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Dietary supplement

Enula Ingredients & Drug Interactions

by NutraMedix

Enula label
See full label image
Liquid Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Enula against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Enula is a dietary supplement by NutraMedix with 2 active ingredients. Its ingredients are commonly taken for cough and bronchitis, asthma symptoms, loosening mucus (expectorant).Based on those ingredients, 346 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Elecampane Root Extract, Jalap root extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Enula by NutraMedix

Ask about any prescription or over-the-counter medication and we check it for interactions with Enula by NutraMedix — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Enula by NutraMedix

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (1.50 mL) without saying how much of each component you get.

Enula is a 2-ingredient liquid supplement built around a proprietary blend. The two active ingredients are elecampane root extract and jalap root extract, delivered in a base of water and ethanol (a standard carrier for herbal tinctures and extracts).

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Immune and microbial support.
  • We looked for evidence on: Cough, Bronchitis, Respiratory infections, Mucus clearance.
  • The closest evidence on file: Elecampane is rated "Insufficient Reliable Evidence To Rate" for Cough (Natural Medicines).

The evidence we hold does not establish that elecampane works for acne or cough — both ratings are insufficient reliable evidence. No effectiveness data is on file for jalap in this product.

The evidence, ingredient by ingredient Elecampane Jalap

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Elecampane is generally used in small amounts and is generally well tolerated, but it can trigger allergic reactions and stomach upset, especially in people sensitive to the ragweed family of plants. At high oral doses, it may cause diarrhea, vomiting, and other serious effects.

The safety data advises against elecampane during pregnancy and breastfeeding. Jalap is a harsh purgative known to cause severe cramping and dehydration, and it is generally not recommended for routine use.

The safety data advises against it during pregnancy and breastfeeding.

Side effects, ingredient by ingredient Elecampane Jalap

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Elecampane, Jalap.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; heart-rhythm medications; lithium.
  • For scale: 346 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take Enula, double-check any other laxatives or stool softeners you're on (major interaction with jalap), then water pills or diuretics, blood thinners like warfarin, the heart drug digoxin, lithium, and sedating medications like sleep aids or anxiety drugs. These are the medication types with documented interactions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.

This product combines two potent plant extracts with known interactions and safety limits. If you take any blood thinner, water pill, heart medication, or sedating drug, check your exact medications with the tool on this page before starting.

Talk to your pharmacist or doctor — especially if you're pregnant, nursing, or considering long-term use.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Enula, straight from the product label.

Brand NutraMedix
Barcode (UPC) 728650026576
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Jul 24, 2025
DSLD ID 334032
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Enula by NutraMedix, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Drop(s)
Maximum serving Sizes:
30 Drop(s)
Servings per container
20
UPC/BARCODE
728650026576
IngredientAmount% DV
Proprietary Blend1.5 mL--
Elecampane Root Extract0 NP--
Jalap root extract0 NP--

Other ingredients: Water, Ethanol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Shake well before each use: Put 1 to 30 drops in 4 oz (120 mL) of water and wait one minute before drinking. Start with 1 drop (30min. before meals) increasing slowly up to 30 drops 2-4 times per day or as directed by your physician.

Precautions

Do not use if pregnant or nursing.

Stop use if adverse reactions develop.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Immune/Microbial support

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Enula by NutraMedix label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Enula label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Enula by NutraMedix

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Drop(s) Dosage formLiquid Servings per container20 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

1.5 mL per serving

Other (inactive) ingredients: Water, Ethanol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Enula by NutraMedix Drug Interactions

Want to check YOUR meds against Enula?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
346Drugs
21 Major 325 Moderate

Ingredients driving the most interactions

Elecampane Root Extract 248
Jalap root extract 100

Individual Drug Interactions

The ingredients in Enula interact with 346 drugs. Click any drug to see the details.

2 of the 2 ingredients in Enula interact with drugs. Each result below shows which ingredient is responsible. Elecampane Root Extract Jalap root extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Enula with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Elecampane Root Extract1 drug type · 248 drugs

Cns Depressants

Theoretically, elecampane may cause additive sedative effects when taken with CNS depressants.
Elecampane might have sedative effects.

Likelihood Possible Evidence D
Elecampane Root Extract full monograph & interactions

Jalap root extract5 drug types · 100 drugs

Stimulant Laxatives

Jalap has stimulant laxative effects. Concomitant use of jalap with other laxatives may lead to electrolyte and fluid depletion.

Likelihood Probable Evidence D
Digoxin (Lanoxin)

Jalap has diuretic and stimulant laxative effects. Theoretically, overuse or abuse of jalap might increase potassium depletion and increase the risk for toxicity with cardiac glycoside drugs.

Likelihood Possible Evidence D
Diuretic Drugs

Jalap has diuretic effects. Overuse of jalap might compound diuretic-induced potassium loss. There is some concern that people taking jalap along with potassium depleting diuretics might have an increased risk for hypokalemia.
Some diuretics that can deplete potassium include chlorothiazide (Diuril), chlorthalidone (Thalitone), furosemide (Lasix), hydrochlorothiazide (HCTZ, Hydrodiuril, Microzide), and others.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Jalap has stimulant laxative effects. In some people jalap can cause diarrhea. Diarrhea can increase the effects of warfarin, increase international normalized ratio (INR), and increase the risk of bleeding. Advise patients who take warfarin not to take excessive amounts of jalap.

Likelihood Possible Evidence D
Lithium

Jalap has diuretic effects. Theoretically, due to these potential diuretic effects, jalap might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Possible Evidence D
Jalap root extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Enula, from the product label.

NutraMedix

See all NutraMedix products
Name
NutraMedix
City
Jupiter
State
Florida
ZipCode
33458
Phone Number
561-745-2917
Web Address
www.nutramedix.com
Pharmacist Counseling Corner

Enula by NutraMedix: Common Questions

Does Enula by NutraMedix interact with any medications?
Yes. Based on its ingredients, Enula has a known interaction with 346 medications, including 21 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Enula contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Enula if I'm pregnant?
No — the safety data advises against both ingredients during pregnancy. Talk with your doctor or pharmacist if you're pregnant or planning to become pregnant.
Can I take Enula if I'm breastfeeding?
No — the safety data advises against both ingredients while breastfeeding. Check with your doctor or pharmacist for alternatives safe during nursing.
What are elecampane and jalap used for in this product?
Elecampane is traditionally used for cough and acne, though the evidence we hold is insufficient to confirm either. Jalap is a strong laxative (purgative) traditionally used to stimulate bowel movements.
What side effects should I watch for?
Elecampane may cause allergic reactions and stomach upset; at high doses it can cause diarrhea, vomiting, or spasms. Jalap commonly causes severe cramping and can lead to dehydration and electrolyte loss.
Can I take Enula long-term?
Jalap is a harsh purgative and is generally not recommended for routine or long-term use because of the risk of cramping, dehydration, and electrolyte imbalance. Talk with your pharmacist about duration.
Is Enula safe if I'm taking water pills?
No — jalap has documented interactions with diuretic drugs. Using them together may compound potassium loss and increase the risk of low blood potassium. Do not take this product if you're on a diuretic without checking first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Enula label
Go deeper

The Full Monographs Behind Enula’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Elecampane

Interacts with 248 drugs

Elecampane is a traditional herb used mainly for coughs and other respiratory complaints, and as a bitter for digestion. Modern human evidence is very limited, so it should be seen as a folk...

Read the full Elecampane monograph → Herb & supplement monograph

Jalap

Interacts with 100 drugs

Jalap is a powerful traditional laxative made from the root of a Mexican morning-glory plant. It is rarely used today because it can cause violent diarrhea, cramping, and dehydration, and sa...

Read the full Jalap monograph →
Sources

Sources & How We Checked

Enula's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Elecampane 5 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Lamminpaa A, Estlander T, Jolanki R, Kanerva L. Occupational allergic contact dermatitis caused by decorative plants. Contact Dermatitis 1996;34:330-5. PubMed
  4. Pazzaglia, M., Venturo, N., Borda, G., and Tosti, A. Contact dermatitis due to a massage liniment containing Inula helenium extract. Contact Dermatitis 1995;33(4):267.
  5. Aalto-Korte, K., Alanko, K., Kuuliala, O., and Jolanki, R. Late reactions in patch tests: a 4-year review from a clinic of occupational dermatology. Contact Dermatitis 2007;56(2):81-86. PubMed

See these in context on the Elecampane monograph →

Jalap 1 reference
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.

See these in context on the Jalap monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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