Interactions on record — worth a quick check against your medications. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Ginseng Plus Ingredients & Drug Interactions

by Thorne

Ginseng Plus label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Ginseng Plus against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Ginseng Plus is a dietary supplement by Thorne with 3 active ingredients. Its ingredients are commonly taken for memory and cognitive support, nerve health, mood and anxiety.Based on those ingredients, 327 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lion's Mane Fruiting Body Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Ginseng Plus by Thorne

Ask about any prescription or over-the-counter medication and we check it for interactions with Ginseng Plus by Thorne — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Ginseng Plus by Thorne

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Ginseng Plus contains 3 active ingredients. Lion's mane mushroom fruiting body extract is included for cognitive and immune support.

The product also contains Greek Mountain Tea Aerial Parts Extract and Botalys, though we hold no data on the latter two. The capsules also contain inactive ingredients — hypromellose, microcrystalline cellulose, medium chain triglyceride, and calcium laurate — which are binders, fillers, and capsule material.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Lion's Mane Mushroom's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Stress and energy support.
  • We looked for evidence on: Anxiety, Athletic performance, Cognitive function, Depression, Memory, Fatigue — and 3 related terms.
  • The closest evidence on file: Lion's Mane Mushroom is rated "Insufficient Reliable Evidence To Rate" for Anxiety (Natural Medicines).
  • Also on file: Lion's Mane Mushroom is rated "Insufficient Reliable Evidence To Rate" for Athletic performance, Cognitive function, Depression, Memory.

The evidence for lion's mane mushroom is not yet established. Our data rates it as having insufficient reliable evidence for Alzheimer disease, anxiety, athletic performance, cancer, cognitive function, and cognitive impairment.

That doesn't mean it doesn't work — it means large, high-quality human trials haven't been done yet. We hold no effectiveness data for the other two ingredients.

The evidence, ingredient by ingredient Lion's Mane Mushroom

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 0 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lion's mane mushroom is generally well tolerated as a food, but long-term safety in supplement form hasn't been well studied. The most common side effects are gastrointestinal discomfort, nausea, and skin rash.

There isn't enough safety data to know whether lion's mane is safe in pregnancy or while breastfeeding — the safety data advises against it during both. Talk with your pharmacist or doctor before using this product if you're pregnant, trying to conceive, or nursing.

Side effects, ingredient by ingredient Lion's Mane Mushroom

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lion's Mane Mushroom.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 327 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take Ginseng Plus, double-check if you use any blood thinners or antiplatelet drugs (Moderate severity — bleeding risk), diabetes medications (Moderate — low blood sugar risk), or immune-suppressing drugs (Moderate — may reduce their effectiveness). We could not check Greek Mountain Tea Aerial Parts Extract or Botalys for interactions, so your pharmacist should review those as well.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and some safety-information gaps remain.

This product is worth considering if you're interested in cognitive or immune support, but the evidence isn't yet strong. The bigger question is whether you take blood thinners, diabetes drugs, or immune suppressants — if you do, check your exact medications with the tool on this page before you start.

Talk to your pharmacist about whether it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 21, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Ginseng Plus, straight from the product label.

Brand Thorne
Barcode (UPC) 693749015000
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD May 21, 2025
DSLD ID 328831
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Ginseng Plus by Thorne, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
693749015000
IngredientAmount% DV
Lion's Mane Fruiting Body Extract400 mg--
Greek Mountain Tea Aerial Parts Extract475 mg--
Botalys420 mg--

Other ingredients: Hypromellose, Microcrystalline Cellulose, Medium Chain Triglyceride, Calcium Laurate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Stress Energy

Gluten Free

Suggested/Recommended/Usage/Directions

Suggested use: Take 2 capsules daily or as recommended by your health-care practitioner.

Precautions

Tamper evident: Use only if bottle is sealed.

Warning: If pregnant, nursing, or trying to conceive, do not use this product.

Storage

Store tightly sealed in a cool, dry place.

Seals/Symbols

Manufactured in the USA using US & Imported ingredients

Formula

Ginseng Plus with Lion's Mane

This product uses BOTALYS red ginseng.

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Ginseng Plus by Thorne label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Ginseng Plus label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Ginseng Plus by Thorne

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Lion's Mane Fruiting Body Extract

Interacts with
327 drugs
400 mg per serving Form: Hericium erinaceus Fruiting Body Extract

Lion's mane is an edible mushroom that is popular as a 'nootropic' for memory, focus, and nerve health, but solid human evidence is still limited and...

Lion's Mane Fruiting Body Extract monograph & interactions

Greek Mountain Tea Aerial Parts Extract

475 mg per serving Form: Sideritis scardica Aerial Parts Extract

Botalys

420 mg per serving Form: Korean Red Ginseng Root Extract

Other (inactive) ingredients: Hypromellose, Microcrystalline Cellulose, Medium Chain Triglyceride, Calcium Laurate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Ginseng Plus by Thorne Drug Interactions

Want to check YOUR meds against Ginseng Plus?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
327Drugs
327 Moderate

Ingredients driving the most interactions

Lion's Mane Fruiting Body Extract 327

Individual Drug Interactions

The ingredients in Ginseng Plus interact with 327 drugs. Click any drug to see the details.

1 of the 3 ingredients in Ginseng Plus interact with drugs. Each result below shows which ingredient is responsible. Lion's Mane Fruiting Body Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Ginseng Plus with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lion's Mane Fruiting Body Extract3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
In vitro research suggests that lion's mane mushroom extracts can inhibit platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, lion's mane mushroom may have additive effects when used with antidiabetes drugs.
Animal research suggests that an aqueous extract of lion's mane mushroom can reduce serum glucose and increase serum insulin.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
In animal and in vitro research, lion's mane mushroom polysaccharides stimulate the immune system.

Likelihood Possible Evidence D
Lion's Mane Fruiting Body Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Ginseng Plus, from the product label.

Thorne

See all Thorne products
Name
Thorne Research, Inc.
Phone Number
1-800-228-1966
Pharmacist Counseling Corner

Ginseng Plus by Thorne: Common Questions

Does Ginseng Plus by Thorne interact with any medications?
Yes. Based on its ingredients, Ginseng Plus has a known interaction with 327 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Ginseng Plus contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is lion's mane mushroom safe during pregnancy?
There isn't enough safety data on lion's mane to know either way. The safety data advises against it during pregnancy. If you're pregnant or planning to be, talk with your pharmacist or doctor before taking this.
What side effects might I experience?
Lion's mane is generally well tolerated. The most common side effects in people who take it are gastrointestinal discomfort, nausea, and skin rash.
Can this help with memory or focus?
Lion's mane is used for cognitive support, but we don't yet have strong evidence in our data. The evidence is rated as insufficient for Alzheimer disease, cognitive impairment, cognitive function, and related conditions.
Does it affect blood clotting?
Test-tube research suggests lion's mane may slow blood clotting. If you take blood thinners or aspirin, check your exact medications with the tool on this page before starting — it's a Moderate-severity interaction.
What if I take diabetes medication?
Lion's mane may lower blood sugar on its own, so combined with diabetes drugs it could push your blood sugar too low. That's a Moderate interaction — talk to your pharmacist before you start.
Is this product a real ginseng?
No — despite the name, Ginseng Plus contains lion's mane mushroom, Greek Mountain Tea Extract, and Botalys. It doesn't contain ginseng root.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Ginseng Plus is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Ginseng Plus label
Go deeper

The Full Monographs Behind Ginseng Plus’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lion's Mane Mushroom

Interacts with 327 drugs

Lion's mane is an edible mushroom that is popular as a 'nootropic' for memory, focus, and nerve health, but solid human evidence is still limited and early. It is generally well tolerated as...

Read the full Lion's Mane Mushroom monograph →
Sources

Sources & How We Checked

Ginseng Plus's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lion's Mane Mushroom 6 references
  1. Product information for <em>Niaspan</em>. Abbott Laboratories. North Chicago, IL 60064. April 2015.
  2. Liang B, Guo Z, Xie F, Zhao A. Antihyperglycemic and antihyperlipidemic activities of aqueous extract of Hericium erinaceus in experimental diabetic rats. BMC Complement Altern Med. 2013;13:253. PubMed
  3. Mori K, Inatomi S, Ouchi K, Azumi Y, Tuchida T. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial. Phytother Res. 2009;23(3):367-72.
  4. Mori K, Kikuchi H, Obara Y, et al. Inhibitory effect of hericenone B from Hericium erinaceus on collagen-induced platelet aggregation. Phytomedicine. 2010;17(14):1082-5. PubMed
  5. Li IC, Chang HH, Lin CH, et al. Prevention of early Alzheimer's disease by erinacine A-enriched Hericium erinaceus mycelia pilot double-blind placebo-controlled study. Front Aging Neurosci 2020 Jun 3;12:155. doi: 10.3389/fnagi.2020.00155. PubMed
  6. Tian B, Liu R, Xu T, et al. Modulating effects of Hericium erinaceus polysaccharides on the immune response by regulating gut microbiota in cyclophosphamide-treated mice. J Sci Food Agric 2023;103(6):3050-3064.

See these in context on the Lion's Mane Mushroom monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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