Interactions on record — worth a quick check against your medications. Based on 3 of 6 ingredients. Check your meds →
Dietary supplement

Isopure Aminos Cherry Lime Ingredients & Drug Interactions

by Nature's Best

Powder Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Isopure Aminos Cherry Lime is a dietary supplement by Nature's Best with 6 active ingredients. Its ingredients are commonly taken for common cold and immune support, antioxidant support, skin health and collagen formation.Based on those ingredients, 709 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Theanine, Vitamin C. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Isopure Aminos Cherry Lime by Nature's Best

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 3 of its 6 active ingredients.
  • “BCAA Blast Ethyl Ester Recovery Complex” is a proprietary blend — the label gives one combined amount (5 Gram(s)) without saying how much of each component you get.

Isopure Aminos Cherry Lime contains 6 active ingredients. The branched-chain amino acids (BCAAs) — L-leucine, L-isoleucine, and L-valine — are building blocks your body uses for muscle recovery and repair.

Vitamin C supports immune function and collagen formation. L-theanine is an amino acid thought to promote relaxation and focus.

Tart cherry extract is added for its potential role in muscle recovery and athletic performance. The product also contains inactive ingredients — natural and artificial flavor, citric acid, malic acid, tartaric acid, silicon dioxide, calcium silicate, soy lecithin, sucralose, and FD&C Red 40 — which serve as flavor enhancers, acids, anti-caking agents, and color.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: head to toe recovery and muscle soreness.
  • We looked for evidence on: Exercise-induced muscle soreness, Exercise-induced muscle damage, Athletic performance, post-exercise recovery, exercise recovery, BCAA supplementation.
  • The strongest evidence on file: Sour Cherry is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Sour Cherry is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle soreness.
  • Also on file: Vitamin C is rated "Insufficient Reliable Evidence To Rate" for Athletic performance, Exercise-induced muscle damage.

Vitamin C is effective for preventing vitamin C deficiency and possibly effective for reducing anemia related to chronic disease, supporting atrial fibrillation management, preventing cataracts, and reducing exercise-induced respiratory infections. L-theanine is possibly effective for cognitive function; evidence for its use in age-related cognitive decline, Alzheimer disease, anxiety, OCD, and cancer is insufficient.

Tart cherry extract is possibly effective for athletic performance; evidence for ADHD, cognitive function, exercise-related muscle soreness, respiratory infections, and fibromyalgia is insufficient. The BCAAs (leucine, isoleucine, valine) have no effectiveness data on file here.

The evidence, ingredient by ingredient Vitamin C Theanine Sour Cherry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin C is generally well tolerated at normal supplement doses, though very high doses can cause side effects. Orally, the most common ones are abdominal cramps, heartburn, diarrhea, nausea, and headache — more likely above 2 grams daily.

Kidney stones have been reported in people prone to them. Tart cherry is generally well tolerated as whole fruit or juice, though concentrated supplements are less studied; some trial participants reported abdominal pain and loose stools.

L-theanine may cause headaches, drowsiness, or increased dream activity and is generally well tolerated short-term in healthy adults, though long-term safety isn't well established. For pregnancy, normal dietary amounts of vitamin C are considered safe, but avoid high-dose supplements unless your doctor advises otherwise.

Safety data for L-theanine in pregnancy is insufficient — talk with your doctor or pharmacist for personalized guidance. Tart cherry as food is likely safe in pregnancy.

For breastfeeding, avoid high-dose vitamin C supplements and L-theanine; safety data on concentrated tart cherry supplements is limited.

Side effects, ingredient by ingredient Vitamin C Theanine Sour Cherry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Vitamin C, Theanine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; cancer treatments.
  • For scale: 709 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check this product with your doctor or pharmacist before using if you take blood thinners like warfarin (Moderate), estrogens in oral contraceptives or hormone replacement therapy (Moderate), blood pressure medications (Moderate), chemotherapy drugs including alkylating agents or antitumor antibiotics (Moderate), aluminum-containing antacids or supplements (Moderate), the antipsychotic fluphenazine (Moderate), the HIV drug indinavir (Moderate), levothyroxine for thyroid disease (Moderate), or CNS depressants like sleep aids or sedatives (Minor).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may appeal to athletes or active people interested in muscle recovery and immune support. Anyone taking blood thinners, estrogen-based contraceptives or hormone therapy, blood pressure medications, chemotherapy, or thyroid medication should check their specific prescriptions with their doctor or pharmacist before using this product, as vitamin C interactions are possible.

Talk it over with your own healthcare provider to see if it fits your routine.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 22, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Isopure Aminos Cherry Lime, straight from the product label.

Brand Nature's Best
Barcode (UPC) 089094023416
Net contents 10.05 oz.; 285 Gram(s)
Market status On market
Date entered into DSLD Apr 22, 2016
DSLD ID 58820
Product type Other Combinations
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Isopure Aminos Cherry Lime by Nature's Best, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
9.5 Gram(s)
Maximum serving Sizes:
9.5 Gram(s)
Servings per container
30
UPC/BARCODE
089094023416
IngredientAmount% DV
Calories10 {Calories}--
Total Carbohydrates2 Gram(s)1%
L-Leucine0 NP--
L-Isoleucine0 NP--
L-Valine0 NP--
Vitamin C30 mg50%
L-Theanine100 mg--
BCAA Blast Ethyl Ester Recovery Complex5 Gram(s)--
Tart Cherry Extract700 mg--

Other ingredients: Natural and Artificial flavor, Citric Acid, Malic Acid, Tartaric Acid, Silicon Dioxide, Calcium Silicate, Soy Lecithin, Sucralose, FD&C Red 40

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

5 GRAMS BCAA’S PER SERVING 700 MG TART CHERRY PER SERVING 100 MG L-THEANINE PER SERVING ANTIOXIDANT VITAMIN C 10 CALORIES

Proven BCAA’S meet the new-to-the-world combination of Tart Cherry, an anti-inflammatory that helps reduce soreness following intense exercise, and L-Theanine for a calm, relaxed mind. Together they help you make the most of your recovery and hit it harder the next day. Packed with antioxidant Vitamin C, we’ve crafted a lean amino acid powder unlike any other – and the only from Isopure – so you can make more of your muscles.

BCAA’S, TART CHERRY EXTRACT & L-THEANINE FOR HEAD TO TOE RECOVERY

Contains Soy.

Brand IP Statement(s)

HEAD TO TOE RECOVERY

CherryPURE is a registered trademark of Shoreline Fruit, LLC

General Statements

INSTANTIZED WE’RE ALL MORE THAN MUSCLE NOT ALL AMINO ACIDS ARE CREATED EQUAL Introducing a forward-thinking formula to support comprehensive body and mind benefits.

NATURALLY & ARTIFICIALLY FLAVORED

Contents sold by weight, not volume.

Made in the USA-This product contains ingredients of international and domestic origin.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

CherryPURE

General

V.1.341.0615US 6033362

FDA Statement of Identity

AMINO SUPPLEMENT

Precautions

Contains Soy.

Warning: Consult your physician before using this product if you are taking any medications or are under a physician’s care for a medical condition. Not for use by those under the age of 18, or women that are pregnant, trying to get pregnant, or nursing.

Not for use by those under the age of 18, or women that are pregnant, trying to get pregnant, or nursing.

Storage

Keep in a cool, dry place.

Suggested/Recommended/Usage/Directions

Directions : Mix one scoop with 10-12 fl oz of water in a shaker or blender. If a shaker or a blender is not convenient, ISOPURE AMINOS can be stirred into solution with a spoon. Take 2 servings per day in addition to your ISOPURE protein drink. Optimal timing is post-workout and bedtime.

See for yourself

Isopure Aminos Cherry Lime by Nature's Best label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Isopure Aminos Cherry Lime by Nature's Best

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size9.5 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin C

Interacts with
207 drugs
30 mg per serving Form: Ascorbic Acid

Vitamin C (ascorbic acid) is an essential nutrient your body needs but cannot make, so you must get it from food or supplements. It's important for im...

Vitamin C monograph & interactions

L-Theanine

Interacts with
565 drugs
100 mg per serving

Theanine (usually L-theanine) is an amino acid found naturally in tea leaves that many people take to feel calmer and less stressed without strong dro...

L-Theanine monograph & interactions

BCAA Blast Ethyl Ester Recovery Complex

5 Gram(s) per serving
  • › L-Leucine
  • › L-Isoleucine
  • › L-Valine

Tart Cherry Extract

No known
interactions
700 mg per serving Form: Montmorency Tart Cherries

Sour cherry (often sold as tart cherry or Montmorency cherry) is a fruit-based supplement rich in antioxidants that people use for muscle recovery, jo...

Tart Cherry Extract monograph & interactions

Other (inactive) ingredients: Natural and Artificial flavor, Citric Acid, Malic Acid, Tartaric Acid, Silicon Dioxide, Calcium Silicate, Soy Lecithin, Sucralose, FD&C Red 40. These complete the product’s ingredient list but are not active constituents.

Interaction report

Isopure Aminos Cherry Lime by Nature's Best Drug Interactions

Want to check YOUR meds against Isopure Aminos Cherry Lime?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
709Drugs
273 Moderate 436 Minor

Ingredients driving the most interactions

Vitamin C 207

Each ingredient & the kinds of drugs it affects

For each ingredient in Isopure Aminos Cherry Lime with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Theanine3 drug types · 565 drugs

Antihypertensive Drugs

Theanine might lower blood pressure, potentiating the effects of antihypertensive drugs.
Animal research shows that theanine can lower blood pressure in spontaneously hypertensive animals. Theoretically, concomitant use of theanine and antihypertensive drugs might potentiate the antihypertensive activity.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants. However, it is unclear if this concern is clinically relevant.
Theoretically, theanine may compete with glutamate and/or increase plasma gamma-aminobutyric acid (GABA) levels, which could cause CNS depression. In one clinical study, some subjects taking oral theanine reported drowsiness.

Likelihood Unlikely Evidence D
Serotonergic Drugs

Clinical studies regarding the effects of L-theanine on serotonin levels are conflicting. Some studies suggest it can increase serotonin levels in the brain while others report that it may decrease them. Nevertheless, there have been no reports of l-theanine being a causative agent in serotonergic-related side effects or serotonin syndrome.

Likelihood Unlikely Evidence C

Vitamin C13 drug types · 207 drugs

Alkylating Agents

Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
The use of antioxidants like vitamin C during chemotherapy is controversial. There is concern that antioxidants could reduce the activity of chemotherapy drugs that generate free radicals, such as cyclophosphamide, chlorambucil, carmustine, busulfan, and thiotepa. In contrast, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as vitamin C have on chemotherapy.

Likelihood Possible Evidence D
Aluminum

Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Research in animals and humans shows that vitamin C increases aluminum absorption, theoretically by chelating aluminum and keeping it in solution where it is available for absorption. In people with normal renal function, urinary excretion of aluminum will likely increase, making aluminum retention and toxicity unlikely. Patients with renal failure who take aluminum-containing compounds such as phosphate binders should avoid vitamin C supplements in doses above the recommended dietary allowances.

Likelihood Probable Evidence B
Antitumor Antibiotics

Theoretically, the antioxidant effects of vitamin C might reduce the effectiveness of antitumor antibiotics.
The use of antioxidants like vitamin C during chemotherapy is controversial. There is concern that antioxidants could reduce the activity of chemotherapy drugs which generate free radicals, such as doxorubicin. In contrast, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effects, if any, antioxidants such as vitamin C have on chemotherapy.

Likelihood Possible Evidence D
Estrogens

Vitamin C might increase blood levels of estrogens.
Increases in plasma estrogen levels of up to 55% occur under some circumstances when vitamin C is taken concurrently with oral contraceptives or hormone replacement therapy, including topical products. It is suggested that vitamin C prevents oxidation of estrogen in the tissues, regenerates oxidized estrogen, and reduces sulfate conjugation of estrogen in the gut wall. When tissue levels of vitamin C are high, these processes are already maximized and supplemental vitamin C does not have any effect on estrogen levels. Increases in plasma estrogen levels may occur when patients who are deficient in vitamin C take supplements. Monitor these patients for estrogen-related side effects.

Likelihood Probable Evidence B
Fluphenazine (Prolixin)

Theoretically, vitamin C might decrease levels of fluphenazine.
In one patient there was a clinically significant decrease in fluphenazine levels when vitamin C (500 mg twice daily) was started. The mechanism is not known, and there is no further data to confirm this interaction.

Likelihood Possible Evidence D
Indinavir (Crixivan)

Vitamin C can modestly reduce indinavir levels.
One pharmacokinetic study shows that taking vitamin C 1 gram orally once daily along with indinavir 800 mg orally three times daily reduces the area under the concentration-time curve of indinavir by 14%. The mechanism of this interaction is unknown, but it is unlikely to be clinically significant in most patients. The effect of higher doses of vitamin C on indinavir levels is unknown.

Likelihood Probable Evidence B
Levothyroxine (Synthroid, Others)

Vitamin C can increase levothyroxine absorption.
Two clinical studies in adults with poorly controlled hypothyroidism show that swallowing levothyroxine with a glass of water containing vitamin C 500-1000 mg in solution reduces thyroid stimulating hormone (TSH) levels and increases thyroxine (T4) levels when compared with taking levothyroxine alone. This suggests that vitamin C increases the oral absorption of levothyroxine, possibly due to a reduction in pH.

Likelihood Probable Evidence B
Warfarin (Coumadin)

High-dose vitamin C might reduce the levels and effectiveness of warfarin.
Vitamin C in high doses may cause diarrhea and possibly reduce warfarin absorption. There are reports of two people who took up to 16 grams daily of vitamin C and had a reduction in prothrombin time. Lower doses of 5-10 grams daily can also reduce warfarin absorption. In many cases, this does not seem to be clinically significant. However, a case of warfarin resistance has been reported for a patient who took vitamin C 500 mg twice daily. Cessation of vitamin C supplementation resulted in a rapid increase in international normalized ratio (INR). Tell patients taking warfarin to avoid taking vitamin C in excessively high doses (greater than 10 grams daily). Lower doses may be safe, but the anticoagulation activity of warfarin should be monitored. Patients who are stabilized on warfarin while taking vitamin C should avoid adjusting vitamin C dosage to prevent the possibility of warfarin resistance.

Likelihood Possible Evidence D
Acetaminophen (Tylenol, Others)

High-dose vitamin C might slightly prolong the clearance of acetaminophen.
A small pharmacokinetic study in healthy volunteers shows that taking high-dose vitamin C (3 grams) 1.5 hours after taking acetaminophen 1 gram slightly increases the apparent half-life of acetaminophen from around 2.3 hours to 3.1 hours. Ascorbic acid competitively inhibits sulfate conjugation of acetaminophen. However, to compensate, elimination of acetaminophen glucuronide and unconjugated acetaminophen increases. This effect is not likely to be clinically significant.

Likelihood Probable Evidence B
Aspirin

Acidification of the urine by vitamin C might increase aspirin levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction is not clinically significant.

Likelihood Possible Evidence B
Choline Magnesium Trisalicylate (Trilisate)

Acidification of the urine by vitamin C might increase choline magnesium trisalicylate levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction probably is not clinically significant.

Likelihood Possible Evidence B
Niacin

Vitamin C might decrease the beneficial effects of niacin on high-density lipoprotein (HDL) cholesterol levels.
A combination of niacin and simvastatin (Zocor) effectively raises HDL cholesterol levels in patients with coronary disease and low HDL levels. Clinical research shows that taking a combination of antioxidants (vitamin C, vitamin E, beta-carotene, and selenium) along with niacin and simvastatin (Zocor) attenuates this rise in HDL, specifically the HDL-2 and apolipoprotein A1 fractions, by more than 50% in patients with coronary disease. It is not known whether this adverse effect is due to a single antioxidant such as vitamin C, or to the combination. It also is not known whether it will occur in other patient populations.

Likelihood Possible Evidence A
Salsalate (Disalcid)

Acidification of the urine by vitamin C might increase salsalate levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams/day vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction probably is not clinically significant.

Likelihood Possible Evidence B
The maker

Brand information

Manufacturer and brand details for Isopure Aminos Cherry Lime, from the product label.

Nature's Best

See all Nature's Best products
Name
Nature's Best, Inc.
Street Address
195 Engineers Road
City
Hauppauge
State
NY
ZipCode
11788
Web Address
theisopurecompany.com
Pharmacist Counseling Corner

Isopure Aminos Cherry Lime by Nature's Best: Common Questions

Does Isopure Aminos Cherry Lime by Nature's Best interact with any medications?
Yes. Based on its ingredients, Isopure Aminos Cherry Lime has a known interaction with 709 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Isopure Aminos Cherry Lime contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take if I'm pregnant or breastfeeding?
Normal dietary amounts of vitamin C are fine in pregnancy, but this product's vitamin C dose is higher — avoid high-dose supplements unless your doctor says it's okay. L-theanine hasn't been studied enough in pregnancy; there's insufficient data to know if it's safe, so talk with your doctor or pharmacist before taking it. Breastfeeding: avoid high-dose vitamin C supplements and L-theanine unless your healthcare provider advises otherwise; safety data on concentrated tart cherry isn't established.
Can vitamin C in this product affect my birth control or hormone therapy?
Yes. Vitamin C may increase blood estrogen levels when taken alongside oral contraceptives or hormone replacement therapy, including topical products. If you use hormonal birth control or hormone therapy, check with your doctor or pharmacist before starting this product.
What side effects might I experience from this powder?
Vitamin C at higher doses can cause abdominal cramps, heartburn, diarrhea, nausea, and headache — more likely above 2 grams daily. L-theanine may cause headaches, drowsiness, or increased dreams. Tart cherry may cause abdominal pain or loose stools in some people. If you have a history of kidney stones, be aware vitamin C can increase risk at high doses.
Does this actually help with muscle recovery?
Tart cherry extract is possibly effective for athletic performance, though evidence for exercise-related muscle soreness specifically is insufficient in our data. The BCAAs (leucine, isoleucine, and valine) are amino acids that support muscle repair, but we don't hold effectiveness ratings for them here.
Is this product safe to use with my seizure medication or other CNS depressants?
L-theanine theoretically may add to the sedative effects of CNS depressants like sleep aids, sedatives, or anti-anxiety medications, though it's unclear how clinically relevant this is. Talk with your doctor or pharmacist before combining this product with any CNS depressant medication.
Can this interfere with my thyroid medication?
Yes. Vitamin C can increase how much levothyroxine your body absorbs, which may affect your thyroid hormone levels. If you take levothyroxine (Synthroid or another brand), check with your doctor or pharmacist before starting this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Isopure Aminos Cherry Lime label
Sources

Sources & How We Checked

Isopure Aminos Cherry Lime's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 61 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin C 51 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Back DJ, Breckenridge AM, MacIver M, et al. Interaction of ethinyloestradiol with ascorbic acid in man. Br Med J (Clin Res Ed) 1981;282:1516.
  3. Morris JC, Beeley L, Ballantine N. Interaction of ethinyloestradiol with ascorbic acid in man [letter]. Br Med J (Clin Res Ed) 1981;283:503.
  4. Labriola D, Livingston R. Possible interactions between dietary antioxidants and chemotherapy. Oncology 1999;13:1003-8.
  5. Dwyer JH, Merz NB, Shirocre AM, et al. Progression of early atherosclerosis and intake of vitamin C and vitamin E from supplements and food. The Los Angeles Atherosclerosis Study. 41st Annual Conference on Cardiovascular Disease Epidemiology and Prevent
  6. Levine M, Rumsey SC, Daruwala R, et al. Criteria and recommendations for vitamin C intake. JAMA 1999;281:1415-23. PubMed
  7. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  8. Segal S, Kaminski S. Drug-nutrient interactions. American Druggist 1996 Jul;42-8.
  9. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, DC: National Academy Press, 2000. Available at: http://www.nap.edu/books/0309069351/html/.
  10. Houston JB, Levy G. Drug biotransformation interactions in man VI: Acetaminophen and ascorbic acid. J Pharm Sci 1976;65:1218-21. PubMed
  11. Brown BG, Zhao XQ, Chait A, et al. Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease. N Engl J Med 2001;345:1583-93. DOI
  12. Rosenthal G. Interaction of ascorbic acid and warfarin. JAMA 1971;215:1671. DOI
  13. Hume R, Johnstone JM, Weyers E. Interaction of ascorbic acid and warfarin. JAMA 1972;219:1479. DOI
  14. Smith EC, Skalski RJ, Johnson GC, Rossi GV. Interaction of ascorbic acid and warfarin. JAMA 1972;221:1166. DOI
  15. Traxer O, Huet B, Poindexter J, et al. Effect of ascorbic acid consumption on urinary stone risk factors. J Urol 2003;170:397-401.. PubMed
  16. Domingo JL, Gomez M, Llobet JM, Richart C. Effect of ascorbic acid on gastrointestinal aluminum absorption (letter). Lancet 1991;338:1467.
  17. Domingo JL, Gomez M, Llobet JM, Corbella J. Influence of some dietary constituents on aluminum absorption and retention in rats. Kidney Int 1991;39:598-601. PubMed
  18. Partridge NA, Regnier FE, White JL, Hem SL. Influence of dietary constituents on intestinal absorption of aluminum. Kidney Int 1989;35:1413-7. PubMed
  19. Mc Leod DC, Nahata MC. Inefficacy of ascorbic acid as a urinary acidifier (letter). N Engl J Med 1977;296:1413. DOI
  20. Hansten PD, Hayton WL. Effect of antacid and ascorbic acid on serum salicylate concentration. J Clin Pharmacol 1980;20:326-31. PubMed
  21. Dysken MW, Cumming RJ, Channon RA, Davis JM. Drug interaction between ascorbic acid and fluphenazine. JAMA 1979;241:2008. DOI
  22. Vihtamaki T, Parantainen J, Koivisto AM, et al. Oral ascorbic acid increases plasma oestradiol during postmenopausal hormone replacement therapy. Maturitas 2002;42:129-35. PubMed
  23. Slain D, Amsden JR, Khakoo RA, et al. Effect of high-dose vitamin C on the steady-state pharmacokinetics of the protease inhibitor indinavir in healthy volunteers. Pharmacotherapy 2005;25:165-70. PubMed
  24. Cheung MC, Zhao XQ, Chait A, et al. Antioxidant supplements block the response of HDL to simvastatin-niacin therapy in patients with coronary artery disease and low HDL. Arterioscler Thromb Vasc Biol 2001;21:1320-6. PubMed
  25. Feetam CL, Leach RH, Meynell MJ. Lack of a clinically important interaction between warfarin and ascorbic acid. Toxicol Appl Pharmacol 1975;31:544-7. PubMed
  26. Weintraub M, Griner PF. Warfarin and ascorbic acid: lack of evidence for a drug interaction. Toxicol Appl Pharmacol 1974;28:53-6. PubMed
  27. Lee DH, Folsom AR, Harnack L, et al. Does supplemental vitamin C increase cardiovascular disease risk in women with diabetes? Am J Clin Nutr 2004;80:1194-200. PubMed
  28. Taylor EN, Stampfer MJ, Curhan GC. Dietary factors and the risk of incident kidney stones in men: new insights after 14 years of follow-up. J Am Soc Nephrol 2004;15:3225-32. PubMed
  29. Ward NC, Hodgson JM, Croft KD, et al. The combination of vitamin C and grape-seed polyphenols increases blood pressure: a randomized, double-blind, placebo-controlled trial. J Hypertens 2005;23:427-34.. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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