Hemp CBD Tincture Peppermint 25 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Hemp CBD Tincture Peppermint 25 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Hemp CBD Tincture Peppermint 25 mg is a dietary supplement by RE: Botanicals with 1 active ingredient. Its ingredients are commonly taken for plant-based protein source, heart health support, skin and hair health.Based on those ingredients, 938 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Hemp Aerial Parts Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Hemp CBD Tincture Peppermint 25 mg by RE: Botanicals
Ask about any prescription or over-the-counter medication and we check it for interactions with Hemp CBD Tincture Peppermint 25 mg by RE: Botanicals — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Hemp CBD Tincture Peppermint 25 mg by RE: Botanicals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This tincture contains one active ingredient: hemp aerial parts extract, which includes cannabinoids and other plant compounds from the hemp plant. The extract is suspended in medium chain triglyceride oil and flavored with peppermint oil.
Does it work?
Couldn't assess
We don't have established evidence that hemp extract works reliably for constipation, eczema, or high cholesterol — the data rates all three as having insufficient reliable evidence. The facts don't show effectiveness for other uses either.
If you're considering this for a specific health concern, talk it over with your doctor or pharmacist.
How safe is it?
Well-documented data
Hemp seed foods in normal amounts are generally well tolerated. However, concentrated extracts like this one are less studied, so caution is advised with long-term use.
Serious side effects are rare but have been reported, including allergic reactions (hives, facial swelling, shortness of breath, anaphylaxis in a small number of cases) and rare heart rhythm problems. One case of elevated liver enzymes and hepatitis appeared in a young child given very high doses of hemp extract for seizures — this is not typical use.
There is no pregnancy and lactation safety data on file for this ingredient. Talk with your doctor or pharmacist about whether it's right for you if you're pregnant or breastfeeding.
Meds to double-check
Moderate interaction found
If you take estrogen or hormone therapy, blood pressure medications, blood thinners or antiplatelet drugs, or ACE inhibitors, double-check this product with your pharmacist — hemp may change how these work. Additionally, if you take any medication cleared by your liver (ask your pharmacist), hemp might lower its levels.
No interactions are documented for the inactive ingredients we could check.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This hemp extract tincture may appeal to you if you're exploring cannabinoid products, but the effectiveness for common claims like constipation or cholesterol isn't established yet. If you take hormone therapy, blood pressure medications, blood thinners, or any drug metabolized by your liver, clear this product with your own doctor or pharmacist first — the interaction potential is real.
Concentrated hemp extracts are less studied than whole food hemp, so talk it over before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 20, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Hemp CBD Tincture Peppermint 25 mg, straight from the product label.
| Brand | RE: Botanicals |
|---|---|
| Barcode (UPC) | 854265008086 |
| Net contents | 1 Fluid Ounce(s); 30 mL |
| Market status | On market |
| Date entered into DSLD | Jun 20, 2024 |
| DSLD ID | 307056 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Organic |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Hemp CBD Tincture Peppermint 25 mg by RE: Botanicals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 10 Calorie(s) | -- |
| Calories from Fat | 10 Calorie(s) | -- |
| Total Fat | 1 Gram(s) | 2% |
| Saturated Fat | 1 Gram(s) | 5% |
| Hemp Aerial Parts Extract | 25 mg | -- |
Other ingredients: Medium Chain Triglyceride Oil, Peppermint oil
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
1% For Regenerative Agriculture
Organic, U.S.-grown full spectrum hemp
USDA Organic
Full Spectrum
Certified Organic by Pro-Cert
Formula
Organic, U.S.-grown full spectrum hemp
25mg CBD/Serving
Storage
Storage: keep in cool, dry place, away from light.
Precautions
Warning: consult your physician before use if you are pregnant, lactating, have a medical condition, or are taking any medication.
Keep out of reach of children.
Contains coconut
Seals/Symbols
USDA Organic
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Suggested use: take drop(s) directly or dilute in small amount of water or juice to drink.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Hemp CBD Tincture Peppermint 25 mg by RE: Botanicals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Hemp CBD Tincture Peppermint 25 mg by RE: Botanicals
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.
Hemp Aerial Parts Extract
Interacts with938 drugs
Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for...
Hemp Aerial Parts Extract monograph & interactionsOther (inactive) ingredients: Medium Chain Triglyceride Oil, Peppermint oil. These complete the product’s ingredient list but are not active constituents.
Hemp CBD Tincture Peppermint 25 mg by RE: Botanicals Drug Interactions
HelloPharmacist Interaction Report
RE: Botanicals Hemp CBD Tincture Peppermint 25 mg contains hemp extract, which interacts with several medication types.
The most serious documented interaction is with estrogens (hormone therapies) — hemp may theoretically interfere with how your body handles estrogen, affecting your treatment's effectiveness.
Read the full breakdown — every affected drug type, severity by severity
Hemp also has minor interactions with blood pressure medications (antihypertensives and ACE inhibitors), where additive effects could lower your blood pressure further. It may thin your blood slightly when combined with blood thinners or antiplatelet drugs (like aspirin), though human data is limited.
Additionally, hemp induces two liver enzymes (CYP1A2 and CYP3A4) that clear many medications — it could reduce the levels and effects of drugs metabolized by these pathways.
Altogether, these interactions span 939 individual medications. Check your exact prescriptions with the medication checker on this page before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Hemp CBD Tincture Peppermint 25 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Hemp CBD Tincture Peppermint 25 mg interact with 938 drugs. Click any drug to see the details.
1 of the 1 ingredient in Hemp CBD Tincture Peppermint 25 mg interact with drugs. Each result below shows which ingredient is responsible. Hemp Aerial Parts Extract
Acetaminophen, Dextromethorphan, PseudoephedrineAlka-Seltzer PLUS Flu Liquid Gels, Non Aspirin Cold Caps, Tylenol Cold, Tylenol Flu Daytime Ex Strength, Tylenol Flu Ex Strength
How Acetaminophen, Dextromethorphan, Pseudoephedrine interacts with Hemp CBD Tincture Peppermint 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Aerial Parts Extract + Acetaminophen, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Dichloralantipyrine, IsomethepteneAmidrine, Midchlor, Migquin, Migratine
How Acetaminophen, Dichloralantipyrine, Isometheptene interacts with Hemp CBD Tincture Peppermint 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Aerial Parts Extract + Acetaminophen, Dichloralantipyrine, Isometheptene interactionAcetaminophen, Dichloralphenazone, IsomethepteneMidrin
How Acetaminophen, Dichloralphenazone, Isometheptene interacts with Hemp CBD Tincture Peppermint 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Aerial Parts Extract + Acetaminophen, Dichloralphenazone, Isometheptene interactionAcetaminophen, Dichlorophenazone, IsometheptaneIsocom
How Acetaminophen, Dichlorophenazone, Isometheptane interacts with Hemp CBD Tincture Peppermint 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Aerial Parts Extract + Acetaminophen, Dichlorophenazone, Isometheptane interactionAcetaminophen, DiphenhydramineTylenol PM, Tylenol PM Ex Strength
How Acetaminophen, Diphenhydramine interacts with Hemp CBD Tincture Peppermint 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Aerial Parts Extract + Acetaminophen, Diphenhydramine interactionAcetaminophen, Diphenhydramine, PseudoephedrineChildren's Tylenol Allergy, Cold Control, Contac Night Allergy Relief
How Acetaminophen, Diphenhydramine, Pseudoephedrine interacts with Hemp CBD Tincture Peppermint 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Aerial Parts Extract + Acetaminophen, Diphenhydramine, Pseudoephedrine interactionAcetaminophen, Doxylamine, PseudoephedrineEx Strength Tylenol Sinus Nighttime
How Acetaminophen, Doxylamine, Pseudoephedrine interacts with Hemp CBD Tincture Peppermint 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Aerial Parts Extract + Acetaminophen, Doxylamine, Pseudoephedrine interactionAcetaminophen, HydrocodoneAnexsia, Anodynos DHC, Azdone, Co-Gesic, Doucet, Lorcet +9 more
How Acetaminophen, Hydrocodone interacts with Hemp CBD Tincture Peppermint 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Aerial Parts Extract + Acetaminophen, Hydrocodone interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Hemp CBD Tincture Peppermint 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Aerial Parts Extract + Acetaminophen, Ibuprofen interactionAcetaminophen, MeperidineDemerol APAP
How Acetaminophen, Meperidine interacts with Hemp CBD Tincture Peppermint 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Aerial Parts Extract + Acetaminophen, Meperidine interactionAcetaminophen, MethocarbamolRobaxacet
How Acetaminophen, Methocarbamol interacts with Hemp CBD Tincture Peppermint 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Aerial Parts Extract + Acetaminophen, Methocarbamol interactionAcetaminophen, OrphenadrineOrfenagesic
How Acetaminophen, Orphenadrine interacts with Hemp CBD Tincture Peppermint 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Aerial Parts Extract + Acetaminophen, Orphenadrine interactionAcetaminophen, OxycodonePercocet, Roxicet, Tylox, Xartemis XR
How Acetaminophen, Oxycodone interacts with Hemp CBD Tincture Peppermint 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Aerial Parts Extract + Acetaminophen, Oxycodone interactionAcetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with Hemp CBD Tincture Peppermint 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Aerial Parts Extract + Acetaminophen, Pamabrom, Pyrilamine interactionAcetaminophen, PentazocineTalacen
How Acetaminophen, Pentazocine interacts with Hemp CBD Tincture Peppermint 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Aerial Parts Extract + Acetaminophen, Pentazocine interactionAcetaminophen, Phenylephrine, ChlorpheniramineSuper Cold Tabs
How Acetaminophen, Phenylephrine, Chlorpheniramine interacts with Hemp CBD Tincture Peppermint 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Aerial Parts Extract + Acetaminophen, Phenylephrine, Chlorpheniramine interactionAcetaminophen, PhenylpropanolamineTetra Caps
How Acetaminophen, Phenylpropanolamine interacts with Hemp CBD Tincture Peppermint 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Aerial Parts Extract + Acetaminophen, Phenylpropanolamine interactionAcetaminophen, Phenylpropanolamine, PhenyltoloxamineSinubid
How Acetaminophen, Phenylpropanolamine, Phenyltoloxamine interacts with Hemp CBD Tincture Peppermint 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Aerial Parts Extract + Acetaminophen, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, PhenyltoloxaminePercogesic, Relagesic
How Acetaminophen, Phenyltoloxamine interacts with Hemp CBD Tincture Peppermint 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Aerial Parts Extract + Acetaminophen, Phenyltoloxamine interactionAcetaminophen, Phenyltoloxamine, SalicylamideLobac
How Acetaminophen, Phenyltoloxamine, Salicylamide interacts with Hemp CBD Tincture Peppermint 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Aerial Parts Extract + Acetaminophen, Phenyltoloxamine, Salicylamide interactionAcetaminophen, PropoxypheneDarvocet-N 100, Darvocet-N 50, E-Lor, Wygesic
How Acetaminophen, Propoxyphene interacts with Hemp CBD Tincture Peppermint 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Aerial Parts Extract + Acetaminophen, Propoxyphene interactionAcetaminophen, PseudoephedrineChildren's Tylenol Sinus, Dristan N.D., Non-Aspirin Sinus, Ornex, Ornex-Max, Sinutab +5 more
How Acetaminophen, Pseudoephedrine interacts with Hemp CBD Tincture Peppermint 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Aerial Parts Extract + Acetaminophen, Pseudoephedrine interactionAcetaminophen, Pseudoephedrine, TriprolidineActifed Plus ES
How Acetaminophen, Pseudoephedrine, Triprolidine interacts with Hemp CBD Tincture Peppermint 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Aerial Parts Extract + Acetaminophen, Pseudoephedrine, Triprolidine interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Hemp CBD Tincture Peppermint 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Aerial Parts ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
Read the full Hemp Aerial Parts Extract + Acetazolamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Hemp CBD Tincture Peppermint 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Aerial Parts ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Hemp Aerial Parts Extract + Acetylsalicylic Acid interactionAdagrasibKrazati
How Adagrasib interacts with Hemp CBD Tincture Peppermint 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Aerial Parts Extract + Adagrasib interactionAgomelatineValdoxan
How Agomelatine interacts with Hemp CBD Tincture Peppermint 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Aerial Parts ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Aerial Parts Extract + Agomelatine interactionAlfentanilAlfenta
How Alfentanil interacts with Hemp CBD Tincture Peppermint 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Aerial Parts Extract + Alfentanil interactionAlfuzosinUroxatral
How Alfuzosin interacts with Hemp CBD Tincture Peppermint 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Aerial Parts Extract + Alfuzosin interactionAliskirenTekturna
How Aliskiren interacts with Hemp CBD Tincture Peppermint 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Aerial Parts ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Antihypertensive Drugs Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Aerial Parts Extract + Aliskiren interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Hemp CBD Tincture Peppermint 25 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Hemp Aerial Parts Extract
Estrogens
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.
Ace Inhibitors (Aceis)
Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.
Anticoagulant/Antiplatelet Drugs
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.
Antihypertensive Drugs
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.
Brand information
Manufacturer and brand details for Hemp CBD Tincture Peppermint 25 mg, from the product label.
RE: Botanicals
See all RE: Botanicals products- Name
- RE Botanicals, Inc.
- City
- Boulder
- State
- CO
- ZipCode
- 80302
- Web Address
- www.REBOTANICALS.com
Hemp CBD Tincture Peppermint 25 mg by RE: Botanicals: Common Questions
Does Hemp CBD Tincture Peppermint 25 mg by RE: Botanicals interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does this product actually contain CBD?
Can I take this if I'm on birth control or hormone therapy?
What about allergies — is hemp safe if I've never had it?
Will this lower my blood pressure or interfere with my blood pressure meds?
Is this safe to take long-term?
Does this work for eczema or cholesterol?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Hemp CBD Tincture Peppermint 25 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Hemp CBD Tincture Peppermint 25 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Hemp CBD Tincture Peppermint 25 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Hemp 12 references
- Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
- Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
- Girgih AT, Alashi A, He R, Malomo S, Aluko RE. Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats. Eur J Nutr. 2014;53(5):1237-46. PubMed
- Richard MN, Ganguly R, Steigerwald SN, Al-Khalifa A, Pierce GN. Dietary hempseed reduces platelet aggregation. J Thromb Haemost. 2007;5(2):424-5. PubMed
- Stadtmauer G, Beyer K, Bardina L, Sicherer SH. Anaphylaxis to ingestion of hempseed (Cannabis sativa). J Allergy Clin Immunol. 2003;112(1):216-7. PubMed
- Del Bo' C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. PubMed
- Alkhammash S, Tsui H, Thomson DMP. Cannabis and hemp seed allergy. J Allergy Clin Immunol Pract. 2019;7(7):2429-2430.e1. PubMed
- Stokes JR, Hartel R, Ford LB, Casale TB. Cannabis (hemp) positive skin tests and respiratory symptoms. Ann Allergy Asthma Immunol. 2000;85(3):238-40. PubMed
- Déléaval M, Burri H, Bakelants E. Harmless herbs? A case report of acquired long QT syndrome and torsades de pointes in a patient taking herbal supplements. HeartRhythm Case Rep 2022;8(5):309-12. PubMed
- Singh M, Sehgal M, Yacoub M, et al. Severe liver dysfunction in a toddler receiving nonprescription phytocannabinoid. J Am Pharm Assoc (2003) 2022;62(4):1438-1440. PubMed
- Clark E, Nilsson U, Samaran Q, Raison-Peyron N. Allergic contact dermatitis from Cannabis sativa (hemp) seed oil. Contact Dermatitis 2022;87(3):292-293.
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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