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Dietary supplement

Hoodia SuperThin Ingredients & Drug Interactions

by Healthy Natural Systems

Hoodia SuperThin label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Hoodia SuperThin against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Hoodia SuperThin is a dietary supplement by Healthy Natural Systems with 1 active ingredient. Its ingredients are commonly taken for appetite suppression, weight loss, reducing food cravings.Based on those ingredients, 262 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Hoodia Gordonii cactus extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Hoodia SuperThin by Healthy Natural Systems

Ask about any prescription or over-the-counter medication and we check it for interactions with Hoodia SuperThin by Healthy Natural Systems — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Hoodia SuperThin by Healthy Natural Systems

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Hoodia SuperThin contains one active ingredient: hoodia gordonii cactus extract. This comes in a capsule filled with inactive ingredients—gelatin, microcrystalline cellulose, magnesium stearate, and silica—which serve as the capsule material and flow agents.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Hoodia's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: weight loss by controlling appetite.
  • We looked for evidence on: Obesity, Overweight, Weight management, Appetite control.
  • The closest evidence on file: Hoodia is rated "Insufficient Reliable Evidence To Rate" for Obesity (Natural Medicines).

The evidence for hoodia gordonii in treating obesity is insufficient in the data we hold. While the product is marketed for weight management, we have no reliable clinical evidence on file to support or refute that claim.

If you're considering it for weight loss, that's a conversation worth having with your doctor or pharmacist.

The evidence, ingredient by ingredient Hoodia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Hoodia has limited safety data. Reported side effects include disturbances of skin sensation, headache, dizziness, lightheadedness, and nausea.

There's also concern that it may raise blood pressure and heart rate. The product facts note side-effect and quality concerns have been reported.

During pregnancy, there isn't enough safety information—the facts advise avoiding it. The same applies to breastfeeding: insufficient data means you should avoid use unless your doctor or pharmacist advises otherwise.

Side effects, ingredient by ingredient Hoodia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Hoodia.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 262 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start Hoodia SuperThin, check your medications against these types: blood pressure drugs (antihypertensive medications), beta-blockers, diabetes medications, and insulin. All carry moderate-severity interaction potential with hoodia.

Your doctor or pharmacist can tell you whether it's safe to combine any of these with this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Hoodia SuperThin may appeal to those seeking appetite suppression, but the evidence for weight loss isn't established in our data, and side effects and safety concerns have been flagged. If you take blood pressure medications, diabetes drugs, insulin, or beta-blockers, this product is not a casual add-on—check with your doctor or pharmacist first.

Pregnant and breastfeeding people should also talk it over with their healthcare provider before considering it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Hoodia SuperThin, straight from the product label.

Brand Healthy Natural Systems
Barcode (UPC) 746888777930
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Nov 21, 2012
DSLD ID 15310
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Hoodia SuperThin by Healthy Natural Systems, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
746888777930
IngredientAmount% DV
Hoodia Gordonii cactus extract250 mg--

Other ingredients: Gelatin, Microcrystalline Cellulose, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

PERFECT BLEND OF NATURE & SCIENCE

Results may vary.

The perfect blend of Nature & Science, you will reduce your cravings and be able to say no to the excess meals and snacks without feeling deprived.*

EFFECTIVE WEIGHT LOSS SYSTEM* MAXIMIZE ANY DIET Promotes Weight Loss*

Brand IP Statement(s)

Hoodia SuperThin(TM) is a perfect natural plant based diet nutrient that supports weight loss by helping to control your appetite so you eat less calories.*

Hoodia SuperThin(TM) also naturally boosts your energy and mood, both really important when you are dieting.*

Visit: Inch BY Inch.com(TM) for more info, videos and support

HNS(TM)

Precautions

Warning: Do not use if seal is broken or missing.

Not intended for use by persons under 18.

Do not take if you are pregnant or nursing.

Suggested/Recommended/Usage/Directions

This supplement should be taken in conjunction with a healthy diet and regular exercise program.

Directions: As a dietary supplement, take 1 Hoodia SuperThin(TM) capsule prior to your morning, afternoon and evening meals. May be used with any diet plan.

FDA Statement of Identity

DIETARY SUPPLEMENT

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Storage

Store at 15-30(0)C (59-86(0)F). Protect from heat, light and moisture.

General

L-7793-3

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Hoodia SuperThin by Healthy Natural Systems label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Hoodia SuperThin label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Hoodia SuperThin by Healthy Natural Systems

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Hoodia Gordonii cactus extract

Interacts with
262 drugs
250 mg per serving

Hoodia is a succulent plant from southern Africa that is marketed as an appetite suppressant for weight loss, but solid human evidence that it actuall...

Hoodia Gordonii cactus extract monograph & interactions

Other (inactive) ingredients: Gelatin, Microcrystalline Cellulose, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Hoodia SuperThin by Healthy Natural Systems Drug Interactions

Want to check YOUR meds against Hoodia SuperThin?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
262Drugs
262 Moderate

Ingredients driving the most interactions

Hoodia Gordonii cactus extract 262

Individual Drug Interactions

The ingredients in Hoodia SuperThin interact with 262 drugs. Click any drug to see the details.

1 of the 1 ingredient in Hoodia SuperThin interact with drugs. Each result below shows which ingredient is responsible. Hoodia Gordonii cactus extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Hoodia SuperThin with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Hoodia Gordonii cactus extract4 drug types · 262 drugs

Antidiabetes Drugs

Animal research shows that a steroid glycoside of hoodia, gordonoside F, increases glucose-stimulated insulin secretion by activating GPR119. This effect enhances glucose disposal. Theoretically, concomitant use of hoodia with antidiabetes medications may enhance blood glucose-lowering effects and increase the risk of hypoglycemia. Some antidiabetes medications include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.

Likelihood Possible Evidence D
Antihypertensive Drugs

Clinical research shows that hoodia can increase blood pressure. Theoretically, concomitant use of hoodia with antihypertensive drugs might decrease the effectiveness of the antihypertensive drugs and increase the risk of hypertension. Some antihypertensive drugs include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), Amlodipine (Norvasc), hydrochlorothiazide (HydroDiuril), furosemide (Lasix), and many others.

Likelihood Possible Evidence D
Beta-Blockers

Evidence from in vitro research shows that hoodia may stimulate beta-adrenergic receptors. Also, clinical research shows that hoodia can increase blood pressure and heart rate. Theoretically, using hoodia with beta-blockers might decrease the effects of these medications. Some beta-blocker drugs include atenolol (Tenormin), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), and propranolol (Inderal).

Likelihood Possible Evidence D
Insulin

Animal research shows that a steroid glycoside of hoodia, gordonoside F, increases glucose-stimulated insulin secretion by activating GPR119. Theoretically, concomitant use of hoodia with insulin may enhance the blood glucose-lowering effects of insulin. Blood glucose levels should be monitored.

Likelihood Possible Evidence D
Hoodia Gordonii cactus extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Hoodia SuperThin, from the product label.

Healthy Natural Systems

See all Healthy Natural Systems products
Name
HEALTHY NATURAL SYSTEMS(R)
Street Address
3750 Investment Lane, Suite 2
City
West Palm Beach
State
FL
ZipCode
33404
Web Address
www.inchbyinch.com
Pharmacist Counseling Corner

Hoodia SuperThin by Healthy Natural Systems: Common Questions

Does Hoodia SuperThin by Healthy Natural Systems interact with any medications?
Yes. Based on its ingredients, Hoodia SuperThin has a known interaction with 262 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Hoodia SuperThin contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this work for weight loss?
The evidence we have on file is insufficient to say whether hoodia gordonii actually works for obesity. The product is marketed for appetite control, but reliable clinical proof isn't established in our data—that's something to discuss with your doctor.
What side effects should I watch for?
Reported side effects include disturbances of skin sensation, headache, dizziness, lightheadedness, and nausea. There's also concern that hoodia can raise blood pressure and heart rate. Limited safety data exist overall, and product quality concerns have been flagged.
Can I take this if I'm pregnant?
The facts advise against it during pregnancy. There isn't enough safety information to know whether it's okay, so talk with your doctor or pharmacist for personalized advice.
Can I take this while breastfeeding?
The facts advise against it while breastfeeding due to insufficient safety data. Check with your doctor or pharmacist to discuss your individual situation.
What's actually in this capsule?
It contains hoodia gordonii cactus extract as the active ingredient, plus gelatin, microcrystalline cellulose, magnesium stearate, and silica as inactive capsule material and binders.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Hoodia SuperThin is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Hoodia SuperThin label
Go deeper

The Full Monographs Behind Hoodia SuperThin’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Hoodia

Interacts with 262 drugs

Hoodia is a succulent plant from southern Africa that is marketed as an appetite suppressant for weight loss, but solid human evidence that it actually works is lacking. The few quality stud...

Read the full Hoodia monograph →
Sources

Sources & How We Checked

Hoodia SuperThin's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hoodia 3 references
  1. Blom WAM, Abrahamse SL, Bradford R, et al. Effects of 15-d repeated consumption of Hoodia gordonii purified extract on safety, ad libitum energy intake, and body weight in healthy, overweight women: a randomized controlled trial. Am J Clin Nutr 2011;94(5) PubMed
  2. Roza O, Lovász N, Zupkó I, Hohmann J, Csupor D. Sympathomimetic activity of a Hoodia gordonii product: a possible mechanism of cardiovascular side effects. Biomed Res Int. 2013;2013:171059.
  3. Zhang S, Ma Y, Li J, et al. Molecular matchmaking between the popular weight-loss herb Hoodia gordonii and GPR119, a potential drug target for metabolic disorder. Proc Natl Acad Sci U S A. 2014;111(40):14571-6.

See these in context on the Hoodia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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