Interactions on record — worth a quick check against your medications. Based on 3 of 4 ingredients. Check your meds →
Dietary supplement

Gastronic Dr. Ingredients & Drug Interactions

by Native Remedies

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Gastronic Dr. is a dietary supplement by Native Remedies with 4 active ingredients. Its ingredients are commonly taken for sore throat and cough, heartburn and acid reflux, digestive upset and ibs.Based on those ingredients, 2,102 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Slippery Elm, Chamomile, Meadowsweet. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Gastronic Dr. by Native Remedies

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 4 active ingredients.
  • “Proprietary Formula” is a proprietary blend — the label gives one combined amount (800 mg) without saying how much of each component you get.

Gastronic Dr. contains 4 active ingredients: slippery elm, chamomile, meadowsweet, and kankerbossie. Slippery elm is an inner bark traditionally used to soothe the digestive tract; chamomile is an herb commonly used for digestive and calming support; meadowsweet is a plant traditionally used for digestive comfort; and kankerbossie is a lesser-known botanical.

The capsules also contain cellulose as an inactive ingredient.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: digestive health and gastrointestinal comfort.
  • We looked for evidence on: Constipation, Diarrhea, Irritable bowel syndrome (IBS), Peptic ulcers, Heartburn, Acid reflux — and 2 related terms.
  • The closest evidence on file: German Chamomile is rated "Insufficient Reliable Evidence To Rate" for Diarrhea (Natural Medicines).
  • Also on file: German Chamomile is rated "Insufficient Reliable Evidence To Rate" for Peptic ulcers.
  • Also on file: Slippery Elm is rated "Insufficient Reliable Evidence To Rate" for Constipation, Diarrhea, Irritable bowel syndrome (IBS), Peptic ulcers.

The effectiveness evidence for the individual ingredients in this product is not established in our data. Slippery elm, chamomile, meadowsweet, and kankerbossie all have insufficient reliable evidence to rate them for the digestive complaints they're traditionally used for—including constipation, diarrhea, and inflammatory bowel conditions.

This doesn't mean they don't work; it means rigorous clinical trials haven't yet proven their benefit in these uses.

The evidence, ingredient by ingredient Slippery Elm German Chamomile Meadowsweet

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Slippery elm is generally well tolerated for short-term use, though high-quality safety data are limited. It can occasionally cause allergic reactions like contact dermatitis or hives, and the pollen may trigger allergies.

Meadowsweet contains salicylates (plant compounds similar to aspirin) and in large doses may cause nausea and stomach upset. Safety data for all ingredients are limited, especially during pregnancy and breastfeeding—meadowsweet in particular should be avoided during both pregnancy and lactation.

Side effects, ingredient by ingredient Slippery Elm German Chamomile Meadowsweet

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Meadowsweet, German Chamomile, Slippery Elm.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 2,103 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Gastronic Dr., check your medications against these drug types: any oral medications (slippery elm may reduce how much your body absorbs), aspirin, choline magnesium trisalicylate (Trilisate), and salsalate (Disalcid). All carry Moderate-severity interactions.

Use the search tool on this page to verify your specific prescriptions and over-the-counter drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Gastronic Dr. may be worth considering if you're looking for traditional herbal digestive support, but you'll want to check it against any medications you take first—especially oral drugs and salicylate-containing pain relievers. Pregnant or breastfeeding?

Skip meadowsweet and talk to your pharmacist or doctor about the others. If you're taking multiple medications or have a sensitive stomach, run this by your pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Gastronic Dr., straight from the product label.

Brand Native Remedies
Barcode (UPC) 810845011174
Net contents 60 Veggie Capsule(s)
Market status On market
Date entered into DSLD Jun 25, 2025
DSLD ID 331818
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Gastronic Dr. by Native Remedies, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
810845011174
IngredientAmount% DV
Slippery Elm0 NP--
Chamomile0 NP--
Proprietary Formula800 mg--
Meadowsweet0 NP--
Kankerbossie0 NP--

Other ingredients: Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Tamper resistant for your protection. Use only if safety seal is intact.

Caution: Safety during pregnancy or breastfeeding has not yet been established.

Not recommended for people with a known sensitivity to plants of the Asteraceae family.

Formulation

Contains no artificial flavors or colorants. No gluten added.

All Native Remedies health products are especially formulated by experts in the field of natural health and are manufactured according to the highest pharmaceutical standards for maximum safety and effectiveness.

All-Natural Promotes ongoing digestive health & comfort

Suggested/Recommended/Usage/Directions

Suggested use: Take 1-2 capsules, 2-3 times daily.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

K Parve (Kosher) K-1604

Formula

K Parve (Kosher) K-1604

FDA Statement of Identity

Herbal Supplement

General Statements

Int'l.: +1-920-232-3275

See for yourself

Gastronic Dr. by Native Remedies label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Gastronic Dr. by Native Remedies

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Formula

800 mg per serving

Other (inactive) ingredients: Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Gastronic Dr. by Native Remedies Drug Interactions

Want to check YOUR meds against Gastronic Dr.?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
2,102Drugs
2,099 Moderate 3 Minor

Ingredients driving the most interactions

Slippery Elm 2,022
Chamomile 960

Each ingredient & the kinds of drugs it affects

For each ingredient in Gastronic Dr. with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Slippery Elm1 drug type · 2,022 drugs

Oral Drugs

Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Slippery elm inner bark contains mucilage, which may interfere with the absorption of orally administered drugs.

Likelihood Possible Evidence D

Chamomile9 drug types · 960 drugs

Cns Depressants

Theoretically, German chamomile might have additive effects when used with CNS depressants.
German chamomile has mild sedative effects. Theoretically, concomitant use with drugs with sedative properties can cause additive effects and side effects.

Likelihood Possible Evidence D
Contraceptive Drugs

Theoretically, large amounts of German chamomile might reduce the effectiveness of oral contraceptives.
In vitro, German chamomile has demonstrated antiestrogenic activity. Theoretically, concomitant use of large amounts of German chamomile might interfere with contraceptive drugs through competition for estrogen receptors.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, German chamomile might inhibit CYP2C9 and increase levels of drugs metabolized by these enzymes.
In vitro evidence shows that German chamomile might inhibit CYP2C9. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP2C9 in patients taking German chamomile.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, German chamomile might inhibit CYP2D6 and increase levels of drugs metabolized by these enzymes.
In vitro evidence shows that German chamomile might inhibit CYP2D6. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP2D6 in patients taking German chamomile.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
In vitro evidence shows that German chamomile might inhibit CYP3A4. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP3A4 in patients taking German chamomile.

Likelihood Possible Evidence D
Estrogens

Theoretically, large amounts of German chamomile might reduce the effectiveness of estrogens.
In vitro, German chamomile has demonstrated antiestrogenic activity. Theoretically, large amounts of German chamomile might interfere with hormone replacement therapy through competition for estrogen receptors.

Likelihood Possible Evidence D
Tamoxifen (Nolvadex)

Theoretically, large amounts of German chamomile might interfere with the activity of tamoxifen.
In vitro, German chamomile has demonstrated antiestrogenic activity.

Likelihood Possible Evidence D
Warfarin (Coumadin)

German chamomile might increase the effects of warfarin and increase the risk of bleeding.
In one case, a 70-year-old female taking warfarin developed retroperitoneal hematoma and bilateral recti muscle bleeding along with an INR of 7.9 following ingestion of German chamomile tea 4-5 cups daily and use of a topical chamomile-based lotion applied 4-5 times daily.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
In vitro and animal research shows that German chamomile might inhibit CYP1A2. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP1A2 in patients taking German chamomile.

Likelihood Possible Evidence D

Meadowsweet3 drug types · 39 drugs

Aspirin

Theoretically, meadowsweet might have an additive effect with other salicylate-containing drugs, such as aspirin.
Meadowsweet contains salicin, a plant salicylate; however, salicin doesn't seem to have the antiplatelet effects of aspirin.

Likelihood Possible Evidence D
Choline Magnesium Trisalicylate (Trilisate)

Theoretically, meadowsweet might have an additive effect with other salicylate-containing drugs, such as choline magnesium trisalicylate.
Meadowsweet contains salicin, a plant salicylate.

Likelihood Possible Evidence D
Salsalate (Disalcid)

Theoretically, meadowsweet might have an additive effect with other salicylate-containing drugs such as salsalate.
Meadowsweet contains salicin, a plant salicylate.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Gastronic Dr., from the product label.

Native Remedies

See all Native Remedies products
Name
Silver Star Brands
City
Oshkosh
State
WI
ZipCode
54906
Phone Number
1-877-289-1235
Web Address
www.nativeremedies.com
Pharmacist Counseling Corner

Gastronic Dr. by Native Remedies: Common Questions

Does Gastronic Dr. by Native Remedies interact with any medications?
Yes. Based on its ingredients, Gastronic Dr. has a known interaction with 2,102 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Gastronic Dr. contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
Meadowsweet should be avoided in both pregnancy and breastfeeding—the safety data advises against it. Slippery elm and chamomile don't have enough reliable safety information during pregnancy or breastfeeding either. Talk with your pharmacist or doctor for personalized advice before using this product if you're pregnant or nursing.
What does slippery elm do?
Slippery elm is an inner bark traditionally used to soothe and coat the digestive tract. It contains mucilage, which gives it that slippery texture—but rigorous evidence for its benefit in conditions like constipation, diarrhea, or inflammatory bowel disease isn't yet established in our data.
Can this interfere with my other medications?
Yes, potentially. Slippery elm's mucilage may slow how your body absorbs oral medications, and meadowsweet can interact with aspirin and similar salicylate drugs. Use the search tool on this page to check your specific medications before you start.
What side effects should I watch for?
Most people tolerate slippery elm well short-term, though allergic reactions like hives or contact dermatitis are possible—especially if you're sensitive to tree pollen. Meadowsweet in large doses may cause nausea and stomach upset, since it contains salicylates similar to aspirin.
Does this product actually work for digestive problems?
The evidence for slippery elm, chamomile, meadowsweet, and kankerbossie for digestive complaints like constipation and diarrhea is insufficient to rate—meaning rigorous clinical trials haven't yet proven their benefit. These are traditional uses, but solid proof is lacking in our data.
What's the proprietary formula in this product?
A proprietary formula means some ingredients are blended together, but all the individual components are listed separately on the label so we can check them for you. In this case, that's slippery elm, chamomile, meadowsweet, and kankerbossie.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Gastronic Dr. is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Gastronic Dr. label
Sources

Sources & How We Checked

Gastronic Dr.'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 21 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Slippery Elm 3 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. Czarnecki D, Nixon R, Bekhor P, and et al. Delayed prolonged contact urticaria from the elm tree. Contact Dermatitis 1993;28:196-197. PubMed

See these in context on the Slippery Elm monograph →

German Chamomile 15 references
  1. Subiza J, Subiza JL, Hinojosa M, et al. Anaphylactic reaction after the ingestion of chamomile tea; a study of cross-reactivity with other composite pollens. J Allergy Clin Immunol 1989;84:353-8. PubMed
  2. Budzinski JW, Foster BC, Vandenhoek S, Arnason JT. An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures. Phytomedicine 2000;7:273-82. PubMed
  3. Viola H, Wasowski C, Levi de Stein M, et al. Apigenin, a component of Matricaria recutita flowers, is a central benzodiazepine receptors-ligand with anxiolytic effects. Planta Med 1995;61:213-6.
  4. van Ketel WG. Allergy to Matricaria chamomilla. Contact Dermatitis 1982;8:143. PubMed
  5. van Ketel WG. Allergy to Matricaria chamomilla. Contact Dermatitis 1987;16:50-1. PubMed
  6. Hormann HP, Korting HC. Evidence for the efficacy and safety of topical herbal drugs in dermatology: part I: anti-inflammatory agents. Phytomedicine 1994;1:161-71. PubMed
  7. Avallone R, Zanoli P, Puia G, et al. Pharmacological profile of apigenin, a flavonoid isolated from Matricaria chamomilla. Biochem Pharmacol 2000;59:1387-94. PubMed
  8. Kassi E, Papoutsi Z, Fokialakis N, et al. Greek plant extracts exhibit selective estrogen receptor modulator (SERM)-like properties. J Agric Food Chem 2004;52:6956-61. PubMed
  9. Maliakal PP, Wanwimolruk S. Effect of herbal teas on hepatic drug metabolizing enzymes in rats. J Pharm Pharmacol 2001;53:1323-9. PubMed
  10. Segal R, Pilote L. Warfarin interaction with Matricaria chamomilla. CMAJ 2006;174:1281-2. PubMed
  11. Loggia RD, Traversa U, Scarcia V, et al. Depressive effects of Chamomilla recutita (L.) Rausch, tubular flowers, on central nervous system in mice. Pharmacol Res Commun 1982;14(2):153-162. PubMed
  12. Ganzera M, Schneider P, Stuppner H. Inhibitory effects of the essential oil of chamomile (Matricaria recutita L.) and its major constituents on human cytochrome P450 enzymes. Life Sci 2006;78(8):856-861. PubMed
  13. Benito P, Rodríguez-Perez R, García F, Juste S, Moneo I, Caballero ML. Occupational allergic rhinoconjunctivitis induced by Matricaria chamomilla with tolerance of chamomile tea. J Investig Allergol Clin Immunol. 2014;24(5):369-70. No abstract available.
  14. Braga FT, Santos AC, Bueno PC, et al. Use of Chamomilla recutita in the prevention and treatment of oral mucositis in patients undergoing hematopoietic stem cell transplantation: a randomized, controlled, phase II clinical trial. Cancer Nurs 2015;38(4):32 PubMed
  15. Sarris J, Ravindran A, Yatham LN, et al. Clinician guidelines for the treatment of psychiatric disorders with nutraceuticals and phytoceuticals: The World Federation of Societies of Biological Psychiatry (WFSBP) and Canadian Network for Mood and Anxiety T

See these in context on the German Chamomile monograph →

Meadowsweet 3 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

See these in context on the Meadowsweet monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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