Interactions on record — worth a quick check against your medications. Based on 3 of 5 ingredients. Check your meds →
Dietary supplement

HA Gummy Berry Flavor Ingredients & Drug Interactions

by Hyalogic Beauty from Within

Gummy Or Jelly Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

HA Gummy Berry Flavor is a dietary supplement by Hyalogic Beauty from Within with 5 active ingredients. Its ingredients are commonly taken for replacing fluids and electrolytes, preventing dehydration during exercise or illness, treating low blood sodium (under medical care).Based on those ingredients, 2,035 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, Sodium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of HA Gummy Berry Flavor by Hyalogic Beauty from Within

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 2 of its 3 active ingredients.

This gummy contains 2 active ingredients: sodium and hyaluronic acid. Sodium is a mineral your body needs in small amounts for nerve and muscle function, but this product adds it on top of what you get from food.

Hyaluronic acid is a substance naturally found in your skin and joints that holds water and may help with skin moisture and eye comfort. The rest is inactive ingredients—rice syrup, cane sugar, water, vegetable oil, carnauba wax, gelatin, citric acid, natural flavor, natural color, and pectin—which are the gummy base and flavorings.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: healthy skin, hair, and collagen support.
  • We looked for evidence on: Aging skin, Wound healing, Dry eye, skin elasticity, joint comfort, connective tissue health.
  • The strongest evidence on file: Hyaluronic Acid is rated "Possibly Effective" for Dry eye (Natural Medicines).
  • Also on file: Hyaluronic Acid is rated "Insufficient Reliable Evidence To Rate" for Aging skin, Wound healing.

For sodium itself, the data shows it's likely effective for cystic fibrosis and possibly effective for preventing kidney damage from amphotericin B (a strong antifungal). For other uses listed—bipolar disorder and heart failure—there isn't enough evidence to rate it.

Hyaluronic acid is possibly effective for dry eye and venous leg ulcers (slow-healing wounds in the leg), but for aging skin, hay fever, and sexual dysfunction, the evidence is insufficient. This product is a gummy meant to be taken by mouth, so the oral evidence is what matters here.

The evidence, ingredient by ingredient Sodium Black Psyllium Hyaluronic Acid

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Sodium is well tolerated when you keep to normal dietary amounts—up to 2.3 grams per day. The safety notes are clear: normal salt in food is fine, but avoid sodium supplements or very high intake without talking to your doctor first.

High sodium is linked to high blood pressure, heart strain, and worsening kidney disease. Low sodium, conversely, may raise the risk of weak bones.

Population studies also suggest very high sodium intake may be tied to stomach cancer risk. Hyaluronic acid taken by mouth appears well tolerated, but the product's safety notes flag that long-term safety of oral supplements hasn't been fully studied, and some recommend avoiding oral supplements unless your doctor okays it.

The pregnancy and lactation data for sodium is mixed—rated likely safe in pregnancy but possibly unsafe in lactation—and no pregnancy or lactation data is on file for hyaluronic acid. Talk with your doctor or pharmacist about whether this product fits your personal situation.

Side effects, ingredient by ingredient Sodium Black Psyllium Hyaluronic Acid

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Black Psyllium, Sodium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: heart-rhythm medications; lithium.
  • For scale: 2,036 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take blood pressure medications (antihypertensives), lithium, corticosteroids, didanosine, sodium phosphate bowel prep, tolvaptan, or any other sodium-containing drugs. Sodium can change how these work or increase the risk of high blood sodium.

Your own healthcare provider can tell you whether it's safe to add this gummy alongside your medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product adds sodium on top of what you eat, which is the main consideration. If you take blood pressure medications, lithium, corticosteroids, or other sodium-sensitive drugs, you'll need to clear this with your doctor or pharmacist first.

If your diet is already high in salt or you have heart or kidney issues, your healthcare provider should weigh in. Talk it over with your own doctor before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about HA Gummy Berry Flavor, straight from the product label.

Brand Hyalogic Beauty from Within
Net contents 60 Gummy(ies)
Market status On market
Date entered into DSLD Oct 24, 2022
DSLD ID 276551
Product type Non-nutrient/non-botanical
Supplement form Gummy Or Jelly
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for HA Gummy Berry Flavor by Hyalogic Beauty from Within, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Gummie(s)
Maximum serving Sizes:
1 Gummie(s)
Servings per container
60
IngredientAmount% DV
Calories10 Calorie(s)--
Total Carbohydrates4 Gram(s)2%
Sugar2 Gram(s)--
Protein1 Gram(s)--
Saturated Fat1 Gram(s)5%
Sodium2 mg--
Trans Fat0 Gram(s)--
Total Fat1 Gram(s)2%
Dietary Fiber0 Gram(s)--
Hyaluronic Acid60 mg--

Other ingredients: organic Rice syrup, Cane Sugar, Water, Vegetable Oil, Carnauba Wax, Gelatin, Citric Acid, Natural flavor, Natural color, Pectin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Hyaluronic Acid in the body Scalp tissue & hair follicles Shaft & follicle Skin & collagen Epidermis Lips Connective tissue Replenish & hydrate the whole body with HA Gummies: Healthy skin & lips Healthy hair & scalp Healthy collagen Healthy skin elasticity

No artificial ingredients Gluten free

High molecular weight

Supports healthy skin & collagen

Brand IP Statement(s)

Beauty from within

2017 Hyalogic, Inc. All right reserved. Hyalogic and HA Gummy are trademarks of Hyalogic, Inc.

Formula

Hyaluronic Acid

Berry flavor gummies

The HA Gummy makes getting the benefits of Hyaluronic Acid (HA) simple, delicious and, well...fun! After all, a nutritional supplement cannot help you unless you take it. Naturally flavored and lightly sweetened, each HA Gummy delivers 60 mg of high molecular weight HA. Best of all, it tastes so good, taking it feels like a treat!

Why supplement with HA? Hyalogic's Beauty From Within HA Gummy contains 60 mg of HA and is designed to work from the inside out, replenishing and hydrating the skin. Hyaluronic Acid is a remarkable, water-loving molecule naturally found throughout the body. This great tasting gummy is an essential part of your beauty routine, providing a natural glow starting from within. The unique formula helps promote vibrant hair, healthy nails and glowing skin. As we age, the HA content in our bodies naturally decreases and the collagen loses elasticity, causing wrinkles and sagging skin.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, adults consume 1 gummy daily or as needed. For best results, chew slowly and thoroughly prior to swallowing.

For more intensive support, increase your daily amount to 120 mg (2 gummies per day) Servings per container, Amount per day, Amount of HA 60, 1 Gummy, 60 mg 30, 2 Gummies, 120 mg

Precautions

Warning: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.

Tamper-resistant. Do not use if seal is broken.

Keep out of reach of children.

Storage

Store in a cool, dry place. Avoid excessive heat exposure.

General Statements

Easy. Effective. Great Tasting.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

HA Gummy Berry Flavor by Hyalogic Beauty from Within label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in HA Gummy Berry Flavor by Hyalogic Beauty from Within

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Gummie(s) Dosage formGummy Or Jelly Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

2 Gram(s) per serving

Protein

1 Gram(s) per serving

Sodium

Interacts with
205 drugs
2 mg per serving

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...

Sodium monograph & interactions

Dietary Fiber

Interacts with
2,025 drugs
0 Gram(s) per serving

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...

Dietary Fiber monograph & interactions

Hyaluronic Acid

No known
interactions
60 mg per serving

Hyaluronic acid is a natural substance in the body that helps hold water in the skin, joints, and eyes. Oral and topical products are popular for skin...

Hyaluronic Acid monograph & interactions

Other (inactive) ingredients: Organic Rice syrup, Cane Sugar, Water, Vegetable Oil, Carnauba Wax, Gelatin, Citric Acid, Natural flavor, Natural color, Pectin. These complete the product’s ingredient list but are not active constituents.

Interaction report

HA Gummy Berry Flavor by Hyalogic Beauty from Within Drug Interactions

Want to check YOUR meds against HA Gummy Berry Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
2,035Drugs
227 Moderate 1,808 Minor

Ingredients driving the most interactions

Sodium 205

Each ingredient & the kinds of drugs it affects

For each ingredient in HA Gummy Berry Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Dietary Fiber7 drug types · 2,025 drugs

Carbamazepine (Tegretol)

Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Lithium

Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Metformin (Glucophage)

Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.

Likelihood Possible Evidence D
Olanzapine (Zyprexa)

Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.

Likelihood Unlikely Evidence B
Ethinyl Estradiol

Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.

Likelihood Possible Evidence B

Sodium7 drug types · 205 drugs

Antihypertensive Drugs

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.

Likelihood Probable Evidence A
Corticosteroids

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.

Likelihood Possible Evidence D
Didanosine (Videx)

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.

Likelihood Probable Evidence C
Lithium

Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.

Likelihood Probable Evidence B
Sodium Phosphates

Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Sodium-Containing Drugs

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Tolvaptan (Samsca)

Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.

Likelihood Probable Evidence C
The maker

Brand information

Manufacturer and brand details for HA Gummy Berry Flavor, from the product label.

Hyalogic Beauty from Within

See all Hyalogic Beauty from Within products
Name
Hyalogic
Street Address
610 NW Platte Valley Dr.
City
Riverside
State
MO
ZipCode
64150
Phone Number
866-318-8484
Web Address
www.hyalogic.com
Pharmacist Counseling Corner

HA Gummy Berry Flavor by Hyalogic Beauty from Within: Common Questions

Does HA Gummy Berry Flavor by Hyalogic Beauty from Within interact with any medications?
Yes. Based on its ingredients, HA Gummy Berry Flavor has a known interaction with 2,035 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
HA Gummy Berry Flavor contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this gummy actually work for aging skin?
The evidence for hyaluronic acid and aging skin is insufficient—we don't have solid data on whether it works for that yet. It is possibly effective for dry eye and slow-healing leg wounds, but skin aging isn't well established.
Is hyaluronic acid safe to take by mouth?
Hyaluronic acid taken by mouth appears well tolerated, but the product's safety notes point out that long-term safety of oral supplements hasn't been fully studied. Some sources recommend avoiding oral supplements unless your doctor advises it. It's worth asking your pharmacist or doctor whether it's right for you.
Can I take this if I'm pregnant or nursing?
Sodium is rated likely safe in pregnancy but possibly unsafe in lactation. No pregnancy or lactation data is on file for hyaluronic acid. Since the safety picture is mixed, talk with your doctor or pharmacist about whether this product is okay for you during pregnancy or while breastfeeding.
Is this just salt, or is there more sodium in it than regular food?
This is a supplement—it adds sodium on top of what you eat in food. Normal dietary salt is fine, but the product's safety notes say to avoid sodium supplements or very high intake without medical advice, especially if you have heart, kidney, or blood pressure concerns.
What are the side effects?
Sodium is well tolerated at normal levels. Serious side effects (rare) from high sodium include worsening heart disease, high blood pressure, and kidney problems. Hyaluronic acid by mouth is also well tolerated. Topical forms may occasionally cause skin itching or irritation.
Do I need to worry about fillers or extra stuff in this gummy?
The gummy contains inactive ingredients like rice syrup, cane sugar, gelatin, and pectin—standard gummy base and flavorings. If you have allergies or dietary restrictions (gelatin is animal-derived, for example), check the full ingredient list against your needs.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if HA Gummy Berry Flavor is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

HA Gummy Berry Flavor label
Sources

Sources & How We Checked

HA Gummy Berry Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 60 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sodium 38 references
  1. Garabedian-Ruffalo SM, Ruffalo RL. Drug and nutrient interactions. Am Fam Physician 1986;33:165-74.
  2. Food and Drug Administration Science Background: Safety of Sodium Phosphates Oral Solution. September 17, 2001. Available at: http://www.fda.gov/cder/drug/safety/sodiumphospate.htm
  3. Coton T, Mallaret C, Coilliot C, Carre D, Guisset M. Severe acute ulcerated gastritis induced by salt. Presse Med 2009;38(3):499-500. PubMed
  4. Frings-Meuthen P, Buehlmeier J, Baecker N, et al. High sodium chloride intake exacerbates immobilization-induced bone resorption and protein losses. J Appl Physiol 2011;111(2):537-542. PubMed
  5. Frings-Meuthen P, Baecker N, Heer M. Low-grade metabolic acidosis may be the cause of sodium chloride-induced exaggerated bone resorption. J Bone Miner Res 2008;23(4):517-524. PubMed
  6. Alam S, Johnson AG. A meta-analysis of randomised controlled trials (RCT) among healthy normotensive and essential hypertensive elderly patients to determine the effect of high salt (NaCl) diet of blood pressure. J Hum Hypertens 1999;13(6):367-74.
  7. Boudville N, Ward S, Benaroia M, House AA. Increased sodium intake correlates with greater use of antihypertensive agents by subjects with chronic kidney disease. Am J Hypertens 2005;18(10):1300-5. PubMed
  8. Bennett WM. Drug interactions and consequences of sodium restriction. Am J Clin Nutr 1997;65(2 Suppl):678S-681S. PubMed
  9. Okusa MD, Crystal LJ. Clinical manifestations and management of acute lithium intoxication. Am J Med 1994;97(4):383-9. PubMed
  10. Food and Nutrition Board, Institute of Medicine. Dietary reference intakes for water, potassium, sodium, chloride, and sulfate. Washington, DC: National Academy Press, 2005. Available at: http://www.nap.edu/openbook.php?record_id=10925. DOI
  11. D'Elia L, Rossi G, Ippolito R, Cappuccio FP, Strazzullo P. Habitual salt intake and risk of gastric cancer: a meta-analysis of prospective studies. Clin Nutr 2012;31(4):489-98. PubMed
  12. Goldsmith SR. Hyponatremia in heart failure: time for a trial. J Card Fail 2013;19(6):398-400. PubMed
  13. Willocks L, Brettle R, Keen J, Valentine C, Pinching AJ. Formulations of didanosine (ddI) and salt overload. Lancet 1992;339(8786):190.
  14. Chen L, Zhang Z, Chen W, Whelton PK, Appel LJ. Lower Sodium Intake and Risk of Headaches: Results From the Trial of Nonpharmacologic Interventions in the Elderly. Am J Public Health. 2016;106(7):1270-5. PubMed
  15. Cook NR, Appel LJ, Whelton PK. Lower levels of sodium intake and reduced cardiovascular risk. Circulation. 2014;129(9):981-9. PubMed
  16. Cook NR, Appel LJ, Whelton PK. Sodium Intake and All-Cause Mortality Over 20 Years in the Trials of Hypertension Prevention. J Am Coll Cardiol. 2016;68(15):1609-1617. PubMed
  17. Mente A, O'Donnell M, Rangarajan S, et al. Associations of urinary sodium excretion with cardiovascular events in individuals with and without hypertension: a pooled analysis of data from four studies. Lancet. 2016;388(10043):465-75. PubMed
  18. Moosavian SP, Haghighatdoost F, Surkan PJ, Azadbakht L. Salt and obesity: a systematic review and meta-analysis of observational studies. Int J Food Sci Nutr. 2017;68(3):265-277. PubMed
  19. O'Donnell M, Mente A, Rangarajan S, et al. Urinary sodium and potassium excretion, mortality, and cardiovascular events. N Engl J Med. 2014;371(7):612-23. DOI
  20. Poggio R, Gutierrez L, Matta MG, Elorriaga N, Irazola V, Rubinstein A. Daily sodium consumption and CVD mortality in the general population: systematic review and meta-analysis of prospective studies. Public Health Nutr. 2015;18(4):695-704. PubMed
  21. Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad
  22. Mahtani KR, Heneghan C, Onakpoya I, et al. Reduced Salt Intake for Heart Failure: A Systematic Review. JAMA Intern Med. 2018 Dec 1;178(12):1693-1700. PubMed
  23. Yancy CW. Sodium Restriction in Heart Failure: Too Much Uncertainty-Do the Trials. JAMA Intern Med. 2018 Dec 1;178(12):1700-1701. PubMed
  24. He FJ, Campbell NRC, Ma Y, MacGregor GA, Cogswell ME, Cook NR. Errors in estimating usual sodium intake by the Kawasaki formula alter its relationship with mortality: implications for public health. Int J Epidemiol. 2018;47(6):1784-1795. PubMed
  25. Murthy K, Ondrey GJ, Malkani N, et al. THE EFFECTS OF HYPONATREMIA ON BONE DENSITY AND FRACTURES: A SYSTEMATIC REVIEW AND META-ANALYSIS. Endocr Pract. 2019;25(4):366-378. PubMed
  26. Messerli FH, Hofstetter L, Syrogiannouli L, et al. Sodium intake, life expectancy, and all-cause mortality. Eur Heart J 2021;42(21):2103-2112. PubMed
  27. Graudal NA, Hubeck-Graudal T, Jurgens G. Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride. Cochrane Database Syst Rev 2020;12(12):CD004022. PubMed
  28. Giatti S, Santos RB, Aielo AN, et al. Association of sodium with obstructive sleep apnea. The ELSA-Brasil study. Ann Am Thorac Soc 2021;18(3):502-510. PubMed
  29. Nan X, Lu H, Wu J, et al. The interactive association between sodium intake, alcohol consumption and hypertension among elderly in northern China: a cross-sectional study. BMC Geriatr 2021;21(1):135. PubMed
  30. Kyozuka H, Fukusda T, Murata T, et al. Impact of preconception sodium intake on hypertensive disorders of pregnancy: The Japan Environment and Children's study. Pregnancy Hypertens 2021;23:66-72. PubMed
  31. Zhao L, Ogden CL, Yang Q, et al. Association of usual sodium intake with obesity among US children and adolescents, NHANES 2009-2016. Obesity (Silver Spring) 2021;29(3):587-594. PubMed
  32. Ma Y, He FJ, Sun Q, et al. 24-Hour urinary sodium and potassium excretion and cardiovascular risk. N Engl J Med 2022;386(3):252-263. PubMed
  33. Liu J, Yang X, Zhang P, et al. Association of urinary sodium excretion and left ventricular hypertrophy in people with type 2 diabetes mellitus: A cross-sectional study. Front Endocrinol (Lausanne) 2021;12:728493. PubMed
  34. Filippini T, Malavolti M, Whelton PK, Vinceti M. Sodium intake and risk of hypertension: A systematic review and dose-response meta-analysis of observational cohort studies. Curr Hypertens Rep 2022;24(5):133-144. PubMed
  35. Wang DD, Li Y, Nguyen XT, et al. Dietary sodium and potassium intake and risk of non-fatal cardiovascular diseases: The million veteran program. Nutrients 2022;14(5):1121. PubMed
  36. Kwak JH, Park CH, Eun CS, et al. The associations of dietary intake of high sodium and low zinc with gastric cancer mortality: A prospective cohort study in Korea. Nutr Cancer 2022;74(10):3501-3508. PubMed
  37. George S, Maiti R, Mishra BR, Jena M, Mohapatra D. Effect of regulated add-on sodium chloride intake on stabilization of serum lithium concentration in bipolar disorder: A randomized controlled trial. Bipolar Disord 2023;25(1):66-75. PubMed
  38. Zhou TL, Schütten MTJ, Kroon AA, et al. Urinary Sodium Excretion and Salt Intake Are Not Associated With Blood Pressure Variability in a White General Population. J Am Heart Assoc 2023;12(1):e026578. PubMed

See these in context on the Sodium monograph →

Black Psyllium 18 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
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See these in context on the Black Psyllium monograph →

Hyaluronic Acid 4 references
  1. Park Y, Song JS, Choi CY, Yoon KC, Lee HK, Kim HS. A randomized multicenter study comparing 0.1%, 0.15%, and 0.3% sodium hyaluronate with 0.05% cyclosporine in the treatment of dry eye. J Ocul Pharmacol Ther. 2017;33(2):66-72. PubMed
  2. U.S. Food and Drug Administration. Do Not Use Needle-Free Devices for Injection of Dermal Fillers - FDA Safety Communication. October 8, 2021. Available at: https://www.fda.gov/medical-devices/safety-communications/do-not-use-needle-free-devices-injection
  3. Disphanurat W, Srisantithum B. Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial. J C PubMed
  4. Humbert P, Mikosinki J, Benchikhi H, Allaert FA. Efficacy and safety of a gauze pad containing hyaluronic acid in treatment of leg ulcers of venous or mixed origin: a double-blind, randomised, controlled trial. Int Wound J 2013;10(2):159-66. PubMed

See these in context on the Hyaluronic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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