Ellura Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Ellura against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Ellura is a dietary supplement by Solv Wellness with 1 active ingredient. Its ingredients are commonly taken for urinary tract infection prevention, bladder health, antioxidant support.Based on those ingredients, 712 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Cranberry juice concentrate extract powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Ellura by Solv Wellness
Ask about any prescription or over-the-counter medication and we check it for interactions with Ellura by Solv Wellness — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Ellura by Solv Wellness
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Ellura contains a single active ingredient: cranberry juice concentrate extract powder, which delivers the plant compounds that cranberry is known for. The capsule also includes inactive ingredients — mannitol, magnesium stearate, silicon dioxide, and hydroxypropylmethylcellulose — which are fillers and binders used to hold the capsule together and help it dissolve.
Does it work?
Moderate evidence
Cranberry extract in Ellura is possibly effective for urinary tract infections (UTIs) — that's the one use where research supports a benefit. For other conditions listed here — age-related cognitive decline, benign prostate enlargement, cancer prevention, liver disease, and chronic fatigue — there isn't enough reliable evidence to say whether it works.
If you're taking it for UTI prevention or treatment, talk with your doctor about how it fits into your care plan.
How safe is it?
Well-documented data
Cranberry is generally well tolerated, and normal food amounts are likely fine. The catch is that this product is a concentrated supplement, not just juice — concentrated doses haven't been studied as much, so check with your provider before starting.
Diarrhea and stomach discomfort are the most common side effects; some people report nausea, vomiting, or in rare cases, skin itching. Very large doses can cause more pronounced digestive upset, especially in young children.
Meds to double-check
Moderate interaction found
Before taking Ellura, double-check if you use blood thinners like warfarin — cranberry may increase bleeding risk. Also flag any cholesterol-lowering drugs (especially atorvastatin), blood pressure medications like nifedipine, or pain relievers processed by your liver.
These Moderate and Minor interactions are documented in our data for cranberry.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Ellura may help with UTI prevention, but it's not a substitute for medical treatment of an actual infection. The main thing to watch is whether you take blood thinners, cholesterol drugs, or blood pressure medications — cranberry can interact with those.
Talk with your doctor or pharmacist about whether this product fits your health picture before you start.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 21, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Ellura, straight from the product label.
| Brand | Solv Wellness |
|---|---|
| Net contents | 90 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jul 21, 2022 |
| DSLD ID | 274024 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Ellura by Solv Wellness, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proanthocyanidins | 36 mg | -- |
| Cranberry juice concentrate extract powder | 206 mg | -- |
Other ingredients: Mannitol, Magnesium Stearate, Silicon Dioxide, Hydroxypropylmethylcellulose
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
For urinary tract health
Contains no GMOs, artificial preservatives, colors or sweeteners and no corn, dairy, soy, wheat yeast or gluten
Formula
36 mg soluble PAC (proanthocyanidins) from concentrated cranberry juice extract
Ellura starts working within hours to help maintain a clean urinary tract. Contains clinically-proven 36 mg of soluble PAC (measured by DMAC/A2 method).
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: Take 1 capsule daily with water. For additional support, take 2 daily for several days. With sex: Take 2 before or after, then 2 the next day.
Precautions
Caution: Consult health care provider before use if you have a red fruit allergy.
Keep out of reach of children.
Storage
Store at room temperature (15 degrees - 30 degrees C/ 59 degrees - 86 degrees F). Avoid prolonged exposure to direct sunlight and excessive moisture.
Brand IP Statement(s)
Ellura is a registered trademark of Nutrax LTD. Gikacran is a registered trademark of Pharmatoka S.A.S.
FDA Disclaimer Statement
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Ellura by Solv Wellness label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Ellura by Solv Wellness
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.
Proanthocyanidins
Other (inactive) ingredients: Mannitol, Magnesium Stearate, Silicon Dioxide, Hydroxypropylmethylcellulose. These complete the product’s ingredient list but are not active constituents.
Ellura by Solv Wellness Drug Interactions
HelloPharmacist Interaction Report
Ellura by Solv Wellness contains cranberry juice concentrate extract powder, which has documented interactions with a number of medications.
The most serious concern is with blood thinners like warfarin (Coumadin) — cranberry may increase warfarin levels and bleeding risk, though the evidence is mixed. Case reports have linked cranberry juice to higher blood-thinning effects, but clinical studies show conflicting results.
Read the full breakdown — every affected drug type, severity by severity
Cranberry in this product may also raise levels of cholesterol-lowering drugs (CYP3A4 substrates), including atorvastatin (Lipitor) — one case report documented muscle breakdown, liver injury, and back pain when a patient combined atorvastatin with large amounts of cranberry juice. Blood pressure medications like nifedipine (Procardia) may also be affected; animal studies suggest cranberry could increase nifedipine levels by up to 60 percent.
Additionally, pain relievers and other drugs processed the same way (CYP2C9 substrates) carry a Minor interaction risk with conflicting evidence in the research.
Additionally, the product contains proanthocyanidins as its other active ingredient, but we were unable to check whether it has interactions — the data we hold doesn't break out its individual component parts. Altogether, these interactions span 713 individual medications.
Run your exact prescriptions through the medication checker on this page before you start. If you take warfarin, any statin, nifedipine, or other blood pressure or pain medications, check with your doctor or pharmacist first.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Ellura?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Ellura interact with 712 drugs. Click any drug to see the details.
1 of the 1 ingredient in Ellura interact with drugs. Each result below shows which ingredient is responsible. Cranberry juice concentrate extract powder
AbrocitinibCibinqo
How Abrocitinib interacts with Ellura — through 1 ingredient. Tap an ingredient for the detail:
Cranberry Juice Concentrate Extract PowderCytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Cranberry Juice Concentrate Extract Powder + Abrocitinib interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Ellura — through 1 ingredient. Tap an ingredient for the detail:
Cranberry Juice Concentrate Extract PowderCytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Cranberry Juice Concentrate Extract Powder + Acetaminophen, Ibuprofen interactionAerosphere Budesonide, Formoterol Fumarate, GlycopyrrolateBreztri
How Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interacts with Ellura — through 1 ingredient. Tap an ingredient for the detail:
Cranberry Juice Concentrate Extract PowderCytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Cranberry Juice Concentrate Extract Powder + Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interactionAgomelatineValdoxan
How Agomelatine interacts with Ellura — through 1 ingredient. Tap an ingredient for the detail:
Cranberry Juice Concentrate Extract PowderCytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Cranberry Juice Concentrate Extract Powder + Agomelatine interactionAzilsartanEdarbi
How Azilsartan interacts with Ellura — through 1 ingredient. Tap an ingredient for the detail:
Cranberry Juice Concentrate Extract PowderCytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Cranberry Juice Concentrate Extract Powder + Azilsartan interactionAzilsartan, ChlorthalidoneEdarbyclor
How Azilsartan, Chlorthalidone interacts with Ellura — through 1 ingredient. Tap an ingredient for the detail:
Cranberry Juice Concentrate Extract PowderCytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Cranberry Juice Concentrate Extract Powder + Azilsartan, Chlorthalidone interactionBudesonide, FormoterolSymbicort
How Budesonide, Formoterol interacts with Ellura — through 1 ingredient. Tap an ingredient for the detail:
Cranberry Juice Concentrate Extract PowderCytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Cranberry Juice Concentrate Extract Powder + Budesonide, Formoterol interactionBupivacaine, MeloxicamZynrelef Kit
How Bupivacaine, Meloxicam interacts with Ellura — through 1 ingredient. Tap an ingredient for the detail:
Cranberry Juice Concentrate Extract PowderCytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Cranberry Juice Concentrate Extract Powder + Bupivacaine, Meloxicam interactionCarvedilolCoreg, Coreg CR
How Carvedilol interacts with Ellura — through 1 ingredient. Tap an ingredient for the detail:
Cranberry Juice Concentrate Extract PowderCytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Cranberry Juice Concentrate Extract Powder + Carvedilol interactionCelecoxibCelebrex, Elyxyb
How Celecoxib interacts with Ellura — through 1 ingredient. Tap an ingredient for the detail:
Cranberry Juice Concentrate Extract PowderCytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Cranberry Juice Concentrate Extract Powder + Celecoxib interactionDiclofenacZorvolex
How Diclofenac interacts with Ellura — through 1 ingredient. Tap an ingredient for the detail:
Cranberry Juice Concentrate Extract PowderCytochrome P450 2c9 (cyp2c9) Substrates, Diclofenac (voltaren, Others) Minor
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Cranberry Juice Concentrate Extract Powder + Diclofenac interactionDiclofenac PotassiumCambia, Cataflam, Cataflam IR, Voltaren Rapide, Voltarol Rapid
How Diclofenac Potassium interacts with Ellura — through 1 ingredient. Tap an ingredient for the detail:
Cranberry Juice Concentrate Extract PowderCytochrome P450 2c9 (cyp2c9) Substrates, Diclofenac (voltaren, Others) Minor
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Cranberry Juice Concentrate Extract Powder + Diclofenac Potassium interactionDiclofenac SodiumAcoflam, Acoflam 75 SR, Acoflam Retard, Defenac, Defenac Retard, Defenac SR +40 more
How Diclofenac Sodium interacts with Ellura — through 1 ingredient. Tap an ingredient for the detail:
Cranberry Juice Concentrate Extract PowderDiclofenac (voltaren, Others), Cytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
Theoretically, cranberry might modestly increase the levels and adverse effects of diclofenac.
Read the full Cranberry Juice Concentrate Extract Powder + Diclofenac Sodium interactionDiclofenac Sodium, MisoprostolArthrotec 50, Arthrotec 75
How Diclofenac Sodium, Misoprostol interacts with Ellura — through 1 ingredient. Tap an ingredient for the detail:
Cranberry Juice Concentrate Extract PowderCytochrome P450 2c9 (cyp2c9) Substrates, Diclofenac (voltaren, Others) Minor
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Cranberry Juice Concentrate Extract Powder + Diclofenac Sodium, Misoprostol interactionDiclofenac EpolamineFlector, Licart
How Diclofenac Epolamine interacts with Ellura — through 1 ingredient. Tap an ingredient for the detail:
Cranberry Juice Concentrate Extract PowderDiclofenac (voltaren, Others), Cytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
Theoretically, cranberry might modestly increase the levels and adverse effects of diclofenac.
Read the full Cranberry Juice Concentrate Extract Powder + Diclofenac Epolamine interactionDiphenhydramine Hydrochloride, Naproxen SodiumAleve PM
How Diphenhydramine Hydrochloride, Naproxen Sodium interacts with Ellura — through 1 ingredient. Tap an ingredient for the detail:
Cranberry Juice Concentrate Extract PowderCytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Cranberry Juice Concentrate Extract Powder + Diphenhydramine Hydrochloride, Naproxen Sodium interactionFamotidine, IbuprofenDuexis
How Famotidine, Ibuprofen interacts with Ellura — through 1 ingredient. Tap an ingredient for the detail:
Cranberry Juice Concentrate Extract PowderCytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Cranberry Juice Concentrate Extract Powder + Famotidine, Ibuprofen interactionFluoxetineProzac, Sarafem
How Fluoxetine interacts with Ellura — through 1 ingredient. Tap an ingredient for the detail:
Cranberry Juice Concentrate Extract PowderCytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Cranberry Juice Concentrate Extract Powder + Fluoxetine interactionFlurbiprofenAnsaid, Flurbiprofen, Flurprofen, Froben, Froben SR, Ocufen
How Flurbiprofen interacts with Ellura — through 1 ingredient. Tap an ingredient for the detail:
Cranberry Juice Concentrate Extract PowderCytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Cranberry Juice Concentrate Extract Powder + Flurbiprofen interactionFluvastatinLescol, Lescol XL
How Fluvastatin interacts with Ellura — through 1 ingredient. Tap an ingredient for the detail:
Cranberry Juice Concentrate Extract PowderCytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Cranberry Juice Concentrate Extract Powder + Fluvastatin interactionFomoterolForadil
How Fomoterol interacts with Ellura — through 1 ingredient. Tap an ingredient for the detail:
Cranberry Juice Concentrate Extract PowderCytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Cranberry Juice Concentrate Extract Powder + Fomoterol interactionFormoterolAtimos Modulite, Foradil Aerolizer, Foradil Certihaler, Oxis Turbohaler, Perforomist
How Formoterol interacts with Ellura — through 1 ingredient. Tap an ingredient for the detail:
Cranberry Juice Concentrate Extract PowderCytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Cranberry Juice Concentrate Extract Powder + Formoterol interactionFormoterol Fumarate, GlycopyrrolateBevespi Aerosphere
How Formoterol Fumarate, Glycopyrrolate interacts with Ellura — through 1 ingredient. Tap an ingredient for the detail:
Cranberry Juice Concentrate Extract PowderCytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Cranberry Juice Concentrate Extract Powder + Formoterol Fumarate, Glycopyrrolate interactionFosphenytoinCerebyx
How Fosphenytoin interacts with Ellura — through 1 ingredient. Tap an ingredient for the detail:
Cranberry Juice Concentrate Extract PowderCytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Cranberry Juice Concentrate Extract Powder + Fosphenytoin interactionFosphenytoin SodiumSesquient
How Fosphenytoin Sodium interacts with Ellura — through 1 ingredient. Tap an ingredient for the detail:
Cranberry Juice Concentrate Extract PowderCytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Cranberry Juice Concentrate Extract Powder + Fosphenytoin Sodium interactionGliclazideDiamicron
How Gliclazide interacts with Ellura — through 1 ingredient. Tap an ingredient for the detail:
Cranberry Juice Concentrate Extract PowderCytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Cranberry Juice Concentrate Extract Powder + Gliclazide interactionGlimepirideAmaryl
How Glimepiride interacts with Ellura — through 1 ingredient. Tap an ingredient for the detail:
Cranberry Juice Concentrate Extract PowderCytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Cranberry Juice Concentrate Extract Powder + Glimepiride interactionGlipizideGlucotrol, Glucotrol XL
How Glipizide interacts with Ellura — through 1 ingredient. Tap an ingredient for the detail:
Cranberry Juice Concentrate Extract PowderCytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Cranberry Juice Concentrate Extract Powder + Glipizide interactionGlipizide, MetforminMetaglip
How Glipizide, Metformin interacts with Ellura — through 1 ingredient. Tap an ingredient for the detail:
Cranberry Juice Concentrate Extract PowderCytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Cranberry Juice Concentrate Extract Powder + Glipizide, Metformin interactionGlyburideAlbert Glyburide, Diabeta, Glycron, Glynase, Glynase PresTab, Micronase +1 more
How Glyburide interacts with Ellura — through 1 ingredient. Tap an ingredient for the detail:
Cranberry Juice Concentrate Extract PowderCytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates.
Read the full Cranberry Juice Concentrate Extract Powder + Glyburide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Ellura with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Cranberry juice concentrate extract powder
Atorvastatin (Lipitor)
Theoretically, cranberry might increase levels and adverse effects of atorvastatin.
In one case report, a patient taking atorvastatin experienced upper back pain, rhabdomyolysis, and abnormal liver function after drinking cranberry juice 16 ounces daily for 2 weeks. Theoretically, this may have been caused by inhibition of cytochrome P450 3A4 (CYP3A4) enzymes by cranberry juice, as atorvastatin is a CYP3A4 substrate. Creatinine kinase and liver enzymes normalized within 2 weeks of stopping cranberry juice. Patients taking atorvastatin should avoid large quantities of cranberry juice.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, cranberry might increase the levels and adverse effects of CYP3A4 substrates.
A case of upper back pain, rhabdomyolysis, and abnormal liver function has been reported for a patient taking atorvastatin, a CYP3A4 substrate, in combination with cranberry juice 16 ounces daily for 2 weeks. Creatinine kinase and liver enzymes normalized within 2 weeks of stopping cranberry juice. Also, animal research suggests that cranberry juice, administered intraduodenally 30 minutes prior to nifedipine, a CYP3A4 substrate, inhibits nifedipine metabolism and increases the area under the concentration-time curve by 1.6-fold compared to control.
Nifedipine (Procardia)
Theoretically, cranberry might increase the levels and adverse effects of nifedipine.
Animal research suggests that cranberry juice, administered intraduodenally 30 minutes prior to nifedipine treatment, inhibits nifedipine metabolism and increases the area under the concentration-time curve by 1.6-fold compared to control. This interaction has not been reported in humans.
Warfarin (Coumadin)
Theoretically, cranberry might increase the levels and adverse effects of warfarin. However, research is conflicting.
There is contradictory evidence about the effect of cranberry juice on warfarin. Case reports have linked cranberry juice consumption to increases in the international normalized ratio (INR) in patients taking warfarin, resulting in severe spontaneous bleeding and excessive postoperative bleeding. Daily consumption of cranberry sauce for one week has also been linked to an increase in INR in one case report. In a small study in healthy young males, taking a high dose of 3 grams of cranberry juice concentrate capsules, equivalent to 57 grams of fruit daily, for 2 weeks produced a 30% increase in the area under the INR-time curve after a single 25-mg dose of warfarin. However, 3 very small clinical studies in patients stabilized on warfarin reported that cranberry juice 250 mL once or twice daily for 7 days (27% cranberry juice or pure cranberry juice) or 240 mL once daily for 14 days does not significantly increase INR or affect plasma warfarin levels. The reasons for these discrepant findings are unclear. It is possible that the form and dose of cranberry may play a role, as cranberry extracts and juices contain different constituents. Additionally, an in vitro study evaluating 5 different cranberry juices found varying effects, with only a cranberry concentrate, and not diluted cranberry juices, inhibiting CYP2C9. However, this concentrate did not inhibit CYP2C9 activity in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates. However, research is conflicting.
There is contradictory evidence about the effect of cranberry on CYP2C9 enzymes. In vitro evidence suggests that flavonoids in cranberry inhibit CYP2C9 enzymes. However, clinical research shows that cranberry juice does not significantly affect the levels, metabolism, or elimination of the CYP2C9 substrates flurbiprofen or diclofenac. Also, in patients stabilized on warfarin, drinking cranberry juice 250 mL daily for 7 days does not significantly increase the anticoagulant activity of warfarin, a CYP2C9 substrate. Additional pharmacokinetic research shows that cranberry juice does not increase peak plasma concentrations or area under the concentration-time curve of warfarin.
Diclofenac (Voltaren, Others)
Theoretically, cranberry might modestly increase the levels and adverse effects of diclofenac.
In vitro evidence suggests that cranberry juice inhibits diclofenac metabolism by human liver microsomes. However, drinking cranberry juice does not seem to affect diclofenac metabolism in humans.
Brand information
Manufacturer and brand details for Ellura, from the product label.
Solv Wellness
See all Solv Wellness products- Name
- Solv Wellness, LLC
- City
- Atlanta
- State
- GA
- ZipCode
- 30318
- Phone Number
- 877.421.7160
- Web Address
- Ellura.com
Ellura by Solv Wellness: Common Questions
Does Ellura by Solv Wellness interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is Ellura safe to take while pregnant or breastfeeding?
What's the difference between this and just drinking cranberry juice?
Can Ellura actually prevent UTIs?
What side effects should I watch for?
Is this a substitute for antibiotics if I have a UTI?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Ellura is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Ellura’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Ellura's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 33 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Cranberry 33 references
- Anon. Possible interaction between warfarin and cranberry juice. Current Problems in Pharmacovigilance 2003;29:8. PubMed
- Greenblatt DJ, von Moltke LL, Perloff ES, et al. Interaction of flurbiprofen with cranberry juice, grape juice, tea, and fluconazole: in vitro and clinical studies. Clin Pharmacol Ther 2006;79:125-33. PubMed
- Hodek P, Trefil P, Stiborova M. Flavonoids-potent and versatile biologically active compounds interacting with cytochromes P450. Chem Biol Interact 2002;139:1-21.. PubMed
- Grant P. Warfarin and cranberry juice: An interaction? J Heart Valve Dis 2004;13:25-6.
- Suvarna R, Pirmohamed M, Henderson L. Possible interaction between warfarin and cranberry juice. BMJ 2003;327:1454. PubMed
- Li Z, Seeram NP, Carpenter CL, et al. Cranberry does not affect prothrombin time in male subjects on warfarin. J Am Diet Assoc 2006;106:2057-61. PubMed
- Lilja JJ, Backman JT, Neuvonen PJ. Effects of daily ingestion of cranberry juice on the pharmacokinetics of warfarin, tizanidine, and midazolam - probes of CYP2C9, CYP1A2 and CYP3A4. Clin Pharmacol The 2007:81:833-9. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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