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Dietary supplement

DMAE Bitartrate Ingredients & Drug Interactions

by BulkSupplements.com

DMAE Bitartrate label
See full label image
Powder Category: Non-nutrient/non-botanical
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking DMAE Bitartrate against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

DMAE Bitartrate is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for memory and focus, mood and mental clarity, adhd-type symptoms.Based on those ingredients, 219 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Dimethylethanolamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against DMAE Bitartrate by BulkSupplements.com

Ask about any prescription or over-the-counter medication and we check it for interactions with DMAE Bitartrate by BulkSupplements.com — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of DMAE Bitartrate by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: dimethylethanolamine, also called deanol. It's marketed as a cognitive and mood support supplement.

There are no inactive ingredients listed.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Deanol product and its label doesn't state a use — see Deanol's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for deanol is limited. It's rated likely ineffective for Alzheimer disease and tardive dyskinesia (a movement disorder).

For aging skin, ADHD, and athletic performance, there isn't enough reliable evidence to say whether it works. The research just isn't there to back up most claims made about this ingredient.

The evidence, ingredient by ingredient Deanol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Deanol is generally tolerated by some adults, but safety data are limited and side effects do occur. The most common ones are abdominal cramps and pain, diarrhea, drowsiness, nausea, and vomiting.

At doses above 1,000 mg daily, it's been reported to cause mood changes including depression and hypomania (unusually elevated mood), especially in people with existing psychiatric conditions. At 1,500 mg daily, it's been reported to worsen schizophrenia symptoms in people with that diagnosis.

Other reported effects include constipation, headache, insomnia, confusion, and in some cases an increase in lucid dreams. The safety data during pregnancy are not on file.

There isn't enough safety data to recommend this during breastfeeding.

Side effects, ingredient by ingredient Deanol

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Deanol.
  • The most serious interaction on file is rated Minor.
  • For scale: 219 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications if you take cholinergic drugs (which raise acetylcholine levels) or anticholinergic drugs (which block it) — deanol may change how these work. If you're on anything for your brain, mood, or nervous system, run it through the checker below before you start.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

DMAE Bitartrate is a single-ingredient supplement with limited evidence backing its use and a fairly long list of possible side effects. If you take anticholinergic or cholinergic medications, check with your doctor or pharmacist before starting it.

Given the weak effectiveness data and unknown pregnancy safety, it's worth discussing with your healthcare provider whether this is right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 23, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about DMAE Bitartrate, straight from the product label.

Brand BulkSupplements.com
Barcode (UPC) X000HNR4UF
Net contents 1 kg; 35.3 Oz(s)
Market status On market
Date entered into DSLD Jun 23, 2021
DSLD ID 252515
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for DMAE Bitartrate by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
350 Milligram(s)
Maximum serving Sizes:
350 Milligram(s)
Servings per container
2857
UPC/BARCODE
X000HNR4UF
IngredientAmount% DV
Dimethylethanolamine130 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Clean & Pure Bulk Supplements

Formula

(Dimethylethanolamine Bitartrate)

FDA Disclaimer Statement

Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Always consult a physician before taking any dietary supplement.

Keep out of reach of children.

Formulation

Free of: Added sugar, soy, dairy, yeast, gluten, additives

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 350 mg (about 1/8 tsp) once or twice daily, or as directed by a physician.

Storage

Store in a dry, cool place

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

DMAE Bitartrate by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

DMAE Bitartrate label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in DMAE Bitartrate by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size350 Milligram(s) Dosage formPowder Servings per container2857 Amounts shown are per serving.

Dimethylethanolamine

Interacts with
219 drugs
130 mg per serving Form: Dimethylethanolamine Bitartrate

Deanol (DMAE) is a compound related to choline that is marketed for memory, focus, and mood, but solid human evidence for most of these uses is limite...

Dimethylethanolamine monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

DMAE Bitartrate by BulkSupplements.com Drug Interactions

Want to check YOUR meds against DMAE Bitartrate?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
219Drugs
219 Minor

Ingredients driving the most interactions

Dimethylethanolamine 219

Individual Drug Interactions

The ingredients in DMAE Bitartrate interact with 219 drugs. Click any drug to see the details.

1 of the 1 ingredient in DMAE Bitartrate interact with drugs. Each result below shows which ingredient is responsible. Dimethylethanolamine

Each ingredient & the kinds of drugs it affects

For each ingredient in DMAE Bitartrate with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Dimethylethanolamine2 drug types · 219 drugs

Anticholinergic Drugs

Theoretically, deanol might decrease the effectiveness of anticholinergic drugs.
Deanol is thought to increase acetylcholine levels.

Likelihood Unlikely Evidence D
Cholinergic Drugs

Theoretically, deanol might increase the effects and adverse effects of cholinergic drugs.
Deanol is thought to increase acetylcholine levels.

Likelihood Unlikely Evidence D
Dimethylethanolamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for DMAE Bitartrate, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Rd
City
Henderson
State
NV
ZipCode
89011
Web Address
BulkSupplements.com
Pharmacist Counseling Corner

DMAE Bitartrate by BulkSupplements.com: Common Questions

Does DMAE Bitartrate by BulkSupplements.com interact with any medications?
Yes. Based on its ingredients, DMAE Bitartrate has a known interaction with 219 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
DMAE Bitartrate contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is DMAE and what's it supposed to do?
DMAE, or dimethylethanolamine, is a compound marketed for cognitive and mood support. It's thought to increase acetylcholine, a brain chemical involved in memory and focus. The evidence for its actual benefits is weak, though — it's rated likely ineffective for Alzheimer disease and tardive dyskinesia.
What are the most common side effects?
The most commonly reported side effects are abdominal cramps and pain, diarrhea, drowsiness, nausea, and vomiting. Others include constipation, headache, insomnia, and confusion. Most people tolerate it, but side effects do happen.
Is it safe to take if I have a psychiatric condition?
Caution is advised. At doses above 1,000 mg daily, deanol has been reported to cause mood changes including depression and hypomania in people with psychiatric conditions. At 1,500 mg daily, it's been reported to worsen schizophrenia symptoms. Talk with your doctor before starting it.
Can I take this while pregnant or breastfeeding?
There isn't enough safety data on file to know whether this is safe during pregnancy. The safety data aren't sufficient to recommend it during breastfeeding. Talk with your doctor or pharmacist about whether this is right for you in either situation.
How many active ingredients are in this?
Just one — dimethylethanolamine (deanol). There are no inactive ingredients listed either.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if DMAE Bitartrate is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

DMAE Bitartrate label
Go deeper

The Full Monographs Behind DMAE Bitartrate’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Deanol

Interacts with 219 drugs

Deanol (DMAE) is a compound related to choline that is marketed for memory, focus, and mood, but solid human evidence for most of these uses is limited or mixed. It can cause side effects in...

Read the full Deanol monograph →
Sources

Sources & How We Checked

DMAE Bitartrate's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Deanol 15 references
  1. Davies C, Maidment S, Hanley P, et al. Dimethylaminoethanol (DMAE). HSE. Risk assessment document; EH72/2;1997. (TOXLINE).
  2. Re O. 2-Dimethylaminoethanol (deanol): a brief review of its clinical efficacy and postulated mechanism of action. Curr Ther Res Clin Exp 1974;16:1238-42.
  3. Pieralisi G, Ripari P, Vecchiet L. Effects of a standardized ginseng extract combined with dimethylaminoethanol bitartrate, vitamins, minerals, and trace elements on physical performance during exercise. Clin Ther 1991;13:373-82.
  4. George J, Pridmore S, Aldous D. Double blind controlled trial of deanol in tardive dyskinesia. Aust N Z J Psychiatry 1981;15:68-71. PubMed
  5. Penovich P, Morgan JP, Kerzner B, et al. Double-blind evaluation of deanol in tardive dyskinesia. JAMA 1978;239:1997-8. DOI
  6. de Montigny C, Chouinard G, Annable L. Ineffectiveness of deanol in tardive dyskinesia: a placebo controlled study. Psychopharmacology (Berl) 1979;65:219-23. PubMed
  7. Lindeboom SF, Lakke JP. Deanol and physostigmine in the treatment of L-dopa-induced dyskinesias. Acta Neurol Scand 1978;58:134-8. PubMed
  8. Jus A, Villeneuve A, Gautier J, et al. Deanol, lithium and placebo in the treatment of tardive dyskinesia. A double-blind crossover study. Neuropsychobiology 1978;4:140-9. PubMed
  9. Lewis JA, Young R. Deanol and methylphenidate in minimal brain dysfunction. Clin Pharmacol Ther 1975;17:534-40. PubMed
  10. Fisman M, Mersky H, Helmes E. Double-blind trial of 2-dimethylaminoethanol in Alzheimer's disease. Am J Psychiatry 1981;138:970-2. PubMed
  11. Ferris SH, Sathananthan G, Gershon S, et al. Senile dementia: treatment with deanol. J Am Geriatr Soc 1977;25:241-4. PubMed
  12. Haug BA, Holzgraefe M. Orofacial and respiratory tardive dyskinesia: potential side effects of 2-dimethylaminoethanol (deanol)? Eur Neurol 1991;31:423-5. PubMed
  13. Casey DE. Mood alterations during deanol therapy. Psychopharmacology (Berl) 1979;62:187-91. PubMed
  14. Sergio W. Use of DMAE (2-dimethylaminoethanol) in the induction of lucid dreams. Med Hypotheses 1988;26:255-7. PubMed
  15. Osol A, Hoover JE, eds. Remington's Pharmaceutical Science, 15th ed. Easton, PA: Mack Publishing Company, 1975.

See these in context on the Deanol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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