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Dietary supplement

Hydrangea Root 335 mg Ingredients & Drug Interactions

by Dr. Clark Store

Hydrangea Root 335 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Hydrangea Root 335 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Hydrangea Root 335 mg is a dietary supplement by Dr. Clark Store with 1 active ingredient. Its ingredients are commonly taken for kidney and bladder stones, urinary tract complaints, enlarged prostate symptoms.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Hydrangea. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Hydrangea Root 335 mg by Dr. Clark Store

Ask about any prescription or over-the-counter medication and we check it for interactions with Hydrangea Root 335 mg by Dr. Clark Store — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Hydrangea Root 335 mg by Dr. Clark Store

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: 335 mg of hydrangea root per capsule. The capsule itself is made of gelatin.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: kidney and urinary tract health.
  • We looked for evidence on: kidney stones, urinary tract infections, bladder health.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

We hold no effectiveness data for hydrangea root in our records, so we can't tell you what it's intended to do or whether it works for any particular purpose.

The evidence, ingredient by ingredient Hydrangea

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Human safety data for hydrangea are limited, especially with larger or longer-term doses. Orally, hydrangea may cause gastroenteritis (stomach and intestinal upset), dizziness, and chest tightness.

The safety data advise against use during pregnancy and while breastfeeding because there isn't enough reliable information to know whether it's safe for you or your baby.

Side effects, ingredient by ingredient Hydrangea

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Hydrangea.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: lithium.
  • For scale: 1 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take lithium, check with your pharmacist or doctor before starting. The diuretic effect of hydrangea may increase lithium levels in your body.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you take lithium, you need to talk with your doctor or pharmacist before using this product—your lithium dose may need adjustment. Because human safety data are limited and pregnancy and breastfeeding safety aren't established, mention this supplement to your healthcare provider before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Hydrangea Root 335 mg, straight from the product label.

Brand Dr. Clark Store
Barcode (UPC) 652384106504
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Jun 24, 2020
DSLD ID 219966
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Hydrangea Root 335 mg by Dr. Clark Store, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
100
UPC/BARCODE
652384106504
IngredientAmount% DV
Hydrangea335 mg--

Other ingredients: Gelatin Capsules

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Adults and children 12 years of age or over, take 1 capsule daily, or as directed by a healthcare professional.

General Statements

Self Health Resource Center 1055 Bay Blvd., Ste A Chula Vista, CA 91911 Customer Service Toll Free: (866) DR-CLARK (372-5275) www.DrClarkStore.com

Leader in purity Established by Dr. Clark's family in 1993

Company does not adopt any Dr. Clark claims.

Formulation

Our products don't contain flow agents like magnesium stearate. Not now, not ever.

Kidney & urinary tract health

Seals/Symbols

Made in USA

FDA Statement of Identity

Dietary Supplement

Storage

Store at room temperature.

Precautions

Keep away from children.

Warning: If you are pregnant, nursing or taking any medications, consult your doctor before use.

If any adverse reactions occur, immediately stop using this product and consult your doctor. If seal under cap is damaged or missing, do not use.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Hydrangea Root 335 mg by Dr. Clark Store label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Hydrangea Root 335 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Hydrangea Root 335 mg by Dr. Clark Store

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Hydrangea

Interacts with
1 drug
335 mg per serving

Hydrangea root has a long history in folk medicine, mainly for urinary and kidney stone complaints, but there is very little modern human research to...

Hydrangea monograph & interactions

Other (inactive) ingredients: Gelatin Capsules. These complete the product’s ingredient list but are not active constituents.

Interaction report

Hydrangea Root 335 mg by Dr. Clark Store Drug Interactions

Want to check YOUR meds against Hydrangea Root 335 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1Drugs
1 Moderate

Ingredients driving the most interactions

Hydrangea 1

Individual Drug Interactions

The ingredients in Hydrangea Root 335 mg interact with 1 drug. Click any drug to see the details.

1 of the 1 ingredient in Hydrangea Root 335 mg interact with drugs. Each result below shows which ingredient is responsible. Hydrangea

Each ingredient & the kinds of drugs it affects

For each ingredient in Hydrangea Root 335 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Hydrangea1 drug type · 1 drug

Lithium

Hydrangea is thought to have diuretic properties. Theoretically, due to these potential diuretic effects, hydrangea might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Hydrangea full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Hydrangea Root 335 mg, from the product label.

Dr. Clark Store

See all Dr. Clark Store products
Name
Dr. Clark Store
Street Address
1055 Bay Blvd., Ste A
City
Chula Vista
State
CA
ZipCode
91911
Phone Number
(866) 372-5275
Web Address
www.DrClarkStore.com
Pharmacist Counseling Corner

Hydrangea Root 335 mg by Dr. Clark Store: Common Questions

Does Hydrangea Root 335 mg by Dr. Clark Store interact with any medications?
Yes. Based on its ingredients, Hydrangea Root 335 mg has a known interaction with 1 medication. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Hydrangea Root 335 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm pregnant?
The safety data advise against it. There isn't enough reliable information to know whether hydrangea is safe during pregnancy, so talk with your doctor before using it.
Can I take this while breastfeeding?
No—there's no reliable safety data for breastfeeding, so it's best to avoid it. If you're considering it, talk with your doctor or pharmacist.
What side effects might I experience?
Hydrangea may cause stomach and intestinal upset, dizziness, and a feeling of tightness in your chest. Because human safety data are limited, especially at larger doses or with long-term use, unexpected effects are possible.
Does this product have fillers?
The capsule is made of gelatin. There are no other inactive ingredients listed.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Hydrangea Root 335 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Hydrangea Root 335 mg label
Go deeper

The Full Monographs Behind Hydrangea Root 335 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Hydrangea

Interacts with 1 drug

Hydrangea root has a long history in folk medicine, mainly for urinary and kidney stone complaints, but there is very little modern human research to confirm it works for any condition. Beca...

Read the full Hydrangea monograph →
Sources

Sources & How We Checked

Hydrangea Root 335 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hydrangea 1 reference
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.

See these in context on the Hydrangea monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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