Digest Solve 24/7 Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Digest Solve 24/7 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Digest Solve 24/7 is a dietary supplement by American BioSciences with 9 active ingredients. Its ingredients are commonly taken for lactose intolerance, gas and bloating after dairy, diarrhea from dairy foods.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bifidobacterium Longum. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Digest Solve 24/7 by American BioSciences
Ask about any prescription or over-the-counter medication and we check it for interactions with Digest Solve 24/7 by American BioSciences — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Digest Solve 24/7 by American BioSciences
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Digest Solve 24/7 contains 9 active ingredients: four digestive enzymes (amylase, glucoamylase, invertase, and lipase) that help break down carbohydrates, proteins, and fats; lactase, which helps digest lactose; diastase and protease for additional starch and protein breakdown; and Bifidobacterium longum, a live probiotic bacterium meant to support gut health. The remaining ingredients are inactive fillers and binding agents that give the capsule its structure.
Does it work?
Strong evidence
The evidence for most ingredients in this product is not established in our data. Lactase is rated effective for lactose intolerance — it genuinely helps your body digest milk sugar if you're intolerant.
For the other digestive enzymes (amylase, lipase, protease, and diastase) and Bifidobacterium longum, the evidence for conditions like indigestion (dyspepsia), inflammatory bowel disease, or anxiety is insufficient to rate. None of these ingredients have a proven effectiveness rating in the data we hold.
How safe is it?
Well-documented data
Lactase is generally well tolerated and likely safe in pregnancy and while breastfeeding, though you should check with your doctor before regular use during pregnancy. A rare allergic reaction to lactase has been reported in occupational exposure, so stop and tell your doctor if you develop any allergic symptoms.
Lipase and protease are generally well tolerated in healthy adults, but lipase should be avoided in premature infants due to rare serious bowel complications (necrotizing enterocolitis). There is limited pregnancy and breastfeeding data for lipase and protease — talk with your doctor before using them if you're pregnant or nursing.
Bifidobacterium longum is possibly safe in pregnancy and is generally well tolerated in healthy people, though it carries a rare risk of serious bloodstream infection in critically ill or immune-compromised patients and in premature infants. Rare mild side effects include abdominal discomfort, flatulence, constipation, and dry cough.
Meds to double-check
Moderate interaction found
Before you start Digest Solve 24/7, double-check with your doctor or pharmacist if you take any antibiotic drugs — Bifidobacterium longum may become less effective if taken at the same time. No other interactions are documented for the ingredients we could check.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This is a multi-enzyme digestive supplement with one probiotic ingredient, best suited for people seeking lactose digestion support or general enzyme supplementation. If you take antibiotics, you'll need to separate their timing from this product — talk with your doctor or pharmacist about how to schedule them.
Pregnant or breastfeeding women, and anyone with serious immune or digestive conditions, should check with their own healthcare provider before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2013.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Digest Solve 24/7, straight from the product label.
| Brand | American BioSciences |
|---|---|
| Barcode (UPC) | 678226032909 |
| Net contents | 90 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Apr 25, 2013 |
| DSLD ID | 20500 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Digest Solve 24/7 by American BioSciences, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Amylase | 3526 DU | -- |
| Glucoamylase | 11.8 AGU | -- |
| Invertase | 473 SU | -- |
| Lactase | 1000 ALU | -- |
| Lipase | 600 FIP | -- |
| Diastase | 3870 DP | -- |
| Protease | 630 BLGU | -- |
| BioCore(R) Dairy Ultra | 108 mg | -- |
| Bifidobacterium Longum | 75 mg | -- |
| BioCore(R) Carbo | 43 mg | -- |
| A proprietary blend of | 200 mg | -- |
Other ingredients: Cellulose, Tapioca Starch, Powder, Silicon Dioxide, Magnesium Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage
No need to refrigerate
Store in a cool, dry place.
FDA Statement of Identity
Dietary Supplement
Brand IP Statement(s)
BB536(R) is a registered trademark of Morinaga Milk Industry Co., Ltd. BioCore(R) is a registered trademark of National Enzyme Company
DIGESTSolve 24/7(TM) Works round the clock to help support digestion and optimal stomach function.*
(c)2011 American BioSciences, Inc.
Formula
DIGESTSolve 24/7, contains a combination of Bifidus BB536 Probiotic, BioCore(R) Carbo & Dairy Digestive Enzymes and the gut soothing herbs, Chamomile and Fennel, that work synergistically to enhance digestion and promote healthy stomach function.*
General Statements
DIGESTSolve 24/7 also helps to support healthy intestinal flora and immune system balance.*
Nature & Science For Better Health
Digestion and Stomach Support* All Day~All Night~All Natural -Probiotic and digestive enzyme combination -Addresses carbohydrate and dairy digestion challenges that may cause gas, bloating and irregularity*
Suggested/Recommended/Usage/Directions
Suggested Use: Take 1 capsule just prior to eating each meal, typically 3 capsules per day
Precautions
Do not purchase if outer seal is broken or missing. Do not use if you are hypersensitive to any ingredient in this formula.
Consult with a physician prior to use of this product if you are pregnant, nursing, or have any existing medical condition.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General
LABDS-90B1
Seals/Symbols
GLUTEN FREE
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Digest Solve 24/7 by American BioSciences label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Digest Solve 24/7 by American BioSciences
These are the 9 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Bifidobacterium Longum
Interacts with182 drugs
Bifidobacterium longum is a 'friendly' bacterium found naturally in the human gut and used as a probiotic. It is generally well tolerated and is most...
Bifidobacterium Longum monograph & interactionsBioCore(R) Carbo
- › Amylase
- › Glucoamylase
- › Invertase
- › Diastase
A proprietary blend of
Other (inactive) ingredients: Cellulose, Tapioca Starch, Powder, Silicon Dioxide, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
Digest Solve 24/7 by American BioSciences Drug Interactions
HelloPharmacist Interaction Report
Digest Solve 24/7 by American BioSciences contains one ingredient with documented interactions: Bifidobacterium longum, a probiotic that can reduce the effectiveness of antibiotic drugs.
The risk is Moderate — antibiotics may kill off the live organisms in the probiotic, making the supplement less effective.
Read the full breakdown — every affected drug type, severity by severity
Lactase, lipase, and protease are all checked and show no interactions in our data. We could not verify interaction data for amylase, glucoamylase, invertase, diastase, or the proprietary blend components — they were not checked against the medication database.
Although only one ingredient has documented interactions, the medication count affected is substantial. Altogether, these interactions span 182 individual medications.
If you take any antibiotic or other prescription drugs, run your exact medications through the checker on this page before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Digest Solve 24/7?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Digest Solve 24/7 interact with 182 drugs. Click any drug to see the details.
1 of the 9 ingredients in Digest Solve 24/7 interact with drugs. Each result below shows which ingredient is responsible. Bifidobacterium Longum
AmikacinAmikin, Arikayce
How Amikacin interacts with Digest Solve 24/7 — through 1 ingredient. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Amikacin interactionAmoxicillinAmix, Amoram, Amoxident, Amoxil Capsules, Amoxil Injection, Galenamox +3 more
How Amoxicillin interacts with Digest Solve 24/7 — through 1 ingredient. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Amoxicillin interactionAmoxicillin VeterinaryBiomox
How Amoxicillin Veterinary interacts with Digest Solve 24/7 — through 1 ingredient. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Amoxicillin Veterinary interactionAmoxicillin, Clavulanate PotassiumAugmentin, Augmentin '125/31 SF', Augmentin '250/62 SF', Augmentin XR, Augmentin-Duo 400/57, Clavulin
How Amoxicillin, Clavulanate Potassium interacts with Digest Solve 24/7 — through 1 ingredient. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Amoxicillin, Clavulanate Potassium interactionAmoxicillin, Omeprazole Magnesium, RifabutinTalicia
How Amoxicillin, Omeprazole Magnesium, Rifabutin interacts with Digest Solve 24/7 — through 1 ingredient. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionAmphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with Digest Solve 24/7 — through 1 ingredient. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Amphotericin, Tetracycline interactionAmpicillinOmnipen, Omnipen-N, Penbritin, Principen, Rimacillin
How Ampicillin interacts with Digest Solve 24/7 — through 1 ingredient. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Ampicillin interactionAmpicillin, SulbactamUnasyn
How Ampicillin, Sulbactam interacts with Digest Solve 24/7 — through 1 ingredient. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Ampicillin, Sulbactam interactionAvibactam Sodium, CeftazidimeAvycaz
How Avibactam Sodium, Ceftazidime interacts with Digest Solve 24/7 — through 1 ingredient. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Avibactam Sodium, Ceftazidime interactionAzithromycinAzasite, Zithromax, Zmax
How Azithromycin interacts with Digest Solve 24/7 — through 1 ingredient. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Azithromycin interactionAztreonamAzactam
How Aztreonam interacts with Digest Solve 24/7 — through 1 ingredient. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Aztreonam interactionBacampicillinPenglobe
How Bacampicillin interacts with Digest Solve 24/7 — through 1 ingredient. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Bacampicillin interactionBacitracinBaci-IM, Baciguent, Bacitracin Ointment
How Bacitracin interacts with Digest Solve 24/7 — through 1 ingredient. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Bacitracin interactionBenznidazoleBenznidazole
How Benznidazole interacts with Digest Solve 24/7 — through 1 ingredient. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Benznidazole interactionBismuth Subsalicylate, Metronidazole, TetracyclineHelidac
How Bismuth Subsalicylate, Metronidazole, Tetracycline interacts with Digest Solve 24/7 — through 1 ingredient. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionCapreomycinCapastat
How Capreomycin interacts with Digest Solve 24/7 — through 1 ingredient. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Capreomycin interactionCarbenicillin Indanyl SodiumGeocillin
How Carbenicillin Indanyl Sodium interacts with Digest Solve 24/7 — through 1 ingredient. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Carbenicillin Indanyl Sodium interactionCefaclorCeclor, Ceclor CD
How Cefaclor interacts with Digest Solve 24/7 — through 1 ingredient. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefaclor interactionCefadroxilCef-Tab, Duricef, Ultracef
How Cefadroxil interacts with Digest Solve 24/7 — through 1 ingredient. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefadroxil interactionCefamandoleMandol
How Cefamandole interacts with Digest Solve 24/7 — through 1 ingredient. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefamandole interactionCefazolinAncef
How Cefazolin interacts with Digest Solve 24/7 — through 1 ingredient. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefazolin interactionCefdinirOmnicef
How Cefdinir interacts with Digest Solve 24/7 — through 1 ingredient. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefdinir interactionCefditoren PivoxilSpectracef
How Cefditoren Pivoxil interacts with Digest Solve 24/7 — through 1 ingredient. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefditoren Pivoxil interactionCefepimeMaxipime
How Cefepime interacts with Digest Solve 24/7 — through 1 ingredient. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefepime interactionCefiderocol Sulfate TosylateFetroja
How Cefiderocol Sulfate Tosylate interacts with Digest Solve 24/7 — through 1 ingredient. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefiderocol Sulfate Tosylate interactionCefiximeSuprax
How Cefixime interacts with Digest Solve 24/7 — through 1 ingredient. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefixime interactionCefmetazoleZefazone
How Cefmetazole interacts with Digest Solve 24/7 — through 1 ingredient. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefmetazole interactionCefonicidMonocid
How Cefonicid interacts with Digest Solve 24/7 — through 1 ingredient. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefonicid interactionCefoperazoneCefobid
How Cefoperazone interacts with Digest Solve 24/7 — through 1 ingredient. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefoperazone interactionCefotaximeClaforan
How Cefotaxime interacts with Digest Solve 24/7 — through 1 ingredient. Tap an ingredient for the detail:
Bifidobacterium LongumAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B.
Read the full Bifidobacterium Longum + Cefotaxime interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Digest Solve 24/7 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Bifidobacterium Longum
Antibiotic Drugs
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B. longum.
Since B. longum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. longum preparations by at least 2 hours.
Brand information
Manufacturer and brand details for Digest Solve 24/7, from the product label.
American BioSciences
See all American BioSciences products- Name
- American BioSciences, Inc.
- City
- Blauvelt
- State
- NY
- ZipCode
- 10913
- Phone Number
- 888-884-7770
- Web Address
- www.americanbiosciences.com
Digest Solve 24/7 by American BioSciences: Common Questions
Does Digest Solve 24/7 by American BioSciences interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this help with my lactose intolerance?
Can I take this with antibiotics?
Is it safe to take while I'm pregnant?
What does the probiotic ingredient do?
Are there any side effects?
What are all the ingredients I'm getting?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Digest Solve 24/7 is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Digest Solve 24/7’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Lactase
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can reduce gas, bloating, cramping, and diarrhe...
Read the full Lactase monograph → Herb & supplement monographLipase
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...
Read the full Lipase monograph → Herb & supplement monographProteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph → Herb & supplement monographBifidobacterium Longum
Interacts with 182 drugsBifidobacterium longum is a 'friendly' bacterium found naturally in the human gut and used as a probiotic. It is generally well tolerated and is most studied for digestive issues, though evi...
Read the full Bifidobacterium Longum monograph →Sources & How We Checked
Digest Solve 24/7's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 26 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lactase 1 reference
- Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Bifidobacterium Longum 21 references
- Ha GY, Yang CH, Kim H, Chong Y. Case of sepsis caused by Bifidobacterium longum. J Clin Microbiol 1999;37:1227-8.
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
- Rautava S, Kainonen E, Salminen S, Isolauri E. Maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant. J Allergy Clin Immunol. 2012;130(6):1355-60. PubMed
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Pellonperä O, Vahlberg T, Mokkala K, et al. Weight gain and body composition during pregnancy: a randomised pilot trial with probiotics and/or fish oil. Br J Nutr. 2020 Nov 4:1-11. PubMed
- Pellonperä O, Mokkala K, Houttu N, et al. Efficacy of fish oil and/or probiotic intervention on the incidence of gestational diabetes mellitus in an at-risk group of overweight and obese women: A randomized, placebo-controlled, double-blind clinical trial PubMed
- Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
- Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
- Enomoto T, Sowa M, Nishimori K, et al. Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota. Allergol Int 2014;63(4):575-85. PubMed
- US Food and Drug Administration (FDA). Dear Healthcare Provider Letter: Warning Regarding Use of Probiotics in Preterm Infants. September 2023. Available at: https://www.fda.gov/media/172606/download?attachment. Accessed November 1, 2023.
- Pillai A, Tan J, Paquette V, Panczuk J. Does probiotic bacteremia in premature infants impact clinically relevant outcomes? A case report and updated review of literature. Clin Nutr ESPEN. 2020;39:255-259. PubMed
- Sabaté JM, Iglicki F. Effect of Bifidobacterium longum 35624 on disease severity and quality of life in patients with irritable bowel syndrome. World J Gastroenterol 2022;28(7):732-744.
- Malaguarnera M, Greco F, Barone G, Gargante MP, Malaguarnera M, Toscano MA. Bifidobacterium longum with fructo-oligosaccharide (FOS) treatment in minimal hepatic encephalopathy: a randomized, double-blind, placebo-controlled study. Dig Dis Sci 2007;52(11) PubMed
- Zbinden A, Zbinden R, Berger C, Arlettaz R. Case series of Bifidobacterium longum bacteremia in three preterm infants on probiotic therapy. Neonatology 2015;107(1):56-9.
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See these in context on the Bifidobacterium Longum monograph →
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