Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Dream Herb Ingredients & Drug Interactions

by Herbal Terra

Dream Herb label
See full label image
Liquid Category: Botanical
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Dream Herb against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Dream Herb is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for promoting vivid or lucid dreams, sleep and relaxation, digestive upset.Based on those ingredients, 334 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Dream Herb Leaf, Stem Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Dream Herb by Herbal Terra

Ask about any prescription or over-the-counter medication and we check it for interactions with Dream Herb by Herbal Terra — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Dream Herb by Herbal Terra

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Dream Herb contains one active ingredient: Calea zacatechichi leaf, stem extract in dry form. It's a traditional herbal extract with a long history of folk use.

The product also contains alcohol, water, and glycerin as inactive ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Calea Zacatechichi's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: promote vivid or lucid dreams.
  • We looked for evidence on: Insomnia, Stress, Anxiety, Dream recall, Sleep quality.
  • The closest evidence on file: Calea Zacatechichi is rated "Insufficient Reliable Evidence To Rate" for Anxiety (Natural Medicines).
  • Also on file: Calea Zacatechichi is rated "Insufficient Reliable Evidence To Rate" for Insomnia, Stress.

The evidence on Calea zacatechichi isn't established in our data. It's been studied for headache, rheumatoid arthritis, insomnia, stress, and skin conditions, but we have insufficient reliable evidence to rate how well it works for any of these uses.

The evidence, ingredient by ingredient Calea Zacatechichi

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Calea zacatechichi has a long folk history but limited modern safety data. It's bitter tasting and can cause nausea, vomiting, and drowsiness in those who take it.

Some people in trials also reported somnolence and changes in sleep patterns, including less deep sleep. The safety data during pregnancy and breastfeeding isn't reliable enough — the facts advise against use in both.

Side effects, ingredient by ingredient Calea Zacatechichi

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Calea Zacatechichi.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 334 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, check whether you're on any CNS depressants (sedatives, sleep aids, some pain relievers) or antidiabetes drugs. Both can interact with Calea zacatechichi at Minor severity.

Use the medication checker on this page to run your prescriptions and over-the-counter drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Only minor medication interactions are documented, and safety information is well characterized.

Dream Herb may be worth considering if you're interested in traditional herbal use, but the evidence on whether it actually works isn't solid. If you take sedating medications or antidiabetes drugs, check with your pharmacist first.

Pregnant or breastfeeding? Skip it — there's not enough safety data.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Dream Herb, straight from the product label.

Brand Herbal Terra
Barcode (UPC) 1977490804380
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Mar 25, 2025
DSLD ID 326967
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Dream Herb by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
1977490804380
IngredientAmount% DV
Dream Herb Leaf, Stem Extract, Dry983 mg--

Other ingredients: Alcohol, Water, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz. of juice or water up to 4 times a day.

Precautions

We recommend to seek expert medical advice before taking. May have contraindications and cause adverse reaction.

Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications.

Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications. Keep out of the reach of children!

Do not use if you are allergic to any ingredients.

Storage

Store in a cool, dry, dark place.

FDA Disclaimer Statement

This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.

Formulation

cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.

Sugar free

Expertly extracted 100% natural Premium product

Organic alcohol

No artificial ingredients, color additives, fillers or binders.

Natural Gluten free

Formula

Calea zacatechichi

Organic alcohol

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

Made in USA

General Statements

Organic raw material.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Dream Herb by Herbal Terra label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Dream Herb label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Dream Herb by Herbal Terra

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Dream Herb Leaf, Stem Extract, Dry

Interacts with
334 drugs
983 mg per serving Form: Calea zacatechichi Leaf Extract, Dry, Calea zacatechichi Stem Extract, Dry

Calea zacatechichi, often called 'dream herb,' is a Mexican plant traditionally used to encourage vivid dreams and to treat digestive complaints and f...

Dream Herb Leaf, Stem Extract, Dry monograph & interactions

Other (inactive) ingredients: Alcohol, Water, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Dream Herb by Herbal Terra Drug Interactions

Want to check YOUR meds against Dream Herb?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
334Drugs
334 Minor

Ingredients driving the most interactions

Dream Herb Leaf, Stem Extract, Dry 334

Individual Drug Interactions

The ingredients in Dream Herb interact with 334 drugs. Click any drug to see the details.

1 of the 1 ingredient in Dream Herb interact with drugs. Each result below shows which ingredient is responsible. Dream Herb Leaf, Stem Extract, Dry

Each ingredient & the kinds of drugs it affects

For each ingredient in Dream Herb with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Dream Herb Leaf, Stem Extract, Dry2 drug types · 334 drugs

Antidiabetes Drugs

Theoretically, taking Calea zacatechichi with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that Calea zacatechichi lowers blood glucose levels. Theoretically, combining Calea zacatechichi with antidiabetes drugs might result in additive effects.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, Calea zacatechichi might increase the sedative effects of CNS depressants.
Calea zacatechichi can cause CNS depression in animals and humans.

Likelihood Possible Evidence D
Dream Herb Leaf, Stem Extract, Dry full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Dream Herb, from the product label.

Herbal Terra

See all Herbal Terra products
Name
Herbal Terra LLC
Phone Number
+18083857868
Web Address
herbalterra.com
Pharmacist Counseling Corner

Dream Herb by Herbal Terra: Common Questions

Does Dream Herb by Herbal Terra interact with any medications?
Yes. Based on its ingredients, Dream Herb has a known interaction with 334 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Dream Herb contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Dream Herb while pregnant or breastfeeding?
No — there isn't reliable safety data for Calea zacatechichi in pregnancy or while breastfeeding, so the facts advise against both. Talk with your doctor or pharmacist for personalized guidance.
What side effects might I experience?
It's bitter tasting and may cause nausea, vomiting, and drowsiness. Some trial participants also reported changes in sleep patterns, with less deep sleep. We have limited information on adverse effects overall.
Does Dream Herb actually work for insomnia or stress?
The evidence isn't established in our data. While it's used traditionally for these purposes, we have insufficient reliable evidence to rate how well it works.
What is Calea zacatechichi?
It's a plant extract with a long history of folk use. The leaf and stem are extracted and dried for this product.
Why would it interact with my diabetes or sleep medications?
Animal research shows Calea zacatechichi lowers blood glucose and causes sedation. If you combine it with your medications, the effects could add up and become stronger than either one alone.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Dream Herb is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Dream Herb label
Go deeper

The Full Monographs Behind Dream Herb’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Calea Zacatechichi

Interacts with 334 drugs

Calea zacatechichi, often called 'dream herb,' is a Mexican plant traditionally used to encourage vivid dreams and to treat digestive complaints and fever. Human research is very limited, so...

Read the full Calea Zacatechichi monograph →
Sources

Sources & How We Checked

Dream Herb's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Calea Zacatechichi 2 references
  1. Mayagoitia, L., Diaz, J. L., Contreras, C. M. Psychopharmacologic analysis of an alleged oneirogenic plant: Calea zacatechichi. J Ethnopharmacol. 1986;18:229-243. PubMed
  2. Roman, Ramos R., Alarcon-Aguilar, F., Lara-Lemus, A., and Flores-Saenz, J. L. Hypoglycemic effect of plants used in Mexico as antidiabetics. Arch.Med.Res 1992;23:59-64.

See these in context on the Calea Zacatechichi monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team