Digestive Support Strawberry Flavor Ingredients & Drug Interactions
by TerraVita
What is this page for?
First and foremost: checking Digestive Support Strawberry Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Digestive Support Strawberry Flavor is a dietary supplement by TerraVita with 3 active ingredients. Its ingredients are commonly taken for urinary tract infections, urinary discomfort, mild diuretic.Based on those ingredients, 1,342 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Barberry Glycerite Liquid Extract, Uva Ursi Glycerite Liquid Extract, Peppermint Leaf Glycerite Liquid Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Digestive Support Strawberry Flavor by TerraVita
Ask about any prescription or over-the-counter medication and we check it for interactions with Digestive Support Strawberry Flavor by TerraVita — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Digestive Support Strawberry Flavor by TerraVita
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This liquid contains three active ingredients. Uva ursi (also called bearberry) and peppermint are both delivered as glycerite liquid extracts — a liquid form that preserves their plant compounds in glycerin.
The product also contains barberry glycerite, which we cannot check for interactions. The inactive ingredients are glycerin (the liquid base) and strawberry flavor.
Does it work?
Strong evidence
Peppermint shows the strongest evidence here. It's likely effective for irritable bowel syndrome (IBS) and possibly effective for indigestion, nausea from chemotherapy, and reducing cramping during medical procedures.
Uva ursi, by contrast, is possibly ineffective for urinary tract infections — one of the conditions it's traditionally used for — and we don't have reliable evidence that it works for bronchitis or benign prostate enlargement. Since we cannot check barberry's effectiveness, that data isn't on file.
How safe is it?
Well-documented data
Uva ursi is generally well tolerated at low doses for short-term use, but it carries a caution: prolonged or high-dose use can be toxic. The most common side effects are nausea, vomiting, diarrhea, and stomach upset.
At very high doses (20 grams or more of dried herb), rare but serious effects like tremors, confusion, and shortness of breath have been reported. Pregnancy is a clear concern — the safety data advises against it because uva ursi may stimulate the uterus, and there's insufficient data to know it's safe while breastfeeding.
Peppermint leaf is generally well tolerated and likely safe in pregnancy and lactation. Most people experience no side effects, though some report mild stomach discomfort, dry mouth, or heartburn.
Rare allergic reactions (including anaphylaxis) have been reported, particularly in people with a history of asthma. Concentrated peppermint oil, rather than leaf, carries higher risk and should be used only under medical supervision.
Meds to double-check
Moderate interaction found
Before taking this product, check whether you take any drugs metabolized by the liver enzymes CYP2C19, CYP2C9, or CYP3A4 — these include many heart, blood pressure, and psychiatric medications, and their levels may rise. Also double-check if you take lithium (a mood stabilizer), cyclosporine (an immunosuppressant), or urinary acidifying agents before starting.
Use the medication checker on this page to verify your specific drugs.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
This product may help with IBS and indigestion thanks to its peppermint content, but the uva ursi component shows weak evidence for its traditional uses. Because of the moderate-severity interactions with liver enzymes and lithium, check your exact medications with our tool before starting.
If you're pregnant, breastfeeding, or taking lithium or immunosuppressants, talk with your pharmacist first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Digestive Support Strawberry Flavor, straight from the product label.
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Digestive Support Strawberry Flavor by TerraVita, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 0.13 mL | -- |
| Uva Ursi Glycerite Liquid Extract | 0 NP | -- |
| Peppermint Leaf Glycerite Liquid Extract | 0 NP | -- |
| Barberry Glycerite Liquid Extract | 0 NP | -- |
Other ingredients: Glycerin, Strawberry flavor
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
Copyright 2018 TerraVita Distributed by ZooScape LLC, All Rights Reserved.
Formula
Glycerite liquid extract (1:5)
Formulation
Alcohol free
Suggested/Recommended/Usage/Directions
Suggested Use: Take 25-40 drops of extract in a small amount of warm water 3-4 times daily. Shake well before using.
Precautions
Keep away from children.
Do not use if safety seal around cap is broken or missing.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Digestive Support Strawberry Flavor by TerraVita label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Digestive Support Strawberry Flavor by TerraVita
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size25 Drop(s) Dosage formLiquid Servings per container227 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Other (inactive) ingredients: Glycerin, Strawberry flavor. These complete the product’s ingredient list but are not active constituents.
Digestive Support Strawberry Flavor by TerraVita Drug Interactions
HelloPharmacist Interaction Report
TerraVita's Digestive Support Strawberry Flavor contains two ingredients we can check for drug interactions: uva ursi and peppermint.
Together, they interact with a substantial number of medications across several categories, with the most serious concerns being moderate-severity interactions with drugs that rely on liver enzymes to break down. Altogether, these interactions span 875 individual medications.
Read the full breakdown — every affected drug type, severity by severity
Uva ursi may slow how your liver processes drugs that depend on the CYP2C19 and CYP3A4 enzyme systems, and it may raise levels of drugs cleared through a process called glucuronidation — all moderate-severity concerns based on lab studies, though no human cases have been reported. It also poses a moderate risk with lithium (a psychiatric medication), since uva ursi's diuretic properties might increase lithium levels and require a dose adjustment.
Separately, urinary acidifying agents (certain antibiotics and some other drugs) may reduce uva ursi's effects in the urinary tract.
Peppermint contributes additional moderate-severity interactions: it may increase levels of drugs metabolized by CYP2C19, CYP2C9, and CYP3A4 enzymes, and it may raise cyclosporine (an immunosuppressant) levels. It carries a minor interaction with CYP1A2 substrates, though clinical studies suggest this one is less likely to matter in practice.
We could not check barberry, as we hold no data for it. Use the medication checker below with your exact drugs before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Digestive Support Strawberry Flavor?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Digestive Support Strawberry Flavor interact with 1,342 drugs. Click any drug to see the details.
3 of the 3 ingredients in Digestive Support Strawberry Flavor interact with drugs. Each result below shows which ingredient is responsible. Barberry Glycerite Liquid Extract Uva Ursi Glycerite Liquid Extract Peppermint Leaf Glycerite Liquid Extract
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Digestive Support Strawberry Flavor — through 3 ingredients. Tap an ingredient for the detail:
Uva Ursi Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Glycerite Liquid Extract + Ado-trastuzumab Emtansine interactionBarberry Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Glycerite Liquid Extract + Ado-trastuzumab Emtansine interactionPeppermint Leaf Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP3A4 substrates.
Read the full Peppermint Leaf Glycerite Liquid Extract + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Digestive Support Strawberry Flavor — through 1 ingredient. Tap an ingredient for the detail:
Barberry Glycerite Liquid ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, European barberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Barberry Glycerite Liquid Extract + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Digestive Support Strawberry Flavor — through 3 ingredients. Tap an ingredient for the detail:
Peppermint Leaf Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP3A4 substrates.
Read the full Peppermint Leaf Glycerite Liquid Extract + Abemaciclib interactionBarberry Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Glycerite Liquid Extract + Abemaciclib interactionUva Ursi Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Glycerite Liquid Extract + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Digestive Support Strawberry Flavor — through 3 ingredients. Tap an ingredient for the detail:
Uva Ursi Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Glycerite Liquid Extract + Abiraterone interactionBarberry Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Glycerite Liquid Extract + Abiraterone interactionPeppermint Leaf Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP3A4 substrates.
Read the full Peppermint Leaf Glycerite Liquid Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Digestive Support Strawberry Flavor — through 3 ingredients. Tap an ingredient for the detail:
Peppermint Leaf Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP3A4 substrates.
Read the full Peppermint Leaf Glycerite Liquid Extract + Abiraterone Acetate interactionBarberry Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Glycerite Liquid Extract + Abiraterone Acetate interactionUva Ursi Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Glycerite Liquid Extract + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Digestive Support Strawberry Flavor — through 3 ingredients. Tap an ingredient for the detail:
Uva Ursi Glycerite Liquid ExtractCytochrome P450 2c19 (cyp2c19) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP2C19 substrates.
Read the full Uva Ursi Glycerite Liquid Extract + Abrocitinib interactionPeppermint Leaf Glycerite Liquid ExtractCytochrome P450 2c19 (cyp2c19) Substrates, Cytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP2C19 substrates.
Read the full Peppermint Leaf Glycerite Liquid Extract + Abrocitinib interactionBarberry Glycerite Liquid ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, European barberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Barberry Glycerite Liquid Extract + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Digestive Support Strawberry Flavor — through 3 ingredients. Tap an ingredient for the detail:
Barberry Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Glycerite Liquid Extract + Acalabrutinib interactionPeppermint Leaf Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP3A4 substrates.
Read the full Peppermint Leaf Glycerite Liquid Extract + Acalabrutinib interactionUva Ursi Glycerite Liquid ExtractP-glycoprotein Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may alter the levels of drugs transported by P-glycoprotein.
Read the full Uva Ursi Glycerite Liquid Extract + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Digestive Support Strawberry Flavor — through 1 ingredient. Tap an ingredient for the detail:
Barberry Glycerite Liquid ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking European barberry with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Barberry Glycerite Liquid Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Digestive Support Strawberry Flavor — through 1 ingredient. Tap an ingredient for the detail:
Barberry Glycerite Liquid ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking European barberry with antihypertensive drugs might increase the risk of hypotension.
Read the full Barberry Glycerite Liquid Extract + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Digestive Support Strawberry Flavor — through 1 ingredient. Tap an ingredient for the detail:
Barberry Glycerite Liquid ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, European barberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Barberry Glycerite Liquid Extract + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Digestive Support Strawberry Flavor — through 1 ingredient. Tap an ingredient for the detail:
Barberry Glycerite Liquid ExtractAnticholinergic Drugs, Cns Depressants Moderate
Interaction Summary
Theoretically, taking European barberry with anticholinergic drugs might cause additive effects.
Read the full Barberry Glycerite Liquid Extract + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Digestive Support Strawberry Flavor — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Glycerite Liquid ExtractGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Glycerite Liquid Extract + Acetaminophen interactionPeppermint Leaf Glycerite Liquid ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, peppermint might increase the levels of CYP1A2 substrates.
Read the full Peppermint Leaf Glycerite Liquid Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Digestive Support Strawberry Flavor — through 3 ingredients. Tap an ingredient for the detail:
Barberry Glycerite Liquid ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, European barberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Barberry Glycerite Liquid Extract + Acetaminophen, Aspirin interactionUva Ursi Glycerite Liquid ExtractGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Glycerite Liquid Extract + Acetaminophen, Aspirin interactionPeppermint Leaf Glycerite Liquid ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, peppermint might increase the levels of CYP1A2 substrates.
Read the full Peppermint Leaf Glycerite Liquid Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Digestive Support Strawberry Flavor — through 3 ingredients. Tap an ingredient for the detail:
Uva Ursi Glycerite Liquid ExtractGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Glycerite Liquid Extract + Acetaminophen, Aspirin, Caffeine interactionBarberry Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Glycerite Liquid Extract + Acetaminophen, Aspirin, Caffeine interactionPeppermint Leaf Glycerite Liquid ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP1A2 substrates.
Read the full Peppermint Leaf Glycerite Liquid Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Digestive Support Strawberry Flavor — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Glycerite Liquid ExtractGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Glycerite Liquid Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionPeppermint Leaf Glycerite Liquid ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, peppermint might increase the levels of CYP1A2 substrates.
Read the full Peppermint Leaf Glycerite Liquid Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Digestive Support Strawberry Flavor — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Glycerite Liquid ExtractGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Glycerite Liquid Extract + Acetaminophen, Butalbital interactionPeppermint Leaf Glycerite Liquid ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, peppermint might increase the levels of CYP1A2 substrates.
Read the full Peppermint Leaf Glycerite Liquid Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Digestive Support Strawberry Flavor — through 3 ingredients. Tap an ingredient for the detail:
Peppermint Leaf Glycerite Liquid ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP1A2 substrates.
Read the full Peppermint Leaf Glycerite Liquid Extract + Acetaminophen, Butalbital, Caffeine interactionUva Ursi Glycerite Liquid ExtractGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Glycerite Liquid Extract + Acetaminophen, Butalbital, Caffeine interactionBarberry Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Glycerite Liquid Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Digestive Support Strawberry Flavor — through 3 ingredients. Tap an ingredient for the detail:
Uva Ursi Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Glucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Glycerite Liquid Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionBarberry Glycerite Liquid ExtractCns Depressants, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Read the full Barberry Glycerite Liquid Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionPeppermint Leaf Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP3A4 substrates.
Read the full Peppermint Leaf Glycerite Liquid Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Digestive Support Strawberry Flavor — through 3 ingredients. Tap an ingredient for the detail:
Uva Ursi Glycerite Liquid ExtractGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Glycerite Liquid Extract + Acetaminophen, Butalbital, Codeine interactionBarberry Glycerite Liquid ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Read the full Barberry Glycerite Liquid Extract + Acetaminophen, Butalbital, Codeine interactionPeppermint Leaf Glycerite Liquid ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, peppermint might increase the levels of CYP1A2 substrates.
Read the full Peppermint Leaf Glycerite Liquid Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Digestive Support Strawberry Flavor — through 3 ingredients. Tap an ingredient for the detail:
Uva Ursi Glycerite Liquid ExtractGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Glycerite Liquid Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionBarberry Glycerite Liquid ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Read the full Barberry Glycerite Liquid Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionPeppermint Leaf Glycerite Liquid ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, peppermint might increase the levels of CYP1A2 substrates.
Read the full Peppermint Leaf Glycerite Liquid Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Digestive Support Strawberry Flavor — through 3 ingredients. Tap an ingredient for the detail:
Peppermint Leaf Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP3A4 substrates.
Read the full Peppermint Leaf Glycerite Liquid Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionBarberry Glycerite Liquid ExtractAnticholinergic Drugs, Cns Depressants +1 Moderate
Interaction Summary
Theoretically, taking European barberry with anticholinergic drugs might cause additive effects.
Read the full Barberry Glycerite Liquid Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionUva Ursi Glycerite Liquid ExtractGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Glycerite Liquid Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Digestive Support Strawberry Flavor — through 3 ingredients. Tap an ingredient for the detail:
Barberry Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Glycerite Liquid Extract + Acetaminophen, Caffeine, Codeine interactionUva Ursi Glycerite Liquid ExtractGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Glycerite Liquid Extract + Acetaminophen, Caffeine, Codeine interactionPeppermint Leaf Glycerite Liquid ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP1A2 substrates.
Read the full Peppermint Leaf Glycerite Liquid Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Digestive Support Strawberry Flavor — through 3 ingredients. Tap an ingredient for the detail:
Peppermint Leaf Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP3A4 substrates.
Read the full Peppermint Leaf Glycerite Liquid Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionBarberry Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Glycerite Liquid Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionUva Ursi Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Glucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Glycerite Liquid Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Digestive Support Strawberry Flavor — through 3 ingredients. Tap an ingredient for the detail:
Uva Ursi Glycerite Liquid ExtractGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Glycerite Liquid Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionBarberry Glycerite Liquid ExtractCns Depressants, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Read the full Barberry Glycerite Liquid Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionPeppermint Leaf Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP3A4 substrates.
Read the full Peppermint Leaf Glycerite Liquid Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Digestive Support Strawberry Flavor — through 3 ingredients. Tap an ingredient for the detail:
Peppermint Leaf Glycerite Liquid ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP1A2 substrates.
Read the full Peppermint Leaf Glycerite Liquid Extract + Acetaminophen, Caffeine, Isometheptene interactionUva Ursi Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Glucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Glycerite Liquid Extract + Acetaminophen, Caffeine, Isometheptene interactionBarberry Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Glycerite Liquid Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Digestive Support Strawberry Flavor — through 3 ingredients. Tap an ingredient for the detail:
Barberry Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Anticholinergic Drugs Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Glycerite Liquid Extract + Acetaminophen, Caffeine, Pyrilamine interactionUva Ursi Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Glucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Glycerite Liquid Extract + Acetaminophen, Caffeine, Pyrilamine interactionPeppermint Leaf Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP3A4 substrates.
Read the full Peppermint Leaf Glycerite Liquid Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Digestive Support Strawberry Flavor — through 3 ingredients. Tap an ingredient for the detail:
Barberry Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Anticholinergic Drugs Moderate
Interaction Summary
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
Read the full Barberry Glycerite Liquid Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionPeppermint Leaf Glycerite Liquid ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP1A2 substrates.
Read the full Peppermint Leaf Glycerite Liquid Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionUva Ursi Glycerite Liquid ExtractGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Glycerite Liquid Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Digestive Support Strawberry Flavor — through 3 ingredients. Tap an ingredient for the detail:
Uva Ursi Glycerite Liquid ExtractGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Glycerite Liquid Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionBarberry Glycerite Liquid ExtractCns Depressants, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Read the full Barberry Glycerite Liquid Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionPeppermint Leaf Glycerite Liquid ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP1A2 substrates.
Read the full Peppermint Leaf Glycerite Liquid Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Digestive Support Strawberry Flavor — through 3 ingredients. Tap an ingredient for the detail:
Barberry Glycerite Liquid ExtractAnticholinergic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking European barberry with anticholinergic drugs might cause additive effects.
Read the full Barberry Glycerite Liquid Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionPeppermint Leaf Glycerite Liquid ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP1A2 substrates.
Read the full Peppermint Leaf Glycerite Liquid Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionUva Ursi Glycerite Liquid ExtractGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Glycerite Liquid Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Digestive Support Strawberry Flavor — through 3 ingredients. Tap an ingredient for the detail:
Uva Ursi Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Glucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Glycerite Liquid Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionPeppermint Leaf Glycerite Liquid ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, peppermint might increase the levels of CYP3A4 substrates.
Read the full Peppermint Leaf Glycerite Liquid Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionBarberry Glycerite Liquid ExtractAnticholinergic Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking European barberry with anticholinergic drugs might cause additive effects.
Read the full Barberry Glycerite Liquid Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Digestive Support Strawberry Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Barberry Glycerite Liquid Extract
Anticholinergic Drugs
Theoretically, taking European barberry with anticholinergic drugs might cause additive effects.
In vitro evidence suggests that European barberry might have anticholinergic properties.
Anticoagulant/Antiplatelet Drugs
Theoretically, European barberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal evidence suggest that berberine, a constituent of European barberry, might inhibit platelet aggregation. Theoretically, European barberry might have a similar effect.
Antidiabetes Drugs
Theoretically, taking European barberry with antidiabetes drugs might increase the risk of hypoglycemia.
Preliminary clinical evidence suggests that European barberry juice reduces fasting glucose levels in patients with type 2 diabetes who are also taking antidiabetes drugs. Additionally, some animal studies show that berberine, a constituent of European barberry, has antiglycemic potential. Monitor blood glucose levels closely.
Antihypertensive Drugs
Theoretically, taking European barberry with antihypertensive drugs might increase the risk of hypotension.
Animal and human research suggests that European barberry extracts can have hypotensive effects.
Cholinergic Drugs
Theoretically, taking European barberry with cholinergic drugs might decrease the effects of cholinergic drugs.
In vitro evidence suggests that European barberry might have anticholinergic properties.
Cns Depressants
Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Animal research suggests that berberine, a constituent of European barberry, might have sedative effects. Theoretically, European barberry might have a similar effect.
Cyclosporine (Neoral, Sandimmune)
Theoretically, concomitant use with cyclosporine may cause additive effects.
Berberine, a constituent of European barberry, can reduce the metabolism and increase serum levels of cyclosporine. This effect is attributed to the ability of berberine to inhibit cytochrome P450 3A4 (CYP3A4), which metabolizes cyclosporine. Theoretically, European barberry might have a similar effect.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
There is very preliminary evidence suggesting that berberine, a constituent of European barberry, might inhibit the CYP3A4 enzyme. Theoretically, European barberry might have a similar effect.
Uva Ursi Glycerite Liquid Extract
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, uva ursi may decrease the metabolism of CYP2C19 substrates.
In vitro, uva ursi appears to inhibit cytochrome CYP2C19. This effect has not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
In vitro, uva ursi appears to inhibit CYP3A4. This effect has not been reported in humans.
Glucuronidated Drugs
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
In vitro, uva ursi extract appears to strongly inhibit UDP-glucuronosyltransferase (UGT) 1A1 (UGT1A1). However, uva ursi extract does not appear to inhibit UGT1A1 in animal models. This effect has not been reported in humans.
Lithium
Theoretically, uva ursi may increase lithium levels, necessitating a decrease in dose.
Uva ursi may have diuretic properties. Diuretics may increase lithium reabsorption with sodium in the proximal tubule of the kidney. Theoretically, uva ursi might reduce excretion and increase levels of lithium.
Urinary Acidifying Agents
Effects of uva ursi in the urinary tract may be reduced by urinary acidifying agents.
Uva ursi seems to work best in alkaline urine. Theoretically, taking uva ursi with medications known to acidify the urine may decrease any effects of uva ursi on the urinary tract.
P-Glycoprotein Substrates
Theoretically, uva ursi may alter the levels of drugs transported by P-glycoprotein.
In vitro, uva ursi appears to inhibit the multi-drug transporter protein, P-glycoprotein. This effect has not been reported in humans.
Peppermint Leaf Glycerite Liquid Extract
Cyclosporine (Neoral, Sandimmune)
Theoretically, peppermint oil might increase the levels and adverse effects of cyclosporine.
In animal research, peppermint oil inhibits cyclosporine metabolism and increases cyclosporine levels. Inhibition of cytochrome P450 3A4 (CYP3A4) may be partially responsible for this interaction. An interaction between peppermint oil and cyclosporine has not been reported in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, peppermint might increase the levels of CYP2C19 substrates.
In vitro research shows that peppermint oil inhibits CYP2C19. So far, this interaction has not been reported in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, peppermint might increase the levels of CYP2C9 substrates.
In vitro research shows that peppermint oil inhibits CYP2C9. So far, this interaction has not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, peppermint might increase the levels of CYP3A4 substrates.
Clinical research in healthy volunteers shows that a single dose of peppermint oil 600 mg inhibits CYP3A4 enzymes and increases the AUC of felodipine, a CYP3A4 substrate. However, in vitro research suggests that peppermint oil only inhibits CYP3A4 at very high concentrations.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, peppermint might increase the levels of CYP1A2 substrates.
In vitro and animal research shows that peppermint oil and peppermint leaf inhibit CYP1A2. However, in clinical research, peppermint tea did not significantly affect the metabolism of caffeine, a CYP1A2 substrate. It is possible that the 6-day duration of treatment may have been too short to identify a difference.
Brand information
Manufacturer and brand details for Digestive Support Strawberry Flavor, from the product label.
TerraVita
See all TerraVita products- Name
- ZooScape LLC
- Phone Number
- 844-449-0444
- Web Address
- www.ZooScape.com
Digestive Support Strawberry Flavor by TerraVita: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Digestive Support Strawberry Flavor’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Uva Ursi
Interacts with 803 drugsUva ursi is a traditional herb used mainly for urinary tract infections, and its leaves contain a compound called arbutin that may have antimicrobial effects in the urine. Evidence in people...
Read the full Uva Ursi monograph → Herb & supplement monographPeppermint
Interacts with 796 drugsPeppermint is a popular herb with the best evidence supporting enteric-coated peppermint oil for easing IBS symptoms. It is generally well tolerated for most adults, but it can cause heartbu...
Read the full Peppermint monograph → Herb & supplement monographEuropean Barberry
Interacts with 1,210 drugsEuropean barberry is a shrub whose root, bark, and berries contain berberine, a bitter plant alkaloid that has been studied mostly in isolated form. Some early research on berberine is promi...
Read the full European Barberry monograph →Sources & How We Checked
Digestive Support Strawberry Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 64 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Uva Ursi 8 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. Terry C. Telger, transl. 3rd ed. Berlin, GER: Springer, 1998.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Wang L, Del Priore LV. Bull's-eye maculopathy secondary to herbal toxicity from uva ursi. Am J Ophthalmol 2004;137:1135-7. PubMed
- Beaux, D., Fleurentin, J., and Mortier, F. Effect of extracts of Orthosiphon stamineus Benth, Hieracium pilosella L., Sambucus nigra L. and Arctostaphylos uva-ursi (L.) Spreng. in rats. Phytother.Res 1999;13(3):222-225.
- de Arriba SG, Naser B, Nolte KU. Risk assessment of free hydroquinone derived from Arctostaphylos Uva-ursi folium herbal preparations. Int J Toxicol. 2013;32(6):442-453.
- Park JB, Kim D, Min JS, et al. Identification and characterization of in vitro inhibitors against UDP-glucuronosyltransferase 1A1 in uva-ursi extracts and evaluation of in vivo uva-ursi-drug interactions. Food Chem Toxicol. 2018;120:651-661. PubMed
- Chauhan B, Yu C, Krantis A, et al. In vitro activity of uva-ursi against cytochrome P450 isoenzymes and P-glycoprotein. Can J Physiol Pharmacol. 2007;85(11):1099-107.
Peppermint 41 references
- Liu JH, Chen GH, Yeh HZ, et al. Enteric-coated peppermint-oil capsules in the treatment of irritable bowel syndrome: a prospective, randomized trial. J Gastroenterol 1997;32:765-8. PubMed
- Pittler MH, Ernst E. Peppermint oil for irritable bowel syndrome: a critical review and metaanalysis. Am J Gastroenterol 1998;93:1131-5. PubMed
- Kline RM, Kline JJ, Di Palma J, Barbero GJ. Enteric-coated, pH-dependent peppermint oil capsules for the treatment of irritable bowel syndrome in children. J Pediatr 2001;138:125-8. PubMed
- Madisch A, Heydenreich CJ, Wieland V, et al. Treatment of functional dyspepsia with a fixed peppermint oil and caraway oil combination preparation as compared to cisapride. A multicenter, reference-controlled, double-blind equivalence study. Arzneimittel
- May B, Kuntz HD, Kieser M, Kohler S. Efficacy of a fixed peppermint oil/caraway oil combination in non-ulcer dyspepsia. Arzneimittelforschung 1996;46:1149-53.
- Micklefield GH, Greving I, May B. Effects of peppermint oil and caraway oil on gastroduodenal motility. Phytother Res 2000;14:20-3. DOI
- Morton CA, Garioch J, Todd P, et al. Contact sensitivity to menthol and peppermint in patients with intra-oral symptoms. Contact Dermatitis 1995;32:281-4. PubMed
- May B, Kohler S, Schneider B. Efficacy and tolerability of a fixed combination of peppermint oil and caraway oil in patients suffering from functional dyspepsia. Aliment Pharmacol Ther 2000;14:1671-7. PubMed
- Nash P, Gould SR, Bernardo DE. Peppermint oil does not relieve the pain of irritable bowel syndrome. Br J Clin Pract 1986;40:292-3. DOI
- Rees WD, Evans BK, Rhodes J. Treating irritable bowel syndrome with peppermint oil. Br Med J 1979;2:835-6. PubMed
- Davies SJ, Harding LM, Baranowski AP. A novel treatment of postherpetic neuralgia using peppermint oil. Clin J Pain 2002;18:200-2. PubMed
- Weston CF. Anal burning and peppermint oil. Postgrad Med J 1987;63:717. PubMed
- Dresser GK, Wacher V, Wong S, et al. Evaluation of peppermint oil and ascorbyl palmitate as inhibitors of cytochrome P4503A4 activity in vitro and in vivo. Clin Pharmacol Ther 2002;72:247-55. PubMed
- Wacher VJ, Wong S, Wong HT. Peppermint oil enhances cyclosporine oral bioavailability in rats: comparison with D-alpha-tocopheryl poly(ethylene glycol 1000) succinate (TPGS) and ketoconazole. J Pharm Sci 2002;91:77-90.
- Lawson MJ, Knight RE, Tran K, et al. Failure of enteric-coated peppermint oil in the irritable bowel syndrome: a randomized double-blind crossover study. J Gastroenterol Hepatol 1988;3:235-8. DOI
- Unger M, Frank A. Simultaneous determination of the inhibitory potency of herbal extracts on the activity of six major cytochrome P450 enzymes using liquid chromatography/mass spectrometry and automated online extraction. Rapid Commun Mass Spectrom 2004;1 PubMed
- Maliakal PP, Wanwimolruk S. Effect of herbal teas on hepatic drug metabolizing enzymes in rats. J Pharm Pharmacol 2001;53:1323-9. PubMed
- Rogers SN, Pahor AL. A form of stomatitis induced by excessive peppermint consumption. Dent Update 1995;22:36-7.
- Cappello G, Spezzaferro M, Grossi L, et al. Peppermint oil (Mintoil) in the treatment of irritable bowel syndrome: a prospective double blind placebo-controlled randomized trial. Dig Liver Dis 2007;39:530-6. PubMed
- Moghadam BK, Gier R, and Thurlow T. Extensive oral mucosal ulcerations caused by misuse of a commercial mouthwash. Cutis 1999;64:131-134.
- Andersen, K. E. Contact allergy to toothpaste flavors. Contact Dermatitis 1978;4(4):195-198. PubMed
- Barnard, D. R. Repellency of essential oils to mosquitoes (Diptera: Culicidae). J Med Entomol. 1999;36(5):625-629. PubMed
- Tamir, S., Davidovich, Z., Attal, P., and Eliashar, R. Peppermint oil chemical burn. Otolaryngol.Head Neck Surg. 2005;133(5):801-802. PubMed
- Kalavala, M., Hughes, T. M., Goodwin, R. G., Anstey, A. V., and Stone, N. M. Allergic contact dermatitis to peppermint foot spray. Contact Dermatitis 2007;57(1):57-58. PubMed
- Vermaat, H., van Meurs, T., Rustemeyer, T., Bruynzeel, D. P., and Kirtschig, G. Vulval allergic contact dermatitis due to peppermint oil in herbal tea. Contact Dermatitis 2008;58(6):364-365. PubMed
- Merat, S., Khalili, S., Mostajabi, P., Ghorbani, A., Ansari, R., and Malekzadeh, R. The effect of enteric-coated, delayed-release peppermint oil on irritable bowel syndrome. Dig.Dis.Sci. 2010;55(5):1385-1390. PubMed
- Tran, A., Pratt, M., and DeKoven, J. Acute allergic contact dermatitis of the lips from peppermint oil in a lip balm. Dermatitis 2010;21(2):111-115. DOI
- Hitz, Lindenmuller, I and Lambrecht, J. T. Oral care. Curr Probl.Dermatol 2011;40:107-115.
- Shavakhi, A., Ardestani, S. K., Taki, M., Goli, M., and Keshteli, A. H. Premedication with peppermint oil capsules in colonoscopy: a double blind placebo-controlled randomized trial study. Acta Gastroenterol Belg 2012;75(3):349-353.
- Lech, Y., Olesen, K. M., Hey, H., Rask-Pedersen, E., Vilien, M., and Ostergaard, O. [Treatment of irritable bowel syndrome with peppermint oil. A double- blind study with a placebo]. Ugeskr.Laeger 10-3-1988;150(40):2388-2389.
- Parys, B. T. Chemical burns resulting from contact with peppermint oil mar: a case report. Burns Incl.Therm.Inj. 1983;9(5):374-375. PubMed
- Bayat R, Borici-Mazi R. A case of anaphylaxis to peppermint. Allergy Asthma Clin Immunol. 2014;10(1):6. PubMed
- Rich G, Shah A, Koloski N, et al. A randomized placebo-controlled trial on the effects of Menthacarin, a proprietary peppermint- and caraway-oil-preparation, on symptoms and quality of life in patients with functional dyspepsia. Neurogastroenterol Motil 2 PubMed
- Douros A, Bronder E, Andersohn F, et al. Herb-Induced Liver Injury in the Berlin Case-Control Surveillance Study. Int J Mol Sci 2016;17(1). PubMed
- Begas E, Tsioutsiouliti A, Kouvaras E, et al. Effects of peppermint tea consumption on the activities of CYP1A2, CYP2A6, Xanthine Oxidase, N-acetyltranferase-2 and UDP-glucuronosyltransferases-1A1/1A6 in healthy volunteers. Food Chem Toxicol 2017;100:80-9 PubMed
- Cash BD, Epstein MS, Shah SM. A Novel Delivery System of Peppermint Oil Is an Effective Therapy for Irritable Bowel Syndrome Symptoms. Dig Dis Sci 2016;61(2):560-71. PubMed
- Elsaie LT, El Mohsen AM, Ibrahim IM, Mohey-Eddin MH, Elsaie ML. Effectiveness of topical peppermint oil on symptomatic treatment of chronic pruritus. Clin Cosmet Investig Dermatol 2016;9:333-8. PubMed
- Wu J, Xu R, Zhan R, et al. Effective symptomatic treatment for severe and intractable pruritus associated with severe burn-induced hypertrophic scars: A prospective, multicenter, controlled trial. Burns 2016;42(5):1059-66. PubMed
- Weerts ZZRM, Masclee AAM, Witteman BJM, et al. Efficacy and safety of peppermint oil in a randomized, double-blind trial of patients with irritable bowel syndrome. Gastroenterology. 2020;158(1):123-136. PubMed
- Nee J, Ballou S, Kelley JM, et al. Peppermint Oil Treatment for Irritable Bowel Syndrome: A Randomized Placebo-Controlled Trial. Am J Gastroenterol 2021;116(11):2279-2285. PubMed
- Ingrosso MR, Ianiro G, Nee J, et al. Systematic review and meta-analysis: efficacy of peppermint oil in irritable bowel syndrome. Aliment Pharmacol Ther 2022;56(6):932-41. PubMed
European Barberry 15 references
- Chan E. Displacement of bilirubin from albumin by berberine. Biol Neonate 1993;63:201-8. PubMed
- Wu X, Li Q, Xin H, Yu A, Zhong M. Effects of berberine on the blood concentration of cyclosporin A in renal transplanted recipients: clinical and pharmacokinetic study. Eur J Clin Pharmacol 2005;61:567-72. PubMed
- Shamsa F, Ahmadiani A, Khosrokhavar R. Antihistaminic and anticholinergic activity of barberry fruit (Berberis vulgaris) in the guinea-pig ileum. J Ethnopharmacol 1999;64:161-6. PubMed
- Fatehi M, Saleh TM, Fatehi-Hassanabad Z, et al. A pharmacological study on Berberis vulgaris fruit extract. J Ethnopharmacol 2005;102:46-52. PubMed
- Kostalova, D., Bukovsky, M., Koscova, H., and Kardosova, A. [Anticomplement activity of Mahonia aquifolium bisbenzylisoquinoline alkaloids and berberine extract]. Ceska.Slov.Farm 2001;50(6):286-289.
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