Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

GlucoGold with Berberine Ingredients & Drug Interactions

by Doctors' Preferred

GlucoGold with Berberine label
See full label image
Tablet Or Pill Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking GlucoGold with Berberine against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

GlucoGold with Berberine is a dietary supplement by Doctors' Preferred with 4 active ingredients. Its ingredients are commonly taken for blood sugar support, type 2 diabetes, weight management.Based on those ingredients, 1,350 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are BerberPure, Cinnamon Bark Extract, Banaba leaf extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against GlucoGold with Berberine by Doctors' Preferred

Ask about any prescription or over-the-counter medication and we check it for interactions with GlucoGold with Berberine by Doctors' Preferred — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of GlucoGold with Berberine by Doctors' Preferred

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

GlucoGold with Berberine contains 4 active ingredients: banaba leaf extract, cinnamon bark extract, chromium, and berberine (supplied as BerberPure). Banaba and cinnamon are plant extracts traditionally used in blood sugar support; chromium is a mineral trace element; berberine is an alkaloid compound isolated from plants.

The tablet also contains several inactive ingredients — microcrystalline cellulose, croscarmellose sodium, dicalcium phosphate, silica, cellulose, hypromellose, stearic acid, glycerin, and hydroxypropyl cellulose — which serve as binders, fillers, and capsule materials.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Healthy blood sugar support.
  • We looked for evidence on: Diabetes, Impaired glucose tolerance (Prediabetes), Metabolic syndrome, Dyslipidemia, Hyperlipidemia, Obesity — and 4 related terms.
  • The strongest evidence on file: Chromium is rated "Likely Effective" for Chromium deficiency (Natural Medicines).
  • Also on file: Chromium is rated "Possibly Effective" for Diabetes.
  • Also on file: Berberine is rated "Possibly Effective" for Diabetes, Hyperlipidemia.

The evidence for these ingredients in managing blood sugar and related conditions is mixed. Chromium is rated Likely Effective for chromium deficiency and Possibly Effective for diabetes, though it's Possibly Ineffective for prediabetes.

Berberine is Possibly Effective for diabetes, high cholesterol (hyperlipidemia), high blood pressure, and PCOS, as well as for H. pylori infection. Banaba leaf extract and cinnamon bark extract both lack sufficient reliable evidence to rate their effectiveness for diabetes, prediabetes, or metabolic syndrome in the data we hold.

If you're considering this product for a specific condition, talk to your pharmacist about what the evidence actually supports for your situation.

The evidence, ingredient by ingredient Banaba Cassia Cinnamon Chromium Berberine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Berberine and banaba leaf extract are not recommended during pregnancy or breastfeeding. The facts note berberine may cross the placenta and has been linked to newborn harm, and can pass into breast milk.

For banaba, there isn't enough safety data to recommend use during either pregnancy or lactation. Chromium in supplement doses beyond what's in a prenatal vitamin should be avoided in pregnancy unless your doctor advises it; food amounts are fine.

Cinnamon bark extract in food amounts is likely safe during pregnancy, but high-dose supplements should be avoided. Most common side effects from these ingredients include digestive upset (nausea, diarrhea, constipation, abdominal pain), dizziness, headache, and tremor.

Berberine is generally well tolerated short-term but carries the most side-effect potential. Long-term safety of banaba extract isn't well established.

High-dose or long-term chromium use may carry risks for some people, and very high doses of cinnamon over extended periods raise concern for liver damage due to its coumarin content.

Side effects, ingredient by ingredient Banaba Cassia Cinnamon Chromium Berberine

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 4 of the 4 matched ingredients can interact with medications — Chromium, Cassia Cinnamon, Banaba, Berberine.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 1,351 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before taking GlucoGold with Berberine if you're on cyclosporine (Major concern), or on drugs that lower blood pressure, blood sugar, or are broken down by your liver's CYP3A4, CYP2D6, or CYP2C9 enzymes (Moderate). Also flag levothyroxine (thyroid hormone), blood thinners or antiplatelet drugs (including aspirin and NSAIDs), and CNS depressants like sedatives.

Your pharmacist can search your exact medications using the tool on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This product is marketed for blood sugar support and contains ingredients with some clinical evidence, especially berberine and chromium. However, it's a significant interactor — most critically with cyclosporine, and broadly with drugs metabolized by your liver, blood thinners, and diabetes medications.

If you take any prescription drugs or have diabetes, you must check your medications against the tool on this page before starting. Avoid during pregnancy and breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about GlucoGold with Berberine, straight from the product label.

Brand Doctors' Preferred
Barcode (UPC) 810047391296
Net contents 90 Tablet(s)
Market status On market
Date entered into DSLD Aug 22, 2024
DSLD ID 309891
Product type Other Combinations
Supplement form Tablet Or Pill
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for GlucoGold with Berberine by Doctors' Preferred, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Tablet(s)
Maximum serving Sizes:
3 Tablet(s)
Servings per container
90
UPC/BARCODE
810047391296
IngredientAmount% DV
Banaba leaf extract16 mg--
Cinnamon Bark Extract67 mg--
Chromium133 mcg380%
BerberPure500 mg--

Other ingredients: Croscarmellose Sodium, Microcrystalline Cellulose, Dicalcium Phosphate, Silica, Cellulose, Hypromellose, Stearic Acid, Glycerin, Hydroxypropyl Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Formulated by Julian Whitaker, MD Pioneer and trusted authority of integrative medicine whose 40+ years treating patients - with a particular focus on healthy blood sugar-and work with supplement leader Healthy Directions led to the development GlucoGold- a comprehensive formula that supports healthy blood sugar and insulin sensitivity.

Due to the nature of those ingredients, color variation may occur. Healthy support for levels already within the normal range.

Gluten Free

Unconditionally guaranteed for purity and labeled potency.

Precautions

Precautions: Consult a health care practitioner before use if you are on insulin, are hypoglycemic, are pregnant or nursing, have a serious medical condition, or use any other medication.

Keep out of reach of children.

Brand IP Statement(s)

Crominex 3+, Capros and PrimaVie are registered trademarks of Natreon, Inc. BerberPure is a registered trademark of Healthy Directions.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Doctor Developed

Doctor Formulated Doctor Formulated

Seals/Symbols

Triple Tested CGMP Certified Facility

Formula

GlucoGold with Berberine featuring 1,500 mg per day of BerberPure Berberine, plus cinnamon, banaba leaf, and Crominex 3+

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Doctor's suggested use: Take 3 tablets daily-1 before each meal.

Storage

To preserve quality and freshness, store bottle with cap tightly closed in a cool, dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

GlucoGold with Berberine by Doctors' Preferred label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

GlucoGold with Berberine label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in GlucoGold with Berberine by Doctors' Preferred

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Tablet(s) Dosage formTablet Or Pill Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Banaba leaf extract

Interacts with
299 drugs
16 mg per serving

Banaba is a leaf extract most often used to help support healthy blood sugar, and small early studies suggest its active compound corosolic acid may m...

Banaba leaf extract monograph & interactions

Cinnamon Bark Extract

Interacts with
442 drugs
67 mg per serving Form: Cinnamomum cassia Bark Extract

Cassia cinnamon is the common, inexpensive cinnamon used in cooking, and it is also taken as a supplement, most often for blood sugar support. The evi...

Cinnamon Bark Extract monograph & interactions

Chromium

Interacts with
178 drugs
133 mcg per serving Form: Crominex 3+

Chromium is an essential trace mineral involved in how the body handles sugar and fat. Some studies suggest it may modestly help blood sugar control i...

Chromium monograph & interactions

BerberPure

Interacts with
1,160 drugs
500 mg per serving Form: Berberine Hydrochloride

Berberine is a yellow plant compound that has shown promise for lowering blood sugar and cholesterol in some studies, but the quality of research vari...

BerberPure monograph & interactions

Other (inactive) ingredients: Croscarmellose Sodium, Microcrystalline Cellulose, Dicalcium Phosphate, Silica, Cellulose, Hypromellose, Stearic Acid, Glycerin, Hydroxypropyl Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

GlucoGold with Berberine by Doctors' Preferred Drug Interactions

Want to check YOUR meds against GlucoGold with Berberine?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,350Drugs
1 Major 1,330 Moderate 19 Minor

Ingredients driving the most interactions

BerberPure 1,160
Cinnamon Bark Extract 442
Banaba leaf extract 299
Chromium 178

Individual Drug Interactions

The ingredients in GlucoGold with Berberine interact with 1,350 drugs. Click any drug to see the details.

4 of the 4 ingredients in GlucoGold with Berberine interact with drugs. Each result below shows which ingredient is responsible. BerberPure Cinnamon Bark Extract Banaba leaf extract Chromium

Each ingredient & the kinds of drugs it affects

For each ingredient in GlucoGold with Berberine with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

BerberPure15 drug types · 1,160 drugs

Cyclosporine (Neoral, Sandimmune)

Berberine can increase serum levels of cyclosporine.
Berberine can reduce metabolism and increase serum levels of cyclosporine. Berberine might inhibit cytochrome P450 3A4 (CYP3A4), which metabolizes cyclosporine.

Likelihood Probable Evidence A
Anticoagulant/Antiplatelet Drugs

Theoretically, berberine might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
In vitro and in vivo research suggest that berberine can inhibit platelet aggregation. Theoretically, berberine might have additive effects when used with anticoagulant and antiplatelet drugs and increase the risk of bleeding.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, berberine may increase the risk of hypoglycemia when taken with antidiabetes drugs.
Clinical research shows that berberine may lower blood glucose levels. Theoretically, berberine might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, berberine might have additive effects with antihypertensive drugs.
Animal research suggests that berberine can have hypotensive effects. Also, a clinical study suggests that taking berberine in combination with amlodipine can lower systolic and diastolic blood pressure when compared with amlodipine alone.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, berberine might increase the sedative effects of CNS depressants.
Animal research suggests that berberine may have sedative effects. Theoretically, use of berberine along with CNS depressants might produce additive therapeutic and adverse effects.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, berberine might increase serum levels of drugs metabolized by CYP2C9.
Preliminary clinical research shows that berberine can inhibit CYP2C9. Theoretically, taking berberine with drugs metabolized by CYP2C9 might increase drug levels and increase the risk of adverse effects.

Likelihood Possible Evidence B
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, berberine might increase serum levels of drugs metabolized by CYP2D6.
In vitro research and preliminary clinical evidence show that berberine can inhibit CYP2D6. Theoretically, use of berberine with drugs metabolized by CYP2D6 might increase drug levels and increase the risk of adverse effects.

Likelihood Possible Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, berberine might increase serum levels of drugs metabolized by CYP3A4.
In vitro research and preliminary clinical research show that berberine moderately inhibits CYP3A4. Theoretically, use of berberine with drugs metabolized by CYP3A4 might increase drug levels and increase the risk of adverse effects.

Likelihood Possible Evidence A
Dextromethorphan (Robitussin Dm, Others)

Theoretically, berberine may increase serum levels of dextromethorphan.
Preliminary clinical research shows that berberine can inhibit cytochrome P450 2D6 (CYP2D6) activity and reduce the metabolism of dextromethorphan. This may increase the effects and side effects of dextromethorphan.

Likelihood Possible Evidence B
Losartan (Cozaar)

Berberine might reduce the therapeutic effects of losartan by decreasing its conversion to its active form.
Preliminary clinical research suggests that berberine can inhibit cytochrome P450 2C9 (CYP2C9) activity and reduce metabolism of losartan.

Likelihood Possible Evidence B
Metformin (Glucophage)

Theoretically, berberine might increase the therapeutic and adverse effects of metformin.
In vitro and animal studies show that berberine can increase the systemic exposure and half-life of metformin, potentially increasing metformin's effects and side effects. This interaction seems to be most apparent when berberine is administered 2 hours prior to metformin. Taking berberine and metformin at the same time does not appear to increase systemic exposure to metformin.

Likelihood Possible Evidence D
Midazolam (Versed)

Berberine can reduce metabolism of midazolam, which might increase the risk of severe adverse effects.
Preliminary clinical research shows that berberine can inhibit cytochrome P450 3A4 (CYP3A4) activity and reduce metabolism of midazolam.

Likelihood Possible Evidence B
Pentobarbital (Nembutal)

Berberine might increase the sedative effect of pentobarbital.
Evidence from animal research shows that berberine can prolong pentobarbital-induced sleeping time. Theoretically, combining berberine and pentobarbital might increase the sedative effects of pentobarbital.

Likelihood Possible Evidence D
Tacrolimus (Prograf)

Berberine has been associated with increased blood levels of tacrolimus.
In a 16-year-old patient with idiopathic nephrotic syndrome who was being treated with tacrolimus 6.5 mg twice daily, intake of berberine 200 mg three times daily increased the blood concentration of tacrolimus from 8 to 22 ng/mL. Following a reduction of the tacrolimus dose to 3 mg daily, blood levels of tacrolimus decreased to 12 ng/mL.

Likelihood Possible Evidence D
Acetazolamide

Laboratory studies and initial clinical findings suggest that berberine has the potential to increase acetazolamide concentrations in the body. More research is needed to confirm this interaction.

Likelihood Possible Evidence C
BerberPure full monograph & interactions

Cinnamon Bark Extract2 drug types · 442 drugs

Antidiabetes Drugs

Theoretically, cassia cinnamon may have additive effects with antidiabetes drugs.
Cassia cinnamon may lower blood glucose levels, and have additive effects in patients treated with antidiabetic agents. Dose adjustments to diabetes medications might be necessary.

Likelihood Possible Evidence B
Hepatotoxic Drugs

Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
There is some concern that ingesting large amounts of cassia cinnamon for an extended duration might cause hepatotoxicity in some people. Cassia cinnamon contains coumarin, which can cause hepatotoxicity in animal models. In humans, very high doses of coumarin from 50-7000 mg/day can result in hepatotoxicity that resolves when coumarin use is discontinued. Lower amounts might also cause liver problems in sensitive people, such as those with liver disease or those taking potentially hepatotoxic agents.

Likelihood Possible Evidence D
Cinnamon Bark Extract full monograph & interactions

Banaba leaf extract3 drug types · 299 drugs

Antidiabetes Drugs

Theoretically, concomitant use of banaba and hypoglycemic drugs might have additive effects.
Human and animal research suggests that banaba can lower blood glucose levels.

Likelihood Probable Evidence B
Antihypertensive Drugs

Theoretically, concomitant use of banaba and antihypertensive drugs might cause additive effects.
Human and animal research suggests that banaba can lower blood pressure.

Likelihood Probable Evidence B
Organic Anion-Transporting Polypeptide Substrates (Oatp)

Theoretically, concomitant use of banaba with substrates of OATP might reduce the bioavailability of the OATP substrate.
In vitro research shows that banaba inhibits OATP, particularly OATP2B1. OATPs are expressed in the small intestine and liver and are responsible for the absorption of drugs and other compounds.

Likelihood Possible Evidence D
Banaba leaf extract full monograph & interactions

Chromium5 drug types · 178 drugs

Antidiabetes Drugs

Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Some research shows that taking chromium might lower blood glucose levels, especially in patients with poorly controlled type 2 diabetes.

Likelihood Possible Evidence A
Insulin

Theoretically, concomitant use of chromium and insulin might increase the risk of hypoglycemia.
In clinical research, chromium has been shown to increase insulin sensitivity,

Likelihood Possible Evidence B
Levothyroxine (Synthroid, Others)

Chromium might bind levothyroxine in the intestinal tract and decrease levothyroxine absorption.
Clinical research in healthy volunteers shows that taking chromium picolinate 1000 mcg with levothyroxine 1 mg decreases serum levels of levothyroxine by 17% when compared to taking levothyroxine alone. Advise patients to take levothyroxine at least 30 minutes before or 3-4 hours after taking chromium.

Likelihood Probable Evidence B
Aspirin

Theoretically, aspirin might increase chromium absorption.
Animal research suggests that aspirin may increase chromium absorption and chromium levels in the blood.

Likelihood Possible Evidence D
Nonsteroidal Anti-Inflammatory Drugs (Nsaids)

NSAIDs might increase chromium levels in the body.
Drugs that are prostaglandin inhibitors, such as NSAIDs, seem to increase chromium absorption and retention.

Likelihood Possible Evidence D
Chromium full monograph & interactions
The maker

Brand information

Manufacturer and brand details for GlucoGold with Berberine, from the product label.

Doctors' Preferred

See all Doctors' Preferred products
Name
Healthy Directions
City
Bethesda
State
MD
ZipCode
20817
Phone Number
1-800-304-1709
Web Address
DoctorsPreferred.com
Pharmacist Counseling Corner

GlucoGold with Berberine by Doctors' Preferred: Common Questions

Does GlucoGold with Berberine by Doctors' Preferred interact with any medications?
Yes. Based on its ingredients, GlucoGold with Berberine has a known interaction with 1,350 medications, including 1 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
GlucoGold with Berberine contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm pregnant or breastfeeding?
No. Berberine should be avoided — it may cross the placenta and has been linked to newborn harm, and it passes into breast milk. Banaba leaf extract also lacks enough safety data for pregnancy and nursing. Talk to your obstetrician before considering any blood sugar supplement in pregnancy.
Is berberine the same as cinnamon?
No, they're different. Berberine is an alkaloid (a plant compound) that's been extracted and concentrated; cinnamon bark extract comes from the spice. Both are in this product and both may lower blood sugar, but berberine carries more interactions with medications.
What does chromium do?
Chromium is a trace mineral that research suggests may help your body use insulin more effectively and may lower blood glucose levels, especially in people with poorly controlled type 2 diabetes. It's rated Possibly Effective for diabetes but Possibly Ineffective for prediabetes based on current evidence.
What are the most common side effects I might notice?
Digestive upset is most common — nausea, diarrhea, constipation, abdominal pain, or bloating. Dizziness, headache, and tremor have also been reported. Start with a lower dose if you're new to berberine-containing products.
Does this product work for type 2 diabetes?
Berberine and chromium are both rated Possibly Effective for diabetes in clinical research. Banaba and cinnamon lack sufficient reliable evidence to rate. This product isn't a substitute for prescribed diabetes medication — it's intended as a supplement alongside your doctor's plan.
Can I take this with my blood pressure or diabetes medications?
Maybe, but you need to check first. All four ingredients can lower blood sugar and/or blood pressure, creating a risk of levels dropping too far. Use the medication checker on this page with your exact prescriptions, and ask your pharmacist whether dose adjustments are needed.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if GlucoGold with Berberine is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

GlucoGold with Berberine label
Go deeper

The Full Monographs Behind GlucoGold with Berberine’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Banaba

Interacts with 299 drugs

Banaba is a leaf extract most often used to help support healthy blood sugar, and small early studies suggest its active compound corosolic acid may modestly lower glucose. The overall evide...

Read the full Banaba monograph → Herb & supplement monograph

Cassia Cinnamon

Interacts with 442 drugs

Cassia cinnamon is the common, inexpensive cinnamon used in cooking, and it is also taken as a supplement, most often for blood sugar support. The evidence for its health benefits is mixed a...

Read the full Cassia Cinnamon monograph → Herb & supplement monograph

Chromium

Interacts with 178 drugs

Chromium is an essential trace mineral involved in how the body handles sugar and fat. Some studies suggest it may modestly help blood sugar control in certain people with type 2 diabetes, b...

Read the full Chromium monograph → Herb & supplement monograph

Berberine

Interacts with 1,160 drugs

Berberine is a yellow plant compound that has shown promise for lowering blood sugar and cholesterol in some studies, but the quality of research varies and it is not a replacement for presc...

Read the full Berberine monograph →
Sources

Sources & How We Checked

GlucoGold with Berberine's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 121 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Banaba 7 references
  1. Judy WV, Hari SP, Stogsdill WW, et al. Antidiabetic activity of a standardized extract (Glucosol) from Lagerstroemia speciosa leaves in Type II diabetics. A dose-dependence study. J Ethnopharmacol 2003;87:115-7. PubMed
  2. Kakuda T, Sakane I, Takihara T, et al. Hypoglycemic effect of extracts from Lagerstroemia speciosa L. leaves in genetically diabetic KK-AY mice. Biosci Biotechnol Biochem 1996;60:204-8.
  3. Fukushima, M., Matsuyama, F., Ueda, N., Egawa, K., Takemoto, J., Kajimoto, Y., Yonaha, N., Miura, T., Kaneko, T., Nishi, Y., Mitsui, R., Fujita, Y., Yamada, Y., and Seino, Y. Effect of corosolic acid on postchallenge plasma glucose levels. Diabetes Res C PubMed
  4. Yamaguchi, Y., Yamada, K., Yoshikawa, N., Nakamura, K., Haginaka, J., and Kunitomo, M. Corosolic acid prevents oxidative stress, inflammation and hypertension in SHR/NDmcr-cp rats, a model of metabolic syndrome. Life Sci 11-25-2006;79(26):2474-2479. PubMed
  5. Fuchikami H, Satoh H, Tsujimoto M, Ohdo S, Ohtani H, Sawada Y. Effects of herbal extracts on the function of human organic anion-transporting polypeptide OATP-B. Drug Metab Dispos 2006;34:577-82. PubMed
  6. Manaf A, Tjandrawinata RR, Malinda D. Insulin sensitizer in prediabetes: a clinical study with DLBS3233, a combined bioactive fraction of Cinnamomum burmanii and Lagerstroemia speciosa. Drug Des Devel Ther. 2016;10:1279-89. PubMed
  7. Tjokroprawiro A, Murtiwi S, Tjandrawinata RR. DLBS3233, a combined bioactive fraction of Cinnamomum burmanii and Lagerstroemia speciosa, in type-2 diabetes mellitus patients inadequately controlled by metformin and other oral antidiabetic agents. J Comple

See these in context on the Banaba monograph →

Cassia Cinnamon 20 references
  1. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  2. Khan A, Safdar M, Ali Khan M, et al. Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care 2003;26:3215-8. PubMed
  3. De Benito V, Alzaga R. Occupational allergic contact dermatitis from cassia (Chinese cinnamon) as a flavouring agent in coffee. Contact Dermatitis 1999;40:165. PubMed
  4. Drake TE, Maibach HI. Allergic contact dermatitis and stomatitis caused by a cinnamic aldehyde-flavored toothpaste. Arch Dermatol 1976;112:202-3.
  5. Press release. Cinnamon capsules to reduce blood sugar are medicinal products! Efficacy has not been scientifically proven - some products contain high levels of coumarin. Federal Institute of Risk Assessment (BfM), Germany, November 11, 2006. Available a
  6. Felter SP, Vassallo JD, Carlton BD, Daston GP. A safety assessment of coumarin taking into account species-specificity of toxicokinetics. Food Chem Toxicol 2006;44:462-75. PubMed
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Berberine 41 references
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