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Dietary supplement

False Unicorn Ingredients & Drug Interactions

by Nature's Sunshine

False Unicorn label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking False Unicorn against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

False Unicorn is a dietary supplement by Nature's Sunshine with 1 active ingredient. Its ingredients are commonly taken for menstrual cramps, menopausal symptoms, female infertility support.Based on those ingredients, 740 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are False Unicorn. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against False Unicorn by Nature's Sunshine

Ask about any prescription or over-the-counter medication and we check it for interactions with False Unicorn by Nature's Sunshine — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of False Unicorn by Nature's Sunshine

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: false unicorn root. It's a traditional herbal remedy historically used to support women's reproductive health, though clinical evidence for its effectiveness isn't established in our data.

The ingredient is enclosed in a capsule.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Glandular system support.
  • We looked for evidence on: Hormonal balance, Menstrual health, Endocrine function.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

We don't hold effectiveness ratings for false unicorn in our data, so we can't tell you whether it works for any particular purpose based on clinical evidence.

The evidence, ingredient by ingredient False Unicorn

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

False unicorn is generally well tolerated by mouth, but large doses have been reported to cause nausea and vomiting. Safety data in humans is limited.

The safety data advises against use in pregnancy because of its traditional use to affect the uterus and lack of safety information. There isn't enough safety information for breastfeeding, so talk with your doctor or pharmacist about whether it's right for you if you're nursing.

Side effects, ingredient by ingredient False Unicorn

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — False Unicorn.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: lithium.
  • For scale: 741 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking False Unicorn, check whether you're on any CYP2D6 substrates (antidepressants, pain relievers, heart rhythm medications, and others), CYP3A4 substrates (some blood pressure medications and chemotherapy drugs), or lithium. All three interactions are Moderate in severity and could affect how these medications work in your body.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

False Unicorn may be worth considering if you're interested in traditional herbal support for reproductive health, but it's important to check your medications first—it affects how your liver processes a large number of drugs. If you take any prescription medications, especially antidepressants, pain relievers, blood pressure meds, chemotherapy, or lithium, run them through the checker before you start.

Talk with your pharmacist about whether it's a good fit for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 25, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about False Unicorn, straight from the product label.

Brand Nature's Sunshine
Barcode (UPC) 099904002678
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Jan 25, 2012
DSLD ID 4473
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Kosher
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for False Unicorn by Nature's Sunshine, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
50
UPC/BARCODE
099904002678
IngredientAmount% DV
False Unicorn900 mg--

Other ingredients: Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Herbal Dietary Supplement

Suggested/Recommended/Usage/Directions

RECOMMENDATION Take two capsules with a meal twice daily.

General Statements

01000267010811

Glandular System Support

GUARANTEED PURE

Herb Specialists Since 1972

LOT:

Nature's Sunshine uses natural source materials in its products that are subject to color variation.

Product of U.S.A.

Brand IP Statement(s)

©2011 Nature's Sunshine Products, Inc.

Seals/Symbols

Ko PAREVE

QUALITY, SERVICE, INTEGRITY

Precautions

This bottle was sealed for your protection. Do not use if inner seal is missing or damaged.

General

Stock No. 267-1

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

False Unicorn by Nature's Sunshine label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

False Unicorn label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in False Unicorn by Nature's Sunshine

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container50 Amounts shown are per serving.

False Unicorn

Interacts with
740 drugs
900 mg per serving

False Unicorn is a North American plant whose root has long been used in traditional medicine for women's reproductive and menstrual concerns. There i...

False Unicorn monograph & interactions

Other (inactive) ingredients: Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

False Unicorn by Nature's Sunshine Drug Interactions

Want to check YOUR meds against False Unicorn?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
740Drugs
740 Moderate

Ingredients driving the most interactions

False Unicorn 740

Individual Drug Interactions

The ingredients in False Unicorn interact with 740 drugs. Click any drug to see the details.

1 of the 1 ingredient in False Unicorn interact with drugs. Each result below shows which ingredient is responsible. False Unicorn

Each ingredient & the kinds of drugs it affects

For each ingredient in False Unicorn with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

False Unicorn3 drug types · 740 drugs

Cytochrome P450 2D6 (Cyp2D6) Substrates

In vitro, false unicorn extract inhibits cytochrome P450 2D6 (CYP2D6) activity. Theoretically, false unicorn might increase the levels of CYP2D6 substrates. Some of drugs that are CYP2D6 substrates include amitriptyline (Elavil), clozapine (Clozaril), codeine, desipramine (Norpramin), donepezil (Aricept), fentanyl (Duragesic), flecainide (Tambocor), fluoxetine (Prozac), meperidine (Demerol), methadone (Dolophine), metoprolol (Lopressor, Toprol XL), olanzapine (Zyprexa), ondansetron (Zofran), tramadol (Ultram), trazodone (Desyrel), and others.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity. Theoretically, false unicorn might increase the levels of CYP3A4 substrates. Drugs that might be affected include some calcium channel blockers (diltiazem, nicardipine, verapamil), chemotherapeutic agents (etoposide, paclitaxel, vinblastine, vincristine, vindesine), antifungals (ketoconazole, itraconazole), glucocorticoids, cisapride (Propulsid), alfentanil (Alfenta), fentanyl (Sublimaze), losartan (Cozaar), fluoxetine (Prozac), midazolam (Versed), omeprazole (Prilosec), ondansetron (Zofran), propranolol (Inderal), fexofenadine (Allegra), and numerous others.

Likelihood Possible Evidence D
Lithium

False unicorn is thought to have diuretic properties. Theoretically, due to these potential diuretic effects, false unicorn might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
False Unicorn full monograph & interactions
The maker

Brand information

Manufacturer and brand details for False Unicorn, from the product label.

Nature's Sunshine

See all Nature's Sunshine products
Name
Nature's Sunshine Products, Inc
City
Spanish Fork
State
Utah
ZipCode
84660
Phone Number
1-800-223-8225
Web Address
www.naturessunshine.com
Pharmacist Counseling Corner

False Unicorn by Nature's Sunshine: Common Questions

Does False Unicorn by Nature's Sunshine interact with any medications?
Yes. Based on its ingredients, False Unicorn has a known interaction with 740 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
False Unicorn contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take False Unicorn if I'm pregnant?
No. The safety data advises against it in pregnancy because of its traditional use to affect the uterus and lack of safety information in pregnant people.
Can I take False Unicorn while breastfeeding?
There isn't enough safety information to know either way. Talk with your doctor or pharmacist for personalized advice about whether it's right for you.
What side effects might False Unicorn cause?
It's generally well tolerated by mouth. Large doses have been reported to cause nausea and vomiting, and safety data in humans is limited.
What is False Unicorn used for?
It's a traditional herbal remedy historically used to support women's reproductive health, but we don't have clinical evidence in our data about whether it works for any specific purpose.
Does this product have any fillers?
The only inactive ingredient listed is the capsule itself.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

False Unicorn label
Go deeper

The Full Monographs Behind False Unicorn’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

False Unicorn

Interacts with 740 drugs

False Unicorn is a North American plant whose root has long been used in traditional medicine for women's reproductive and menstrual concerns. There is very little reliable human research to...

Read the full False Unicorn monograph →
Sources

Sources & How We Checked

False Unicorn's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

False Unicorn 4 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  4. Ho SH, Singh M, Holloway AC, Crankshaw DJ. The effects of commercial preparations of herbal supplements commonly used by women on the biotransformation of fluorogenic substrates by human cytochromes P450. Phytother Res. 2011;25(7):983-9. PubMed

See these in context on the False Unicorn monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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