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Dietary supplement

David Winston's AF Compound Ingredients & Drug Interactions

by Herbalist & Alchemist

David Winston's AF Compound label
See full label image
Liquid Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking David Winston's AF Compound against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

David Winston's AF Compound is a dietary supplement by Herbalist & Alchemist with 6 active ingredients. Its ingredients are commonly taken for intestinal parasites and worms, digestive complaints, antimicrobial and antifungal support.Based on those ingredients, 88 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Myrrh extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against David Winston's AF Compound by Herbalist & Alchemist

Ask about any prescription or over-the-counter medication and we check it for interactions with David Winston's AF Compound by Herbalist & Alchemist — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of David Winston's AF Compound by Herbalist & Alchemist

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 6 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (2 mL) without saying how much of each component you get.

This liquid contains six ingredients: Black Walnut extract, Yellow Root extract, Spilanthes extract, Myrrh extract, Usnea lichen extract, and Cardamom extract. The product is delivered in a base of ethyl alcohol, distilled water, and vegetable glycerin.

We don't have effectiveness data on file for most of these — the evidence on Black Walnut for heart disease and wound healing is insufficient to rate, and the same goes for Usnea lichen and Cardamom across several conditions. Myrrh shows insufficient evidence for a number of uses too, though it's rated likely ineffective for schistosomiasis.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Supports normal systemic flora.
  • We looked for evidence on: Intestinal parasite infection, Diarrhea, Dyspepsia, Irritable bowel syndrome (IBS), Crohn disease, Ulcerative colitis — and 4 related terms.
  • The closest evidence on file: Myrrh is rated "Insufficient Reliable Evidence To Rate" for Crohn disease (Natural Medicines).
  • Also on file: Myrrh is rated "Insufficient Reliable Evidence To Rate" for Diarrhea, Ulcerative colitis, Intestinal parasite infection, Irritable bowel syndrome (IBS).
  • Also on file: Cardamom is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia, Irritable bowel syndrome (IBS).

The evidence we hold on these ingredients doesn't establish that any of them work reliably for their purported uses. Black Walnut, Myrrh, Usnea lichen, and Cardamom all carry ratings of insufficient reliable evidence or likely ineffective for the conditions they're traditionally used for — which means the research either isn't there yet or isn't strong enough to call them effective.

We have no effectiveness data on file for Yellow Root or Spilanthes.

The evidence, ingredient by ingredient Black Walnut Myrrh Usnea Cardamom

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Black Walnut is generally well tolerated when it's the fruit nut, but the leaf, bark, and hull contain high amounts of tannins and can cause gastrointestinal upset. The facts note that long-term safety isn't well studied, and it should be avoided in pregnancy and while breastfeeding.

Myrrh is likely fine for short-term topical or mouth-rinse use, but oral safety isn't well established — and it should be avoided in pregnancy because it may stimulate the uterus. Usnea lichen carries a caution about oral use, as its constituent usnic acid has been linked to liver damage; avoid it in pregnancy and while breastfeeding.

Cardamom in food amounts is generally well tolerated, though concentrated supplement doses lack safety data.

Side effects, ingredient by ingredient Black Walnut Myrrh Usnea Cardamom

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 4 matched ingredients can interact with medications — Myrrh.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 88 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take diabetes medications, check with your pharmacist — myrrh may increase your risk of low blood sugar. If you're on warfarin or another blood thinner, myrrh may make it less effective and you'll need to verify it's safe.

We couldn't check Yellow Root or Spilanthes, so let your pharmacist know you're taking those too.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

If you take antidiabetes medications or blood thinners like warfarin, check with your pharmacist before starting this product. Black Walnut, myrrh, and usnea lichen all carry pregnancy and breastfeeding cautions.

The evidence for effectiveness on most conditions is insufficient, so talk to your pharmacist about what you're hoping this will do and whether the science backs it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 24, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about David Winston's AF Compound, straight from the product label.

Brand Herbalist & Alchemist
Barcode (UPC) 667056100063
Net contents 2 fl. Oz.; 60 mL
Market status On market
Date entered into DSLD Sep 24, 2019
DSLD ID 206982
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher, Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for David Winston's AF Compound by Herbalist & Alchemist, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 mL
Maximum serving Sizes:
2 mL
Servings per container
30
UPC/BARCODE
667056100063
IngredientAmount% DV
Proprietary Blend2 mL--
Black Walnut extract0 NP--
Yellow Root extract0 NP--
Spilanthes extract0 NP--
Myrrh extract0 NP--
Usnea lichen extract0 NP--
Cardamom extract0 NP--

Other ingredients: Ethyl Alcohol, distilled Water, Vegetable Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Supports normal systemic flora

FDA Statement of Identity

Herbal Supplement

Suggested/Recommended/Usage/Directions

Suggested use: 30-40 drops (1.5-2 mL) in juice or water. Take 3 times per day. Shake well before using.

Precautions

Contraindications: Do not use during pregnancy or lactation.

Keep out of children's reach

FDA Disclaimer Statement

This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

OK

Formula

OK

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

David Winston's AF Compound by Herbalist & Alchemist label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

David Winston's AF Compound label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in David Winston's AF Compound by Herbalist & Alchemist

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

2 mL per serving

Other (inactive) ingredients: Ethyl Alcohol, Distilled Water, Vegetable Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

David Winston's AF Compound by Herbalist & Alchemist Drug Interactions

Want to check YOUR meds against David Winston's AF Compound?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
88Drugs
88 Moderate

Ingredients driving the most interactions

Myrrh extract 88

Individual Drug Interactions

The ingredients in David Winston's AF Compound interact with 88 drugs. Click any drug to see the details.

1 of the 6 ingredients in David Winston's AF Compound interact with drugs. Each result below shows which ingredient is responsible. Myrrh extract

Each ingredient & the kinds of drugs it affects

For each ingredient in David Winston's AF Compound with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Myrrh extract2 drug types · 88 drugs

Antidiabetes Drugs

Theoretically, myrrh might increase the risk of hypoglycemia when taken with antidiabetes drugs.
In vitro and animal research suggests that myrrh has hypoglycemic effects.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, myrrh might decrease the effectiveness of warfarin.
In one case, a patient who was previously stable on warfarin had a significant decline in international normalized ratio (INR) following consumption of an aqueous extract of myrrh.

Likelihood Possible Evidence D
Myrrh extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for David Winston's AF Compound, from the product label.

Herbalist & Alchemist

See all Herbalist & Alchemist products
Name
Herbalist & Alchemist, Inc.
City
Washington
State
NJ
ZipCode
07882
Phone Number
800-611-8235
Web Address
www.herbalist-alchemist.com
Pharmacist Counseling Corner

David Winston's AF Compound by Herbalist & Alchemist: Common Questions

Does David Winston's AF Compound by Herbalist & Alchemist interact with any medications?
Yes. Based on its ingredients, David Winston's AF Compound has a known interaction with 88 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
David Winston's AF Compound contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
Black Walnut, Myrrh, and Usnea lichen all advise against use in pregnancy or while breastfeeding — Myrrh in particular may stimulate the uterus. Cardamom is likely safe while breastfeeding, but we don't have safety data on the others. Talk to your pharmacist or doctor for personalized advice before taking this product.
What is myrrh supposed to do?
Myrrh is traditionally used for various conditions, but the evidence we have rates it either insufficient or likely ineffective for most of them. It's generally considered fine for short-term topical or mouth-rinse use, though its oral safety isn't well established.
Does this product have any fillers or other ingredients I should know about?
The inactive ingredients are ethyl alcohol, distilled water, and vegetable glycerin. The product is a liquid, so these are the carriers for the six active extracts.
What are the side effects I should watch for?
Black Walnut's leaf, bark, and hull can cause gastrointestinal upset. Myrrh may cause diarrhea at higher doses. Usnea lichen's usnic acid has been linked to liver damage when taken orally. Cardamom is generally well tolerated, though one person in a trial reported mild skin inflammation.
Is Black Walnut safe to use long-term?
The data show that Black Walnut may be acceptable short-term for most adults, but human safety data are limited and long-term use hasn't been well studied. Don't take it long-term without talking to your pharmacist or doctor.
What about tree nut allergies — is black walnut safe if I'm allergic to tree nuts?
Tree nuts, including black walnuts, can cause allergic reactions in sensitive individuals. If you have a tree nut allergy, avoid this product and discuss it with your pharmacist before taking it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

David Winston's AF Compound label
Go deeper

The Full Monographs Behind David Winston's AF Compound’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Black Walnut

Black walnut is a tree whose green hulls are traditionally used as a natural antiparasitic and digestive remedy, but solid human evidence for these uses is lacking. It contains a compound ca...

Read the full Black Walnut monograph → Herb & supplement monograph

Myrrh

Interacts with 88 drugs

Myrrh is a fragrant gum resin from Commiphora trees that has long been used in mouthwashes, throat remedies, and skin care. Modern evidence for most of its uses is limited and comes mostly f...

Read the full Myrrh monograph → Herb & supplement monograph

Usnea

Usnea is a lichen used in traditional herbal medicine, mainly for sore throats, skin infections, and as a general antimicrobial. Laboratory studies suggest its main compound, usnic acid, can...

Read the full Usnea monograph → Herb & supplement monograph

Cardamom

Cardamom is a popular cooking spice that has long been used in traditional medicine for digestion and fresh breath. As a food, it is generally safe for most people, but high-dose supplements...

Read the full Cardamom monograph →
Sources

Sources & How We Checked

David Winston's AF Compound's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 23 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Black Walnut 3 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Food and Drug Administration. Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA); Public Law 108-282, Title II. Accessed on May 19, 2021. Available at: https://www.fda.gov/food/food-allergensgluten-free-guidance-documents-regulatory-infor

See these in context on the Black Walnut monograph →

Myrrh 8 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  4. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  5. Al Faraj S. Antagonism of the anticoagulant effect of warfarin caused by the use of Commiphora molmol as a herbal medication: a case report. Ann Trop Med Parasitol 2005;99:219-20.
  6. Al-Jaroudi D, Kaddour O, Al-Amin N. Risks of myrrh use in pregnancy. JBRA Assist Reprod 2016;20(4):257-8.
  7. Xu YY, Li L, Xuan L, Guan K. Patch test diagnosis of non-immediate cutaneous reaction to myrrh following oral intake of a traditional Chinese medicine decoction. Contact Dermatitis. 2019;80(2):135-136. PubMed
  8. Al-Romaiyan A, Huang GC, Jones P, Persaud S. Commiphora myrrha stimulates insulin secretion from mouse and human islets of Langerhans. J Ethnopharmacol. 2021 Jan 10;264:113075. PubMed

See these in context on the Myrrh monograph →

Usnea 10 references
  1. Favreau JT, Ryu Ml, Braunstein G, et al. Severe hepatotoxicity associated with the dietary supplement LipoKinetix. Ann Intern Med 2002;136:590-5. PubMed
  2. Ingolfsdottir K. Usnic acid. Phytochemistry 2002;61:729-36.
  3. Scirpa, P., Scambia, G., Masciullo, V., Battaglia, F., Foti, E., Lopez, R., Villa, P., Malecore, M., and Mancuso, S. [A zinc sulfate and usnic acid preparation used as post-surgical adjuvant therapy in genital lesions by Human Papillomavirus]. Minerva Gin
  4. Mitchell, J. C. Allergy to lichens. Allergic contact dermatitis from usnic acid produced by lichenized fungi. Arch Dermatol 1965;92(2):142-146.
  5. Durazo, F. A., Lassman, C., Han, S. H., Saab, S., Lee, N. P., Kawano, M., Saggi, B., Gordon, S., Farmer, D. G., Yersiz, H., Goldstein, R. L., Ghobrial, M., and Busuttil, R. W. Fulminant liver failure due to usnic acid for weight loss. Am.J Gastroenterol. PubMed
  6. Neff, G. W., Reddy, K. R., Durazo, F. A., Meyer, D., Marrero, R., and Kaplowitz, N. Severe hepatotoxicity associated with the use of weight loss diet supplements containing ma huang or usnic acid. J Hepatol. 2004;41(6):1062-1064. PubMed
  7. Hsu, L. M., Huang, Y. S., Chang, F. Y., and Lee, S. D. 'Fat burner' herb, usnic Acid, induced acute hepatitis in a family. J Gastroenterol.Hepatol. 2005;20(7):1138-1139. PubMed
  8. Arneborn, P., Jansson, A., and Bottiger, Y. [Acute hepatitis in a woman after intake of slimming pills bought via Internet]. Lakartidningen 7-11-2005;102(28-29):2071-2072.
  9. Sanchez, W., Maple, J. T., Burgart, L. J., and Kamath, P. S. Severe hepatotoxicity associated with use of a dietary supplement containing usnic acid. Mayo Clin Proc 2006;81(4):541-544. PubMed
  10. Rafanelli, S., Bacchilega, R., Stanganelli, I., and Rafanelli, A. Contact dermatitis from usnic acid in vaginal ovules. Contact Dermatitis 1995;33(4):271-272. PubMed

See these in context on the Usnea monograph →

Cardamom 2 references
  1. Mobacken, H. and Fregert, S. Allergic contact dermatitis from cardamom. Contact Dermatitis 1975;1(3):175-176. PubMed
  2. Aghasi M, Koohdani F, Qorbani M, et al. Beneficial effects of green cardamom on serum SIRT1, glycemic indices and triglyceride levels in patients with type 2 diabetes mellitus: a randomized double-blind placebo controlled clinical trial. J Sci Food Agri PubMed

See these in context on the Cardamom monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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