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Dietary supplement

Formula 90 Ingredients & Drug Interactions

by DC

Formula 90 label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Formula 90 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Formula 90 is a dietary supplement by DC with 1 active ingredient. Its ingredients are commonly taken for memory and cognitive support, anxiety and stress, anti-aging.Based on those ingredients, 82 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Pregnenolone. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Formula 90 by DC

Ask about any prescription or over-the-counter medication and we check it for interactions with Formula 90 by DC — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Formula 90 by DC

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

DC Formula 90 is a single-ingredient supplement containing pregnenolone, a hormone precursor your body naturally produces. Pregnenolone serves as a starting material your body uses to make other steroid hormones, including estrogen, progesterone, and testosterone.

The capsule itself is made from vegetable cellulose and gelatin, with vegetable magnesium stearate and silica as inactive ingredients to help with manufacturing and stability.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Pregnenolone product and its label doesn't state a use — see Pregnenolone's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence on pregnenolone for treating specific health conditions isn't established in our data. The supplement has been studied for alcohol use disorder, Alzheimer disease, autism spectrum disorder, back pain, and bipolar disorder, but all of these show insufficient reliable evidence to rate how well it actually works.

If you're considering it for any of these reasons, talk with your doctor about what the current research really supports.

The evidence, ingredient by ingredient Pregnenolone

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pregnenolone is generally well tolerated when taken by mouth. The most common side effects reported in studies include acne, agitation, diarrhea, drowsiness, excitement, hair loss, sweating, and tremor.

Skin abscesses and hair loss have been documented. One person reported a rash with a burning sensation on the hands that seemed to clear on its own, possibly a light sensitivity reaction.

Some users have reported mood changes like depression or increased appetite, though it's unclear whether pregnenolone caused these. Because pregnenolone is a hormone with limited human safety data, use only under guidance from your healthcare professional.

The safety data advises against it during pregnancy due to unknown risks, and there isn't enough information to use it safely while breastfeeding—talk with your doctor or pharmacist before taking it if you're pregnant, planning to become pregnant, or nursing.

Side effects, ingredient by ingredient Pregnenolone

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Pregnenolone.
  • The most serious interaction on file is rated Moderate.
  • For scale: 82 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take estrogens, progestins, progesterone, or testosterone—including birth control pills or hormone replacement therapy—or if you use benzodiazepines for anxiety or sleep, double-check with your doctor or pharmacist before starting pregnenolone. All of these are Moderate severity interactions: hormones may be stronger, and sedatives may be less effective.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

DC Formula 90 is a single-ingredient pregnenolone supplement that may interact with hormone medications, birth control, and benzodiazepines. The evidence for treating specific conditions isn't established yet.

Because it's a hormone with limited safety data, it requires guidance from a healthcare professional. Check your medications before starting, and talk with your own doctor or pharmacist about whether it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Formula 90, straight from the product label.

Brand DC
Net contents 0 Not Present
Market status On market
Date entered into DSLD Feb 25, 2021
DSLD ID 244560
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Formula 90 by DC, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
IngredientAmount% DV
Pregnenolone10 mg--

Other ingredients: Vegetable Cellulose, Gelatin, Vegetable Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Pregnenolone is a neurosteroid produced in the cells. Pregnenolone is converted into DHEA or Progesterone which are used to produce various natural hormones. This product contains the highest quality Pregnenolone available in supplement form.

Pregnenolone

Formulation

Mfg. in an FDA Registered Facility using Good Manufacturing Practices (GMPs)

Conforms to USP <2091> for weight. Meets USP <2040> disintegration for maximum bioavailability. Made in USA

Gluten free

Precautions

Tamper Evident: Do not use this product if imprinted foil seal under cap is broken or missing.

Keep out of reach of children.

Warnings: Do not use this product if you are pregnant, nursing, capable of bearing children, or taking any prescription medication, including any hormone product.

Consult your doctor before using this product if you have any health condition.

Storage

Keep tightly closed. Store at room temperature: 59 degrees - 86 degrees F (15 degrees to 30 degrees C).

Seals/Symbols

Quali Pure

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Consult warnings before using this product. Take one capsule daily as a dietary supplement.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Formula 90 by DC label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Formula 90 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Formula 90 by DC

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Pregnenolone

Interacts with
82 drugs
10 mg per serving

Pregnenolone is a hormone your body makes naturally and a building block for other hormones like cortisol, DHEA, estrogen, and testosterone. It is sol...

Pregnenolone monograph & interactions

Other (inactive) ingredients: Vegetable Cellulose, Gelatin, Vegetable Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Formula 90 by DC Drug Interactions

Want to check YOUR meds against Formula 90?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
82Drugs
82 Moderate

Ingredients driving the most interactions

Pregnenolone 82

Individual Drug Interactions

The ingredients in Formula 90 interact with 82 drugs. Click any drug to see the details.

1 of the 1 ingredient in Formula 90 interact with drugs. Each result below shows which ingredient is responsible. Pregnenolone

Each ingredient & the kinds of drugs it affects

For each ingredient in Formula 90 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Pregnenolone5 drug types · 82 drugs

Benzodiazepines

Concomitant use of pregnenolone may reduce the effects of benzodiazepines.
Very preliminary clinical research shows that chronic use of pregnenolone reduces sedative effects of diazepam when compared with chronic use of placebo. This effect may be related to the activity of pregnenolone at GABAA receptors.

Likelihood Probable Evidence B
Estrogens

Theoretically, taking pregnenolone might enhance the effects of estrogens.
Pregnenolone is a precursor for several steroid hormones, including estrogens.

Likelihood Possible Evidence D
Progesterone

Theoretically, taking pregnenolone might enhance the effects of progesterone.
In humans, some research shows that oral administration of pregnenolone can increase levels of progesterone. However, other research shows no effect on progesterone levels. It is possible the impact of pregnenolone on progesterone levels may be dose dependent.

Likelihood Possible Evidence D
Progestin

Theoretically, taking pregnenolone might enhance the effects of progestin.
Pregnenolone is a precursor for several steroid hormones, including progestin.

Likelihood Possible Evidence D
Testosterone

Theoretically, taking pregnenolone might enhance the effects of testosterone.
Pregnenolone is a precursor for several steroid hormones, including testosterone. However, preliminary clinical research shows that taking pregnenolone 30-500 mg orally daily for up to 8 weeks does not affect testosterone levels.

Likelihood Possible Evidence D
Pregnenolone full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Formula 90, from the product label.

DC

See all DC products
Name
Dee Cee Laboratories, Inc.
Street Address
304 Dee Cee Rd.
City
White House
State
TN
ZipCode
37188
Pharmacist Counseling Corner

Formula 90 by DC: Common Questions

Does Formula 90 by DC interact with any medications?
Yes. Based on its ingredients, Formula 90 has a known interaction with 82 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Formula 90 contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on birth control?
No without talking to your doctor first. Pregnenolone may enhance the effects of estrogens and progestins in birth control, and we're not sure how that would play out for you. Your doctor or pharmacist needs to weigh the risk with your specific pill or method.
What are the most common side effects?
Acne, agitation, diarrhea, drowsiness, excitement, hair loss, sweating, and tremor are the most common. Skin abscesses and hair loss have also been reported. Most people tolerate it, but these effects are worth knowing about.
Can I take this while pregnant or breastfeeding?
No. The safety data advises against pregnenolone in pregnancy because the risks aren't known. There's also not enough information to use it while breastfeeding. Talk with your doctor or pharmacist for personalized advice if you're pregnant, planning pregnancy, or nursing.
Does it actually work for Alzheimer disease or back pain?
The evidence isn't established in our data. Pregnenolone has been studied for both, but the research so far is too preliminary to say whether it helps. Your doctor can discuss what current research really shows.
Can I take this if I use anti-anxiety medication like Valium?
Not without checking with your doctor first. Early research suggests pregnenolone may weaken the sedative effects of benzodiazepines like diazepam, which could affect how well your medication works.
Why do I need a healthcare professional's guidance to use this?
Pregnenolone is a hormone with limited human safety data, so there's a lot we don't know yet about long-term use or how it affects different people. A healthcare professional can monitor you and catch any issues early.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Formula 90 is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Formula 90 label
Go deeper

The Full Monographs Behind Formula 90’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Pregnenolone

Interacts with 82 drugs

Pregnenolone is a hormone your body makes naturally and a building block for other hormones like cortisol, DHEA, estrogen, and testosterone. It is sold as a supplement for memory, mood, and...

Read the full Pregnenolone monograph →
Sources

Sources & How We Checked

Formula 90's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pregnenolone 6 references
  1. Devlin TM, ed. Textbook of Biochemistry With Clinical Correlations. third ed. New York: Wiley-Liss Inc., 1992.
  2. Fung LK, Libove RA, Phillips J, Haddad F, Hardan AY.Brief report: an open-label study of the neurosteroid pregnenolone in adults with autism spectrum disorder. J Autism Dev Disord 2014;44(11):2971-7. PubMed
  3. Brown ES, Park J, Marx CE, et al. A randomized, double-blind, placebo-controlled trial of pregnenolone for bipolar depression. Neuropsychopharmacology 2014;39(12):2867-73. PubMed
  4. Ritsner MS, Gibel A, Shleifer T, et al. Pregnenolone and dehydroepiandrosterone as an adjunctive treatment in schizophrenia and schizoaffective disorder: an 8-week, double-blind, randomized, controlled, 2-center, parallel-group trial. J Clin Psychiatry 20 PubMed
  5. Meieran SE, Reus VI, Webster R, Shafton R, Wolkowitz OM. Chronic pregnenolone effects in normal humans: attenuation of benzodiazepine-induced sedation. Psychoneuroendocrinology 2004;29(4):486-500. PubMed
  6. Marx CE, Keefe RS, Buchanan RW, et al. Proof-of-concept trial with the neurosteroid pregnenolone targeting cognitive and negative symptoms in schizophrenia. Neuropsychopharmacology 2009;34(8):1885-903. PubMed

See these in context on the Pregnenolone monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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