Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Hair, Skin & Nails Ingredients & Drug Interactions

by Hyalogic Beauty from Within

Hair, Skin & Nails label
See full label image
Lozenge Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Hair, Skin & Nails against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Hair, Skin & Nails is a dietary supplement by Hyalogic Beauty from Within with 5 active ingredients. Its ingredients are commonly taken for hair, skin, and nail health, bone health and osteoporosis, joint and connective tissue support.Based on those ingredients, 294 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are N-Acetylcysteine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Hair, Skin & Nails by Hyalogic Beauty from Within

Ask about any prescription or over-the-counter medication and we check it for interactions with Hair, Skin & Nails by Hyalogic Beauty from Within — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Hair, Skin & Nails by Hyalogic Beauty from Within

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 5 of its 5 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This lozenge contains five active ingredients. Silica (a form of silicon) is included for bone health and potentially for hair loss, though evidence for hair loss is limited.

Biotin supports the production and metabolism of your hair, skin, and nails; it's well established for treating biotin deficiency. Methionine is an amino acid your body uses to build proteins, including those in hair and skin.

Hyaluronic acid is a compound that holds water in skin and tissues, helping with hydration and elasticity. N-acetylcysteine (NAC) is an amino acid derivative that acts as an antioxidant and supports your body's natural detoxification pathways.

The inactive ingredients are sorbitol, natural berry flavoring, isomalt, citric acid, vegetable magnesium stearate, and stevia extract — these are fillers, flavor, and sweeteners that help form and flavor the lozenge.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: support skin, hair and nail health.
  • We looked for evidence on: Aging skin, Brittle nails, Biotin deficiency, Dry eye, hair thinning, connective tissue health — and 1 related terms.
  • The strongest evidence on file: Biotin is rated "Likely Effective" for Biotin deficiency (Natural Medicines).
  • Also on file: Hyaluronic Acid is rated "Possibly Effective" for Dry eye.
  • Also on file: Methionine is rated "Insufficient Reliable Evidence To Rate" for Wound healing.

Biotin is the ingredient with the strongest evidence here — it's established as effective for biotin deficiency. Silica is possibly effective for bone health (osteoporosis), but evidence for hair loss is insufficient.

Hyaluronic acid is possibly effective for dry eye and venous leg ulcers; evidence for aging skin is insufficient. Methionine is possibly effective for preventing neural tube birth defects in pregnancy.

N-acetylcysteine is effective for acetaminophen poisoning, atelectasis (collapsed lung tissue), and bronchial procedures, and possibly effective for bronchitis — but these are clinical uses, not the cosmetic benefits this product markets. The evidence we hold does not establish that this combination works for hair, skin, or nails specifically.

The evidence, ingredient by ingredient Silicon Biotin Methionine Hyaluronic Acid N-acetyl Cysteine (nac)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

The ingredients in this product are generally well tolerated at typical supplement doses. Silica is well tolerated from food and water, but long-term safety at high doses has not been well studied.

Biotin is safe even at fairly high doses because excess is removed in the urine; only very high doses have rarely caused mild diarrhea. Methionine is well tolerated in food amounts, but high-dose supplements may cause side effects like dizziness, drowsiness, and low blood pressure, so medical guidance is advised.

Hyaluronic acid appears well tolerated orally and topically. N-acetylcysteine is generally well tolerated at typical doses, though diarrhea, dry mouth, nausea, and vomiting can occur; more serious effects are rare and typically happen at very high doses (over 9 grams in a single dose or over 30 grams daily).

For pregnancy and breastfeeding: silica, biotin, and methionine are rated likely safe. Hyaluronic acid data is insufficient — there isn't enough information to know either way, so discuss it with your doctor.

N-acetylcysteine is rated possibly safe in pregnancy, but caution is advised for breastfeeding due to limited safety information.

Side effects, ingredient by ingredient Silicon Biotin Methionine Hyaluronic Acid N-acetyl Cysteine (nac)

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 5 matched ingredients can interact with medications — N-acetyl Cysteine (nac).
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 294 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take nitroglycerin (a heart medication), do not use this product without your doctor's approval — the risk of severe low blood pressure and severe headaches is major. Also double-check before using this if you take blood pressure medications, blood thinners (anticoagulants or antiplatelet drugs), antimalarial medication like chloroquine, or activated charcoal, as N-acetylcysteine may affect how these work.

For all other medications, no interactions are documented in the data we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This product may appeal to you if you're looking to support hair, skin, and nail health with biotin and amino acids, but evidence specifically for those cosmetic uses is limited. If you take nitroglycerin, blood pressure medication, blood thinners, or antimalarial drugs, check with your doctor or pharmacist before starting — N-acetylcysteine can interact with these.

For pregnancy or breastfeeding use, discuss it with your healthcare provider first. Overall, talk it over with your own doctor or pharmacist to make sure it fits your health picture.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Hair, Skin & Nails, straight from the product label.

Brand Hyalogic Beauty from Within
Barcode (UPC) 858259000551
Net contents 30 Lozenge(s)
Market status On market
Date entered into DSLD Apr 25, 2019
DSLD ID 201483
Product type Other Combinations
Supplement form Lozenge
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Hair, Skin & Nails by Hyalogic Beauty from Within, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Lozenge(s)
Maximum serving Sizes:
1 Lozenge(s)
Servings per container
30
UPC/BARCODE
858259000551
IngredientAmount% DV
Silica25 mg--
Biotin5000 mcg1667%
Methionine15 mg--
Hyaluronic Acid10 mg--
N-Acetylcysteine20 mg--

Other ingredients: Sorbitol, Natural Berry flavoring, Isomalt, Citric Acid, Vegetable Magnesium Stearate, Stevia extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Hyalogic's HA Collagen Builder enhances beauty from within by orally delivering key nutrients that support your body's natural collagen generation. Collagen is essential for beautiful skin, gorgeous hair and healthy nails.

Supports Healthy Hair, Skin & Nails

High molecular weight

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take one lozenge daily or as needed. Chew lozenge or hold in mouth until dissolved.

Precautions

Warnings: Consult your physician prior to using this product if you are pregnant, nursing, taking medication or have a medical condition.

Tamper resistant. Do not use if seal is broken.

Keep out of reach of children.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

2015 Hyalogic, Inc. All rights reserved. Hyalogic, HA Collagen Builder are trademarks of Hyalogic, Inc.

Formula

Hyaluronic Acid, Biotin & Silica

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

No Artificial Ingredients

Vegan Friendly

Gluten Free

Formulation

No Artificial Ingredients

Vegan Friendly

Gluten Free

General

REV 120617

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Hair, Skin & Nails by Hyalogic Beauty from Within label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Hair, Skin & Nails label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Hair, Skin & Nails by Hyalogic Beauty from Within

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Lozenge(s) Dosage formLozenge Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Silica

No known
interactions
25 mg per serving

Silicon is a trace mineral found in the body and in foods like oats, barley, and certain fruits and vegetables, and it is popular in supplements for h...

Silica monograph & interactions

Biotin

No known
interactions
5000 mcg per serving

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get...

Biotin monograph & interactions

Methionine

No known
interactions
15 mg per serving

Methionine is an essential amino acid that your body needs for protein building and many basic chemical reactions. Most people get enough from a norma...

Methionine monograph & interactions

Hyaluronic Acid

No known
interactions
10 mg per serving

Hyaluronic acid is a natural substance in the body that helps hold water in the skin, joints, and eyes. Oral and topical products are popular for skin...

Hyaluronic Acid monograph & interactions

N-Acetylcysteine

Interacts with
294 drugs
20 mg per serving

N-acetyl cysteine (NAC) is a supplement form of the amino acid cysteine and a building block for the antioxidant glutathione. It has well-established...

N-Acetylcysteine monograph & interactions

Other (inactive) ingredients: Sorbitol, Natural Berry flavoring, Isomalt, Citric Acid, Vegetable Magnesium Stearate, Stevia extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Hair, Skin & Nails by Hyalogic Beauty from Within Drug Interactions

Want to check YOUR meds against Hair, Skin & Nails?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
294Drugs
1 Major 293 Moderate

Ingredients driving the most interactions

N-Acetylcysteine 294

Individual Drug Interactions

The ingredients in Hair, Skin & Nails interact with 294 drugs. Click any drug to see the details.

1 of the 5 ingredients in Hair, Skin & Nails interact with drugs. Each result below shows which ingredient is responsible. N-Acetylcysteine

Each ingredient & the kinds of drugs it affects

For each ingredient in Hair, Skin & Nails with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

N-Acetylcysteine5 drug types · 294 drugs

Nitroglycerin

N-acetyl cysteine can increase the risk for hypotension and headaches when taken with intravenous or transdermal nitroglycerin.
Clinical research shows that concomitant administration of N-acetyl cysteine and intravenous or transdermal nitroglycerin can cause severe hypotension and intolerable headaches. Furthermore, in vitro research suggests that N-acetyl cysteine increases the anticoagulant activity of nitroglycerin.

Likelihood Probable Evidence B
Activated Charcoal

N-acetyl cysteine might reduce the effects of activated charcoal, while activated charcoal might reduce the absorption of N-acetyl cysteine.
N-acetyl cysteine appears to reduce the capacity of activated charcoal to adsorb acetaminophen and salicylic acid. Conversely, although clinical research suggests that although activated charcoal can reduce the absorption of N-acetyl cysteine by up to 40%, it does not seem to reduce its clinical effects. Other clinical evidence suggests that activated charcoal does not affect the absorption of N-acetyl cysteine.

Likelihood Possible Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, N-acetyl cysteine might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Clinical research suggests that intravenous N-acetyl cysteine decreases prothrombin time, prolongs coagulation time, decreases platelet aggregation, and increases blood loss in surgical patients. Furthermore, in vitro research suggests that N-acetyl cysteine increases the anticoagulant activity of nitroglycerin.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, N-acetyl cysteine might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research suggests that N-acetyl cysteine potentiates the hypotensive effects of the angiotensin-converting enzyme inhibitors (ACEIs) captopril and enalaprilat. Theoretically, combining N-acetyl cysteine with other antihypertensive drugs might increase the risk of hypotension.

Likelihood Possible Evidence D
Chloroquine (Aralen)

Theoretically, N-acetyl cysteine might interfere with the antimalarial effects of chloroquine.
Animal research suggests that N-acetyl cysteine might reduce the antimalarial effects of chloroquine by increasing cellular levels of glutathione.

Likelihood Possible Evidence D
N-Acetylcysteine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Hair, Skin & Nails, from the product label.

Hyalogic Beauty from Within

See all Hyalogic Beauty from Within products
Name
Hyalogic
Street Address
610 NW Platte Valley Dr.
City
Riverside
State
MO
ZipCode
64150
Phone Number
866-318-8484
Web Address
www.hyalogic.com
Pharmacist Counseling Corner

Hair, Skin & Nails by Hyalogic Beauty from Within: Common Questions

Does Hair, Skin & Nails by Hyalogic Beauty from Within interact with any medications?
Yes. Based on its ingredients, Hair, Skin & Nails has a known interaction with 294 medications, including 1 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Hair, Skin & Nails contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this actually help hair and nails grow?
Biotin in this product is well established for treating biotin deficiency, and both biotin and methionine are amino acids your body needs for healthy hair, skin, and nails. However, the evidence we hold does not specifically prove this combination works for hair growth or stronger nails in people who don't have a deficiency. Results vary by person.
Is it safe to take if I'm pregnant?
Silica, biotin, and methionine are rated likely safe in pregnancy. Hyaluronic acid has insufficient safety data — we don't have enough information to know either way. N-acetylcysteine is rated possibly safe but cautious. Talk it over with your doctor before taking any supplement in pregnancy.
Can I take this if I'm breastfeeding?
Biotin is likely safe while breastfeeding. Silica, methionine, and hyaluronic acid have limited or insufficient safety data for breastfeeding — discuss them with your doctor. N-acetylcysteine safety while breastfeeding is not well studied, so caution is advised. Check with your doctor or pharmacist first.
What's N-acetylcysteine in here for?
N-acetylcysteine (NAC) is an amino acid that acts as an antioxidant and supports your body's natural detoxification. In this beauty formula, it's included to support skin health, though it's clinically proven for acetaminophen poisoning and respiratory conditions.
Will this interact with my blood pressure medication?
N-acetylcysteine in this product may increase the effect of blood pressure medications, raising the risk of low blood pressure. Check with your doctor or pharmacist before taking this product with any blood pressure drug.
Is biotin safe at high doses?
Biotin is generally considered safe even at fairly high doses because your body removes excess in the urine. Only rarely has very high-dose biotin caused mild diarrhea. That said, if you're taking high-dose biotin supplements, check with your doctor first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Hair, Skin & Nails is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Hair, Skin & Nails label
Go deeper

The Full Monographs Behind Hair, Skin & Nails’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Silicon

Silicon is a trace mineral found in the body and in foods like oats, barley, and certain fruits and vegetables, and it is popular in supplements for hair, skin, nail, and bone health. Some s...

Read the full Silicon monograph → Herb & supplement monograph

Biotin

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get plenty from a normal diet, and true defi...

Read the full Biotin monograph → Herb & supplement monograph

Methionine

Methionine is an essential amino acid that your body needs for protein building and many basic chemical reactions. Most people get enough from a normal diet, and supplements are generally no...

Read the full Methionine monograph → Herb & supplement monograph

Hyaluronic Acid

Hyaluronic acid is a natural substance in the body that helps hold water in the skin, joints, and eyes. Oral and topical products are popular for skin moisture and joint comfort, and the evi...

Read the full Hyaluronic Acid monograph → Herb & supplement monograph

N-acetyl Cysteine (nac)

Interacts with 294 drugs

N-acetyl cysteine (NAC) is a supplement form of the amino acid cysteine and a building block for the antioxidant glutathione. It has well-established prescription uses for acetaminophen over...

Read the full N-acetyl Cysteine (nac) monograph →
Sources

Sources & How We Checked

Hair, Skin & Nails's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 125 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Silicon 19 references
  1. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  2. Jugdaohsingh R, Anderson SH, Tucker KL, et al. Dietary silicon intake and absorption. Am J Clin Nutr 2002;75:887-93. PubMed
  3. Ichiyanagi O, Sasagawa I, Adachi Y, et al. Silica urolithiasis without magnesium trisilicate intake. Urol Int 1998;61:39-42. PubMed
  4. Levison DA, Crocker PR, Banim S, Wallace DM. Silica stones in the urinary bladder. Lancet 1982;1:704-5. PubMed
  5. Lee MH, Lee YH, Hsu TH, et al. Silica stone--development due to long time oral trisilicate intake. Scand J Urol Nephrol 1993;27:267-9. PubMed
  6. Cruz Guerra, N. A., Gomez Garcia, M. A., Lovaco, Castellano F., Saez Garrido, J. C., Garcia, Cuerpo E., and Escudero, Barrilero A. [Silica urolithiasis: report of a new case]. Actas Urol.Esp 2000;24(2):202-204.
  7. Merget, R., Bauer, T., Kupper, H. U., Philippou, S., Bauer, H. D., Breitstadt, R., and Bruening, T. Health hazards due to the inhalation of amorphous silica. Arch Toxicol. 2002;75(11-12):625-634. PubMed
  8. Khuder, S. A., Peshimam, A. Z., and Agraharam, S. Environmental risk factors for rheumatoid arthritis. Rev Environ Health 2002;17(4):307-315. PubMed
  9. McLaughlin, J. K., Chow, W. H., and Levy, L. S. Amorphous silica: a review of health effects from inhalation exposure with particular reference to cancer. J Toxicol.Environ Health 4-25-1997;50(6):553-566. DOI
  10. Pelucchi, C., Pira, E., Piolatto, G., Coggiola, M., Carta, P., and La, Vecchia C. Occupational silica exposure and lung cancer risk: a review of epidemiological studies 1996-2005. Ann.Oncol. 2006;17(7):1039-1050. PubMed
  11. Gillissen, A., Gessner, C., Hammerschmidt, S., Hoheisel, G., and Wirtz, H. [Health significance of inhaled particles]. Dtsch.Med Wochenschr. 3-24-2006;131(12):639-644.
  12. Hu, J. F., Qu, H., and Wang, J. Z. [Meta analysis for relationship between exposure of free silicon dioxide and lung tumor]. Zhonghua Lao.Dong.Wei Sheng Zhi.Ye.Bing.Za Zhi. 2006;24(7):415-417.
  13. Jugdaohsingh, R. Silicon and bone health. J Nutr Health Aging 2007;11(2):99-110.
  14. Lacasse, Y., Martin, S., Gagne, D., and Lakhal, L. Dose-response meta-analysis of silica and lung cancer. Cancer Causes Control 2009;20(6):925-933. PubMed
  15. McCormic, Z. D., Khuder, S. S., Aryal, B. K., Ames, A. L., and Khuder, S. A. Occupational silica exposure as a risk factor for scleroderma: a meta-analysis. Int Arch Occup.Environ Health 2010;83(7):763-769. PubMed
  16. Haddad, F. S. and Kouyoumdjian, A. Silica stones in humans. Urol.Int 1986;41(1):70-76. PubMed
  17. Tervaert, J. W., Stegeman, C. A., and Kallenberg, C. G. Silicon exposure and vasculitis. Curr Opin.Rheumatol 1998;10(1):12-17. PubMed
  18. Steenland, K. and Stayner, L. Silica, asbestos, man-made mineral fibers, and cancer. Cancer Causes Control 1997;8(3):491-503. PubMed
  19. Boqué N, Valls RM, Pedret A, Puiggrós F, Arola L, Solà R. Relative absorption of silicon from different formulations of dietary supplements: a pilot randomized, double-blind, crossover post-prandial study. Sci Rep 2021;11(1):16479. PubMed

See these in context on the Silicon monograph →

Biotin 4 references
  1. Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Mock DM, Quirk JG, Mock NI. Marginal biotin deficiency during normal pregnancy. Am J Clin Nutr 2002;75:295-9. PubMed
  4. Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, et al. High doses of biotin in chronic progressive multiple sclerosis: a pilot study.Mult Scler Relat Disord. 2015;4(2):159-69. doi: 10.1016/j.msard.2015.01.005. PubMed

See these in context on the Biotin monograph →

Methionine 12 references
  1. La Vecchia C, Negri E, Franceschi S, Decarli A. Case-control study on influence of methionine, nitrite, and salt on gastric carcinogenesis in northern Italy. Nutr Cancer 1997;27:65-8. PubMed
  2. Btaiche IF, Khalidi N. Parenteral nutrition-associated liver complications in children. Pharmacotherapy 2002;22:188-211.. PubMed
  3. Cottington EM, LaMantia C, Stabler SP, et al. Adverse event associated with methionine loading test: a case report. Arterioscler Thromb Vasc Biol 2002;22:1046-50.. PubMed
  4. Anon. Should methionine be added to paracetamol formulations? Drug Ther Perspect 1997;10:11-3. DOI
  5. Smulders, Y. M., Rakic, M., Slaats, E. H., Treskes, M., Sijbrands, E. J., Odekerken, D. A., Stehouwer, C. D., and Silberbusch, J. Fasting and post-methionine homocysteine levels in NIDDM. Determinants and correlations with retinopathy, albuminuria, and c
  6. McAuley, D. F., Hanratty, C. G., McGurk, C., Nugent, A. G., and Johnston, G. D. Effect of methionine supplementation on endothelial function, plasma homocysteine, and lipid peroxidation. J.Toxicol.Clin.Toxicol. 1999;37(4):435-440. PubMed
  7. Hanratty, C. G., McGrath, L. T., McAuley, D. F., Young, I. S., and Johnston, G. D. The effects of oral methionine and homocysteine on endothelial function. Heart 2001;85(3):326-330. PubMed
  8. Ward, M., McNulty, H., McPartlin, J., Strain, J. J., Weir, D. G., and Scott, J. M. Effect of supplemental methionine on plasma homocysteine concentrations in healthy men: a preliminary study. Int.J.Vitam.Nutr.Res. 2001;71(1):82-86. PubMed
  9. Yaghmai, R., Kashani, A. H., Geraghty, M. T., Okoh, J., Pomper, M., Tangerman, A., Wagner, C., Stabler, S. P., Allen, R. H., Mudd, S. H., and Braverman, N. Progressive cerebral edema associated with high methionine levels and betaine therapy in a patient
  10. Talukdar R, Murthy HV, Reddy DN. Role of methionine containing antioxidant combination in the management of pain in chronic pancreatitis: a systematic review and meta-analysis. Pancreatology 2015;15(2):136-44. PubMed
  11. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids. Washington, DC: The National Academies Press, 2005. Available at: https://doi.org/10.17226 DOI
  12. Khairan P, Sobue T, Eshak ES, et al. Association of B Vitamins and Methionine Intake with the Risk of Gastric Cancer: The Japan Public Health Center-based Prospective Study. Cancer Prev Res (Phila) 2022;15(2):101-110. PubMed

See these in context on the Methionine monograph →

Hyaluronic Acid 4 references
  1. Park Y, Song JS, Choi CY, Yoon KC, Lee HK, Kim HS. A randomized multicenter study comparing 0.1%, 0.15%, and 0.3% sodium hyaluronate with 0.05% cyclosporine in the treatment of dry eye. J Ocul Pharmacol Ther. 2017;33(2):66-72. PubMed
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See these in context on the Hyaluronic Acid monograph →

N-acetyl Cysteine (nac) 86 references
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See these in context on the N-acetyl Cysteine (nac) monograph →

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