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Dietary supplement

Eyebright Ingredients & Drug Interactions

by Nature's Answer

Eyebright label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Eyebright against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Eyebright is a dietary supplement by Nature's Answer with 1 active ingredient. Its ingredients are commonly taken for eye irritation and redness, conjunctivitis (pink eye), eye strain.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Eyebright (Euphrasia officinalis) whole herb extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Eyebright by Nature's Answer

Ask about any prescription or over-the-counter medication and we check it for interactions with Eyebright by Nature's Answer — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Eyebright by Nature's Answer

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains a single active ingredient: eyebright (Euphrasia officinalis) whole herb extract, supplied as a liquid. The extract is prepared in purified water, vegetable glycerin, and 12–15% certified organic alcohol.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Eyebright's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: promotes eye health.
  • We looked for evidence on: Asthenopia (eye strain), Conjunctivitis, eye irritation, eye redness, allergy-related eye symptoms.
  • The closest evidence on file: Eyebright is rated "Insufficient Reliable Evidence To Rate" for Asthenopia (eye strain) (Natural Medicines).
  • Also on file: Eyebright is rated "Insufficient Reliable Evidence To Rate" for Conjunctivitis.

The evidence we hold doesn't establish eyebright's effectiveness for the conditions it's commonly used for — allergic rhinitis (hay fever), common cold, cough, sore throat (pharyngitis), sinus congestion (rhinosinusitis), or cancer. The data on file rates all of these as having insufficient reliable evidence to judge whether it works.

The evidence, ingredient by ingredient Eyebright

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Eyebright taken orally is generally well tolerated in small amounts as a tea. However, the safety data advises against use during pregnancy and while breastfeeding — the information we hold is not sufficient to confirm it's safe in either case, so talk with your doctor or pharmacist about whether it's right for you if you're pregnant or nursing.

Oral side effects reported include confusion, headache, nausea, constipation, cough, shortness of breath (dyspnea), and nasal congestion. Additionally, using homemade or non-sterile preparations directly in the eye carries risk and isn't recommended.

Side effects, ingredient by ingredient Eyebright

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Eyebright.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs (insulin, metformin, or other blood sugar–lowering medications), talk with your doctor or pharmacist before adding this product — eyebright may lower blood glucose and increase the risk of low blood sugar.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Eyebright may be worth considering if you're looking to support eye or respiratory health, though the evidence for its effectiveness hasn't been established in the data we hold. If you take any diabetes medication, clear it with your doctor or pharmacist first — it may lower blood sugar.

Pregnancy, breastfeeding, and direct eye use all warrant a conversation with your healthcare provider before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Eyebright, straight from the product label.

Brand Nature's Answer
Barcode (UPC) 083000002588
Net contents 1 fl. Oz.; 30 mL
Market status On market
Date entered into DSLD Feb 25, 2019
DSLD ID 188725
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Eyebright by Nature's Answer, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
2 mL
Servings per container
15
UPC/BARCODE
083000002588
IngredientAmount% DV
Eyebright (Euphrasia officinalis) whole herb extract550 mg--

Other ingredients: purified Water, Vegetable Glycerin, 12-15% certified organic Alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

Gluten Free

K Parve

Bio-Chelated Cold Extraction Process

Formula

K Parve

Euphrasia officinalis Made from 2,000 mg Eyebright

Low Alcohol

General

9235 Rev. 11/17 1059

General Statements

Since 1972 Promotes eye health

Brand IP Statement(s)

Discover Nature's Answer

Our alcohol extracts are produced using our cold Bio-Chelated proprietary extraction process, yielding a Holistically Balanced Advanced Botanical Fingerprint extract in the same synergistic ratios as in the plant.

2017 Nature's Answer

Formulation

Gluten-Free

FDA Statement of Identity

Herbal Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement take 1-2 mL (28-56 drops) three (3) times a day in a small amount of water. Shake well.

Precautions

Keep out of reach of children.

Warning: Do not use if pregnant or nursing.

Do not use if safety seal is damaged or missing.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Eyebright by Nature's Answer label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Eyebright label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Eyebright by Nature's Answer

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container15 Amounts shown are per serving.

Eyebright (Euphrasia officinalis) whole herb extract

Interacts with
86 drugs
550 mg per serving

Eyebright is a traditional herb long used for minor eye irritation, redness, and allergy symptoms, but high-quality human studies are very limited. Th...

Eyebright (Euphrasia officinalis) whole herb extract monograph & interactions

Other (inactive) ingredients: Purified Water, Vegetable Glycerin, 12-15% certified organic Alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Eyebright by Nature's Answer Drug Interactions

Want to check YOUR meds against Eyebright?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Eyebright (Euphrasia officinalis) whole herb extract 86

Individual Drug Interactions

The ingredients in Eyebright interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Eyebright interact with drugs. Each result below shows which ingredient is responsible. Eyebright (Euphrasia officinalis) whole herb extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Eyebright with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Eyebright (Euphrasia officinalis) whole herb extract1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that eyebright lowers blood glucose levels.

Likelihood Possible Evidence D
Eyebright (Euphrasia officinalis) whole herb extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Eyebright, from the product label.

Nature's Answer

See all Nature's Answer products
Name
Nature's Answer
Street Address
85 Commerce Drive
City
Hauppauge
State
NY
ZipCode
11788
Phone Number
(800) 439-2324
Web Address
www.naturesanswer.com
Pharmacist Counseling Corner

Eyebright by Nature's Answer: Common Questions

Does Eyebright by Nature's Answer interact with any medications?
Yes. Based on its ingredients, Eyebright has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Eyebright contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I use eyebright if I'm pregnant or nursing?
The safety data we hold advises against it. There isn't enough information to confirm it's safe during pregnancy or breastfeeding, so talk with your doctor or pharmacist about what's right for you in either case.
What side effects can eyebright cause?
Orally, it's been reported to cause confusion, headache, nausea, constipation, cough, shortness of breath, and nasal congestion. If you have eye symptoms or respiratory issues, mention this product to your doctor.
Does eyebright actually work for hay fever or a cough?
The evidence we hold doesn't establish that it works for allergic rhinitis, cough, or other respiratory and eye conditions. The data rates these uses as having insufficient reliable evidence to judge.
Can I put this liquid directly in my eyes?
The safety data cautions against using homemade or non-sterile preparations directly in the eye — there's a real risk. Stick to taking it orally or as a tea unless your doctor advises otherwise.
Is this safe if I take diabetes medication?
Animal research suggests eyebright lowers blood glucose, so it could increase the risk of low blood sugar when you're on a diabetes drug. Talk with your doctor or pharmacist before starting — they may need to monitor your blood sugar or adjust your dose.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Eyebright is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Eyebright label
Go deeper

The Full Monographs Behind Eyebright’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Eyebright

Interacts with 86 drugs

Eyebright is a traditional herb long used for minor eye irritation, redness, and allergy symptoms, but high-quality human studies are very limited. There is not enough reliable evidence to c...

Read the full Eyebright monograph →
Sources

Sources & How We Checked

Eyebright's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Eyebright 4 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.
  3. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  4. Porchezhian, E., Ansari, S. H., and Shreedharan, N. K. Antihyperglycemic activity of Euphrasia officinale leaves. Fitoterapia 2000;71(5):522-526. PubMed

See these in context on the Eyebright monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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