High Potency Glucose Tolerance Factor GTF Chromium 200 mcg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking High Potency Glucose Tolerance Factor GTF Chromium 200 mcg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
High Potency Glucose Tolerance Factor GTF Chromium 200 mcg is a dietary supplement by Nature's Plus with 1 active ingredient. Its ingredients are commonly taken for blood sugar support in type 2 diabetes, weight loss and appetite control, insulin sensitivity.Based on those ingredients, 178 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are GTF Chromium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against High Potency Glucose Tolerance Factor GTF Chromium 200 mcg by Nature's Plus
Ask about any prescription or over-the-counter medication and we check it for interactions with High Potency Glucose Tolerance Factor GTF Chromium 200 mcg by Nature's Plus — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of High Potency Glucose Tolerance Factor GTF Chromium 200 mcg by Nature's Plus
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: GTF chromium at 200 micrograms per tablet. Chromium is an essential trace mineral that plays a role in how your body handles blood sugar and insulin.
The tablet also contains several inactive ingredients—microcrystalline cellulose, di-calcium phosphate, stearic acid, magnesium stearate, pharmaceutical glaze, and silica—that serve as binders, fillers, and coating materials.
Does it work?
Couldn't assess
The evidence for chromium varies by use. It's rated likely effective for chromium deficiency, which can occur if your diet is very low in the mineral.
For type 2 diabetes, chromium is rated possibly effective—some research suggests it may help lower blood glucose, especially in people whose diabetes isn't well controlled. However, for prediabetes (impaired glucose tolerance), schizophrenia, and high blood pressure, the evidence is rated possibly ineffective, meaning the data doesn't support its use for those conditions.
How safe is it?
Well-documented data
Chromium is generally well tolerated at typical supplement doses. The most common side effects are mild: gastrointestinal irritation, headaches, insomnia, irritability, and mood changes.
Skin reactions like rashes and hives can occur, particularly in people with a contact allergy to chromium. Serious side effects are rare but have been reported at higher doses, including kidney and liver damage and low platelet counts (thrombocytopenia).
The safety notes advise caution with high or long-term doses and recommend avoiding extra chromium supplement doses during pregnancy unless your doctor specifically recommends it, though small amounts from food or prenatal vitamins are generally considered acceptable.
Meds to double-check
Moderate interaction found
Before taking this supplement, double-check with your doctor or pharmacist if you're on insulin or antidiabetes medications (blood sugar drugs)—chromium may increase the risk of low blood sugar. Similarly, check if you take levothyroxine or other thyroid hormone replacement, as chromium can reduce how much gets absorbed.
If you regularly use NSAIDs or aspirin, mention that too, since they may increase how much chromium your body holds onto.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product may help if you have a chromium deficiency or are exploring options for type 2 diabetes management, but you'll want to check it against your medications first—especially if you take insulin, other blood sugar drugs, or thyroid hormone replacement. The evidence for prediabetes, high blood pressure, and other uses is weak.
Talk with your doctor or pharmacist about whether it fits your situation and how it interacts with your specific medications.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 1, 2012.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about High Potency Glucose Tolerance Factor GTF Chromium 200 mcg, straight from the product label.
| Brand | Nature's Plus |
|---|---|
| Barcode (UPC) | 097467034846 |
| Net contents | 90 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Oct 1, 2012 |
| DSLD ID | 13017 |
| Product type | Mineral |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for High Potency Glucose Tolerance Factor GTF Chromium 200 mcg by Nature's Plus, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| GTF Chromium | 200 mcg | 167% |
Other ingredients: Microcrystalline Cellulose, Di-Calcium Phosphate, Stearic Acid, Magnesium Stearate, Pharmaceutical Glaze, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Nutritional Support for Natural Energy Production and Overall Well-Being.*
Suggested/Recommended/Usage/Directions
DIRECTIONS: As a dietary supplement, one tablet daily or as directed by a physician.
Storage
KEEP TIGHTLY CLOSED IN A COOL, DRY PLACE.
General
PRODUCT NO. 3484 LBL. 1128415
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
GLUTEN Free
QUALITY NATURAL SUPPLEMENTS(R)
Formulation
Free from artificial colors and preservatives.
Vegetarian
Precautions
WARNING DIABETICS: This product may enhance tissue insulin sensitivity. Use only under a physician’s supervision.
KEEP OUT OF REACH OF CHILDREN.
Brand IP Statement(s)
(C)NATURAL ORGANICS(R)
The Energy Supplements(R)
FDA Disclaimer Statement
*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
High Potency Glucose Tolerance Factor GTF Chromium 200 mcg by Nature's Plus label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in High Potency Glucose Tolerance Factor GTF Chromium 200 mcg by Nature's Plus
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.
GTF Chromium
Interacts with178 drugs
Chromium is an essential trace mineral involved in how the body handles sugar and fat. Some studies suggest it may modestly help blood sugar control i...
GTF Chromium monograph & interactionsOther (inactive) ingredients: Microcrystalline Cellulose, Di-Calcium Phosphate, Stearic Acid, Magnesium Stearate, Pharmaceutical Glaze, Silica. These complete the product’s ingredient list but are not active constituents.
High Potency Glucose Tolerance Factor GTF Chromium 200 mcg by Nature's Plus Drug Interactions
HelloPharmacist Interaction Report
Nature's Plus High Potency Glucose Tolerance Factor GTF Chromium interacts with several medication types through its single active ingredient, chromium.
The most serious interaction is with insulin and antidiabetes drugs (blood sugar medications), where chromium may increase the risk of low blood sugar (hypoglycemia) by enhancing how your body uses insulin or making these drugs work harder than intended.
Read the full breakdown — every affected drug type, severity by severity
Chromium also interacts moderately with levothyroxine (thyroid hormone), a commonly prescribed medication. Chromium can bind levothyroxine in your digestive tract and reduce how much gets absorbed into your bloodstream—clinical research shows a 17% drop in levothyroxine levels when taken together.
Minor interactions occur with NSAIDs (ibuprofen, naproxen) and aspirin, which may increase how much chromium your body absorbs and retains.
Altogether, these interactions span 178 individual medications. If you take any blood sugar medication, thyroid hormone replacement, or pain relievers regularly, use the medication checker on this page to see your exact drugs before starting this supplement.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against High Potency Glucose Tolerance Factor GTF Chromium 200 mcg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in High Potency Glucose Tolerance Factor GTF Chromium 200 mcg interact with 178 drugs. Click any drug to see the details.
1 of the 1 ingredient in High Potency Glucose Tolerance Factor GTF Chromium 200 mcg interact with drugs. Each result below shows which ingredient is responsible. GTF Chromium
AcarboseGlucobay, Prandase, Precose
How Acarbose interacts with High Potency Glucose Tolerance Factor GTF Chromium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
Gtf ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Gtf Chromium + Acarbose interactionAcetohexamideDymelor
How Acetohexamide interacts with High Potency Glucose Tolerance Factor GTF Chromium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
Gtf ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Gtf Chromium + Acetohexamide interactionAlbiglutideTanzeum
How Albiglutide interacts with High Potency Glucose Tolerance Factor GTF Chromium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
Gtf ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Gtf Chromium + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with High Potency Glucose Tolerance Factor GTF Chromium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
Gtf ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Gtf Chromium + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with High Potency Glucose Tolerance Factor GTF Chromium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
Gtf ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Gtf Chromium + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with High Potency Glucose Tolerance Factor GTF Chromium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
Gtf ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Gtf Chromium + Alogliptin, Pioglitazone interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with High Potency Glucose Tolerance Factor GTF Chromium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
Gtf ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Gtf Chromium + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionCanagliflozinInvokana
How Canagliflozin interacts with High Potency Glucose Tolerance Factor GTF Chromium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
Gtf ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Gtf Chromium + Canagliflozin interactionCanagliflozin, MetforminInvokamet
How Canagliflozin, Metformin interacts with High Potency Glucose Tolerance Factor GTF Chromium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
Gtf ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Gtf Chromium + Canagliflozin, Metformin interactionCanagliflozin, Metformin HydrochlorideInvokamet XR
How Canagliflozin, Metformin Hydrochloride interacts with High Potency Glucose Tolerance Factor GTF Chromium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
Gtf ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Gtf Chromium + Canagliflozin, Metformin Hydrochloride interactionChlorpropamideChlorpropam, Diabinese
How Chlorpropamide interacts with High Potency Glucose Tolerance Factor GTF Chromium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
Gtf ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Gtf Chromium + Chlorpropamide interactionDapagliflozinFarxiga
How Dapagliflozin interacts with High Potency Glucose Tolerance Factor GTF Chromium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
Gtf ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Gtf Chromium + Dapagliflozin interactionDapagliflozin Propanediol, MetforminXigduo XR
How Dapagliflozin Propanediol, Metformin interacts with High Potency Glucose Tolerance Factor GTF Chromium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
Gtf ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Gtf Chromium + Dapagliflozin Propanediol, Metformin interactionDapagliflozin Propanediol, Saxagliptin HydrochlorideQtern
How Dapagliflozin Propanediol, Saxagliptin Hydrochloride interacts with High Potency Glucose Tolerance Factor GTF Chromium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
Gtf ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Gtf Chromium + Dapagliflozin Propanediol, Saxagliptin Hydrochloride interactionDapagliflozin, Metformin Hydrochloride, Saxagliptin HydrochlorideQternmet XR
How Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interacts with High Potency Glucose Tolerance Factor GTF Chromium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
Gtf ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Gtf Chromium + Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interactionDasiglucagon HydrochlorideZegalogue
How Dasiglucagon Hydrochloride interacts with High Potency Glucose Tolerance Factor GTF Chromium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
Gtf ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Gtf Chromium + Dasiglucagon Hydrochloride interactionDulaglutideTrulicity
How Dulaglutide interacts with High Potency Glucose Tolerance Factor GTF Chromium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
Gtf ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Gtf Chromium + Dulaglutide interactionEmpagliflozinJardiance
How Empagliflozin interacts with High Potency Glucose Tolerance Factor GTF Chromium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
Gtf ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Gtf Chromium + Empagliflozin interactionEmpagliflozin, Linagliptin, Metformin HydrochlorideTrijardy XR
How Empagliflozin, Linagliptin, Metformin Hydrochloride interacts with High Potency Glucose Tolerance Factor GTF Chromium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
Gtf ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Gtf Chromium + Empagliflozin, Linagliptin, Metformin Hydrochloride interactionEmpagliflozin, MetforminSynjardy
How Empagliflozin, Metformin interacts with High Potency Glucose Tolerance Factor GTF Chromium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
Gtf ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Gtf Chromium + Empagliflozin, Metformin interactionEmpagliflozin, Metformin HydrochlorideSynjardy XR
How Empagliflozin, Metformin Hydrochloride interacts with High Potency Glucose Tolerance Factor GTF Chromium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
Gtf ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Gtf Chromium + Empagliflozin, Metformin Hydrochloride interactionErtugliflozinSteglatro
How Ertugliflozin interacts with High Potency Glucose Tolerance Factor GTF Chromium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
Gtf ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Gtf Chromium + Ertugliflozin interactionErtugliflozin, Metformin HydrochlorideSegluromet
How Ertugliflozin, Metformin Hydrochloride interacts with High Potency Glucose Tolerance Factor GTF Chromium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
Gtf ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Gtf Chromium + Ertugliflozin, Metformin Hydrochloride interactionExenatideBydureon, Byetta
How Exenatide interacts with High Potency Glucose Tolerance Factor GTF Chromium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
Gtf ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Gtf Chromium + Exenatide interactionExenatide SyntheticBydureon BCISE
How Exenatide Synthetic interacts with High Potency Glucose Tolerance Factor GTF Chromium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
Gtf ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Gtf Chromium + Exenatide Synthetic interactionGliclazideDiamicron
How Gliclazide interacts with High Potency Glucose Tolerance Factor GTF Chromium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
Gtf ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Gtf Chromium + Gliclazide interactionGlimepirideAmaryl
How Glimepiride interacts with High Potency Glucose Tolerance Factor GTF Chromium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
Gtf ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Gtf Chromium + Glimepiride interactionGlipizideGlucotrol, Glucotrol XL
How Glipizide interacts with High Potency Glucose Tolerance Factor GTF Chromium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
Gtf ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Gtf Chromium + Glipizide interactionGlipizide, MetforminMetaglip
How Glipizide, Metformin interacts with High Potency Glucose Tolerance Factor GTF Chromium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
Gtf ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Gtf Chromium + Glipizide, Metformin interactionGlucagonBaqsimi, Glucagon
How Glucagon interacts with High Potency Glucose Tolerance Factor GTF Chromium 200 mcg — through 1 ingredient. Tap an ingredient for the detail:
Gtf ChromiumAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Read the full Gtf Chromium + Glucagon interactionEach ingredient & the kinds of drugs it affects
For each ingredient in High Potency Glucose Tolerance Factor GTF Chromium 200 mcg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
GTF Chromium
Antidiabetes Drugs
Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Some research shows that taking chromium might lower blood glucose levels, especially in patients with poorly controlled type 2 diabetes.
Insulin
Theoretically, concomitant use of chromium and insulin might increase the risk of hypoglycemia.
In clinical research, chromium has been shown to increase insulin sensitivity,
Levothyroxine (Synthroid, Others)
Chromium might bind levothyroxine in the intestinal tract and decrease levothyroxine absorption.
Clinical research in healthy volunteers shows that taking chromium picolinate 1000 mcg with levothyroxine 1 mg decreases serum levels of levothyroxine by 17% when compared to taking levothyroxine alone. Advise patients to take levothyroxine at least 30 minutes before or 3-4 hours after taking chromium.
Aspirin
Theoretically, aspirin might increase chromium absorption.
Animal research suggests that aspirin may increase chromium absorption and chromium levels in the blood.
Nonsteroidal Anti-Inflammatory Drugs (Nsaids)
NSAIDs might increase chromium levels in the body.
Drugs that are prostaglandin inhibitors, such as NSAIDs, seem to increase chromium absorption and retention.
Brand information
Manufacturer and brand details for High Potency Glucose Tolerance Factor GTF Chromium 200 mcg, from the product label.
Nature's Plus
See all Nature's Plus products- Name
- Natural Organics Laboratories, Inc. makers of Nature's Plus
- Street Address
- 9500 New Horizons Blvd.
- City
- Amityville
- State
- New York
- ZipCode
- 11701
- Web Address
- www.naturesplus.com
High Potency Glucose Tolerance Factor GTF Chromium 200 mcg by Nature's Plus: Common Questions
Does High Potency Glucose Tolerance Factor GTF Chromium 200 mcg by Nature's Plus interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is it safe to take this if I'm pregnant?
Can I take this while breastfeeding?
What side effects might I notice?
Does this actually work for blood sugar?
Why does the interaction list show so many medications?
Should I take this at a different time than my thyroid medication?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if High Potency Glucose Tolerance Factor GTF Chromium 200 mcg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind High Potency Glucose Tolerance Factor GTF Chromium 200 mcg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
High Potency Glucose Tolerance Factor GTF Chromium 200 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 53 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Chromium 53 references
- Cerulli J, Grabe DW, Gauthier I, et al. Chromium picolinate toxicity. Ann Pharmacother 1998;32:428-31. PubMed
- Urberg M, Zemel MB. Evidence for synergism between chromium and nicotinic acid in the control of glucose tolerance in elderly humans. Metabolism 1987;36:896-9. PubMed
- Mohamedshah FY, Moser-Veillon PB, Yamini S, et al. Distribution of a stable isotope of chromium (53Cr) in serum, urine, and breast milk in lactating women. Am J Clin Nutr 1998;67:1250-5. PubMed
- Wasser WG, Feldman NS, D'Agati VD. Chronic renal failure after ingestion of over-the-counter chromium picolinate. [letter]. Ann Intern Med 1997;126:410. PubMed
- Mertz W. Interaction of chromium with insulin: a progress report. Nutr Rev 1998;56:174-7. PubMed
- Anderson RA. Chromium, glucose intolerance and diabetes. J Am Coll Nutr 1998;17:548-55. PubMed
- McLeod MN, Gaynes BN, Golden RN. Chromium potentiation of antidepressant pharmacotherapy for dysthymic disorder in 5 patients. J Clin Psych 1999;60:237-40. PubMed
- Fowler JF Jr. Systemic contact dermatitis caused by oral chromium picolinate. Cutis 2000;65:116. DOI
- Trent LK, Thieding-Cancel D. Effects of chromium picolinate on body composition. J Sports Med Phys Fitness 1995;35:273-80.
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
- Rabinovitz H, Friedensohn A, Leibovitz A, et al. Effect of chromium supplementation on blood glucose and lipid levels in type 2 diabetes mellitus elderly patients. Int J Vitam Nutr Res 2004;74:178-82. PubMed
- Lanca S, Alves A, Vieira AI, et al. Chromium-induced toxic hepatitis. Eur J Intern Med 2002;13:518-20. PubMed
- Kockler DR, McCarthy MW, Lawson CL. Seizure activity and unresponsiveness after hydroxycut ingestion. Pharmacotherapy 2001;21:647-51.. PubMed
- Davidson JR, Abraham K, Connor KM, McLeod MN. Effectiveness of chromium in atypical depression: a placebo-controlled trial. Biol Psychiatry 2003;53:261-4.. PubMed
- Food Standards Agency. Medicines and Healthcare products Regulatory Agency (MHRA). Expert Group on Vitamins and Minerals. Available at: http://cot.food.gov.uk/sites/default/files/vitmin2003.pdf.
- Mouser JF, Hak EB, Helms RA, et al. Chromium and zinc concentrations in pediatric patients receiving long-term parenteral nutrition. Am J Health Syst Pharm 1999;56:1950-6. PubMed
- Stevens T, Qadri A, Zein NN. Two patients with acute liver injury associated with use of the herbal weight-loss supplement hydroxycut. Ann Intern Med 2005;142:477-8. PubMed
- Wani S, Weskamp C, Marple J, Spry L. Acute tubular necrosis associated with chromium picolinate-containing dietary supplement. Ann Pharmacother 2006;40:563-6. PubMed
- Kleefstra N, Houweling ST, Jansman FG, et al. Chromium treatment has no effect in patients with poorly controlled, insulin-treated type 2 diabetes in an obese Western population: a randomized, double-blind, placebo-controlled trial. Diabetes Care 2006;29: PubMed
- Martin J, Wang ZQ, Zhang XH, et al. Chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes. Diabetes Care 2006;29:1826-32. PubMed
- Singer GM, Geohas J. The effect of chromium picolinate and biotin supplementation on glycemic control in poorly controlled patients with type 2 diabetes mellitus: a placebo-controlled, double-blinded, randomized trial. Diabetes Technol Ther 2006;8:636-43. PubMed
- John-Kalarickal J, Pearlman G, Carlson HE. New medications which decrease levothyroxine absorption. Thyroid 2007;17:763-5. PubMed
- Yazaki Y, Faridi Z, Ma Y, et al. A pilot study of chromium picolinate for weight loss. J Altern Complement Med 2010;16:291-9. PubMed
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