Interactions on record — worth a quick check against your medications. Based on 4 of 9 ingredients. Check your meds →
Dietary supplement

Digest Solve 24/7 Ingredients & Drug Interactions

by American BioSciences

Capsule Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Digest Solve 24/7 is a dietary supplement by American BioSciences with 9 active ingredients. Its ingredients are commonly taken for lactose intolerance, gas and bloating after dairy, diarrhea from dairy foods.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bifidobacterium Longum. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Digest Solve 24/7 by American BioSciences

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 9 of its 9 active ingredients.
  • “BioCore(R) Dairy Ultra” is listed as a grouped ingredient — the label gives one combined amount (108 mg) without saying how much of each component you get.
  • “BioCore(R) Carbo” is listed as a grouped ingredient — the label gives one combined amount (43 mg) without saying how much of each component you get.

Digest Solve 24/7 contains 9 active ingredients: four digestive enzymes (amylase, glucoamylase, invertase, and lipase) that help break down carbohydrates, proteins, and fats; lactase, which helps digest lactose; diastase and protease for additional starch and protein breakdown; and Bifidobacterium longum, a live probiotic bacterium meant to support gut health. The remaining ingredients are inactive fillers and binding agents that give the capsule its structure.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: support digestion and stomach function.
  • We looked for evidence on: Dyspepsia, Diarrhea, Constipation, Irritable bowel syndrome (IBS), Lactose intolerance, Antibiotic-associated diarrhea — and 3 related terms.
  • The strongest evidence on file: Lactase is rated "Effective" for Lactose intolerance (Natural Medicines).
  • Also on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia.
  • Also on file: Bifidobacterium Longum is rated "Insufficient Reliable Evidence To Rate" for Antibiotic-associated diarrhea, Constipation, Diarrhea, Irritable bowel syndrome (IBS), and more.

The evidence for most ingredients in this product is not established in our data. Lactase is rated effective for lactose intolerance — it genuinely helps your body digest milk sugar if you're intolerant.

For the other digestive enzymes (amylase, lipase, protease, and diastase) and Bifidobacterium longum, the evidence for conditions like indigestion (dyspepsia), inflammatory bowel disease, or anxiety is insufficient to rate. None of these ingredients have a proven effectiveness rating in the data we hold.

The evidence, ingredient by ingredient Lactase Lipase Proteolytic Enzymes (proteases) Bifidobacterium Longum

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactase is generally well tolerated and likely safe in pregnancy and while breastfeeding, though you should check with your doctor before regular use during pregnancy. A rare allergic reaction to lactase has been reported in occupational exposure, so stop and tell your doctor if you develop any allergic symptoms.

Lipase and protease are generally well tolerated in healthy adults, but lipase should be avoided in premature infants due to rare serious bowel complications (necrotizing enterocolitis). There is limited pregnancy and breastfeeding data for lipase and protease — talk with your doctor before using them if you're pregnant or nursing.

Bifidobacterium longum is possibly safe in pregnancy and is generally well tolerated in healthy people, though it carries a rare risk of serious bloodstream infection in critically ill or immune-compromised patients and in premature infants. Rare mild side effects include abdominal discomfort, flatulence, constipation, and dry cough.

Side effects, ingredient by ingredient Lactase Lipase Proteolytic Enzymes (proteases) Bifidobacterium Longum

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 4 matched ingredients can interact with medications — Bifidobacterium Longum.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start Digest Solve 24/7, double-check with your doctor or pharmacist if you take any antibiotic drugs — Bifidobacterium longum may become less effective if taken at the same time. No other interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a multi-enzyme digestive supplement with one probiotic ingredient, best suited for people seeking lactose digestion support or general enzyme supplementation. If you take antibiotics, you'll need to separate their timing from this product — talk with your doctor or pharmacist about how to schedule them.

Pregnant or breastfeeding women, and anyone with serious immune or digestive conditions, should check with their own healthcare provider before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Digest Solve 24/7, straight from the product label.

Brand American BioSciences
Barcode (UPC) 678226032909
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Apr 25, 2013
DSLD ID 20500
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Digest Solve 24/7 by American BioSciences, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
678226032909
IngredientAmount% DV
Amylase3526 DU--
Glucoamylase11.8 AGU--
Invertase473 SU--
Lactase1000 ALU--
Lipase600 FIP--
Diastase3870 DP--
Protease630 BLGU--
BioCore(R) Dairy Ultra108 mg--
Bifidobacterium Longum75 mg--
BioCore(R) Carbo43 mg--
A proprietary blend of200 mg--

Other ingredients: Cellulose, Tapioca Starch, Powder, Silicon Dioxide, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage

No need to refrigerate

Store in a cool, dry place.

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

BB536(R) is a registered trademark of Morinaga Milk Industry Co., Ltd. BioCore(R) is a registered trademark of National Enzyme Company

DIGESTSolve 24/7(TM) Works round the clock to help support digestion and optimal stomach function.*

(c)2011 American BioSciences, Inc.

Formula

DIGESTSolve 24/7, contains a combination of Bifidus BB536 Probiotic, BioCore(R) Carbo & Dairy Digestive Enzymes and the gut soothing herbs, Chamomile and Fennel, that work synergistically to enhance digestion and promote healthy stomach function.*

General Statements

DIGESTSolve 24/7 also helps to support healthy intestinal flora and immune system balance.*

Nature & Science For Better Health

Digestion and Stomach Support* All Day~All Night~All Natural -Probiotic and digestive enzyme combination -Addresses carbohydrate and dairy digestion challenges that may cause gas, bloating and irregularity*

Suggested/Recommended/Usage/Directions

Suggested Use: Take 1 capsule just prior to eating each meal, typically 3 capsules per day

Precautions

Do not purchase if outer seal is broken or missing. Do not use if you are hypersensitive to any ingredient in this formula.

Consult with a physician prior to use of this product if you are pregnant, nursing, or have any existing medical condition.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

LABDS-90B1

Seals/Symbols

GLUTEN FREE

See for yourself

Digest Solve 24/7 by American BioSciences label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Digest Solve 24/7 by American BioSciences

These are the 9 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

BioCore(R) Dairy Ultra

108 mg per serving

Bifidobacterium Longum

Interacts with
182 drugs
75 mg per serving

Bifidobacterium longum is a 'friendly' bacterium found naturally in the human gut and used as a probiotic. It is generally well tolerated and is most...

Bifidobacterium Longum monograph & interactions

BioCore(R) Carbo

43 mg per serving
  • › Amylase
  • › Glucoamylase
  • › Invertase
  • › Diastase

A proprietary blend of

200 mg per serving Form: Chamomile, Fennel

Other (inactive) ingredients: Cellulose, Tapioca Starch, Powder, Silicon Dioxide, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Digest Solve 24/7 by American BioSciences Drug Interactions

Want to check YOUR meds against Digest Solve 24/7?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Digest Solve 24/7 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bifidobacterium Longum1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B. longum.
Since B. longum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. longum preparations by at least 2 hours.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Digest Solve 24/7, from the product label.

American BioSciences

See all American BioSciences products
Name
American BioSciences, Inc.
City
Blauvelt
State
NY
ZipCode
10913
Phone Number
888-884-7770
Web Address
www.americanbiosciences.com
Pharmacist Counseling Corner

Digest Solve 24/7 by American BioSciences: Common Questions

Does Digest Solve 24/7 by American BioSciences interact with any medications?
Yes. Based on its ingredients, Digest Solve 24/7 has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Digest Solve 24/7 contains 9 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help with my lactose intolerance?
Yes — lactase, one of the active ingredients, is rated effective for lactose intolerance. It helps your body digest milk sugar. The other enzymes in the blend are intended to aid general digestion of carbohydrates, fats, and proteins, but their effectiveness for digestive complaints hasn't been established in our data.
Can I take this with antibiotics?
You can take both, but not at the same time. The Bifidobacterium longum in this product is a live organism that antibiotics will kill, which defeats the purpose of the probiotic. Ask your pharmacist or doctor about spacing them apart — typically several hours between doses works best.
Is it safe to take while I'm pregnant?
Lactase and Bifidobacterium longum are possibly safe or likely safe in pregnancy, but there is limited data on lipase and protease during pregnancy. Talk with your doctor or pharmacist before starting it — that way you can get personalized advice based on your health.
What does the probiotic ingredient do?
Bifidobacterium longum is a live beneficial bacterium meant to support gut health, but the evidence for what it actually does — whether for digestive complaints, immunity, mood, or other conditions — isn't established in our data. It's generally well tolerated in healthy people.
Are there any side effects?
Most people tolerate these ingredients well. Rare side effects include mild abdominal discomfort, bloating, flatulence, or constipation from the enzymes or probiotic. A very rare allergic reaction to lactase has been reported. Stop and contact your healthcare provider if you develop any unusual symptoms.
What are all the ingredients I'm getting?
You get four digestive enzymes (amylase, glucoamylase, invertase, lipase), lactase for milk sugar digestion, two other enzymes (diastase and protease), the probiotic Bifidobacterium longum, and inactive fillers like cellulose and magnesium stearate. One proprietary enzyme blend is also included.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Digest Solve 24/7 is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Digest Solve 24/7 label
Sources

Sources & How We Checked

Digest Solve 24/7's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 26 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Bifidobacterium Longum 21 references
  1. Ha GY, Yang CH, Kim H, Chong Y. Case of sepsis caused by Bifidobacterium longum. J Clin Microbiol 1999;37:1227-8.
  2. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  3. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  4. Rautava S, Kainonen E, Salminen S, Isolauri E. Maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant. J Allergy Clin Immunol. 2012;130(6):1355-60. PubMed
  5. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  6. Pellonperä O, Vahlberg T, Mokkala K, et al. Weight gain and body composition during pregnancy: a randomised pilot trial with probiotics and/or fish oil. Br J Nutr. 2020 Nov 4:1-11. PubMed
  7. Pellonperä O, Mokkala K, Houttu N, et al. Efficacy of fish oil and/or probiotic intervention on the incidence of gestational diabetes mellitus in an at-risk group of overweight and obese women: A randomized, placebo-controlled, double-blind clinical trial PubMed
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
  10. Enomoto T, Sowa M, Nishimori K, et al. Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota. Allergol Int 2014;63(4):575-85. PubMed
  11. US Food and Drug Administration (FDA). Dear Healthcare Provider Letter: Warning Regarding Use of Probiotics in Preterm Infants. September 2023. Available at: https://www.fda.gov/media/172606/download?attachment. Accessed November 1, 2023.
  12. Pillai A, Tan J, Paquette V, Panczuk J. Does probiotic bacteremia in premature infants impact clinically relevant outcomes? A case report and updated review of literature. Clin Nutr ESPEN. 2020;39:255-259. PubMed
  13. Sabaté JM, Iglicki F. Effect of Bifidobacterium longum 35624 on disease severity and quality of life in patients with irritable bowel syndrome. World J Gastroenterol 2022;28(7):732-744.
  14. Malaguarnera M, Greco F, Barone G, Gargante MP, Malaguarnera M, Toscano MA. Bifidobacterium longum with fructo-oligosaccharide (FOS) treatment in minimal hepatic encephalopathy: a randomized, double-blind, placebo-controlled study. Dig Dis Sci 2007;52(11) PubMed
  15. Zbinden A, Zbinden R, Berger C, Arlettaz R. Case series of Bifidobacterium longum bacteremia in three preterm infants on probiotic therapy. Neonatology 2015;107(1):56-9.
  16. Tamaki H, Nakase H, Inoue S, et al. Efficacy of probiotic treatment with Bifidobacterium longum 536 for induction of remission in active ulcerative colitis: A randomized, double-blinded, placebo-controlled multicenter trial. Dig Endosc 2016;28(1):67-74.
  17. Bertelli C, Pillonel T, Torregrossa A, et al. Bifidobacterium longum bacteremia in preterm infants receiving probiotics. Clin Infect Dis 2015;60(6):924-7. PubMed
  18. Esaiassen E, Cavanagh P, Hjerde E, Simonsen GS, Støen R, Klingenberg C. Bifidobacterium longum subspecies infantis bacteremia in 3 extremely preterm infants receiving probiotics. Emerg Infect Dis 2016;22(9):1664-6.
  19. Tena D, Losa C, Medina MJ, Sáez-Nieto JA. Peritonitis caused by Bifidobacterium longum: case report and literature review. Anaerobe 2014;27:27-30. PubMed
  20. Sangkanjanavanich S, Pradubpongsa P, Mitthamsiri W, Sangasapaviliya A, Boonpiyathad T. Bifidobacterium infantis 35624 efficacy in patients with uncontrolled asthma: A randomized placebo-controlled trial. Ann Allergy Asthma Immunol 2022;129(6):790-792. PubMed
  21. Wilson HL, Ong CW. Bifidobacterium longum vertebrodiscitis in a patient with cirrhosis and prostate cancer. Anaerobe 2017;47:47-50. PubMed

See these in context on the Bifidobacterium Longum monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring