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Dietary supplement

Extra Strength Beta-Glucans with ImmunEnhancer Ingredients & Drug Interactions

by NOW

Extra Strength Beta-Glucans with ImmunEnhancer label
See full label image
Capsule Category: Fiber And Other Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Oct 7, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Extra Strength Beta-Glucans with ImmunEnhancer against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Extra Strength Beta-Glucans with ImmunEnhancer is a dietary supplement by NOW with 2 active ingredients. Its ingredients are commonly taken for immune support, cold and flu prevention, digestive and gut health.Based on those ingredients, 293 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Beta-1,3/1,6-D-Glucan Powder, ImmunEnhancer. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Extra Strength Beta-Glucans with ImmunEnhancer by NOW

Ask about any prescription or over-the-counter medication and we check it for interactions with Extra Strength Beta-Glucans with ImmunEnhancer by NOW — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Extra Strength Beta-Glucans with ImmunEnhancer by NOW

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 2 active ingredients. Larch arabinogalactan (listed as ImmunEnhancer) and beta-glucans (beta-1,3/1,6-D-glucan powder) are both soluble fibers thought to support immune function.

The capsule also holds inactive ingredients — hypromellose, cellulose, silicon dioxide, and magnesium stearate — which are standard binders and flow agents.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: healthy immune support and normal immune function.
  • We looked for evidence on: Common cold, Exercise-induced respiratory infections, Lower respiratory tract infections, Upper respiratory tract infection (URTI), Allergic rhinitis (hay fever), Otitis media — and 4 related terms.
  • The closest evidence on file: Larch Arabinogalactan is rated "Insufficient Reliable Evidence To Rate" for Common cold (Natural Medicines).
  • Also on file: Beta-glucans is rated "Insufficient Reliable Evidence To Rate" for Allergic rhinitis (hay fever), Lower respiratory tract infections, Exercise-induced respiratory infections, Otitis media, and more.

For larch arabinogalactan, the evidence we hold shows insufficient reliable data to rate its effect on common cold or cholesterol. For beta-glucans, the data suggests they're likely effective for lowering cholesterol and supporting heart health — that's the stronger evidence base here.

If you're taking this mainly for colds or general immunity, understand the research isn't settled on whether it helps.

The evidence, ingredient by ingredient Larch Arabinogalactan Beta-glucans

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beta-glucans from food are generally well tolerated, but concentrated supplement doses lack long-term safety data — use caution. Larch arabinogalactan is also generally well tolerated as a fiber, though some people experience bloating and gas.

One clinical trial of beta-glucans in children found one case of mild, temporary liver enzyme elevation. For pregnancy and lactation, safety data are too limited — talk with your doctor or pharmacist before taking it if you're pregnant, breastfeeding, or planning to.

Side effects, ingredient by ingredient Larch Arabinogalactan Beta-glucans

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Larch Arabinogalactan, Beta-glucans.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 293 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before starting, double-check if you take immunosuppressant drugs (used after transplant or for severe autoimmune disease) — this product may interfere with them (Moderate risk). Also flag any blood pressure medications; beta-glucans may lower blood pressure further.

Use the medication checker below with your exact prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product may help with cholesterol and heart health, but it's not proven for colds. The key concern is immunosuppressant and blood pressure medications — if you take either, check with your pharmacist first.

Bloating or gas is possible. It's generally well tolerated otherwise, but long-term safety data on the supplement dose are thin.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Extra Strength Beta-Glucans with ImmunEnhancer, straight from the product label.

Brand NOW
Barcode (UPC) 733739030337
Net contents 60 Veg Capsule(s)
Market status On market
Date entered into DSLD Mar 25, 2021
DSLD ID 245687
Product type Fiber And Other Nutrients
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Extra Strength Beta-Glucans with ImmunEnhancer by NOW, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Veg Capsule(s)
Maximum serving Sizes:
2 Veg Capsule(s)
Servings per container
30
UPC/BARCODE
733739030337
IngredientAmount% DV
ImmunEnhancer400 mg--
Beta-1,3/1,6-D-Glucan Powder500 mg--

Other ingredients: Hypromellose, Cellulose, Silicon Dioxide, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Usage: Take 2 capsules 1 to 3 times daily.

Formula

Beta-1,3/1,6-D-Glucan (Beta-Glucans) is a bioactive carbohydrate derived from the cell wall of Saccharomyces cerevisiae, commonly known as Bakers' yeast. Scientific studies have shown that Beta-1,3/1,6-D-Glucan supports a healthy immune system through its ability to maintain several aspects of the body’s normal immune functions. NOW Extra Strength Beta-Glucans is completed with ImmunEnhancer, a high molecular weight polysaccharide extracted from the larch tree that has been studied for its ability to promote a healthy immune response.

250 mg of Beta-Glucans with Larch Arabinogalactan

Triangle K (Kosher)

NOW Extra Strength Beta-Glucans has over twice the Beta-Glucans (250 mg per capsule) as in our regular strength product (100 mg per capsule).

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Caution: For adults only.

Consult physician if pregnant/nursing, taking medication, or have a medical condition.

Keep out of reach of children.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Formulation

Natural color variation may occur in this product.

Healthy Immune Support Supports Normal Immune Function

Vegetarian/Vegan

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients.

FDA Statement of Identity

A Dietary Supplement

Seals/Symbols

Triangle K (Kosher)

GMP Quality Assured

General Statements

General Health Family owned since 1968.

Brand IP Statement(s)

ImmunEnhancer is a Lonza trademark.

Storage

Store in a cool, dry place after opening.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Extra Strength Beta-Glucans with ImmunEnhancer by NOW label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Extra Strength Beta-Glucans with ImmunEnhancer label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Extra Strength Beta-Glucans with ImmunEnhancer by NOW

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Veg Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

ImmunEnhancer

Interacts with
121 drugs
400 mg per serving Form: Arabinogalactan

Larch arabinogalactan is a soluble fiber from larch trees that is mainly used as a prebiotic and for immune support. Early research is interesting but...

ImmunEnhancer monograph & interactions

Beta-1,3/1,6-D-Glucan Powder

Interacts with
293 drugs
500 mg per serving Form: Saccharomyces cerevisiae

Beta-glucans are natural fibers found in oats, barley, mushrooms, and yeast. The strongest evidence supports the oat and barley types for modestly low...

Beta-1,3/1,6-D-Glucan Powder monograph & interactions

Other (inactive) ingredients: Hypromellose, Cellulose, Silicon Dioxide, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Extra Strength Beta-Glucans with ImmunEnhancer by NOW Drug Interactions

Want to check YOUR meds against Extra Strength Beta-Glucans with ImmunEnhancer?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
293Drugs
293 Moderate

Ingredients driving the most interactions

Beta-1,3/1,6-D-Glucan Powder 293
ImmunEnhancer 121

Individual Drug Interactions

The ingredients in Extra Strength Beta-Glucans with ImmunEnhancer interact with 293 drugs. Click any drug to see the details.

2 of the 2 ingredients in Extra Strength Beta-Glucans with ImmunEnhancer interact with drugs. Each result below shows which ingredient is responsible. Beta-1,3/1,6-D-Glucan Powder ImmunEnhancer

Each ingredient & the kinds of drugs it affects

For each ingredient in Extra Strength Beta-Glucans with ImmunEnhancer with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Beta-1,3/1,6-D-Glucan Powder2 drug types · 293 drugs

Antihypertensive Drugs

Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Clinical research shows that taking beta-glucans may reduce systolic and diastolic blood pressure in some hypertensive individuals.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Some clinical research shows that beta-glucans have immunostimulant effects.

Likelihood Possible Evidence D
Beta-1,3/1,6-D-Glucan Powder full monograph & interactions

ImmunEnhancer1 drug type · 121 drugs

Immunosuppressants

Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects. Immunosuppressant drugs include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), and other drugs.

Likelihood Possible Evidence D
ImmunEnhancer full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Extra Strength Beta-Glucans with ImmunEnhancer, from the product label.

NOW

See all NOW products
Name
NOW Foods
Street Address
395 S. Glen Ellyn Rd.
City
Bloomingdale
State
IL
ZipCode
60108
Web Address
nowfoods.com
Pharmacist Counseling Corner

Extra Strength Beta-Glucans with ImmunEnhancer by NOW: Common Questions

Does Extra Strength Beta-Glucans with ImmunEnhancer by NOW interact with any medications?
Yes. Based on its ingredients, Extra Strength Beta-Glucans with ImmunEnhancer has a known interaction with 293 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Extra Strength Beta-Glucans with ImmunEnhancer contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help me avoid getting a cold?
The evidence we have on larch arabinogalactan for colds is insufficient — we can't say whether it works. If cold prevention is your main goal, the research backing isn't there yet.
Is it safe if I'm pregnant or breastfeeding?
There isn't enough safety data to know either way. Talk with your doctor or pharmacist before taking it — they can weigh the risks and benefits for your situation.
What are the side effects?
Both ingredients are generally well tolerated. The main side effect is bloating and gas. One clinical trial found one case of temporary liver enzyme elevation, but that's rare.
Does beta-glucans really lower cholesterol?
Yes — the evidence suggests beta-glucans are likely effective for lowering cholesterol and supporting heart health. That's where the strongest research sits.
What's ImmunEnhancer?
That's larch arabinogalactan, a soluble fiber extracted from larch trees. It's thought to support immune function, though evidence for specific benefits like cold prevention is still unclear.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Extra Strength Beta-Glucans with ImmunEnhancer label
Go deeper

The Full Monographs Behind Extra Strength Beta-Glucans with ImmunEnhancer’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Larch Arabinogalactan

Interacts with 121 drugs

Larch arabinogalactan is a soluble fiber from larch trees that is mainly used as a prebiotic and for immune support. Early research is interesting but limited, and most claims are not yet fi...

Read the full Larch Arabinogalactan monograph → Herb & supplement monograph

Beta-glucans

Interacts with 293 drugs

Beta-glucans are natural fibers found in oats, barley, mushrooms, and yeast. The strongest evidence supports the oat and barley types for modestly lowering cholesterol and blood sugar, while...

Read the full Beta-glucans monograph →
Sources

Sources & How We Checked

Extra Strength Beta-Glucans with ImmunEnhancer's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 19 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Larch Arabinogalactan 8 references
  1. D'Adamo P. Larch arabinogalactan. J Naturopath Med 1996;6:33-7.
  2. Kelly GS. Larch arabinogalactan: Clinical relevance of a novel immune-enhancing polysaccharide. Alt Med Rev 1999;4:96-103.
  3. Marett R, Slavin JL. No long-term benefits of supplementation with arabinogalactan on serum lipids and glucose. J Am Diet Assoc 2004;104:636-9.
  4. Robinson RR, Feirtag J, Slavin JL. Effects of dietary arabinogalactan on gastrointestinal and blood parameters in healthy human subjects. J Am Coll Nutr 2001;20:279-85. PubMed
  5. Udani JK, Singh BB, Barrett ML, Singh VJ. Proprietary arabinogalactan extract increases antibody response to the pneumonia vaccine: a randomized, double-blind, placebo-controlled, pilot study in healthy volunteers. Nutr J 2010;9:32. PubMed
  6. Grube B, Stier H, Riede L, Gruenwald J. Tolerability of a proprietary larch arabinogalactan extract: a randomized, double-blind, placebo-controlled clinical trial in healthy subjects. Food Nutr Sci 2012;3:1533-8. DOI
  7. Dion C, Chappuis E, Ripoll C. Does larch arabinogalactan enhance immune function? A review of mechanistic and clinical trials. Nutr Metab (Lond) 2016;13:28. PubMed
  8. Riede L, Grube B, Gruenwald J. Larch arabinogalactan effects on reducing incidence of upper respiratory tract infections. Curr Med Res Opin 2013;29(3):251-8.

See these in context on the Larch Arabinogalactan monograph →

Beta-glucans 11 references
  1. Katz, D. L., Nawaz, H., Boukhalil, J., Giannamore, V., Chan, W., Ahmadi, R., and Sarrel, P. M. Acute effects of oats and vitamin E on endothelial responses to ingested fat. Am.J.Prev.Med. 2001;20(2):124-129. PubMed
  2. Keenan, J. M., Pins, J. J., Frazel, C., Moran, A., and Turnquist, L. Oat ingestion reduces systolic and diastolic blood pressure in patients with mild or borderline hypertension: a pilot trial. J.Fam.Pract. 2002;51(4):369.
  3. Maki, K. C., Galant, R., Samuel, P., Tesser, J., Witchger, M. S., Ribaya-Mercado, J. D., Blumberg, J. B., and Geohas, J. Effects of consuming foods containing oat beta-glucan on blood pressure, carbohydrate metabolism and biomarkers of oxidative stress i
  4. Bergendiova, K., Tibenska, E., and Majtan, J. Pleuran (beta-glucan from Pleurotus ostreatus) supplementation, cellular immune response and respiratory tract infections in athletes. Eur.J.Appl.Physiol 2011;111(9):2033-2040.
  5. Talbott S, Talbott J. Effect of beta 1,3/1,6 glucan on respiratory tract infection symptoms and mood state in marathon athletes. J Sports Sci Med 2009;8(4):509-515.
  6. Feldman S, Schwartz HI Kalman DS Mayers A Kohrman HM Clemens R Krieger DR. Randomized phase II clinical trials of Wellmune WGP® for immune support during cold and flu season. The Journal of Applied Research 2009;9(1-2):30-42.
  7. McFarlin BK, Carpenter KC, Davidson T, McFarlin MA. Baker's yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise. J Diet Suppl. 2013;10(3):171-83. PubMed
  8. Jesenak M, Urbancek S, Majtan J, Banovcin P, Hercogova J. ß-Glucan-based cream (containing pleuran isolated from pleurotus ostreatus) in supportive treatment of mild-to-moderate atopic dermatitis. J Dermatolog Treat 2016;27(4):351-4.
  9. Mah E, Kaden VN, Kelley KM, Liska DJ. Beverage containing dispersible yeast ß-glucan decreases cold/flu symptomatic days after intense exercise: a randomized controlled trial. J Diet Suppl 2020;17(2):200-10. PubMed
  10. Zhong K, Liu Z, Lu Y, Xu X. Effects of yeast ß-glucans for the prevention and treatment of upper respiratory tract infection in healthy subjects: a systematic review and meta-analysis. Eur J Nutr. 2021. PubMed
  11. Cardenas FI, Mauguen A, Cheung IY, et al. Phase I trial of oral yeast-derived ß-glucan to enhance anti-GD2 immunotherapy of resistant high-risk neuroblastoma. Cancers (Basel) 2021;13(24):6265. PubMed

See these in context on the Beta-glucans monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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