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Dietary supplement

Digestive Health Probiotic Ingredients & Drug Interactions

by Meijer

Digestive Health Probiotic label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Digestive Health Probiotic against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Digestive Health Probiotic is a dietary supplement by Meijer with 1 active ingredient. Its ingredients are commonly taken for digestive health and balance, diarrhea (including antibiotic-related), vaginal yeast and bacterial infections.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacillus acidophilus LA-14. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Digestive Health Probiotic by Meijer

Ask about any prescription or over-the-counter medication and we check it for interactions with Digestive Health Probiotic by Meijer — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Digestive Health Probiotic by Meijer

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

This single-ingredient probiotic contains Lactobacillus acidophilus LA-14, a live beneficial bacterium intended to support digestive health. The capsule itself is made with cellulose, water, magnesium stearate, silica, and calcium stearate — all inactive ingredients that help hold the capsule together and keep the probiotic stable.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: digestive health and healthy intestinal flora balance.
  • We looked for evidence on: Antibiotic-associated diarrhea, Clostridioides difficile infection, Constipation, Inflammatory bowel disease (IBD), Irritable bowel syndrome (IBS), Lactose intolerance — and 4 related terms.
  • The strongest evidence on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Irritable bowel syndrome (IBS).
  • Also on file: Lactobacillus Acidophilus is rated "Insufficient Reliable Evidence To Rate" for Constipation, Inflammatory bowel disease (IBD), Radiation-induced diarrhea, Lactose intolerance, and more.

L. acidophilus is possibly effective for irritable bowel syndrome, H. pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis based on available evidence. It appears possibly ineffective for atopic disease.

For acute respiratory distress syndrome, we don't have enough reliable evidence to rate it either way. Talk with your doctor about whether this probiotic fits your particular digestive concern.

The evidence, ingredient by ingredient Lactobacillus Acidophilus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactobacillus acidophilus is generally well tolerated in healthy adults and children. That said, since these are live organisms, there's a small theoretical risk of infection in certain patients — including rare cases of bacteremia or other serious infections, though most occur in people with underlying conditions.

Some folks taking L. acidophilus with other probiotics report mild gastrointestinal side effects like bloating, gas, abdominal discomfort, or diarrhea, but these are uncommon. In pregnancy, the safety data rates it as possibly safe, though you should check with your doctor before starting.

We don't have pregnancy or lactation data on file for this specific strain, so talk with your healthcare provider about whether it's right for you if you're pregnant or breastfeeding.

Side effects, ingredient by ingredient Lactobacillus Acidophilus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lactobacillus Acidophilus.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antibiotic drugs, separate them from this probiotic by a few hours — the antibiotics will kill the live L. acidophilus organisms if taken together. Run your specific antibiotic medications through the tool on this page, or ask your doctor or pharmacist for the timing that works best for you.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you're looking to support digestive health and don't have a compromised immune system, this probiotic is worth considering — especially if you're dealing with IBS, antibiotic-associated diarrhea, or bacterial vaginosis. The main thing to watch: don't take it at the same time as antibiotics, because the antibiotics will kill the beneficial bacteria.

Check your medications with your doctor or pharmacist before you start, especially if you're on antibiotics, have a weakened immune system, or are pregnant or nursing.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Digestive Health Probiotic, straight from the product label.

Brand Meijer
Barcode (UPC) 713733919128
Net contents 30 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Sep 25, 2023
DSLD ID 296502
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Digestive Health Probiotic by Meijer, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetarian Capsule(s)
Maximum serving Sizes:
1 Vegetarian Capsule(s)
Servings per container
30
UPC/BARCODE
713733919128
IngredientAmount% DV
Lactobacillus acidophilus LA-140 NP--

Other ingredients: Cellulose, Water, Magnesium Stearate, Silica, Calcium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

The Lactobacillus acidophilus LA-14 probiotic strain helps to nurture and support healthy intestinal flora for good digestion. The strain is stabilized using a patented polymatrix system (patent # 6,653,062) that provides shelf stability at normal room temperature. 10 billion Lactobacilli per serving

General Statements

Compare vs. Culturelle

4 Week Supply

Culturelle is a registered trademark of i-Health, Inc. This product is not manufactured or distributed by i-Health, Inc.

Questions or comments? 1-800-879-8623

Meijer Pharmacists Recommended Money Back Guarantee

Formulation

Helps support your digestive system. Supports a healthy balance of good bacteria in the intestinal tract. Gives support during occasional digestive upset.

Helps support general digestive health. Helps support the digestive system during periods of gas and bloating. Helps support the immune system. Helps support the digestive system during travel.

Contains No: Lactose, artificial colors, artificial flavors or preservatives. Gluten Free.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Adults - As a dietary supplement, take one (1) vegetarian capsule daily during a meal or as directed by a health care professional.

Once Daily Formula

Precautions

Caution: If you are pregnant or nursing a baby or if you are taking any medication or have a medical condition, consult a health care professional before using this product.

Keep out of reach of children.

Do not use if printed seal under cap is broken or missing.

Storage

Store in a cool, dry place away from direct light.

No refrigeration required.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Digestive Health Probiotic by Meijer label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Digestive Health Probiotic label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Digestive Health Probiotic by Meijer

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Vegetarian Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Lactobacillus acidophilus LA-14

Interacts with
182 drugs
0 NP per serving

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy p...

Lactobacillus acidophilus LA-14 monograph & interactions

Other (inactive) ingredients: Cellulose, Water, Magnesium Stearate, Silica, Calcium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Digestive Health Probiotic by Meijer Drug Interactions

Want to check YOUR meds against Digestive Health Probiotic?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Lactobacillus acidophilus LA-14 182

Individual Drug Interactions

The ingredients in Digestive Health Probiotic interact with 182 drugs. Click any drug to see the details.

1 of the 1 ingredient in Digestive Health Probiotic interact with drugs. Each result below shows which ingredient is responsible. Lactobacillus acidophilus LA-14

Each ingredient & the kinds of drugs it affects

For each ingredient in Digestive Health Probiotic with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lactobacillus acidophilus LA-141 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Lactobacillus acidophilus LA-14 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Digestive Health Probiotic, from the product label.

Meijer

See all Meijer products
Name
Meijer Distribution, Inc.
City
Grand Rapids
State
MI
ZipCode
49544
Phone Number
1-800-879-8623
Web Address
www.meijer.com
Pharmacist Counseling Corner

Digestive Health Probiotic by Meijer: Common Questions

Does Digestive Health Probiotic by Meijer interact with any medications?
Yes. Based on its ingredients, Digestive Health Probiotic has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Digestive Health Probiotic contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this probiotic while I'm on antibiotics?
Not at the same time. Antibiotics kill the live bacteria in this probiotic, making it less effective. Ask your doctor or pharmacist how many hours to space them apart — often a few hours is enough.
Is this safe if I'm pregnant?
The safety data rates L. acidophilus as possibly safe in pregnancy, but we don't have detailed information for this specific strain. Talk with your doctor before starting if you're pregnant — they can weigh the benefits and risks for your situation.
What is Lactobacillus acidophilus?
It's a live beneficial bacterium that naturally occurs in your gut and helps with digestion. This product contains the specific strain LA-14.
Will I have side effects from this probiotic?
Most people tolerate it well. Some folks experience mild gas, bloating, or abdominal discomfort when first taking it or when combining it with other probiotics, but these effects are uncommon.
Does this probiotic actually work for IBS?
L. acidophilus is possibly effective for irritable bowel syndrome based on available evidence — meaning there's promising research, but more evidence is still needed. Results vary from person to person.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Digestive Health Probiotic is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Digestive Health Probiotic label
Go deeper

The Full Monographs Behind Digestive Health Probiotic’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph →
Sources

Sources & How We Checked

Digestive Health Probiotic's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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