Interactions on record — worth a quick check against your medications. Based on 2 of 4 ingredients. Check your meds →
Dietary supplement

Happy Tummy Ingredients & Drug Interactions

by Herbally Grounded

Happy Tummy label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Happy Tummy against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Happy Tummy is a dietary supplement by Herbally Grounded with 4 active ingredients. Its ingredients are commonly taken for digestive upset and bloating, infant colic, menstrual cramps.Based on those ingredients, 894 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Fennel, Catnip. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Happy Tummy by Herbally Grounded

Ask about any prescription or over-the-counter medication and we check it for interactions with Happy Tummy by Herbally Grounded — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Happy Tummy by Herbally Grounded

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Oct 1, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (0.80 mL) without saying how much of each component you get.

Happy Tummy is a liquid containing 3 active ingredients: fennel, catnip, and wild lettuce (the first two are part of a proprietary blend). The product also includes inactive ingredients — glycerin, deionized water, and apple cider vinegar — which serve as carriers and preservatives.

Fennel and catnip have traditional uses in herbal medicine for digestive comfort and relaxation, though the evidence for most of those uses is limited. Wild lettuce's role in this formula isn't detailed in the product information we hold.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: assists the body in healthy digestion.
  • We looked for evidence on: Colic, Constipation, Dyspepsia, Flatulence, Irritable bowel syndrome (IBS), Nausea and vomiting — and 3 related terms.
  • The closest evidence on file: Fennel is rated "Insufficient Reliable Evidence To Rate" for Constipation (Natural Medicines).
  • Also on file: Fennel is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia, Flatulence, Irritable bowel syndrome (IBS), Nausea and vomiting, and more.
  • Also on file: Catnip is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia.

The evidence for fennel in this product is mixed. It's rated possibly effective for menstrual cramps (dysmenorrhea), but for other uses — like bronchitis, anxiety, bedwetting, and cholera — the evidence is insufficient to draw conclusions.

For catnip, all the uses we have data on — amenorrhea, anxiety, tension headaches, upper respiratory infections, indigestion, and gas — are rated as having insufficient evidence. We don't have effectiveness information on file for wild lettuce in this product.

The evidence, ingredient by ingredient Fennel Catnip

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 1 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Fennel is generally well tolerated in food amounts, but this is a concentrated supplement — use caution. The most common side effects are gastrointestinal discomfort, sun sensitivity (photosensitivity), and allergic reactions in sensitive people; seizures are rare.

Catnip is generally well tolerated in tea-like amounts, though human safety data are limited. Its most common side effects are headache, malaise (a general feeling of being unwell), and vomiting; large amounts may cause stomach upset.

Because fennel has hormone-like effects, the safety data advises against it during pregnancy and breastfeeding. Catnip's safety information shows it may stimulate the uterus and should be avoided in pregnancy; there isn't enough safety information for breastfeeding, so it's best avoided then too.

Side effects, ingredient by ingredient Fennel Catnip

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Fennel, Catnip.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; lithium.
  • For scale: 895 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Happy Tummy, check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs (Moderate), birth control pills or hormone replacement therapy (Moderate), ciprofloxacin (an antibiotic) (Moderate), tamoxifen (Moderate), drugs that cause drowsiness such as sedatives or sleeping pills (Moderate from catnip), or lithium (Moderate from catnip). We could not check wild lettuce for interactions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

If you have menstrual cramps and are looking for a herbal remedy without drug interactions, fennel has some evidence behind it — but only if you don't take blood thinners, birth control, hormone therapy, ciprofloxacin, tamoxifen, or certain liver-metabolized drugs. If you take any sedating medications or lithium, talk with your doctor or pharmacist before adding catnip to your routine.

Pregnant and breastfeeding individuals should avoid both fennel and catnip. Run this product and your medications by your own doctor or pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Happy Tummy, straight from the product label.

Brand Herbally Grounded
Barcode (UPC) 705105841434
Net contents 4 Fluid Ounce(s); 118 Milliliter(s)
Market status On market
Date entered into DSLD Sep 25, 2024
DSLD ID 318521
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Vegetarian, Adult (18 - 50 Years), Kosher, Children more than 1 but less than 4
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Happy Tummy by Herbally Grounded, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.8 mL, 2.4 mL
Maximum serving Sizes:
0.8 mL, 2.4 mL
Servings per container
49
UPC/BARCODE
705105841434
IngredientAmount% DV
Calories0 Calorie(s), 5 Calorie(s)--
Proprietary Blend0.8 mL, 2.4 mL--
Fennel0 NP, 0 NP--
Catnip0 NP, 0 NP--
Carbohydrates1 Gram(s), 2 Gram(s)1%, 1%
Lettuce, Wild0 NP, 0 NP--

Other ingredients: Glycerin, Water, Deionized, Apple Cider Vinegar

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Recommended use: Adults: Take 3 dropperfuls one to three times per day as needed. 1-3 years: Take 1 dropperful one to three times per day as needed. One dropperful is one full squeeze of the dropper bulb.

Formulation

Give tummies of all sizes the nutrients they deserve with this amazing formula that assists the body in healthy digestion. Remember, what works for little stomachs will work for older ones as well. Everyone loves a Happy Tummy.

Vegetarian

FDA Statement of Identity

Herbal Supplement

FDA Disclaimer Statement

The statements on this label have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

GMP Certified High Quality Products Vegetarian

K Parve (Kosher) K-1604

Formula

K Parve (Kosher) K-1604

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Happy Tummy by Herbally Grounded label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Happy Tummy label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Happy Tummy by Herbally Grounded

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size0.8 mL Dosage formLiquid Servings per container49 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

0.8 mL per serving

Carbohydrates

1 Gram(s) per serving

Other (inactive) ingredients: Glycerin, Water, Deionized, Apple Cider Vinegar. These complete the product’s ingredient list but are not active constituents.

Interaction report

Happy Tummy by Herbally Grounded Drug Interactions

Want to check YOUR meds against Happy Tummy?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
894Drugs
894 Moderate

Ingredients driving the most interactions

Fennel 740
Catnip 248

Individual Drug Interactions

The ingredients in Happy Tummy interact with 894 drugs. Click any drug to see the details.

2 of the 4 ingredients in Happy Tummy interact with drugs. Each result below shows which ingredient is responsible. Fennel Catnip

Each ingredient & the kinds of drugs it affects

For each ingredient in Happy Tummy with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Fennel6 drug types · 740 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.

Animal research suggests that fennel oil has antithrombotic and antiplatelet effects.

Likelihood Possible Evidence D
Ciprofloxacin (Cipro)

Theoretically, fennel might decrease the levels and clinical effects of ciprofloxacin.

Animal research shows that fennel reduces ciprofloxacin bioavailability by nearly 50%, possibly due to the metal cations such as calcium, iron, and magnesium contained in fennel. This study also found that fennel increased tissue distribution and slowed elimination of ciprofloxacin.

Likelihood Probable Evidence D
Contraceptive Drugs

Theoretically, taking large amounts of fennel might decrease the effects of contraceptive drugs due to competition for estrogen receptors.

Some constituents of fennel have estrogenic activity.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.

In vitro research suggests that fennel inhibits CYP3A4 enzyme activity. This effect has not been reported in humans.

Likelihood Possible Evidence D
Estrogens

Theoretically, taking large amounts of fennel might interfere with hormone replacement therapy due to competition for estrogen receptors.

Some constituents of fennel have estrogenic activity.

Likelihood Possible Evidence D
Tamoxifen (Nolvadex)

Theoretically, taking large amounts of fennel might decrease the antiestrogenic effect of tamoxifen.

Some constituents of fennel have estrogenic activity, which may interfere with the antiestrogenic activity of tamoxifen.

Likelihood Possible Evidence D
Fennel full monograph & interactions

Catnip2 drug types · 248 drugs

Cns Depressants

Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Clinical and animal research shows that catnip has sedative properties.

Likelihood Possible Evidence D
Lithium

Theoretically, catnip might reduce excretion and increase levels of lithium.
Catnip is thought to have diuretic properties which might reduce lithium excretion. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Catnip full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Happy Tummy, from the product label.

Herbally Grounded

See all Herbally Grounded products
Name
Herbally Grounded
City
Las Vegas
State
NV
ZipCode
89102
Phone Number
1.866.676.1410
Web Address
www.herballygrounded.com
Pharmacist Counseling Corner

Happy Tummy by Herbally Grounded: Common Questions

Does Happy Tummy by Herbally Grounded interact with any medications?
Yes. Based on its ingredients, Happy Tummy has a known interaction with 894 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Happy Tummy contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Happy Tummy while pregnant or breastfeeding?
No — the safety data advises against fennel in pregnancy because it has hormone-like effects and safety isn't established, and catnip may stimulate the uterus and also lacks sufficient safety information. Talk with your doctor or pharmacist about whether this product is right for you.
What's fennel supposed to do in this product?
Fennel has been used traditionally for digestive comfort and is rated possibly effective for menstrual cramps. The evidence for its other uses — like bronchitis and anxiety — isn't strong enough yet to draw conclusions.
Are there side effects I should know about?
Fennel is generally well tolerated but may cause gastrointestinal discomfort, sun sensitivity, or allergic reactions in sensitive people; seizures are rare. Catnip usually causes headache, malaise, or vomiting, and large amounts may upset your stomach. Most people don't experience these, but they're possible.
Will Happy Tummy make me drowsy?
Catnip has sedative properties, so it may cause drowsiness or add to drowsiness if you're already taking sedating medications. If you're sensitive to sedating herbs or take sleeping pills, check with your pharmacist first.
What if I have an allergy to fennel?
Allergic reactions to fennel can range from mild (sneezing, itching) to serious (wheezing, difficulty breathing). If you've had an allergic reaction to fennel or similar plants, or if you have asthma, talk with your doctor or pharmacist before using this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Happy Tummy label
Go deeper

The Full Monographs Behind Happy Tummy’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Fennel

Interacts with 740 drugs

Fennel is a Mediterranean herb widely used as a food and spice, and traditionally taken for digestive complaints, colic, and menstrual cramps. Some small studies suggest possible benefit for...

Read the full Fennel monograph → Herb & supplement monograph

Catnip

Interacts with 248 drugs

Catnip is a mint-family herb most often used as a calming tea for sleep, anxiety, and minor digestive upset, but solid human research supporting these uses is lacking. It is generally consid...

Read the full Catnip monograph →
Sources

Sources & How We Checked

Happy Tummy's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 24 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Fennel 17 references
  1. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. Zhu M, Wong PY, Li RC. Effect of oral administration of fennel (Foeniculum vulgare) on ciprofloxacin absorption and disposition in the rat. J Pharm Pharmacol 1999;51:1391-6.
  4. Gral N, Beani JC, Bonnot D, et al. [Plasma levels of psoralens after celery ingestion]. Ann Dermatol Venereol 1993;120:599-603.
  5. Burkhard PR, Burkhardt K, Haenggeli CA, Landis T. Plant-induced seizures: reappearance of an old problem. J Neurol 1999;246:667-70. PubMed
  6. Rosti L, Nardini A, Bettinelli ME, Rosti D. Toxic effects of a herbal tea mixture in two newborns. Acta Paediatrica 1994;83:683. PubMed
  7. Cuzzolin L, Zaffani S, and Benoni G. Safety implications regarding use of phytomedicines. Eur.J Clin Pharmacol. 2006;62:37-42. PubMed
  8. Tognolini, M., Ballabeni, V., Bertoni, S., Bruni, R., Impicciatore, M., and Barocelli, E. Protective effect of Foeniculum vulgare essential oil and anethole in an experimental model of thrombosis. Pharmacol.Res 2007;56(3):254-260. PubMed
  9. Subehan, Usia, T., Iwata, H., Kadota, S., and Tezuka, Y. Mechanism-based inhibition of CYP3A4 and CYP2D6 by Indonesian medicinal plants. J Ethnopharmacol. 5-24-2006;105(3):449-455. PubMed
  10. Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianchi, A., Chiavarini, M., and Impicciatore, M. Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci. 2-23-2006;78(13):1419-1432. PubMed
  11. Subehan, Zaidi, S. F., Kadota, S., and Tezuka, Y. Inhibition on human liver cytochrome P450 3A4 by constituents of fennel (Foeniculum vulgare): identification and characterization of a mechanism-based inactivator. J Agric.Food Chem. 12-12-2007;55(25):101 PubMed
  12. LEVY, S. B. Bronchial asthma due to ingestion of fennel and fennel seed. Ann.Allergy 1948;6(4):415.
  13. Ottolenghi, A., De Chiara, A., Arrigoni, S., Terracciano, L., and De Amici, M. [Diagnosis of food allergy caused by fruit and vegetables in children with atopic dermatitis]. Pediatr Med Chir 1995;17(6):525-530.
  14. Trabace L, Tucci P, Ciuffreda L, et al. "Natural" relief of pregnancy-related symptoms and neonatal outcomes: above all do no harm. J Ethnopharmacol. 2015;174:396-402. PubMed
  15. Denaxa D, Arkwright PD. Fennel as a cause of immediate hypersensitivity to toothpaste. Ann Allergy Asthma Immunol. 2020;125(1):99-100. PubMed
  16. Lee HW, Ang L, Lee MS, Alimoradi Z, Kim E. Fennel for reducing pain in primary dysmenorrhea: a systematic review and meta-analysis of randomized controlled trials. Nutrients 2020;12(11):3438. PubMed
  17. Mathew T, John SK, Javali M, Vasireddy M, Nadig R, Sarma GRK. Substance use related cluster headache: A case series. Headache 2022;62(7):908-910. PubMed

See these in context on the Fennel monograph →

Catnip 7 references
  1. Foster S, Tyler VE. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd ed., Binghamton, NY: Haworth Herbal Press, 1993.
  2. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  3. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  4. Osterhoudt KC, Lee SK, Callahan JM, Henretig FM. Catnip and the alteration of human consciousness. Vet Hum Toxicol 1997;39:373-5.
  5. Sherry, C. J. and Hunter, P. S. The effect of an ethanol extract of catnip (Nepeta cataria) on the behavior of the young chick. Experientia 2-15-1979;35(2):237-238. PubMed
  6. Harney, J. W., Barofsky, I. M., and Leary, J. D. Behavioral and toxicological studies of cyclopentanoid monoterpenes from Nepeta cataria. Lloydia. 1978;41(4):367-374.
  7. Massoco, C. O., Silva, M. R., Gorniak, S. L., Spinosa, M. S., and Bernardi, M. M. Behavioral effects of acute and long-term administration of catnip (Nepeta cataria) in mice. Vet.Hum.Toxicol 1995;37(6):530-533.

See these in context on the Catnip monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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