likelihood Possible Evidence A
Vitamin B12 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Daily Energy Tropical Passion, from the product label.

OLLY

See all OLLY products
Name
OLLY Public Benefit Corp.
City
San Francisco
State
CA
ZipCode
94111
Phone Number
1-844-439-6559
Web Address
OLLY.com
Pharmacist Counseling Corner

Daily Energy Tropical Passion by OLLY: Common Questions

Does Daily Energy Tropical Passion by OLLY interact with any medications?
Yes. Based on its ingredients, Daily Energy Tropical Passion has a known interaction with 1,018 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Daily Energy Tropical Passion contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this give me energy?
Vitamin B12 helps your body make energy from food, so if you're deficient in it, B12 supplements can restore that. Goji and CoQ-10 are included for wellness, though goji's effectiveness for energy isn't proven in our data. If you're already getting enough B12, this supplement won't boost energy above normal.
Is it safe if I'm pregnant?
Vitamin B12 is safe in pregnancy at recommended amounts. Coenzyme Q-10 lacks enough safety data in pregnancy, so caution is advised—talk with your doctor. Goji berry should be avoided at medicinal amounts during pregnancy due to limited safety data and traditional concerns about effects on the uterus.
Can I take this while breastfeeding?
Vitamin B12 is safe while breastfeeding at recommended amounts. CoQ-10 and goji berry haven't been well studied in breastfeeding—use caution and check with your doctor before starting.
What are the side effects?
Vitamin B12 is very well tolerated. CoQ-10 may cause stomach upset, nausea, diarrhea, or heartburn in less than 1% of people, and headache or dizziness rarely. Goji berry can trigger allergic reactions like rash or itching in a small number of people, and very rarely has been linked to liver problems.
Does this product have fillers?
Yes—besides the three active ingredients, it contains glucose syrup, beet sugar, gelatin, juices, and various binders and flavorings to make it a gummy.
What is coenzyme Q-10 for?
CoQ-10 is a naturally occurring compound your body uses to generate energy in cells and as an antioxidant. It's likely effective for genetic CoQ-10 deficiency and possibly helpful for fibromyalgia, migraine, heart failure, and diabetic nerve damage.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Daily Energy Tropical Passion label
Go deeper

The Full Monographs Behind Daily Energy Tropical Passion’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin B12

Interacts with 20 drugs

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very helpful for people who are deficient — su...

Read the full Vitamin B12 monograph → Herb & supplement monograph

Goji

Interacts with 1,000 drugs

Goji berries are a nutritious fruit rich in antioxidants, vitamins, and plant polysaccharides, and they are safe for most people as a food. While they are popular for eye health, immune supp...

Read the full Goji monograph → Herb & supplement monograph

Coenzyme Q10

Interacts with 198 drugs

CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated and is most studied for heart condition...

Read the full Coenzyme Q10 monograph →
Sources

Sources & How We Checked

Daily Energy Tropical Passion's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 84 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin B12 30 references
  1. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  2. Hartman TJ, Woodson K, Stolzenberg-Solomon R, et al. Association of the B-vitamins pyridoxal 5'-phosphate (B6), B12, and folate with lung cancer risk in older men. Am J Epidemiol 2001;153:688-94.. DOI
  3. Jansen T, Romiti R, Kreuter A, Altmeyer P. Rosacea fulminans triggered by high-dose vitamins B6 and B12. J Eur Acad Dermatol Venereol 2001;15:484-5..
  4. Lange H, Suryapranata H, De Luca G, et al. Folate therapy and in-stent restenosis after coronary stenting. N Engl J Med 2004;350:2673-81. PubMed
  5. Collin, S. M., Metcalfe, C., Refsum, H., Lewis, S. J., Zuccolo, L., Smith, G. D., Chen, L., Harris, R., Davis, M., Marsden, G., Johnston, C., Lane, J. A., Ebbing, M., Bonaa, K. H., Nygard, O., Ueland, P. M., Grau, M. V., Baron, J. A., Donovan, J. L., Nea
  6. Geissbuhler, P., Mermillod, B., and Rapin, C. H. Elevated serum vitamin B12 levels associated with CRP as a predictive factor of mortality in palliative care cancer patients: a prospective study over five years. J.Pain Symptom.Manage. 2000;20(2):93-103. PubMed
  7. Salles, N., Herrmann, F., Sakbani, K., Rapin, C. H., and Sieber, C. High vitamin B12 level: a strong predictor of mortality in elderly inpatients. J Am Geriatr.Soc 2005;53(5):917-918.
  8. Looker, H. C., Fagot-Campagna, A., Gunter, E. W., Pfeiffer, C. M., Sievers, M. L., Bennett, P. H., Nelson, R. G., Hanson, R. L., and Knowler, W. C. Homocysteine and vitamin B(12) concentrations and mortality rates in type 2 diabetes. Diabetes Metab Res R
  9. Uhl, W., Nolting, A., Golor, G., Rost, K. L., and Kovar, A. Safety of hydroxocobalamin in healthy volunteers in a randomized, placebo-controlled study. Clin Toxicol (Phila) 2006;44 Suppl 1:17-28. PubMed
  10. Borron, S. W., Baud, F. J., Barriot, P., Imbert, M., and Bismuth, C. Prospective study of hydroxocobalamin for acute cyanide poisoning in smoke inhalation. Ann Emerg.Med 2007;49(6):794-801, 801. PubMed
  11. Borron, S. W., Baud, F. J., Megarbane, B., and Bismuth, C. Hydroxocobalamin for severe acute cyanide poisoning by ingestion or inhalation. Am J Emerg.Med 2007;25(5):551-558. PubMed
  12. Lewis, J. G. Gout, Steatorrhoea, and Megaloblastic Anaemia. Ann Rheum.Dis 1962;21(3):284-286. PubMed
  13. Tal, S., Shavit, Y., Stern, F., and Malnick, S. Association between vitamin B12 levels and mortality in hospitalized older adults. J Am Geriatr.Soc 2010;58(3):523-526. PubMed
  14. Baztan, J. J., Gavidia, J. J., Gomez-Pavon, J., Esteve, A., and Ruiperez, I. High vitamin B12 levels and in-hospital mortality. J Am Geriatr.Soc 2010;58(11):2237-2238. PubMed
  15. Omboni, E., Checchini, M., and Longoni, F. [Hypopotassemia and megaloblastic anemia. Presentation of a case]. Minerva Med 8-31-1987;78(16):1255-1257.
  16. Aalfs As, Scholvinck LH, Horvath B. Acneiform eruption in a 5-year old due to vitamin B12 supplementation. Eur J Dermatol 2013;23(5):726-7. PubMed
  17. Balta I, Ozuguz P. Vitamin B12-induced acneiform eruption. Cutan Ocul Toxicol 2014;33(2):94-5. PubMed
  18. Carman KB, Belgemen T, Yis U. Involuntary movements misdiagnosed as seizure during vitamin B12 treatment. Pediatr Emerg Care 2013;29(11):1223-4. PubMed
  19. Djuric V, Bogic M, Popadic AP, et al. Anaphylactic reaction to hydroxycobalamin with tolerance to cyanocobalamin. Ann Allergy Asthma Immunol 2012;108(3):207-8. PubMed
  20. Kartel O, Gulec M, Demirel F, et al. Vitamin B12 allergy and successful desensitization with cyanocobalamin: A case report. Allergol Immunopath (Madr) 2012;40(5):324-5.
  21. Patiroglu T, Unal E, Yildirim S. Infantile tremor syndrome associated with cobalamin therapy: A case report. Clin Neurol Neurosurg 2013;115(9):1903-5. PubMed
  22. Schulte S, Barkema LW, Kardaun SH. Long-lasting atypical acneiform eruption with prominent comedones induced by hydroxocobalamin (vitamin B12). J Dtsch Dermatol Ges 2014;12(6):502-3.
  23. Zanus C, Alberini E, Costa P, et al. Involuntary movements after correction of vitamin B12 deficiency: A video-case report. Epileptic Disord 2012;14(2):174-80. PubMed
  24. Fanidi A, Carreras-Torres R, Larose TL, et al. Is high vitamin B12 status a cause of lung cancer? Int J Cancer. 2019 Sep 15;145(6):1499-1503. PubMed
  25. Fujita Y, Mizukami T, Maya Y, et al. Vitamin B12 allergy manifesting as lymphomatoid contact dermatitis. Eur J Dermatol. 2020;30(3):304-305. PubMed
  26. Dépret F, Hoffmann C, Daoud L, et al. Association between hydroxocobalamin administration and acute kidney injury after smoke inhalation: a multicenter retrospective study. Crit Care. 2019;23(1):421. PubMed
  27. Khairan P, Sobue T, Eshak ES, et al. Association of dietary intakes of vitamin B12, vitamin B6, folate, and methionine with the risk of esophageal cancer: the Japan Public Health Center-based (JPHC) prospective study. BMC Cancer 2021;21(1):982. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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