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Dietary supplement

DMAE Bitartrate 250 mg Ingredients & Drug Interactions

by Intensive Nutrition

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

DMAE Bitartrate 250 mg is a dietary supplement by Intensive Nutrition with 1 active ingredient. Its ingredients are commonly taken for memory and focus, mood and mental clarity, adhd-type symptoms.Based on those ingredients, 219 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are DMAE-bitartrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of DMAE Bitartrate 250 mg by Intensive Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: DMAE-bitartrate (dimethylaminoethanol bitartrate), which is thought to raise levels of acetylcholine, a chemical messenger in the brain. The capsule also contains microcrystalline cellulose and magnesium stearate as inactive ingredients (binders and flow agents).

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Deanol product and its label doesn't state a use — see Deanol's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for DMAE-bitartrate is limited. It is rated likely ineffective for Alzheimer disease and tardive dyskinesia (involuntary movement disorder).

For aging skin, athletic performance, and ADHD, there is insufficient reliable evidence to rate whether it works.

The evidence, ingredient by ingredient Deanol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Deanol is generally well tolerated orally, but side effects can occur and the evidence base is limited. The most common adverse effects reported are abdominal cramps, abdominal pain, diarrhea, drowsiness, nausea, and vomiting.

Other reported effects include headache, insomnia, overstimulation, lucid dreams, confusion, depression, and hypomania. At doses above 1,000 mg daily, mood changes (depression and hypomania) have been reported, especially in people with psychiatric conditions; doses of 1,500 mg daily have been linked to worsening schizophrenic symptoms in patients with chronic schizophrenia.

Pregnancy safety data is not on file. Because safety during breastfeeding is unknown, the data advises against use while breastfeeding.

Side effects, ingredient by ingredient Deanol

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Deanol.
  • The most serious interaction on file is rated Minor.
  • For scale: 219 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your pharmacist or doctor if you take anticholinergic drugs (common for urinary incontinence, eye problems, or movement disorders) or cholinergic drugs (used for myasthenia gravis, Alzheimer disease, or glaucoma), since deanol may decrease the effect of one group and increase the effect of the other.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

DMAE-bitartrate may be worth considering if you're curious about brain health and are not taking anticholinergic or cholinergic medications, but the evidence for its effectiveness is limited and side effects do occur. If you take any psychiatric medications, drugs for urinary or eye issues, or movement-disorder treatments, talk with your doctor or pharmacist before starting.

The same goes if you're pregnant or breastfeeding—your healthcare provider can help you weigh the risks and benefits for your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about DMAE Bitartrate 250 mg, straight from the product label.

Brand Intensive Nutrition
Net contents 100 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Sep 25, 2013
DSLD ID 23663
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for DMAE Bitartrate 250 mg by Intensive Nutrition , sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
IngredientAmount% DV
DMAE-bitartrate250 mg--

Other ingredients: Microcrystalline Cellulose, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: 4 capsules daily between meals or as directed by your health professional.

FDA Statement of Identity

Dietary Supplement

Formula

DMAE-bitartrate is a nutrient belonging to the Vitamin B complex group. It is complexed from pharmaceutical grade Dimethylaminoethanol and Tartanic acid.

Precautions

Caution: Keep the bottle closed in a cool, dry place and out of the reach of children.

Storage

Caution: Keep the bottle closed in a cool, dry place and out of the reach of children.

General Statements

Made in U.S.A.

Formulation

FREE OF YEAST, EGG, MILK, STARCH, CORN, SUGAR, ARTIFICIAL COLORS, SWEETENERS OR PRESERVATIVES.

General

#117

See for yourself

DMAE Bitartrate 250 mg by Intensive Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in DMAE Bitartrate 250 mg by Intensive Nutrition

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

DMAE-bitartrate

Interacts with
219 drugs
250 mg per serving

Deanol (DMAE) is a compound related to choline that is marketed for memory, focus, and mood, but solid human evidence for most of these uses is limite...

DMAE-bitartrate monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

DMAE Bitartrate 250 mg by Intensive Nutrition Drug Interactions

Want to check YOUR meds against DMAE Bitartrate 250 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
219Drugs
219 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in DMAE Bitartrate 250 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

DMAE-bitartrate2 drug types · 219 drugs

Anticholinergic Drugs

Theoretically, deanol might decrease the effectiveness of anticholinergic drugs.
Deanol is thought to increase acetylcholine levels.

Likelihood Unlikely Evidence D
Cholinergic Drugs

Theoretically, deanol might increase the effects and adverse effects of cholinergic drugs.
Deanol is thought to increase acetylcholine levels.

Likelihood Unlikely Evidence D
The maker

Brand information

Manufacturer and brand details for DMAE Bitartrate 250 mg, from the product label.

Pharmacist Counseling Corner

DMAE Bitartrate 250 mg by Intensive Nutrition : Common Questions

Does DMAE Bitartrate 250 mg by Intensive Nutrition interact with any medications?
Yes. Based on its ingredients, DMAE Bitartrate 250 mg has a known interaction with 219 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
DMAE Bitartrate 250 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant?
Pregnancy safety data for DMAE-bitartrate is not on file. Because there isn't enough information to know whether it's safe or unsafe during pregnancy, talk with your doctor or pharmacist before using it.
Can I take this while breastfeeding?
Safety during breastfeeding is unknown, and the data advises against use while breastfeeding. Speak with your doctor or pharmacist to discuss safer alternatives or whether the benefits might outweigh the risks in your situation.
What are the most common side effects?
The most frequently reported side effects are abdominal cramps, abdominal pain, diarrhea, drowsiness, nausea, and vomiting. Other possible effects include headache, insomnia, overstimulation, and mood changes.
Does this actually work for Alzheimer disease?
No—DMAE-bitartrate is rated likely ineffective for Alzheimer disease based on the evidence we hold. It's also rated likely ineffective for tardive dyskinesia.
Can this help with focus or athletic performance?
There is insufficient reliable evidence in our data to know whether it helps with either ADHD symptoms or athletic performance. The evidence just isn't established yet.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if DMAE Bitartrate 250 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

DMAE Bitartrate 250 mg label
Go deeper

The Full Monographs Behind DMAE Bitartrate 250 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

DMAE Bitartrate 250 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Deanol 15 references
  1. Davies C, Maidment S, Hanley P, et al. Dimethylaminoethanol (DMAE). HSE. Risk assessment document; EH72/2;1997. (TOXLINE).
  2. Re O. 2-Dimethylaminoethanol (deanol): a brief review of its clinical efficacy and postulated mechanism of action. Curr Ther Res Clin Exp 1974;16:1238-42.
  3. Pieralisi G, Ripari P, Vecchiet L. Effects of a standardized ginseng extract combined with dimethylaminoethanol bitartrate, vitamins, minerals, and trace elements on physical performance during exercise. Clin Ther 1991;13:373-82.
  4. George J, Pridmore S, Aldous D. Double blind controlled trial of deanol in tardive dyskinesia. Aust N Z J Psychiatry 1981;15:68-71. PubMed
  5. Penovich P, Morgan JP, Kerzner B, et al. Double-blind evaluation of deanol in tardive dyskinesia. JAMA 1978;239:1997-8. DOI
  6. de Montigny C, Chouinard G, Annable L. Ineffectiveness of deanol in tardive dyskinesia: a placebo controlled study. Psychopharmacology (Berl) 1979;65:219-23. PubMed
  7. Lindeboom SF, Lakke JP. Deanol and physostigmine in the treatment of L-dopa-induced dyskinesias. Acta Neurol Scand 1978;58:134-8. PubMed
  8. Jus A, Villeneuve A, Gautier J, et al. Deanol, lithium and placebo in the treatment of tardive dyskinesia. A double-blind crossover study. Neuropsychobiology 1978;4:140-9. PubMed
  9. Lewis JA, Young R. Deanol and methylphenidate in minimal brain dysfunction. Clin Pharmacol Ther 1975;17:534-40. PubMed
  10. Fisman M, Mersky H, Helmes E. Double-blind trial of 2-dimethylaminoethanol in Alzheimer's disease. Am J Psychiatry 1981;138:970-2. PubMed
  11. Ferris SH, Sathananthan G, Gershon S, et al. Senile dementia: treatment with deanol. J Am Geriatr Soc 1977;25:241-4. PubMed
  12. Haug BA, Holzgraefe M. Orofacial and respiratory tardive dyskinesia: potential side effects of 2-dimethylaminoethanol (deanol)? Eur Neurol 1991;31:423-5. PubMed
  13. Casey DE. Mood alterations during deanol therapy. Psychopharmacology (Berl) 1979;62:187-91. PubMed
  14. Sergio W. Use of DMAE (2-dimethylaminoethanol) in the induction of lucid dreams. Med Hypotheses 1988;26:255-7. PubMed
  15. Osol A, Hoover JE, eds. Remington's Pharmaceutical Science, 15th ed. Easton, PA: Mack Publishing Company, 1975.

See these in context on the Deanol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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