Interactions on record — worth a quick check against your medications. Based on 1 of 6 ingredients. Check your meds →
Dietary supplement

Immune Health Ingredients & Drug Interactions

by Life Extension FLORASSIST

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Immune Health is a dietary supplement by Life Extension FLORASSIST with 6 active ingredients. Its ingredients are commonly taken for digestive health and bloating, diarrhea support, immune support.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bacillus subtilis CU1. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Immune Health by Life Extension FLORASSIST

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 6 active ingredients.
  • “Immune Probiotic Blend” is a proprietary blend — the label doesn't break down how much of each component you get.

This product contains six active probiotic ingredients: an Immune Probiotic Blend that includes B. lactis BS01, L. plantarum LP01 and LP02, L. rhamnosus LR04 and LR05, and Bacillus subtilis CU1. Probiotics are live beneficial bacteria meant to support digestive and immune health.

The remaining ingredients — microcrystalline cellulose, monoglyceride, vegetable cellulose, maltodextrin, stearic acid, and silica — are inactive fillers and binders that help form and stabilize the capsule.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Bacillus Subtilis's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: immune health support.
  • We looked for evidence on: immune function, infection prevention, pathogen resistance.
  • The closest evidence on file: Bacillus Subtilis is rated "Insufficient Reliable Evidence To Rate" for Clostridioides difficile infection (Natural Medicines).

The evidence we hold is limited and mixed. Bacillus subtilis is rated Possibly Effective for antibiotic-associated diarrhea (diarrhea that develops after taking antibiotics).

For other uses — athletic performance, cirrhosis support, constipation, eczema, and diabetes — the evidence is insufficient to rate either way. That doesn't mean the product won't help; it means the research isn't conclusive yet.

For the other five strains in this blend, we don't hold effectiveness data.

The evidence, ingredient by ingredient Bacillus Subtilis

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bacillus subtilis is generally well tolerated in healthy adults, though quality and safety can vary by product and strain. Safety data is limited, so it's wise to talk with your doctor before starting it, especially if you have any chronic health conditions.

In clinical trials, one participant reported a headache, and diarrhea has been reported rarely. There are isolated cases of serious infection (bacteremia and meningitis) linked to frequent consumption of natto (fermented soybeans containing B. subtilis var. natto), mostly in people with weakened immune systems or other serious illnesses — this is not typical with probiotic supplements at standard doses, but it's worth knowing.

For the other five strains, we don't hold detailed safety information on file.

Side effects, ingredient by ingredient Bacillus Subtilis

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Bacillus Subtilis.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antibiotic drugs, check with your doctor or pharmacist about timing — you'll want to separate this supplement from your antibiotics by a few hours to keep the probiotics alive and working. For the other probiotic strains in this blend, we don't hold interaction data, so run your exact medications through the checker on this page to be sure.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This is a multi-strain probiotic that may help with antibiotic-associated diarrhea, though the evidence for other uses isn't established. If you take antibiotics, space them apart from this supplement to protect the live organisms.

Talk with your doctor before starting, especially if you have a weakened immune system or are dealing with serious illness.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 25, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Immune Health, straight from the product label.

Brand Life Extension FLORASSIST
Barcode (UPC) 737870212430
Net contents 30 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jan 25, 2020
DSLD ID 210848
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Immune Health by Life Extension FLORASSIST, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetarian Capsule(s)
Maximum serving Sizes:
1 Vegetarian Capsule(s)
UPC/BARCODE
737870212430
IngredientAmount% DV
Immune Probiotic Blend0 NP--
B. lactis BS010 NP--
L. plantarum LP010 NP--
L. plantarum LP020 NP--
L. rhamnosus LR040 NP--
L. rhamnosus LR050 NP--
Bacillus subtilis CU10 NP--

Other ingredients: Microcrystalline Cellulose, Monoglyceride, Vegetable Cellulose, Maltodextrin, Stearic Acid, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Scan for product info

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Suggested/Recommended/Usage/Directions

Read the entire label and follow directions carefully prior to use. Directions: Take one (1) capsule daily, with or without food, or as recommended by a healthcare practitioner.

Formulation

Non-GMO

Probiotic support for a healthy immune response

Storage

Store tightly closed in a cool, dry place.

Precautions

Warnings: Keep out of reach of children.

Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Contains soybeans.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

See for yourself

Immune Health by Life Extension FLORASSIST label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Immune Health by Life Extension FLORASSIST

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Vegetarian Capsule(s) Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Immune Probiotic Blend

0 NP per serving
  • › B. lactis BS01
  • › L. plantarum LP01
  • › L. plantarum LP02
  • › L. rhamnosus LR04
  • › L. rhamnosus LR05

Bacillus subtilis CU1

Interacts with
182 drugs
0 NP per serving

Bacillus subtilis is a spore-forming probiotic bacterium found in soil and some fermented foods, and it is used mainly to support gut health and diges...

Bacillus subtilis CU1 monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Monoglyceride, Vegetable Cellulose, Maltodextrin, Stearic Acid, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Immune Health by Life Extension FLORASSIST Drug Interactions

Want to check YOUR meds against Immune Health?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Immune Health with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bacillus subtilis CU11 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B. subtilis.
Since B. subtilis preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. subtilis preparations by at least 2 hours.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Immune Health, from the product label.

Life Extension FLORASSIST

Name
Quality Supplements and Vitamins, Inc.
City
Ft. Lauderdale
State
FL
ZipCode
33309
Phone Number
1-866-280-2852
Web Address
LifeExtension.com
Pharmacist Counseling Corner

Immune Health by Life Extension FLORASSIST: Common Questions

Does Immune Health by Life Extension FLORASSIST interact with any medications?
Yes. Based on its ingredients, Immune Health has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Immune Health contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this help prevent diarrhea after antibiotics?
Bacillus subtilis in this blend is rated Possibly Effective for antibiotic-associated diarrhea. That means some research supports it, but the evidence isn't rock-solid yet. Talk with your doctor about whether it makes sense for you.
When should I take this if I'm on antibiotics?
Take this supplement and your antibiotics a few hours apart — don't take them at the same time. Antibiotics can kill the live organisms in the probiotic, which defeats the purpose. Ask your doctor or pharmacist for the best timing for your specific situation.
What are these probiotic strains?
Probiotics are live beneficial bacteria. This product contains six different strains — a blend of Bacillus lactis, Lactobacillus plantarum, and Lactobacillus rhamnosus — each with a specific strain designation. Together they're meant to support digestive and immune health.
Are there any side effects?
Bacillus subtilis is generally well tolerated. In trials, one person reported a headache, and diarrhea has been reported rarely. If you have a weakened immune system or a serious chronic illness, talk with your doctor first — there are isolated historical cases of serious infection tied to very high consumption of fermented foods containing a related Bacillus strain.
Can I take this if I'm pregnant or breastfeeding?
The safety data for these probiotic strains isn't established for pregnancy or breastfeeding. Talk with your doctor or pharmacist for personalized advice on whether it's right for you at this time.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Immune Health is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Immune Health label
Sources

Sources & How We Checked

Immune Health's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bacillus Subtilis 10 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Lampropoulos PK, Gkentzi D, Tzifas S, Dimitriou G. Neonatal sepsis due to Bacillus subtilis. Cureus 2021;13(9):e17692. PubMed
  3. La Jeon Y, Yang JJ, Kim MJ, et al. Combined Bacillus licheniformis and Bacillus subtilis infection in a patient with oesophageal perforation. J Med Microbiol 2012;61(Pt 12):1766-1769. PubMed
  4. Wallet F, Crunelle V, Roussel-Delvallez M, Fruchart A, Saunier P, Courcol RJ. Bacillus subtilis as a cause of cholangitis in polycystic kidney and liver disease. Am J Gastroenterol 1996;91(7):1477-8.
  5. Velasco E, Martins CA, Tabak D, Bouzas LF. "Bacillus subtilis" infection in a patient submitted to a bone marrow transplantation. Rev Paul Med 1992;110(3):116-7.
  6. Kato A, Yoshifuji A, Komori K, et al. A case of Bacillus subtilis var. natto bacteremia caused by ingestion of natto during COVID-19 treatment in a maintenance hemodialysis patient with multiple myeloma. J Infect Chemother 2022;28(8):1212-1215. PubMed
  7. Freedman KE, Hill JL, Wei Y, et al. Examining the gastrointestinal and immunomodulatory effects of the novel probiotic Bacillus subtilis DE111. Int J Mol Sci 2021;22(5):2453. PubMed
  8. Lefevre M, Racedo SM, Denayrolles M, et al. Safety assessment of Bacillus subtilis CU1 for use as a probiotic in humans. Regul Toxicol Pharmacol 2017;83:54-65. PubMed
  9. Hanifi A, Culpepper T, Mai V, et al. Evaluation of Bacillus subtilis R0179 on gastrointestinal viability and general wellness: a randomised, double-blind, placebo-controlled trial in healthy adults. Benef Microbes 2015;6(1):19-27. PubMed
  10. Tokano M, Tarumoto N, Imai K, et al. A case of bacterial meningitis caused by Bacillus subtilis var. natto. Intern Med. 2022. Epub ahead of print.

See these in context on the Bacillus Subtilis monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring