Immune Defense Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Immune Defense against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Immune Defense is a dietary supplement by Vibrant Health with 4 active ingredients. Its ingredients are commonly taken for immune support, cold and flu prevention, digestive and gut health.Based on those ingredients, 293 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Beta 1,3-1,6 Glucans 70% standardized extract, Larch Arabinogalactans extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Immune Defense by Vibrant Health
Ask about any prescription or over-the-counter medication and we check it for interactions with Immune Defense by Vibrant Health — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Immune Defense by Vibrant Health
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Immune Defense contains four active ingredients. Larch arabinogalactan and beta-1,3-1,6 glucans (standardized to 70%) are fiber-derived compounds traditionally used to support immune function.
IgY Max and Gigartina whole plant red marine extract round out the formula. The product also contains inactive ingredients—vegetable capsule, microcrystalline cellulose, magnesium stearate, and silicon dioxide—which serve as the capsule shell and binding agents.
Does it work?
Not established
The evidence for these ingredients is mixed. Beta-glucans show likely effectiveness for cholesterol management and heart disease support.
Larch arabinogalactan, on the other hand, has insufficient reliable evidence for common cold or cholesterol support—meaning we don't have enough good research to know if it works for those purposes. IgY Max and Gigartina lack established effectiveness ratings in our data.
How safe is it?
Well-documented data
Larch arabinogalactan is generally well tolerated as a fiber, though some people report bloating and flatulence. Long-term safety data are limited, so caution is advised.
Beta-glucans from food sources are well tolerated by most people, but concentrated supplement doses lack robust safety data—use caution and discuss with your doctor or pharmacist first. For pregnancy and lactation, there isn't enough safety data on file for either ingredient to know whether it's safe; talk with your doctor or pharmacist for personalized guidance before taking this product if you're pregnant or breastfeeding.
Meds to double-check
Moderate interaction found
Check your medications against this product if you take immunosuppressants such as azathioprine, cyclosporine, tacrolimus, or daclizumab—the larch arabinogalactan and beta-glucans here could interfere with how they work. Also double-check if you're on blood pressure medications; beta-glucans may lower blood pressure further.
Bring your medication list to your pharmacist or doctor before you start.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
This formula may appeal to people interested in immune or cardiovascular support, but it's not right for everyone. If you take immunosuppressants (after transplant, for autoimmune disease, or for certain inflammatory conditions) or blood pressure medication, you need to check with your doctor or pharmacist before adding this product.
The same goes if you're pregnant, breastfeeding, or have questions about whether it fits your health situation.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 7, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Immune Defense, straight from the product label.
| Brand | Vibrant Health |
|---|---|
| Barcode (UPC) | 074306800350 |
| Net contents | 120 Vegetable Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jan 7, 2019 |
| DSLD ID | 183055 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Immune Defense by Vibrant Health, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Larch Arabinogalactans extract | 250 mg | -- |
| Beta 1,3-1,6 Glucans 70% standardized extract | 10 mg | -- |
| IgY Max | 500 mg | -- |
| Gigartina whole plant Red Marine extract | 5 mg | -- |
Other ingredients: Vegetable Capsule, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Formula
Contains: egg
Immune Defense provides arabinogalactans, anti-viral sulfated polysaccharides, beta glucans and HyperImmune egg, a unique new ingredient that delivers 26 human-specific antibodies, inhibits microbial adhesion, fosters growth of healthy bacteria, and reduces inflammatory cytokines.
HyperImmune Egg, Beta Glucans Larch Arabinogalactans & Red Marine Algae
Precautions
Contains: egg
If you are pregnant, planning to become pregnant, breast feeding, taking any prescription medication, or have a medical condition, consult your physician or healthcare professional before taking this product.
Do not exceed recommended dosage.
Keep out of reach of children.
Brand IP Statement(s)
IgY Max is a trademark of IgY Nutrition, LLC and is used under license.
ResistAid is a trademark of Lonza Group Ltd., Basel, Switzerland
Suggested/Recommended/Usage/Directions
Directions As a dietary supplement, take from two (2) to eight (8) vegetable capsules in divided dosages each day, or as directed by a health professional.
Storage
Store in a cool dry place.
General Statements
A Comprehensive Immune Support Formula Clinically Formulated
Four Powerful Immune Boosters
Look What's Inside Full Disclosure Labeling
Made in the USA since 1992 with worldwide ingredients 2 HDPE
General
Version 2.0 ID18_17414
Formulation
Gluten free Non-GMO Soy free
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Immune Defense by Vibrant Health label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Immune Defense by Vibrant Health
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Vegetable Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Larch Arabinogalactans extract
Interacts with121 drugs
Larch arabinogalactan is a soluble fiber from larch trees that is mainly used as a prebiotic and for immune support. Early research is interesting but...
Larch Arabinogalactans extract monograph & interactionsBeta 1,3-1,6 Glucans 70% standardized extract
Interacts with293 drugs
Beta-glucans are natural fibers found in oats, barley, mushrooms, and yeast. The strongest evidence supports the oat and barley types for modestly low...
Beta 1,3-1,6 Glucans 70% standardized extract monograph & interactionsIgY Max
Gigartina whole plant Red Marine extract
Other (inactive) ingredients: Vegetable Capsule, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
Immune Defense by Vibrant Health Drug Interactions
HelloPharmacist Interaction Report
Immune Defense by Vibrant Health contains two ingredients with documented interactions: larch arabinogalactan and beta-glucans.
The most serious concern is a Moderate-severity interaction with immunosuppressant drugs (such as azathioprine, cyclosporine, tacrolimus, and others used after transplant or for autoimmune conditions). Both ingredients have immunostimulant effects that could theoretically interfere with how these medications work.
Read the full breakdown — every affected drug type, severity by severity
Beta-glucans also carry a Moderate-severity interaction with blood pressure medications (antihypertensives). Clinical research shows beta-glucans can lower blood pressure in some people, so combining them with drugs meant to do the same could increase the risk of blood pressure dropping too low.
Two other ingredients in this formula—IgY Max and Gigartina red marine extract—we could not check; no interaction data is on file for them. Altogether, these interactions span 293 individual medications.
Use the search tool below to look up your exact prescriptions before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Immune Defense?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Immune Defense interact with 293 drugs. Click any drug to see the details.
2 of the 4 ingredients in Immune Defense interact with drugs. Each result below shows which ingredient is responsible. Beta 1,3-1,6 Glucans 70% standardized extract Larch Arabinogalactans extract
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Immune Defense — through 2 ingredients. Tap an ingredient for the detail:
Beta 1,3-1,6 Glucans 70% Standardized ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Beta 1,3-1,6 Glucans 70% Standardized Extract + 6-mercaptopurine interactionLarch Arabinogalactans ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Larch Arabinogalactans Extract + 6-mercaptopurine interactionAbrocitinibCibinqo
How Abrocitinib interacts with Immune Defense — through 2 ingredients. Tap an ingredient for the detail:
Beta 1,3-1,6 Glucans 70% Standardized ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Beta 1,3-1,6 Glucans 70% Standardized Extract + Abrocitinib interactionLarch Arabinogalactans ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Larch Arabinogalactans Extract + Abrocitinib interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Immune Defense — through 1 ingredient. Tap an ingredient for the detail:
Beta 1,3-1,6 Glucans 70% Standardized ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Beta 1,3-1,6 Glucans 70% Standardized Extract + Acebutolol interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Immune Defense — through 1 ingredient. Tap an ingredient for the detail:
Beta 1,3-1,6 Glucans 70% Standardized ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Beta 1,3-1,6 Glucans 70% Standardized Extract + Acetazolamide interactionAdalimumabHumira
How Adalimumab interacts with Immune Defense — through 2 ingredients. Tap an ingredient for the detail:
Larch Arabinogalactans ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Larch Arabinogalactans Extract + Adalimumab interactionBeta 1,3-1,6 Glucans 70% Standardized ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Beta 1,3-1,6 Glucans 70% Standardized Extract + Adalimumab interactionAdalimumab-adazHyrimoz
How Adalimumab-adaz interacts with Immune Defense — through 2 ingredients. Tap an ingredient for the detail:
Beta 1,3-1,6 Glucans 70% Standardized ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Beta 1,3-1,6 Glucans 70% Standardized Extract + Adalimumab-adaz interactionLarch Arabinogalactans ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Larch Arabinogalactans Extract + Adalimumab-adaz interactionAdalimumab-adbmCyltezo
How Adalimumab-adbm interacts with Immune Defense — through 2 ingredients. Tap an ingredient for the detail:
Larch Arabinogalactans ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Larch Arabinogalactans Extract + Adalimumab-adbm interactionBeta 1,3-1,6 Glucans 70% Standardized ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Beta 1,3-1,6 Glucans 70% Standardized Extract + Adalimumab-adbm interactionAdalimumab-afzbAbrilada
How Adalimumab-afzb interacts with Immune Defense — through 2 ingredients. Tap an ingredient for the detail:
Beta 1,3-1,6 Glucans 70% Standardized ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Beta 1,3-1,6 Glucans 70% Standardized Extract + Adalimumab-afzb interactionLarch Arabinogalactans ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Larch Arabinogalactans Extract + Adalimumab-afzb interactionAdalimumab-attoAmjevita
How Adalimumab-atto interacts with Immune Defense — through 2 ingredients. Tap an ingredient for the detail:
Larch Arabinogalactans ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Larch Arabinogalactans Extract + Adalimumab-atto interactionBeta 1,3-1,6 Glucans 70% Standardized ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Beta 1,3-1,6 Glucans 70% Standardized Extract + Adalimumab-atto interactionAdalimumab-bwwdHadlima
How Adalimumab-bwwd interacts with Immune Defense — through 2 ingredients. Tap an ingredient for the detail:
Beta 1,3-1,6 Glucans 70% Standardized ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Beta 1,3-1,6 Glucans 70% Standardized Extract + Adalimumab-bwwd interactionLarch Arabinogalactans ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Larch Arabinogalactans Extract + Adalimumab-bwwd interactionAdalimumab-fkjpHulio
How Adalimumab-fkjp interacts with Immune Defense — through 2 ingredients. Tap an ingredient for the detail:
Larch Arabinogalactans ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Larch Arabinogalactans Extract + Adalimumab-fkjp interactionBeta 1,3-1,6 Glucans 70% Standardized ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Beta 1,3-1,6 Glucans 70% Standardized Extract + Adalimumab-fkjp interactionAlefaceptAmevive
How Alefacept interacts with Immune Defense — through 2 ingredients. Tap an ingredient for the detail:
Beta 1,3-1,6 Glucans 70% Standardized ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Beta 1,3-1,6 Glucans 70% Standardized Extract + Alefacept interactionLarch Arabinogalactans ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Larch Arabinogalactans Extract + Alefacept interactionAlemtuzumabCampath
How Alemtuzumab interacts with Immune Defense — through 2 ingredients. Tap an ingredient for the detail:
Larch Arabinogalactans ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Larch Arabinogalactans Extract + Alemtuzumab interactionBeta 1,3-1,6 Glucans 70% Standardized ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Beta 1,3-1,6 Glucans 70% Standardized Extract + Alemtuzumab interactionAliskirenTekturna
How Aliskiren interacts with Immune Defense — through 1 ingredient. Tap an ingredient for the detail:
Beta 1,3-1,6 Glucans 70% Standardized ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Beta 1,3-1,6 Glucans 70% Standardized Extract + Aliskiren interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Immune Defense — through 1 ingredient. Tap an ingredient for the detail:
Beta 1,3-1,6 Glucans 70% Standardized ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Beta 1,3-1,6 Glucans 70% Standardized Extract + Ambrisentan interactionAmilorideAmilamont, Midamor
How Amiloride interacts with Immune Defense — through 1 ingredient. Tap an ingredient for the detail:
Beta 1,3-1,6 Glucans 70% Standardized ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Beta 1,3-1,6 Glucans 70% Standardized Extract + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Immune Defense — through 1 ingredient. Tap an ingredient for the detail:
Beta 1,3-1,6 Glucans 70% Standardized ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Beta 1,3-1,6 Glucans 70% Standardized Extract + Amiloride, Hydrochlorothiazide interactionAmlodipineNorliqva
How Amlodipine interacts with Immune Defense — through 1 ingredient. Tap an ingredient for the detail:
Beta 1,3-1,6 Glucans 70% Standardized ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Beta 1,3-1,6 Glucans 70% Standardized Extract + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Immune Defense — through 1 ingredient. Tap an ingredient for the detail:
Beta 1,3-1,6 Glucans 70% Standardized ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Beta 1,3-1,6 Glucans 70% Standardized Extract + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Immune Defense — through 1 ingredient. Tap an ingredient for the detail:
Beta 1,3-1,6 Glucans 70% Standardized ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Beta 1,3-1,6 Glucans 70% Standardized Extract + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Immune Defense — through 1 ingredient. Tap an ingredient for the detail:
Beta 1,3-1,6 Glucans 70% Standardized ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Beta 1,3-1,6 Glucans 70% Standardized Extract + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Immune Defense — through 1 ingredient. Tap an ingredient for the detail:
Beta 1,3-1,6 Glucans 70% Standardized ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Beta 1,3-1,6 Glucans 70% Standardized Extract + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with Immune Defense — through 1 ingredient. Tap an ingredient for the detail:
Beta 1,3-1,6 Glucans 70% Standardized ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Beta 1,3-1,6 Glucans 70% Standardized Extract + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Immune Defense — through 1 ingredient. Tap an ingredient for the detail:
Beta 1,3-1,6 Glucans 70% Standardized ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Beta 1,3-1,6 Glucans 70% Standardized Extract + Ammonium Chloride interactionAnifrolumab-fniaSaphnelo
How Anifrolumab-fnia interacts with Immune Defense — through 2 ingredients. Tap an ingredient for the detail:
Beta 1,3-1,6 Glucans 70% Standardized ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Beta 1,3-1,6 Glucans 70% Standardized Extract + Anifrolumab-fnia interactionLarch Arabinogalactans ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Larch Arabinogalactans Extract + Anifrolumab-fnia interactionAntithymocyte GlobulinThymoglobulin
How Antithymocyte Globulin interacts with Immune Defense — through 2 ingredients. Tap an ingredient for the detail:
Larch Arabinogalactans ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Larch Arabinogalactans Extract + Antithymocyte Globulin interactionBeta 1,3-1,6 Glucans 70% Standardized ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Read the full Beta 1,3-1,6 Glucans 70% Standardized Extract + Antithymocyte Globulin interactionAprocitentanTryvio
How Aprocitentan interacts with Immune Defense — through 1 ingredient. Tap an ingredient for the detail:
Beta 1,3-1,6 Glucans 70% Standardized ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Beta 1,3-1,6 Glucans 70% Standardized Extract + Aprocitentan interactionAtenololAtenix, Tenormin
How Atenolol interacts with Immune Defense — through 1 ingredient. Tap an ingredient for the detail:
Beta 1,3-1,6 Glucans 70% Standardized ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Beta 1,3-1,6 Glucans 70% Standardized Extract + Atenolol interactionAtenolol, ChlortalidoneAtenixCo, Tenoret 50, Totaretic
How Atenolol, Chlortalidone interacts with Immune Defense — through 1 ingredient. Tap an ingredient for the detail:
Beta 1,3-1,6 Glucans 70% Standardized ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Beta 1,3-1,6 Glucans 70% Standardized Extract + Atenolol, Chlortalidone interactionAtenolol, ChlorthalidoneTenoretic
How Atenolol, Chlorthalidone interacts with Immune Defense — through 1 ingredient. Tap an ingredient for the detail:
Beta 1,3-1,6 Glucans 70% Standardized ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Read the full Beta 1,3-1,6 Glucans 70% Standardized Extract + Atenolol, Chlorthalidone interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Immune Defense with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Beta 1,3-1,6 Glucans 70% standardized extract
Antihypertensive Drugs
Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Clinical research shows that taking beta-glucans may reduce systolic and diastolic blood pressure in some hypertensive individuals.
Immunosuppressants
Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Some clinical research shows that beta-glucans have immunostimulant effects.
Larch Arabinogalactans extract
Immunosuppressants
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects. Immunosuppressant drugs include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), and other drugs.
Brand information
Manufacturer and brand details for Immune Defense, from the product label.
Vibrant Health
See all Vibrant Health products- Name
- Vibrant Health
- City
- Shelton
- State
- CT
- ZipCode
- 06484
- Phone Number
- 1-800-242-1835
- Web Address
- vibranthealth.com
Immune Defense by Vibrant Health: Common Questions
Does Immune Defense by Vibrant Health interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does this product actually help prevent colds?
Will this upset my stomach?
Is it safe to take while I'm breastfeeding?
What does beta-glucan actually do?
Can I take this if I had an organ transplant?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Immune Defense is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Immune Defense’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Larch Arabinogalactan
Interacts with 121 drugsLarch arabinogalactan is a soluble fiber from larch trees that is mainly used as a prebiotic and for immune support. Early research is interesting but limited, and most claims are not yet fi...
Read the full Larch Arabinogalactan monograph → Herb & supplement monographBeta-glucans
Interacts with 293 drugsBeta-glucans are natural fibers found in oats, barley, mushrooms, and yeast. The strongest evidence supports the oat and barley types for modestly lowering cholesterol and blood sugar, while...
Read the full Beta-glucans monograph →Sources & How We Checked
Immune Defense's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 19 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Larch Arabinogalactan 8 references
- D'Adamo P. Larch arabinogalactan. J Naturopath Med 1996;6:33-7.
- Kelly GS. Larch arabinogalactan: Clinical relevance of a novel immune-enhancing polysaccharide. Alt Med Rev 1999;4:96-103.
- Marett R, Slavin JL. No long-term benefits of supplementation with arabinogalactan on serum lipids and glucose. J Am Diet Assoc 2004;104:636-9.
- Robinson RR, Feirtag J, Slavin JL. Effects of dietary arabinogalactan on gastrointestinal and blood parameters in healthy human subjects. J Am Coll Nutr 2001;20:279-85. PubMed
- Udani JK, Singh BB, Barrett ML, Singh VJ. Proprietary arabinogalactan extract increases antibody response to the pneumonia vaccine: a randomized, double-blind, placebo-controlled, pilot study in healthy volunteers. Nutr J 2010;9:32. PubMed
- Grube B, Stier H, Riede L, Gruenwald J. Tolerability of a proprietary larch arabinogalactan extract: a randomized, double-blind, placebo-controlled clinical trial in healthy subjects. Food Nutr Sci 2012;3:1533-8. DOI
- Dion C, Chappuis E, Ripoll C. Does larch arabinogalactan enhance immune function? A review of mechanistic and clinical trials. Nutr Metab (Lond) 2016;13:28. PubMed
- Riede L, Grube B, Gruenwald J. Larch arabinogalactan effects on reducing incidence of upper respiratory tract infections. Curr Med Res Opin 2013;29(3):251-8.
See these in context on the Larch Arabinogalactan monograph →
Beta-glucans 11 references
- Katz, D. L., Nawaz, H., Boukhalil, J., Giannamore, V., Chan, W., Ahmadi, R., and Sarrel, P. M. Acute effects of oats and vitamin E on endothelial responses to ingested fat. Am.J.Prev.Med. 2001;20(2):124-129. PubMed
- Keenan, J. M., Pins, J. J., Frazel, C., Moran, A., and Turnquist, L. Oat ingestion reduces systolic and diastolic blood pressure in patients with mild or borderline hypertension: a pilot trial. J.Fam.Pract. 2002;51(4):369.
- Maki, K. C., Galant, R., Samuel, P., Tesser, J., Witchger, M. S., Ribaya-Mercado, J. D., Blumberg, J. B., and Geohas, J. Effects of consuming foods containing oat beta-glucan on blood pressure, carbohydrate metabolism and biomarkers of oxidative stress i
- Bergendiova, K., Tibenska, E., and Majtan, J. Pleuran (beta-glucan from Pleurotus ostreatus) supplementation, cellular immune response and respiratory tract infections in athletes. Eur.J.Appl.Physiol 2011;111(9):2033-2040.
- Talbott S, Talbott J. Effect of beta 1,3/1,6 glucan on respiratory tract infection symptoms and mood state in marathon athletes. J Sports Sci Med 2009;8(4):509-515.
- Feldman S, Schwartz HI Kalman DS Mayers A Kohrman HM Clemens R Krieger DR. Randomized phase II clinical trials of Wellmune WGP® for immune support during cold and flu season. The Journal of Applied Research 2009;9(1-2):30-42.
- McFarlin BK, Carpenter KC, Davidson T, McFarlin MA. Baker's yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise. J Diet Suppl. 2013;10(3):171-83. PubMed
- Jesenak M, Urbancek S, Majtan J, Banovcin P, Hercogova J. ß-Glucan-based cream (containing pleuran isolated from pleurotus ostreatus) in supportive treatment of mild-to-moderate atopic dermatitis. J Dermatolog Treat 2016;27(4):351-4.
- Mah E, Kaden VN, Kelley KM, Liska DJ. Beverage containing dispersible yeast ß-glucan decreases cold/flu symptomatic days after intense exercise: a randomized controlled trial. J Diet Suppl 2020;17(2):200-10. PubMed
- Zhong K, Liu Z, Lu Y, Xu X. Effects of yeast ß-glucans for the prevention and treatment of upper respiratory tract infection in healthy subjects: a systematic review and meta-analysis. Eur J Nutr. 2021. PubMed
- Cardenas FI, Mauguen A, Cheung IY, et al. Phase I trial of oral yeast-derived ß-glucan to enhance anti-GD2 immunotherapy of resistant high-risk neuroblastoma. Cancers (Basel) 2021;13(24):6265. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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