EVP 3D Raspberry Lemonade Ingredients & Drug Interactions
by Evogen
What is this page for?
First and foremost: checking EVP 3D Raspberry Lemonade against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
EVP 3D Raspberry Lemonade is a dietary supplement by Evogen with 10 active ingredients. Its ingredients are commonly taken for replacing fluids and electrolytes, preventing dehydration during exercise or illness, treating low blood sodium (under medical care).Based on those ingredients, 753 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lion's Mane extract, Dimethylaminoethanol, Sodium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against EVP 3D Raspberry Lemonade by Evogen
Ask about any prescription or over-the-counter medication and we check it for interactions with EVP 3D Raspberry Lemonade by Evogen — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of EVP 3D Raspberry Lemonade by Evogen
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
EVP 3D Raspberry Lemonade contains 10 active ingredients: coconut water powder, L-tyrosine, creatine anhydrous, dimethylaminoethanol (deanol), beta-alanine, L-citrulline, sodium, arginine nitrate, and lion's mane extract. These are grouped in three proprietary blends — EVP-3D N.O.
Performance Matrix, EVP-3D Hydration Strength Matrix, and EVP-3D Focus Matrix — whose individual component amounts aren't disclosed on the label. The product also contains inactive ingredients including malic acid, citric acid, calcium silicate, silica, natural and artificial flavor, sucralose, acesulfame potassium, and red beet powder.
Does it work?
Moderate evidence
Evidence for most ingredients in this product is limited. L-tyrosine is possibly effective for cognitive function and memory, but the others show either insufficient evidence or mixed results.
Creatine is possibly effective for muscle strength and athletic performance in healthy individuals. Beta-alanine is possibly effective for athletic and physical performance.
L-citrulline is possibly effective for athletic performance. Lion's mane extract, coconut water, deanol, and sodium all lack established evidence for the uses typically claimed in workout products.
Coconut water, L-tyrosine, and creatine have been studied for other conditions, but that evidence doesn't apply here.
How safe is it?
Well-documented data
Most ingredients are generally well tolerated in healthy adults, but each carries cautions. Coconut water is likely safe in pregnancy and lactation at normal food amounts, but concentrated supplement doses aren't well studied.
L-tyrosine and beta-alanine lack adequate safety data and should be avoided during pregnancy and breastfeeding. Creatine is best avoided in pregnancy and during breastfeeding due to insufficient safety data; those with kidney problems should be cautious.
Deanol and lion's mane extract both lack sufficient safety data and should be avoided during pregnancy and breastfeeding. L-citrulline's long-term safety isn't fully studied; it should be avoided as a supplement during pregnancy and breastfeeding.
Sodium at high intakes is linked to high blood pressure and kidney stress, especially in those with existing cardiovascular or kidney disease. Common side effects from beta-alanine include harmless tingling and flushing of the skin; creatine can cause water retention, dehydration, diarrhea, and muscle cramps; deanol may cause abdominal cramps, nausea, diarrhea, and drowsiness; and lion's mane may cause gastrointestinal upset and nausea.
Meds to double-check
Moderate interaction found
Double-check this product with your doctor or pharmacist if you take levodopa (Parkinson's medication), thyroid hormone replacements, blood pressure medications, erectile dysfunction drugs, corticosteroids, lithium, HIV medications, bowel-prep drugs, blood thinners or antiplatelet drugs, antidiabetes drugs, or immunosuppressants. Sodium appears twice in this formula and has the broadest interaction list.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This is a workout supplement formulated for athletic performance and focus, but evidence is limited for most ingredients. If you take medications for Parkinson's disease, thyroid function, blood pressure, erectile dysfunction, mood disorders, immune conditions, or blood thinning, check each one with your doctor or pharmacist before starting this product.
Those with kidney disease, high blood pressure, or cardiovascular disease should discuss sodium intake and creatine use with their healthcare provider. Pregnant and breastfeeding people should talk with their doctor before use.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 9 of 10 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 16, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about EVP 3D Raspberry Lemonade, straight from the product label.
| Brand | Evogen |
|---|---|
| Barcode (UPC) | 817189027755 |
| Net contents | 17.1 Ounce(s); 1.06 Pound(s) |
| Market status | On market |
| Date entered into DSLD | Jun 16, 2022 |
| DSLD ID | 264878 |
| Product type | Other Combinations |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for EVP 3D Raspberry Lemonade by Evogen, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Coconut Water powder | 1000 mg | -- |
| L-Tyrosine | 1000 mg | -- |
| Creatine Anhydrous | 2500 mg | -- |
| Dimethylaminoethanol | 600 mg | -- |
| Beta-Alanine | 3200 mg | -- |
| L-Citrulline | 6000 mg | -- |
| Sodium | 80 mg | 3% |
| Arginine Nitrate | 2000 mg | -- |
| EVP-3D N.O. Performance Matrix | 0 NP | -- |
| EVP-3D Hydration Strength Matrix | 0 NP | -- |
| EVP-3D Focus Matrix | 0 NP | -- |
| Lion's Mane extract | 500 mg | -- |
| Sodium | 40 mg | 2% |
Other ingredients: Malic Acid, Citric Acid, Calcium Silicate, Silica, Natural and Artificial flavor, Sucralose, Acesulfame Potassium, Red Beet powder
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Stim-free
Elite pump and training ignitor Maximum > Pump intensity > Mental focus > Muscle vascularity
EVP-30 is the evolution of the original, hardcore, non-stim, pre-workout solution and will take your workouts to the next level by maximizing blood flow and pump intensity to levels you never imagined. Made in the USA with domestic & international ingredients
No artificial colors
FDA Statement of Identity
Dietary Supplement
Brand IP Statement(s)
Patented NO3-T Nitrate technology
Copyright 2020 Evogen, Inc. All rights reserved. Evogen and EVP are registered trademarks of Evogen Nutrition. NO3-T is a registered trademark of ThermoLife International, LLC., this mark covers the use of one or more patents listed as www.NO3-T.com/patents. NO3-T Nitrate Technology
Formula
Raspberry Lemonade Natural and artificial flavors
Seals/Symbols
Manufactured in a FDA & GMP Inspected Facility
The Pro Creator Designed by Hany Rambod Seal of Quality & Potency
Precautions
Allergen warning: Tree nut (coconut). Manufactured in a facility that also processes peanuts, wheat & eggs.
Warning: Not for use by individuals under the age of 18. Keep out of reach of children.
Do not use if pregnant, expect to become pregnant or nursing. Do not use if you have a medical condition or are taking any prescription medication. Do not use if you are currently taking nitrates for chest pain or if you are taking medication used to treat erectile dysfunction such as PDE-5 inhibitors, antidepressants that are classified as monoamine oxidase inhibitors (MAOIs), or any other medications.
Always consult a physician prior to using this product or any other dietary supplement product, especially if you are unaware of your current health condition or have any pre-exiting medical condition. If you experience any other adverse reaction discontinue use immediately and consult a physician. Discontinue use two weeks prior to surgery. Do not exceed recommended serving. Do not use if safety seal is broken or missing. Warning: Consuming this product can expose you to chemicals including lead, which is known to the state of California to cause birth defects or other reproductive harm. For more information go to www.P65warnings.ca.gov/food
Storage
To maximize freshness, user may refrigerate after opening.
Store in a cool, dry place away from sunlight, moisture, and heat.
General Statements
Filled by weight, not by volume. Contents may settle. Follow us @EvogenNutrition #EvogenElite
Nicknamed "The Pro Creator," Hany Rambod has been constructing championship-winning physiques for over 20 years while using his ground-breaking FST-7 training system. Rambod prides himself on bringing only quality innovations to his customers around the world.
Servings Per Container: About 40/20
Suggested/Recommended/Usage/Directions
Directions for EVP-3D: Mix 1 serving (1 scoop) with 8-10 fl. oz. of cold water 20-30 minutes before training. During your workout and throughout the day, it is recommended that you drink plenty of water. Some individuals may experience a tingling sensation, which is attributed to beta alanine.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
EVP 3D Raspberry Lemonade by Evogen label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in EVP 3D Raspberry Lemonade by Evogen
These are the 10 active ingredients this product is made of. Select any to open its full monograph.
Serving size12.1 Gram(s) Dosage formPowder Servings per container20 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Sodium
Interacts with205 drugs
Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...
Sodium monograph & interactionsEVP-3D N.O. Performance Matrix
- › Beta-Alanine
- › L-Citrulline
- › Arginine Nitrate
EVP-3D Hydration Strength Matrix
EVP-3D Focus Matrix
Sodium
Interacts with205 drugs
Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...
Sodium monograph & interactionsOther (inactive) ingredients: Malic Acid, Citric Acid, Calcium Silicate, Silica, Natural and Artificial flavor, Sucralose, Acesulfame Potassium, Red Beet powder. These complete the product’s ingredient list but are not active constituents.
EVP 3D Raspberry Lemonade by Evogen Drug Interactions
HelloPharmacist Interaction Report
EVP 3D Raspberry Lemonade by Evogen interacts with medications through its L-tyrosine, L-citrulline, sodium (listed twice), and lion's mane extract.
The most serious interaction is L-tyrosine with levodopa (a Parkinson's medication), where tyrosine may reduce levodopa's effectiveness by competing for absorption — doses should be separated by at least 2 hours.
Read the full breakdown — every affected drug type, severity by severity
L-tyrosine also has a moderate interaction with thyroid hormone medications, as it's a precursor to thyroid hormones and might increase their levels. L-citrulline moderately interacts with blood pressure drugs (antihypertensives) and erectile dysfunction medications (phosphodiesterase-5 inhibitors like sildenafil), both through additive blood vessel relaxation that could lower blood pressure further.
Sodium appears twice in this product and has moderate interactions with blood pressure medications, corticosteroids (which retain sodium), lithium (a mood stabilizer where sodium changes alter drug levels), HIV medications (didanosine), certain bowel-prep drugs (sodium phosphates), vasopressin inhibitors (tolvaptan), and other sodium-containing drugs — all carrying a risk of high sodium levels in the blood (hypernatremia). Lion's mane extract moderately interacts with blood thinners and antiplatelet drugs (raising bleeding risk), antidiabetes drugs (additive glucose-lowering), and immunosuppressants (potentially interfering with immune control).
Coconut water powder has a minor interaction with antidiabetes drugs, theoretically increasing low blood sugar risk. We could not check arginine nitrate for interactions.
Altogether, these interactions span 753 individual medications.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against EVP 3D Raspberry Lemonade?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in EVP 3D Raspberry Lemonade interact with 753 drugs. Click any drug to see the details.
6 of the 10 ingredients in EVP 3D Raspberry Lemonade interact with drugs. Each result below shows which ingredient is responsible. Lion's Mane extract Dimethylaminoethanol Sodium L-Citrulline Coconut Water powder L-Tyrosine
DiltiazemAdizem-SR, Adizem-XL, Angitil SR, Angitil XL, Calcicard CR, Cardizem +23 more
How Diltiazem interacts with EVP 3D Raspberry Lemonade — through 2 ingredients. Tap an ingredient for the detail:
L-citrullineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline + Diltiazem interactionSodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Diltiazem interactionDiltiazem, EnalaprilTeczem
How Diltiazem, Enalapril interacts with EVP 3D Raspberry Lemonade — through 2 ingredients. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Diltiazem, Enalapril interactionL-citrullineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline + Diltiazem, Enalapril interactionDiphenhydramine Hydrochloride, Naproxen SodiumAleve PM
How Diphenhydramine Hydrochloride, Naproxen Sodium interacts with EVP 3D Raspberry Lemonade — through 2 ingredients. Tap an ingredient for the detail:
Lion's Mane ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
Read the full Lion's Mane Extract + Diphenhydramine Hydrochloride, Naproxen Sodium interactionDimethylaminoethanolAnticholinergic Drugs Minor
Interaction Summary
Theoretically, deanol might decrease the effectiveness of anticholinergic drugs.
Read the full Dimethylaminoethanol + Diphenhydramine Hydrochloride, Naproxen Sodium interactionDipyridamoleDipyridamole, Persantin, Persantin Injection, Persantin Retard, Persantine
How Dipyridamole interacts with EVP 3D Raspberry Lemonade — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
Read the full Lion's Mane Extract + Dipyridamole interactionDiroximel FumarateVumerity
How Diroximel Fumarate interacts with EVP 3D Raspberry Lemonade — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
Read the full Lion's Mane Extract + Diroximel Fumarate interactionDoxazosin MesylateCardura
How Doxazosin Mesylate interacts with EVP 3D Raspberry Lemonade — through 2 ingredients. Tap an ingredient for the detail:
L-citrullineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline + Doxazosin Mesylate interactionSodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Doxazosin Mesylate interactionDulaglutideTrulicity
How Dulaglutide interacts with EVP 3D Raspberry Lemonade — through 2 ingredients. Tap an ingredient for the detail:
Lion's Mane ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, lion's mane mushroom may have additive effects when used with antidiabetes drugs.
Read the full Lion's Mane Extract + Dulaglutide interactionCoconut Water PowderAntidiabetes Drugs Minor
Interaction Summary
Theoretically, taking coconut with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Coconut Water Powder + Dulaglutide interactionDurvalumabImfinzi
How Durvalumab interacts with EVP 3D Raspberry Lemonade — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
Read the full Lion's Mane Extract + Durvalumab interactionEculizumabSoliris
How Eculizumab interacts with EVP 3D Raspberry Lemonade — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
Read the full Lion's Mane Extract + Eculizumab interactionEdoxabanSavaysa
How Edoxaban interacts with EVP 3D Raspberry Lemonade — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
Read the full Lion's Mane Extract + Edoxaban interactionEfalizumabRaptiva
How Efalizumab interacts with EVP 3D Raspberry Lemonade — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
Read the full Lion's Mane Extract + Efalizumab interactionEffientPrasugrel
How Effient interacts with EVP 3D Raspberry Lemonade — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
Read the full Lion's Mane Extract + Effient interactionEfgartigimod Alfa-fcabVyvgart
How Efgartigimod Alfa-fcab interacts with EVP 3D Raspberry Lemonade — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
Read the full Lion's Mane Extract + Efgartigimod Alfa-fcab interactionElranatamabElrexfio
How Elranatamab interacts with EVP 3D Raspberry Lemonade — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
Read the full Lion's Mane Extract + Elranatamab interactionEmapalumab-lzsgGamifant
How Emapalumab-lzsg interacts with EVP 3D Raspberry Lemonade — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
Read the full Lion's Mane Extract + Emapalumab-lzsg interactionEmpagliflozinJardiance
How Empagliflozin interacts with EVP 3D Raspberry Lemonade — through 2 ingredients. Tap an ingredient for the detail:
Lion's Mane ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, lion's mane mushroom may have additive effects when used with antidiabetes drugs.
Read the full Lion's Mane Extract + Empagliflozin interactionCoconut Water PowderAntidiabetes Drugs Minor
Interaction Summary
Theoretically, taking coconut with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Coconut Water Powder + Empagliflozin interactionEmpagliflozin, Linagliptin, Metformin HydrochlorideTrijardy XR
How Empagliflozin, Linagliptin, Metformin Hydrochloride interacts with EVP 3D Raspberry Lemonade — through 2 ingredients. Tap an ingredient for the detail:
Lion's Mane ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, lion's mane mushroom may have additive effects when used with antidiabetes drugs.
Read the full Lion's Mane Extract + Empagliflozin, Linagliptin, Metformin Hydrochloride interactionCoconut Water PowderAntidiabetes Drugs Minor
Interaction Summary
Theoretically, taking coconut with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Coconut Water Powder + Empagliflozin, Linagliptin, Metformin Hydrochloride interactionEmpagliflozin, MetforminSynjardy
How Empagliflozin, Metformin interacts with EVP 3D Raspberry Lemonade — through 2 ingredients. Tap an ingredient for the detail:
Lion's Mane ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, lion's mane mushroom may have additive effects when used with antidiabetes drugs.
Read the full Lion's Mane Extract + Empagliflozin, Metformin interactionCoconut Water PowderAntidiabetes Drugs Minor
Interaction Summary
Theoretically, taking coconut with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Coconut Water Powder + Empagliflozin, Metformin interactionEmpagliflozin, Metformin HydrochlorideSynjardy XR
How Empagliflozin, Metformin Hydrochloride interacts with EVP 3D Raspberry Lemonade — through 2 ingredients. Tap an ingredient for the detail:
Lion's Mane ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, lion's mane mushroom may have additive effects when used with antidiabetes drugs.
Read the full Lion's Mane Extract + Empagliflozin, Metformin Hydrochloride interactionCoconut Water PowderAntidiabetes Drugs Minor
Interaction Summary
Theoretically, taking coconut with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Coconut Water Powder + Empagliflozin, Metformin Hydrochloride interactionEnalapril MaleateEpaned, Vasotec
How Enalapril Maleate interacts with EVP 3D Raspberry Lemonade — through 2 ingredients. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Enalapril Maleate interactionL-citrullineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline + Enalapril Maleate interactionEnalapril Maleate, FelodipineLexxel
How Enalapril Maleate, Felodipine interacts with EVP 3D Raspberry Lemonade — through 2 ingredients. Tap an ingredient for the detail:
L-citrullineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline + Enalapril Maleate, Felodipine interactionSodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Enalapril Maleate, Felodipine interactionEnalapril Maleate, HydrochlorothiazideVaseretic
How Enalapril Maleate, Hydrochlorothiazide interacts with EVP 3D Raspberry Lemonade — through 2 ingredients. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Enalapril Maleate, Hydrochlorothiazide interactionL-citrullineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline + Enalapril Maleate, Hydrochlorothiazide interactionEnoxaparinLovenox
How Enoxaparin interacts with EVP 3D Raspberry Lemonade — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
Read the full Lion's Mane Extract + Enoxaparin interactionEpcoritamab-byspEpkinly
How Epcoritamab-bysp interacts with EVP 3D Raspberry Lemonade — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
Read the full Lion's Mane Extract + Epcoritamab-bysp interactionEplerenoneInspra
How Eplerenone interacts with EVP 3D Raspberry Lemonade — through 2 ingredients. Tap an ingredient for the detail:
L-citrullineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline + Eplerenone interactionSodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Eplerenone interactionEpoprostenolFlolan
How Epoprostenol interacts with EVP 3D Raspberry Lemonade — through 2 ingredients. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Epoprostenol interactionL-citrullineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline + Epoprostenol interactionEprosartanTeveten
How Eprosartan interacts with EVP 3D Raspberry Lemonade — through 2 ingredients. Tap an ingredient for the detail:
L-citrullineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline + Eprosartan interactionSodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Eprosartan interactionEptifibatideIntegrilin
How Eptifibatide interacts with EVP 3D Raspberry Lemonade — through 1 ingredient. Tap an ingredient for the detail:
Lion's Mane ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
Read the full Lion's Mane Extract + Eptifibatide interactionErtugliflozinSteglatro
How Ertugliflozin interacts with EVP 3D Raspberry Lemonade — through 2 ingredients. Tap an ingredient for the detail:
Lion's Mane ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, lion's mane mushroom may have additive effects when used with antidiabetes drugs.
Read the full Lion's Mane Extract + Ertugliflozin interactionCoconut Water PowderAntidiabetes Drugs Minor
Interaction Summary
Theoretically, taking coconut with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Coconut Water Powder + Ertugliflozin interactionErtugliflozin, Metformin HydrochlorideSegluromet
How Ertugliflozin, Metformin Hydrochloride interacts with EVP 3D Raspberry Lemonade — through 2 ingredients. Tap an ingredient for the detail:
Lion's Mane ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, lion's mane mushroom may have additive effects when used with antidiabetes drugs.
Read the full Lion's Mane Extract + Ertugliflozin, Metformin Hydrochloride interactionCoconut Water PowderAntidiabetes Drugs Minor
Interaction Summary
Theoretically, taking coconut with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Coconut Water Powder + Ertugliflozin, Metformin Hydrochloride interactionEach ingredient & the kinds of drugs it affects
For each ingredient in EVP 3D Raspberry Lemonade with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Lion's Mane extract
Anticoagulant/Antiplatelet Drugs
Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
In vitro research suggests that lion's mane mushroom extracts can inhibit platelet aggregation.
Antidiabetes Drugs
Theoretically, lion's mane mushroom may have additive effects when used with antidiabetes drugs.
Animal research suggests that an aqueous extract of lion's mane mushroom can reduce serum glucose and increase serum insulin.
Immunosuppressants
Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
In animal and in vitro research, lion's mane mushroom polysaccharides stimulate the immune system.
Dimethylaminoethanol
Anticholinergic Drugs
Theoretically, deanol might decrease the effectiveness of anticholinergic drugs.
Deanol is thought to increase acetylcholine levels.
Cholinergic Drugs
Theoretically, deanol might increase the effects and adverse effects of cholinergic drugs.
Deanol is thought to increase acetylcholine levels.
Sodium
Antihypertensive Drugs
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.
Corticosteroids
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.
Didanosine (Videx)
Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.
Lithium
Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.
Sodium Phosphates
Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.
Sodium-Containing Drugs
Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.
Tolvaptan (Samsca)
Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.
L-Citrulline
Antihypertensive Drugs
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
L-citrulline is converted to L-arginine, which can increase nitric oxide and cause vasodilation. However, a meta-analysis of 5 small clinical studies suggests that taking L-citrulline 3-6 grams daily for 1-8 weeks does not lower blood pressure when compared with control.
Phosphodiesterase-5 Inhibitors
Theoretically, concurrent use of phosphodiesterase-5 (PDE-5) inhibitors and L-citrulline might result in additive vasodilation.
L-citrulline is converted to L-arginine, which can increase nitric oxide and cause vasodilation. Theoretically, taking L-arginine with PDE-5 inhibitors might have additive vasodilatory and hypotensive effects. However, in studies evaluating the combined use of L-arginine and sildenafil for erectile dysfunction, hypotension was not reported.
Coconut Water powder
Antidiabetes Drugs
Theoretically, taking coconut with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that coconut milk might increase insulin levels and/or decrease blood glucose levels.
L-Tyrosine
Levodopa
Theoretically, tyrosine might decrease the effectiveness of levodopa.
Tyrosine and levodopa compete for absorption in the proximal duodenum by the large neutral amino acid (LNAA) transport system. Advise patients to separate doses of tyrosine and levodopa by at least 2 hours.
Thyroid Hormone
Theoretically, tyrosine might have additive effects with thyroid hormone medications.
Tyrosine is a precursor to thyroxine and might increase levels of thyroid hormones.
Brand information
Manufacturer and brand details for EVP 3D Raspberry Lemonade, from the product label.
Evogen
See all Evogen products- Name
- Evogen Nutrition
- Street Address
- 271 E. Hacienda Ave.
- City
- Campbell
- State
- CA
- ZipCode
- 95008
- Phone Number
- 1.408.364.1650
- Web Address
- www.EvogenNutrition.com
EVP 3D Raspberry Lemonade by Evogen: Common Questions
Does EVP 3D Raspberry Lemonade by Evogen interact with any medications?
How can one product interact with so many drugs?
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if EVP 3D Raspberry Lemonade is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind EVP 3D Raspberry Lemonade’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sodium
Interacts with 205 drugsSodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...
Read the full Sodium monograph → Herb & supplement monographBeta-alanine
Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-intensity exercise. The evidence is moderat...
Read the full Beta-alanine monograph → Herb & supplement monographL-citrulline
Interacts with 178 drugsL-citrulline is an amino acid that the body turns into L-arginine to help make nitric oxide, which relaxes blood vessels and may improve blood flow. It is popular for exercise performance an...
Read the full L-citrulline monograph → Herb & supplement monographCoconut
Interacts with 86 drugsCoconut is a nutritious tropical food enjoyed as oil, water, milk, and flesh, and it is generally safe to eat in normal food amounts. While some uses (like skin moisturizing and hydration) h...
Read the full Coconut monograph → Herb & supplement monographCreatine
Creatine is one of the most studied sports supplements, with solid evidence that it can boost strength and performance during short, high-intensity activities like weightlifting and sprintin...
Read the full Creatine monograph → Herb & supplement monographTyrosine
Interacts with 21 drugsL-tyrosine is an amino acid your body uses to make brain chemicals like dopamine and norepinephrine. Some studies suggest it may help mental performance during short-term stress, sleep loss,...
Read the full Tyrosine monograph → Herb & supplement monographDeanol
Interacts with 219 drugsDeanol (DMAE) is a compound related to choline that is marketed for memory, focus, and mood, but solid human evidence for most of these uses is limited or mixed. It can cause side effects in...
Read the full Deanol monograph → Herb & supplement monographLion's Mane Mushroom
Interacts with 327 drugsLion's mane is an edible mushroom that is popular as a 'nootropic' for memory, focus, and nerve health, but solid human evidence is still limited and early. It is generally well tolerated as...
Read the full Lion's Mane Mushroom monograph →Sources & How We Checked
EVP 3D Raspberry Lemonade's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 180 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Coconut 10 references
- Teuber SS, Peterson WR. Systemic allergic reaction to coconut (Cocos nucifera) in 2 subjects with hypersensitivity to tree nut and demonstration of cross-reactivity to legumin-like seed storage proteins: new coconut and walnut food allergens. J Allergy Cl PubMed
- Rosado A, Fernandez-Rivas M, Gonzalez-Mancebo E, et al. Anaphylaxis to coconut. Allergy 2002;57(2):182-3. PubMed
- Karmakar PR, Das A, Chatterjee BP. Placebo-controlled immunotherapy with Cocos nucifera pollen extract. Int Arch Allergy Immunol 1994;103(2):194-201. PubMed
- Anagnostou K. Coconut Allergy Revisited. Children (Basel). 2017;4(10). pii: E85. PubMed
- Cifuentes L, Mistrello G, Amato S, et al. Identification of cross-reactivity between buckwheat and coconut. Ann Allergy Asthma Immunol. 2015;115(6):530-2. PubMed
- Michavila Gomez A, Amat Bou M, Gonzalez Cortés MV, Segura Navas L, Moreno Palanques MA, Bartolomé B. Coconut anaphylaxis: Case report and review. Allergol Immunopathol (Madr). 2015;43(2):219-20. PubMed
- 21CFR170.3. U.S. Food and Drug Administration Department of Health and Human Services. Updated April 1, 2017. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=170.3
- Alatawi KA, Alshubaily FA. Coconut products alleviate hyperglycaemic, hyperlipidimic and nephropathy indices in streptozotocin-induced diabetic wistar rats. Saudi J Biol Sci. 2021;28(8):4224-4231. PubMed
- Kruse L, Lor J, Yousif R, Pongracic JA, Fishbein AB. Coconut allergy: Characteristics of reactions and diagnostic predictors in a pediatric tertiary care center. Ann Allergy Asthma Immunol 2021;126(5):562-568.
- Pathmanandavel K, Kaur N, Joshi P, Ford LS. Anaphylaxis and allergy to coconut: An Australian pediatric case series. J Allergy Clin Immunol Pract 2020;8(10):3657-3659. PubMed
Tyrosine 4 references
- Meyer JS, Welch KM, Deshmukh VD, et al. Neurotransmitter precursor amino acids in the treatment of multi-infarct dementia and Alzheimer's disease. J Amer Geriat Soc 1977;25:289-98.
- DiPiro JT, Talbert RL, Yee GC, et al; eds. Pharmacotherapy: A pathophysiologic approach. 4th ed. Stamford, CT: Appleton & Lange, 1999.
- Wood DR, Reimherr FW, Wender PH. Amino acid precursors for the treatment of attention deficit disorder, residual type. Psychopharmacol Bull 1985;21:146-9.
- van Spronsen FJ, van Rijn M, Bekhof J. Phenylketonuria: tyrosine supplementation in phenylalanine-restricted diets. Am J Clin Nutr 2001;73:153-7. PubMed
Creatine 86 references
- Koshy KM, Griswold E, Schneeberger EE. Interstitial nephritis in a patient taking creatine. N Engl J Med 1999;340:814-5. PubMed
- Vahedi K, Domingo V, Amarenco P, Bousser MG. Ischemic stroke in a sportsman who consumed MaHuang extract and creatine monohydrate for bodybuilding. J Neurol Neurosurg Psychiatr 2000;68:112-3.
- Greenhaff P. Renal dysfunction accompanying oral creatine supplements. Lancet 1998;352:233-4. PubMed
- Vandenberghe K, Goris M, Van Hecke P, et al. Long-term creatine intake is beneficial to muscle performance during resistance training (abstract). J Appl Physiol 1997;83:2055-63. PubMed
- Hultman E, Soderlund K, Timmons JA, et al. Muscle creatine loading in men. J Appl Physiol 1996;81:232-7. PubMed
- Pritchard NR, Kalra PA. Renal dysfunction accompanying oral creatine supplements. Lancet 1998;351:1252-3. PubMed
- Poortmans JR, Auquier H, Renaut V, et al. Effect of short-term creatine supplementation on renal responses in men (abstract). Eur J Appl Physiol Occup Physiol 1997;76:566-7. PubMed
- Poortmans JR, Francaux M. Long-term oral creatine supplementation does not impair renal function in healthy athletes. Med Sci Sports Exerc 1999;31:1108-10. PubMed
- Mihic S, MacDonald JR, McKenzie S, Tarnopolsky MA. Acute creatine loading increases fat-free mass, but does not affect blood pressure, plasma creatinine, or CK activity in men and women. Med Sci Sports Exerc 2000;32:291-6. PubMed
- Rawson ES, Wehnert ML, Clarkson PM. Effects of 30 days of creatine ingestion in older men. Eur J Appl Physiol Occup Physiol 1999;80:139-44. PubMed
- Earnest CP, Almada AL, Mitchell TL. High-performance capillary electrophoresis-pure creatine monohydrate reduces blood lipids in men and women. Clin Sci (Colch) 1996;91:113-8. PubMed
- Juhn MS. Oral creatine supplementation. Separating fact from hype. Phys Sportsmed 1999;27:47-50,53-54,56,61,89. PubMed
- Juhn MS, O'Kane JW, Vinci DM. Oral creatine supplementation in male collegiate athletes: a survey of dosing habits and side effects. J Am Diet Assoc 1999;99:593-5.
- Green AL, Hultman E, Macdonald IA, et al. Carbohydrate ingestion augments skeletal muscle creatine accumulation during creatine supplementation in humans. Am J Physiol 1996;271:E821-6. PubMed
- Balsom PD, Soderlund K, Sjodin B, Ekblom B. Skeletal muscle metabolism during short duration high-intensity exercise: influence of creatine supplementation. Acta Physiol Scand 1995;154:303-10. PubMed
- Snow RJ, McKenna MJ, Selig SE, et al. Effect of creatine supplementation on sprint exercise performance and muscle metabolism. (abstract) J Appl Physiol 1998;84:1667-73. PubMed
- McNaughton LR, Dalton B, Tarr J. The effects of creatine supplementation on high-intensity exercise performance in elite performers. (abstract) Eur J Appl Physiol Occup Physiol 1998;78:236-40. PubMed
- Groeneveld GJ, Veldink JH, van der Tweel I, et al. A randomized sequential trial of creatine in amyotrophic lateral sclerosis. Ann Neurol 2003;53:437-45. . PubMed
- Robinson SJ. Acute quadriceps compartment syndrome and rhabdomyolysis in a weight lifter using high-dose creatine supplementation. J Am Board Fam Pract 2000;13:134-7. PubMed
- Kammer RT. Lone atrial fibrillation associated with creatine monohydrate supplementation. Pharmacotherapy 2005;25:762-4. PubMed
- Gualano B, Ugrinowitsch C, Novaes RB, et al. Effects of creatine supplementation on renal function: a randomized, double-blind, placebo-controlled clinical trial. Eur J Appl Physiol 2008;103:33-40. PubMed
- Pfeffer, G., Majamaa, K., Turnbull, D. M., Thorburn, D., and Chinnery, P. F. Treatment for mitochondrial disorders. Cochrane Database.Syst.Rev. 2012;4:CD004426. PubMed
- Boos, C. J., White, S. H., Bland, S. A., and McAllister, P. D. Dietary supplements and military operations: caution is advised. J R.Army Med Corps 2010;156(1):41-43. PubMed
- Kreider, R. B. Dietary supplements and the promotion of muscle growth with resistance exercise. Sports Med 1999;27(2):97-110. PubMed
- Juhn, M. S., O'Kane, J. W., and Vinci, D. M. Oral creatine supplementation in male collegiate athletes: a survey of dosing habits and side effects. J Am.Diet.Assoc 1999;99(5):593-595.
- Volek, J. S., Duncan, N. D., Mazzetti, S. A., Putukian, M., Gomez, A. L., and Kraemer, W. J. No effect of heavy resistance training and creatine supplementation on blood lipids. Int J Sport Nutr.Exerc.Metab 2000;10(2):144-156. PubMed
- Robinson, T. M., Sewell, D. A., Casey, A., Steenge, G., and Greenhaff, P. L. Dietary creatine supplementation does not affect some haematological indices, or indices of muscle damage and hepatic and renal function. Br.J Sports Med 2000;34(4):284-288. PubMed
- Tarnopolsky, M. A. Potential benefits of creatine monohydrate supplementation in the elderly. Curr.Opin.Clin Nutr.Metab Care 2000;3(6):497-502. PubMed
- Tarnopolsky, M. A. and MacLennan, D. P. Creatine monohydrate supplementation enhances high-intensity exercise performance in males and females. Int J Sport Nutr.Exerc.Metab 2000;10(4):452-463. PubMed
- Arciero, P. J., Hannibal, N. S., III, Nindl, B. C., Gentile, C. L., Hamed, J., and Vukovich, M. D. Comparison of creatine ingestion and resistance training on energy expenditure and limb blood flow. Metabolism 2001;50(12):1429-1434. PubMed
- Chrusch, M. J., Chilibeck, P. D., Chad, K. E., Davison, K. S., and Burke, D. G. Creatine supplementation combined with resistance training in older men. Med Sci.Sports Exerc. 2001;33(12):2111-2117. PubMed
- Cox, G., Mujika, I., Tumilty, D., and Burke, L. Acute creatine supplementation and performance during a field test simulating match play in elite female soccer players. Int J Sport Nutr.Exerc.Metab 2002;12(1):33-46. PubMed
- Kilduff, L. P., Vidakovic, P., Cooney, G., Twycross-Lewis, R., Amuna, P., Parker, M., Paul, L., and Pitsiladis, Y. P. Effects of creatine on isometric bench-press performance in resistance-trained humans. Med Sci.Sports Exerc. 2002;34(7):1176-1183. PubMed
- Brose, A., Parise, G., and Tarnopolsky, M. A. Creatine supplementation enhances isometric strength and body composition improvements following strength exercise training in older adults. J Gerontol A Biol.Sci.Med Sci. 2003;58(1):11-19. PubMed
- Volek, J. S., Ratamess, N. A., Rubin, M. R., Gomez, A. L., French, D. N., McGuigan, M. M., Scheett, T. P., Sharman, M. J., Hakkinen, K., and Kraemer, W. J. The effects of creatine supplementation on muscular performance and body composition responses to
- Tyler, T. F., Nicholas, S. J., Hershman, E. B., Glace, B. W., Mullaney, M. J., and McHugh, M. P. The effect of creatine supplementation on strength recovery after anterior cruciate ligament (ACL) reconstruction: a randomized, placebo-controlled, double-b DOI
- Groeneveld, G. J., Beijer, C., Veldink, J. H., Kalmijn, S., Wokke, J. H., and van den Berg, L. H. Few adverse effects of long-term creatine supplementation in a placebo-controlled trial. Int J Sports Med 2005;26(4):307-313. PubMed
- Astorino, T. A., Marrocco, A. C., Gross, S. M., Johnson, D. L., Brazil, C. M., Icenhower, M. E., and Kneessi, R. J. Is running performance enhanced with creatine serum ingestion? J Strength.Cond.Res 2005;19(4):730-734. PubMed
- Cramer, J. T., Stout, J. R., Culbertson, J. Y., and Egan, A. D. Effects of creatine supplementation and three days of resistance training on muscle strength, power output, and neuromuscular function. J Strength.Cond.Res 2007;21(3):668-677. PubMed
- Young, P., De, Jonghe P., Stogbauer, F., and Butterfass-Bahloul, T. Treatment for Charcot-Marie-Tooth disease. Cochrane.Database.Syst.Rev. 2008;(1):CD006052. PubMed
- Ostojic, S. M. and Ahmetovic, Z. Gastrointestinal distress after creatine supplementation in athletes: are side effects dose dependent? Res.Sports Med. 2008;16(1):15-22. PubMed
- Whitt, K. N., Ward, S. C., Deniz, K., Liu, L., Odin, J. A., and Qin, L. Cholestatic liver injury associated with whey protein and creatine supplements. Semin.Liver Dis. 2008;28(2):226-231. PubMed
- Koenig CA, Benardot D Cody M Thompson WR. Comparison of creatine monohydrate and carbohydrate supplementation on repeated jump height performance. J Strength Cond Res. 2008;22(4):1081-1086. PubMed
- Gordon, P. H., Cheung, Y. K., Levin, B., Andrews, H., Doorish, C., Macarthur, R. B., Montes, J., Bednarz, K., Florence, J., Rowin, J., Boylan, K., Mozaffar, T., Tandan, R., Mitsumoto, H., Kelvin, E. A., Chapin, J., Bedlack, R., Rivner, M., McCluskey, L.
- Bender, A., Samtleben, W., Elstner, M., and Klopstock, T. Long-term creatine supplementation is safe in aged patients with Parkinson disease. Nutr.Res. 2008;28(3):172-178. PubMed
- Parness, J. You're "hot" from pumping iron? Anesth.Analg. 2009;108(3):711-713. PubMed
- Gualano, B., Ferreira, D. C., Sapienza, M. T., Seguro, A. C., and Lancha, A. H., Jr. Effect of short-term high-dose creatine supplementation on measured GFR in a young man with a single kidney. Am.J.Kidney Dis. 2010;55(3):e7-e9. PubMed
- Saidi, H. and Mani, M. Severe metabolic acidosis secondary to coadministration of creatine and metformin, a case report. Am.J.Emerg.Med. 2010;28(3):388-6. PubMed
- Gualano, B., de, Salles Painelli, V, Roschel, H., Lugaresi, R., Dorea, E., Artioli, G. G., Lima, F. R., da Silva, M. E., Cunha, M. R., Seguro, A. C., Shimizu, M. H., Otaduy, M. C., Sapienza, M. T., da Costa, Leite C., Bonfa, E., and Lancha Junior, A. H.
- Neves, M., Jr., Gualano, B., Roschel, H., Lima, F. R., Lucia, de Sa-Pinto, Seguro, A. C., Shimizu, M. H., Sapienza, M. T., Fuller, R., Lancha, A. H., Jr., and Bonfa, E. Effect of creatine supplementation on measured glomerular filtration rate in postmeno
- Gufford, B. T., Sriraghavan, K., Miller, N. J., Miller, D. W., Gu, X., Vennerstrom, J. L., and Robinson, D. H. Physicochemical characterization of creatine N-methylguanidinium salts. J.Diet.Suppl 2010;7(3):240-252.
- Lugaresi, R., Leme, M., de, Salles Painelli, V, Murai, I. H., Roschel, H., Sapienza, M. T., Lancha Junior, A. H., and Gualano, B. Does long-term creatine supplementation impair kidney function in resistance-trained individuals consuming a high-protein di
- Poortmans, J. R. and Francaux, M. Renal dysfunction accompanying oral creatine supplements. Lancet 7-18-1998;352(9123):234. PubMed
- Maganaris, C. N. and Maughan, R. J. Creatine supplementation enhances maximum voluntary isometric force and endurance capacity in resistance trained men. Acta Physiol Scand. 1998;163(3):279-287. PubMed
- Vandebuerie, F., Vanden Eynde, B., Vandenberghe, K., and Hespel, P. Effect of creatine loading on endurance capacity and sprint power in cyclists. Int J Sports Med 1998;19(7):490-495. PubMed
- Juhn, M. S. and Tarnopolsky, M. Oral creatine supplementation and athletic performance: a critical review. Clin J Sport Med 1998;8(4):286-297. PubMed
- Vandenberghe K, Van Hecke P, Van Leemputte M, and et al. Inhibition of muscle phosphocreatine resynthesis by caffeine after creatine loading. Med Sci Sports Exerc 1997;29(5 Supplement):249.
- Ziegenfuss T, Lowery LM, and Lemon PW. Acute fluid volume changes in men during three days of creatine supplementation. J Exerc Physiol Online 1998;1(3): .
- Kuehl K, Goldberg L, and Elliot D. Renal insufficiency after creatine supplementation in a college football athlete. Med Sci Sports Exerc 1998;30(5 Suppl ):S235. DOI
- Balsom PD, Ekblom B, Soderlund K, and et al. Creatine supplementation and dynamic high-intensity intermittent excercise. Scand J Med Sci Sports 1993;3:143-149.
- Kirksey KB, Warren BJ, Stone MH, and et al. The effects of six weeks of creatine monohydrate supplementation in male and female track athletes. Med Sci Sports Exerc 1997;29(5 Suppl):S145.
- Kreider R, Ransom J, Rasmussen C, and et al. Creatine supplementation during pre-season football does not affect markers of renal function. 83rd Annual Experimental Biology Meeting 1999;
- Rasmussen C, Kreider R, Ransom J, and et al. Creatine supplementation during pre-season football training does not affect fluid or electrolyte status. 46th Annual American College of Sports Medicine Annual Meeting 1999; DOI
- Tan CW, Hae Tha M, Joo Ng H. Creatine supplementation and venous thrombotic events. Am J Med 2014;127(8):e7-8. PubMed
- Young C, Oladipo O, Frasier S, et al. Hemorrhagic stroke in young healthy male following use of sports supplement Jack3d. Mil Med 2012;177(12):1450-4. PubMed
- Vilella AL, Limsuwat C, Williams DR, Seifert CF. Cholestatic jaundice as a result of combination designer supplement ingestion. Ann Pharmacother 2013;47(7-8):e33. PubMed
- Li N, Hauser R, Holford T, et al. Muscle-building supplement use and increased risk of testicular germ cell cancer in men from Connecticut and Massachusetts. Br J Cancer 2015;112(7):1247-50. PubMed
- Centers for Disease Control and Prevention (CDC). Hyperthermia and dehydration-related deaths associated with rapid weight loss in three collegiate wrestlers - North Carolina, Wisconsin, and Michigan, November-December 1997. MMWR Morb Mortal Wkly Rep 1998
- Litsky F. Collegiate wrestling deaths raise fears about training. The New York Times. December 19, 1997. Available at: http://www.nytimes.com/1997/12/19/sports/wrestling-collegiate-wrestling-deaths-raise-fears-about-training.html.
- The Associated Press. Creatine ruled out in athletes' deaths. The New York Times. May 2, 1998. Available at: http://www.nytimes.com/1998/05/02/sports/plus-college-wrestling-creatine-ruled-out-in-athletes-deaths.html.
- Creatine in the dock. Men's Fitness Magazine (Australia). September 2013. Available at: http://www.mensfitnessmagazine.com.au/2013/09/creatine-in-the-dock/.
- Galvan E, Walker Dk, Simbo SY, et al. Acute and chronic safety and efficacy of dose dependent creatine nitrate supplementation and exercise performance. J Int Soc Sports Nutr. 2016 Mar 31;13:12. PubMed
- Deminice R, Rosa FT, Pfrimer K, Ferrioli E, Jorao AA, Freitas E. Creatine supplementation increases total body water in soccer players: a deuterium oxide dilution study. Int J Sports Med. 2016 Feb;37(2):149-53. PubMed
- Wilkinson TJ, Lemmy AB, Jones AG, et al. Can creatine supplementation improve body composition and objective physical function in Rheumatoid Arthritis patients? A randomized controlled trial. Arthritis Care Res (Hoboken). 2016 Jun;68(6):729-37. PubMed
- Kreider RB, Kalman DS, Antonio J, et al. International Society of Sports Nutrition position stand: safety and efficacy of creating supplementation in exercise, sport, and medicine. J Int Soc Sports Nutr. 2017;14:18.
- de Guingand DL, Palmer KR, Snow RJ, Davies-Tuck ML, Ellery SJ. Risk of adverse outcomes in females taking oral creatine monohydrate: a systematic review and meta-analysis. Nutrients. 2020;12(6):E1780. PubMed
- Almeida D, Colombini A, Machado M. Creatine supplementation improves performance, but is it safe? Double-blind placebo-controlled study. J Sports Med Phys Fitness. 2020;60(7):1034-9. PubMed
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- Whinton AK, Donahoe K, Gao R, et al. Repeated application of a novel creatine cream improves muscular peak and average power in male subjects. J Strength Cond Res. 2020;34(9):2482-2491. PubMed
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- Chilibeck PD, Candow DG, Landeryou T, Kaviani M, Paus-Jenssen L. Effects of creatine and resistance training on bone health in postmenopausal women. Med Sci Sports Exerc. 2015;47(8):1587-95. PubMed
- Forbes SC, Candow DG, Ostojic SM, Roberts MD, Chilibeck PD. Meta-analysis examining the importance of creatine ingestion strategies on lean tissue mass and strength in older adults. Nutrients 2021;13(6):1912. PubMed
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- Todorovic N, Korovljev D, Stajer V, Jorga J, Ostojic SM. Creatine consumption and liver disease manifestations in individuals aged 12?years and over. Food Sci Nutr 2022;11(2):1134-1141. PubMed
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Deanol 15 references
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Lion's Mane Mushroom 6 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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