Interactions on record — worth a quick check against your medications. Based on 1 of 6 ingredients. Check your meds →
Dietary supplement

FLORASSIST Immune Health Ingredients & Drug Interactions

by Life Extension

FLORASSIST Immune Health label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking FLORASSIST Immune Health against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

FLORASSIST Immune Health is a dietary supplement by Life Extension with 6 active ingredients. Its ingredients are commonly taken for digestive health and bloating, diarrhea support, immune support.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bacillus subtilis CU1. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against FLORASSIST Immune Health by Life Extension

Ask about any prescription or over-the-counter medication and we check it for interactions with FLORASSIST Immune Health by Life Extension — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of FLORASSIST Immune Health by Life Extension

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 6 active ingredients.
  • “Immune Probiotic Blend” is a proprietary blend — the label doesn't break down how much of each component you get.

FLORASSIST Immune Health contains 6 active probiotic ingredients: an Immune Probiotic Blend made up of five strains—B. lactis BS01, L. plantarum LP01, L. plantarum LP02, L. rhamnosus LR04, and L. rhamnosus LR05—plus Bacillus subtilis CU1. These are all live beneficial bacteria meant to support digestive and immune health.

The capsule also contains several inactive ingredients: monoglyceride, microcrystalline cellulose, vegetable cellulose, maltodextrin, stearic acid, and silica. These are binders, fillers, and capsule materials that hold the product together.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Bacillus Subtilis's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: immune health support.
  • We looked for evidence on: immune function, infection prevention, microbiome.
  • The closest evidence on file: Bacillus Subtilis is rated "Insufficient Reliable Evidence To Rate" for Clostridioides difficile infection (Natural Medicines).

The evidence for Bacillus subtilis CU1 is mixed. It's rated possibly effective for antibiotic-associated diarrhea (diarrhea that happens after you've taken antibiotics).

For athletic performance, cirrhosis, constipation, atopic dermatitis (eczema), and diabetes, there isn't enough reliable evidence yet to say whether it works. We don't have effectiveness data on file for the other five strains in this product.

The evidence, ingredient by ingredient Bacillus Subtilis

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bacillus subtilis is generally well tolerated in healthy adults, but the safety data is limited and quality can vary by product and strain. In clinical trials, one person reported a headache, and diarrhea was reported rarely.

There are also rare cases on record of serious infections (bacteremia and meningitis) linked to frequent consumption of natto (soybeans fermented with a related B. subtilis variety), though these occurred in people who were already immunocompromised—very elderly, diabetic, or dealing with kidney disease or cancer. Because safety information is limited, it's best to talk with your doctor before starting this product, especially if you have a weakened immune system or other serious health conditions.

Side effects, ingredient by ingredient Bacillus Subtilis

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Bacillus Subtilis.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antibiotic drugs, check the timing with your doctor or pharmacist—antibiotics and this product should be spaced a few hours apart so the antibiotic doesn't kill the live organisms. No other interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

FLORASSIST Immune Health is a probiotic blend that may help with antibiotic-associated diarrhea, but evidence for other uses isn't established yet. If you take antibiotics, you'll want to separate them from this supplement to keep the probiotics working.

Talk with your doctor or pharmacist before you start, especially if you have immune issues or serious health conditions.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 25, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about FLORASSIST Immune Health, straight from the product label.

Brand Life Extension
Barcode (UPC) 037870212430
Net contents 30 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Oct 25, 2018
DSLD ID 182666
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for FLORASSIST Immune Health by Life Extension, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetarian Capsule(s)
Maximum serving Sizes:
1 Vegetarian Capsule(s)
UPC/BARCODE
037870212430
IngredientAmount% DV
Immune Probiotic Blend0 NP--
B. lactis BS010 NP--
L. plantarum LP010 NP--
L. plantarum LP020 NP--
L. rhamnosus LR040 NP--
L. rhamnosus LR050 NP--
Bacillus subtilis CU10 NP--

Other ingredients: Monoglyceride, Microcrystalline Cellulose, Vegetable Cellulose, Maltodextrin, Stearic Acid, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Scan for product info

Probiotic Support for a Healthy Immune Response

General

QE02124A

Suggested/Recommended/Usage/Directions

Read the entire label and follow directions carefully prior to use. Directions: Take one (1) capsule daily, with or without food, or as recommended by a healthcare practitioner.

Formulation

Non-GMO

Storage

Store tightly closed in a cool, dry place.

Precautions

Warnings: Keep out of reach of children.

Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Contains soybeans.

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Formula

Contains soybeans.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

FLORASSIST Immune Health by Life Extension label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

FLORASSIST Immune Health label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in FLORASSIST Immune Health by Life Extension

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Vegetarian Capsule(s) Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Immune Probiotic Blend

0 NP per serving
  • › B. lactis BS01
  • › L. plantarum LP01
  • › L. plantarum LP02
  • › L. rhamnosus LR04
  • › L. rhamnosus LR05

Bacillus subtilis CU1

Interacts with
182 drugs
0 NP per serving

Bacillus subtilis is a spore-forming probiotic bacterium found in soil and some fermented foods, and it is used mainly to support gut health and diges...

Bacillus subtilis CU1 monograph & interactions

Other (inactive) ingredients: Monoglyceride, Microcrystalline Cellulose, Vegetable Cellulose, Maltodextrin, Stearic Acid, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

FLORASSIST Immune Health by Life Extension Drug Interactions

Want to check YOUR meds against FLORASSIST Immune Health?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Bacillus subtilis CU1 182

Individual Drug Interactions

The ingredients in FLORASSIST Immune Health interact with 182 drugs. Click any drug to see the details.

1 of the 6 ingredients in FLORASSIST Immune Health interact with drugs. Each result below shows which ingredient is responsible. Bacillus subtilis CU1

Each ingredient & the kinds of drugs it affects

For each ingredient in FLORASSIST Immune Health with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bacillus subtilis CU11 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B. subtilis.
Since B. subtilis preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. subtilis preparations by at least 2 hours.

Likelihood Probable Evidence D
Bacillus subtilis CU1 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for FLORASSIST Immune Health, from the product label.

Life Extension

See all Life Extension products
Name
Quality Supplements and Vitamins, Inc.
City
Ft. Lauderdale
State
FL
ZipCode
33309
Phone Number
1-866-280-2852
Web Address
LifeExtension.com
Pharmacist Counseling Corner

FLORASSIST Immune Health by Life Extension: Common Questions

Does FLORASSIST Immune Health by Life Extension interact with any medications?
Yes. Based on its ingredients, FLORASSIST Immune Health has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
FLORASSIST Immune Health contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm on antibiotics?
You can, but timing matters. Taking antibiotics at the same time as this supplement may reduce how well the probiotic works because the antibiotic can kill the live bacteria in the capsule. Ask your doctor or pharmacist to help you space them out—usually a few hours apart works.
What are these strains supposed to do?
They're live beneficial bacteria meant to support digestive and immune health. The Bacillus subtilis in here is possibly effective for diarrhea that happens after you've taken antibiotics. For other uses like athletic performance or constipation, the evidence isn't strong enough yet to say.
Are there any side effects?
Bacillus subtilis is generally well tolerated. In clinical trials, one person reported a headache, and diarrhea was reported rarely. Serious infections are extremely rare and happened in people who were already very sick or immunocompromised.
Is this safe if I'm pregnant or breastfeeding?
We don't have enough safety data for pregnant or breastfeeding people. Talk with your doctor or pharmacist to see if this product is right for you in that situation.
Why can't you check the other four strains for interactions?
We simply don't hold interaction data for B. lactis BS01, L. plantarum LP01, L. plantarum LP02, L. rhamnosus LR04, and L. rhamnosus LR05 yet. That doesn't mean they're safe with all medications—it means we haven't gathered that information.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if FLORASSIST Immune Health is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

FLORASSIST Immune Health label
Go deeper

The Full Monographs Behind FLORASSIST Immune Health’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bacillus Subtilis

Interacts with 182 drugs

Bacillus subtilis is a spore-forming probiotic bacterium found in soil and some fermented foods, and it is used mainly to support gut health and digestion. Early research is promising for ce...

Read the full Bacillus Subtilis monograph →
Sources

Sources & How We Checked

FLORASSIST Immune Health's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bacillus Subtilis 10 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Lampropoulos PK, Gkentzi D, Tzifas S, Dimitriou G. Neonatal sepsis due to Bacillus subtilis. Cureus 2021;13(9):e17692. PubMed
  3. La Jeon Y, Yang JJ, Kim MJ, et al. Combined Bacillus licheniformis and Bacillus subtilis infection in a patient with oesophageal perforation. J Med Microbiol 2012;61(Pt 12):1766-1769. PubMed
  4. Wallet F, Crunelle V, Roussel-Delvallez M, Fruchart A, Saunier P, Courcol RJ. Bacillus subtilis as a cause of cholangitis in polycystic kidney and liver disease. Am J Gastroenterol 1996;91(7):1477-8.
  5. Velasco E, Martins CA, Tabak D, Bouzas LF. "Bacillus subtilis" infection in a patient submitted to a bone marrow transplantation. Rev Paul Med 1992;110(3):116-7.
  6. Kato A, Yoshifuji A, Komori K, et al. A case of Bacillus subtilis var. natto bacteremia caused by ingestion of natto during COVID-19 treatment in a maintenance hemodialysis patient with multiple myeloma. J Infect Chemother 2022;28(8):1212-1215. PubMed
  7. Freedman KE, Hill JL, Wei Y, et al. Examining the gastrointestinal and immunomodulatory effects of the novel probiotic Bacillus subtilis DE111. Int J Mol Sci 2021;22(5):2453. PubMed
  8. Lefevre M, Racedo SM, Denayrolles M, et al. Safety assessment of Bacillus subtilis CU1 for use as a probiotic in humans. Regul Toxicol Pharmacol 2017;83:54-65. PubMed
  9. Hanifi A, Culpepper T, Mai V, et al. Evaluation of Bacillus subtilis R0179 on gastrointestinal viability and general wellness: a randomised, double-blind, placebo-controlled trial in healthy adults. Benef Microbes 2015;6(1):19-27. PubMed
  10. Tokano M, Tarumoto N, Imai K, et al. A case of bacterial meningitis caused by Bacillus subtilis var. natto. Intern Med. 2022. Epub ahead of print.

See these in context on the Bacillus Subtilis monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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