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Dietary supplement

IP-6 Ingredients & Drug Interactions

by NutraBio

Powder Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

IP-6 is a dietary supplement by NutraBio with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, cancer prevention interest, kidney stone prevention.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are IP-6. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of IP-6 by NutraBio

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

NutraBio IP-6 is a single-ingredient supplement—just IP-6 (also called inositol hexaphosphate), a naturally occurring compound found in plants. There are no inactive ingredients listed in this formulation.

Does it work?

No specific claim
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
General wellness

This Ip-6 product is marketed for general wellness, not a specific health condition, so there's no single claim to grade — see Ip-6's own graded uses on its monograph.

Why this rating?
  • The label markets general wellness (“Antioxidant”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.

The evidence supporting IP-6 for its commonly advertised uses isn't established in the data we hold. We found insufficient reliable evidence to rate it for chemotherapy-induced low white blood cell counts (a side effect of cancer treatment) and gout.

If you're thinking about this supplement for a specific health reason, your doctor or pharmacist can discuss what the broader research suggests and whether it's the right choice for you.

The evidence, ingredient by ingredient Ip-6

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

IP-6 is generally considered low-risk in the amounts found naturally in food, but supplement safety isn't well studied. One important caution: it can reduce the absorption of minerals (like iron and zinc), so if you take mineral supplements or have mineral absorption concerns, that's worth discussing with your healthcare provider.

Don't use supplemental IP-6 during pregnancy or while breastfeeding—there isn't enough safety information to know either way, and the safety data advises against it. Talk with your doctor or pharmacist about what's appropriate for you.

Side effects, ingredient by ingredient Ip-6

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Ip-6.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Blood thinners and antiplatelet drugs (medications like warfarin, newer anticoagulants, aspirin, or clopidogrel) are the main ones to double-check before taking this product. These 122 medications could theoretically face an increased bleeding risk with IP-6.

Run the checker on this page with your exact medication list, or ask your doctor or pharmacist to review it.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula marketed for general wellness rather than one specific gradeable purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.

IP-6 is a single-ingredient supplement with minimal side effects reported, but its effectiveness for most uses hasn't been well established. The main concern is that it may increase bleeding risk if you take blood thinners or antiplatelet drugs.

If you're on any medication that affects clotting, check with your doctor or pharmacist before starting this product.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 22, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about IP-6, straight from the product label.

Brand NutraBio
Barcode (UPC) 649908246303
Net contents 150 Gram(s); 5.3 oz.
Market status On market
Date entered into DSLD Oct 22, 2015
DSLD ID 51068
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Kosher, No Allergies, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for IP-6 by NutraBio, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Scoop(s)
Maximum serving Sizes:
2 Scoop(s)
Servings per container
300
UPC/BARCODE
649908246303
IngredientAmount% DV
IP-6500 mg--

Other ingredients: Absolutely None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Warning: Not intended for use by persons under the age of 18. Keep out of the reach of children.

If you are pregnant, breastfeeding, have known medical conditions (including kidney or liver disease) or are taking prescription or OTC medication(s) consult with your health care practitioner before using this product.

IP6 is an efficient mineral chelator and therefore should NOT be taken at the same time of day as minerals or medications.

General Statements

Manufactured in a GMP & FDA Inspected Facility

Quality and purity since 1996. NutraBio manufactures in our own FDA registered & inspected GMP facility complying with FDA 21 CFR Part 111 regulations.

Antioxidant

Pharmaceutical Grade - HPLC Lab Tested for Potency

Serving Scoop Included. (May settle to the bottom during shipping.)

Since 1996

Powder 300 Servings

Formula

Inositol Hexaphosphate

OU

Formulation

No fillers - No excipients - No additives

Free of Harmful Impurities

Allergen Free - Non-GMO - Gluten Free - BSE/TSE Free

Vegetarian

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

OU

Made in a GMP & FDA Inspected Facility

True Label Full Label Disclosure

Storage

Store in cool dry place.

FDA Disclaimer Statement

+ These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

24630-007 B20266-003

Suggested/Recommended/Usage/Directions

1-2 servings - Mixed with 8-16 oz. - Favorite Beverage - 2x daily - Before meals

Suggested Use: As a dietary supplement, take 1 to 2 servings 2 times daily between or before meals, or as directed by your physician. Bets taken on an empty stomach. IP6 is an efficient mineral chelator and therefore should NOT be taken at the same time of day as minerals or medications.

See for yourself

IP-6 by NutraBio label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in IP-6 by NutraBio

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Scoop(s) Dosage formPowder Servings per container300 Amounts shown are per serving.

IP-6

Interacts with
122 drugs
500 mg per serving

IP-6 (inositol hexaphosphate, also called phytic acid or phytate) is a natural compound found in high-fiber plant foods and sold as a supplement, ofte...

IP-6 monograph & interactions

Other (inactive) ingredients: Absolutely None. These complete the product’s ingredient list but are not active constituents.

Interaction report

IP-6 by NutraBio Drug Interactions

Want to check YOUR meds against IP-6?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
122Drugs
122 Moderate

Ingredients driving the most interactions

IP-6 122

Each ingredient & the kinds of drugs it affects

For each ingredient in IP-6 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

IP-61 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, concomitant use of IP-6 with drugs that affect platelet aggregation may increase the risk of bleeding. In vitro IP-6 can inhibit platelet aggregation. This effect has not been demonstrated in humans.

Likelihood Unlikely Evidence D
The maker

Brand information

Manufacturer and brand details for IP-6, from the product label.

NutraBio

See all NutraBio products
Name
NutraBio Labs, Inc.
Street Address
564 Lincoln Blvd.
City
Middlesex
State
NJ
ZipCode
08846
Phone Number
732-748-8606
Web Address
www.nutrabio.com
Pharmacist Counseling Corner

IP-6 by NutraBio: Common Questions

Does IP-6 by NutraBio interact with any medications?
Yes. Based on its ingredients, IP-6 has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
IP-6 contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take IP-6 if I'm on aspirin or another blood thinner?
Not without checking first. IP-6 may theoretically increase bleeding risk with these drugs, though human studies haven't confirmed it yet. Talk with your doctor or pharmacist—they know your dose and situation and can say whether it's okay or if you need monitoring.
Does IP-6 have side effects?
No adverse effects are documented in our data, and it's generally considered low-risk. One thing to watch: it can reduce how well your body absorbs minerals like iron and zinc, so if you take mineral supplements, mention this product to your pharmacist.
Is this supplement safe during pregnancy or while breastfeeding?
There isn't enough safety information to know either way. The available data advises against using supplemental IP-6 in pregnancy and while breastfeeding. Talk with your doctor about what's safe for you.
Does IP-6 actually work for chemotherapy side effects or gout?
The evidence isn't established in our data. We found insufficient reliable evidence to rate it for chemotherapy-induced low white blood cell counts or for gout. If you're considering it for one of these reasons, ask your doctor or pharmacist what the research shows.
What exactly is IP-6?
IP-6, or inositol hexaphosphate, is a naturally occurring compound found in plants. It's a single active ingredient—this NutraBio powder has nothing else added to it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if IP-6 is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

IP-6 label
Sources

Sources & How We Checked

IP-6's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Ip-6 3 references
  1. Steinmetz KA, Potter JD. Vegetables, fruit, and cancer prevention: a review. J Am Diet Assoc 1996;96:1027-39. PubMed
  2. Vucenik I, Podczasy JJ, Shamsuddin AM. Antiplatelet activity of inositol hexaphosphate. Anticancer Res 1999;19:3689-93.
  3. Ikenaga T, Kakumoto K, Kohda N, Yamamoto T. Effect of Inositol Hexaphosphate (IP6) on Serum Uric Acid in Hyperuricemic Subjects: a Randomized, Double-Blind, Placebo-Controlled, Crossover Study. Plant Foods Hum Nutr. 2019 Sep;74(3):316-321. DOI

See these in context on the Ip-6 monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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