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Dietary supplement

Eyebright Extract Powder 500 mg Ingredients & Drug Interactions

by BulkSupplements.com

Eyebright Extract Powder 500 mg label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Eyebright Extract Powder 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Eyebright Extract Powder 500 mg is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for eye irritation and redness, conjunctivitis (pink eye), eye strain.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Eyebright Aerial Part Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Eyebright Extract Powder 500 mg by BulkSupplements.com

Ask about any prescription or over-the-counter medication and we check it for interactions with Eyebright Extract Powder 500 mg by BulkSupplements.com — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Eyebright Extract Powder 500 mg by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product is a single-ingredient supplement: eyebright aerial part extract, 500 mg per serving. Eyebright is an herb traditionally used for eye health and respiratory symptoms.

The product contains no other active ingredients and no inactive fillers or binders listed.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Eyebright's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: eye health and comfort support.
  • We looked for evidence on: Asthenopia (eye strain), Conjunctivitis, Allergic rhinitis (hay fever), eye irritation, eye redness, ocular comfort.
  • The closest evidence on file: Eyebright is rated "Insufficient Reliable Evidence To Rate" for Allergic rhinitis (hay fever) (Natural Medicines).
  • Also on file: Eyebright is rated "Insufficient Reliable Evidence To Rate" for Asthenopia (eye strain), Conjunctivitis.

The evidence for eyebright doesn't support any reliable benefit yet. Our data shows insufficient reliable evidence to rate it for allergic rhinitis (hay fever), common cold, cough, sore throat (pharyngitis), sinus inflammation (rhinosinusitis), or cancer.

In other words, we don't have solid trial data backing these uses — that doesn't mean it doesn't work, but it does mean we can't confirm it does.

The evidence, ingredient by ingredient Eyebright

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Eyebright is generally well tolerated in small amounts as a tea, but direct application to the eye — especially with homemade or non-sterile preparations — carries risk and isn't advised. Orally, some people report confusion, headache, nausea, constipation, cough, shortness of breath, and nasal congestion, though these aren't common in trial data.

Safety hasn't been established in pregnancy, so the data advises against use. There isn't enough safety information for breastfeeding — talk with your doctor or pharmacist about whether it's right for you.

Side effects, ingredient by ingredient Eyebright

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Eyebright.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your diabetes medications before taking this product. Eyebright may increase the risk of low blood sugar (a Moderate-severity interaction) with insulin, metformin, and other antidiabetes drugs.

If you're on any diabetes medication, bring this supplement to your pharmacist.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Eyebright extract may interest you if you're exploring traditional herbal remedies for eye or respiratory health, but the evidence for its benefits isn't established yet. If you take diabetes medication, check with your pharmacist first — eyebright may lower your blood sugar.

Pregnancy or breastfeeding? Talk with your doctor before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Eyebright Extract Powder 500 mg, straight from the product label.

Brand BulkSupplements.com
Barcode (UPC) X001N1GRR1
Net contents 1 Kilogram(s); 35.3 Ounce(s)
Market status On market
Date entered into DSLD Apr 24, 2025
DSLD ID 330826
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Eyebright Extract Powder 500 mg by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
500 mg
Maximum serving Sizes:
500 mg
Servings per container
2000
UPC/BARCODE
X001N1GRR1
IngredientAmount% DV
Eyebright Aerial Part Extract500 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Eyebright Extract Powder 500 mg per serving

Brand IP Statement(s)

BulkSupplements.com Clean & pure bulk supplements

Formulation

Color may vary

Free of: Added sugar, soy, dairy, yeast, gluten, additives

FDA Disclaimer Statement

Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Always consult a physician before taking any dietary supplement.

Keep out of reach of children.

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take 500 mg (about 1/5 tsp) once or twice daily, or as directed by a physician.

General Statements

Use an accurate milligram scale. New

Storage

Contents are sold by weight, not volume. Settling may occur. Store in a dry, cool place

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Eyebright Extract Powder 500 mg by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Eyebright Extract Powder 500 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Eyebright Extract Powder 500 mg by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size500 mg Dosage formPowder Servings per container2000 Amounts shown are per serving.

Eyebright Aerial Part Extract

Interacts with
86 drugs
500 mg per serving Form: Euphrasia officinalis Aerial Part Extract

Eyebright is a traditional herb long used for minor eye irritation, redness, and allergy symptoms, but high-quality human studies are very limited. Th...

Eyebright Aerial Part Extract monograph & interactions
Interaction report

Eyebright Extract Powder 500 mg by BulkSupplements.com Drug Interactions

Want to check YOUR meds against Eyebright Extract Powder 500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Eyebright Aerial Part Extract 86

Individual Drug Interactions

The ingredients in Eyebright Extract Powder 500 mg interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Eyebright Extract Powder 500 mg interact with drugs. Each result below shows which ingredient is responsible. Eyebright Aerial Part Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Eyebright Extract Powder 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Eyebright Aerial Part Extract1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that eyebright lowers blood glucose levels.

Likelihood Possible Evidence D
Eyebright Aerial Part Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Eyebright Extract Powder 500 mg, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Rd
City
Henderson
State
NV
ZipCode
89011
Web Address
BulkSupplements.com
Pharmacist Counseling Corner

Eyebright Extract Powder 500 mg by BulkSupplements.com: Common Questions

Does Eyebright Extract Powder 500 mg by BulkSupplements.com interact with any medications?
Yes. Based on its ingredients, Eyebright Extract Powder 500 mg has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Eyebright Extract Powder 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is eyebright and what's it used for?
Eyebright is an herb — the aerial parts (leaves, stems, flowers) are extracted and dried into powder. It's traditionally used for eye health and symptoms like cough and sore throat, though our data shows the evidence isn't strong enough yet to confirm those benefits.
Can I use eyebright if I take diabetes medication?
You need to check with your pharmacist first. Animal research suggests eyebright lowers blood glucose, so taking it with diabetes drugs could increase your risk of low blood sugar (hypoglycemia) — a Moderate-severity interaction. Your pharmacist can help you decide whether it's safe for your situation and whether you need closer blood sugar monitoring.
Is it safe to put this powder directly in my eye?
No, we don't recommend it. The safety data warns against using eyebright directly in the eye, especially homemade or non-sterile preparations, because of infection and irritation risk. Stick to taking it by mouth as directed.
What side effects might I experience?
Oral use has been reported to cause confusion, headache, nausea, constipation, cough, shortness of breath, and nasal congestion in some people — though these aren't common. Stop and call your pharmacist if you notice any unusual symptoms.
Is it safe during pregnancy or breastfeeding?
The safety data advises against eyebright in pregnancy because it hasn't been studied enough. If you're breastfeeding, there also isn't enough safety information — talk with your doctor or pharmacist about whether it's right for you before starting.
Does eyebright actually work for allergies or a cold?
Our data shows insufficient reliable evidence to rate it for hay fever, common cold, cough, sore throat, or sinus issues. That means we don't have solid trial data backing those claims yet — not that it definitely doesn't work, but we can't confirm it does.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Eyebright Extract Powder 500 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Eyebright Extract Powder 500 mg label
Go deeper

The Full Monographs Behind Eyebright Extract Powder 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Eyebright

Interacts with 86 drugs

Eyebright is a traditional herb long used for minor eye irritation, redness, and allergy symptoms, but high-quality human studies are very limited. There is not enough reliable evidence to c...

Read the full Eyebright monograph →
Sources

Sources & How We Checked

Eyebright Extract Powder 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Eyebright 4 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.
  3. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  4. Porchezhian, E., Ansari, S. H., and Shreedharan, N. K. Antihyperglycemic activity of Euphrasia officinale leaves. Fitoterapia 2000;71(5):522-526. PubMed

See these in context on the Eyebright monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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