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Dietary supplement

Jiaogulan 4:1 Extract Powder Ingredients & Drug Interactions

by TerraVita Premium Collection

Jiaogulan 4:1 Extract Powder label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Jiaogulan 4:1 Extract Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Jiaogulan 4:1 Extract Powder is a dietary supplement by TerraVita Premium Collection with 1 active ingredient. Its ingredients are commonly taken for fatigue and stress (adaptogen), blood sugar support, high blood pressure.Based on those ingredients, 327 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Jiaogulan Extract, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Jiaogulan 4:1 Extract Powder by TerraVita Premium Collection

Ask about any prescription or over-the-counter medication and we check it for interactions with Jiaogulan 4:1 Extract Powder by TerraVita Premium Collection — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Jiaogulan 4:1 Extract Powder by TerraVita Premium Collection

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: jiaogulan extract in a 4:1 concentrated powder form. That means the raw herb has been reduced to a stronger dose.

Jiaogulan is a plant traditionally used in herbal medicine, and this powder delivers it without any added fillers or inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Jiaogulan's overall clinical evidence instead.

Moderate

Some clinical evidence supports Jiaogulan for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Diabetes — rated "Possibly Effective" (Natural Medicines).

Jiaogulan is possibly effective for diabetes based on clinical research showing it can lower blood glucose. For athletic performance, cancer, cardiovascular disease, nonalcoholic fatty liver disease, and respiratory tract infections, the evidence we hold is insufficient — meaning we don't have reliable data yet to say whether it works for those uses.

The evidence, ingredient by ingredient Jiaogulan

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Jiaogulan is generally well tolerated when taken as a tea or supplement for short periods, but long-term safety hasn't been well studied. The most common side effects reported are diarrhea and nausea; some people also experience dry mouth, dizziness, or insomnia.

Studies show it's been well tolerated for up to 4 months of use. Do not take this product if you are pregnant — safety has not been established and it may harm the developing baby.

Avoid it while breastfeeding as well, because there isn't enough safety information. Talk with your doctor or pharmacist about whether this product is appropriate for you.

Side effects, ingredient by ingredient Jiaogulan

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Jiaogulan.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 327 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before taking this product if you use blood thinners or antiplatelet drugs (warfarin, aspirin, clopidogrel), drugs that suppress your immune system, or diabetes medications. These Moderate-severity interactions mean jiaogulan could increase bleeding risk, reduce immune-suppressing drug effectiveness, or lower blood sugar too much.

Talk with your doctor or pharmacist before combining them.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Jiaogulan may be worth considering if you're interested in blood sugar support and you don't take blood thinners, immune-suppressing drugs, or diabetes medications — or if you do, only under your doctor's supervision. Because it can thin the blood and lower blood sugar, you'll want to clear it with your own doctor or pharmacist before starting.

Avoid it entirely if you're pregnant or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Jiaogulan 4:1 Extract Powder, straight from the product label.

Brand TerraVita Premium Collection
Barcode (UPC) 064435205997
Net contents 4 Ounce(s)
Market status On market
Date entered into DSLD Jun 22, 2023
DSLD ID 289738
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Jiaogulan 4:1 Extract Powder by TerraVita Premium Collection, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.25 Teaspoon(s)
Maximum serving Sizes:
0.25 Teaspoon(s)
Servings per container
113
UPC/BARCODE
064435205997
IngredientAmount% DV
Jiaogulan Extract, Powder1000 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

A Dietary Supplement

Brand IP Statement(s)

Copyright 2017 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Suggested/Recommended/Usage/Directions

Directions Stir 1/4 of a teaspoon into a glass of water and consume 3 times daily, with meals.

General Statements

TerraVita is an exclusive line of premium natural products that use the finest, purest and most potent ingredients in the world. TerraVita's hallmarks are the highest possible standards of purity, potency, stability and freshness. All products are prepared with the greatest quality control, from raw materials through the entire manufacturing process, right up to the moment your product is sealed for freshness and shipped to you.

Please recycle!

FDA Disclaimer Statement

Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Jiaogulan 4:1 Extract Powder by TerraVita Premium Collection label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Jiaogulan 4:1 Extract Powder label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Jiaogulan 4:1 Extract Powder by TerraVita Premium Collection

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.25 Teaspoon(s) Dosage formPowder Servings per container113 Amounts shown are per serving.

Jiaogulan Extract, Powder

Interacts with
327 drugs
1000 mg per serving

Jiaogulan is a climbing vine used in traditional Chinese medicine as an adaptogen and for heart, blood sugar, and cholesterol support. Early human and...

Jiaogulan Extract, Powder monograph & interactions
Interaction report

Jiaogulan 4:1 Extract Powder by TerraVita Premium Collection Drug Interactions

Want to check YOUR meds against Jiaogulan 4:1 Extract Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
327Drugs
327 Moderate

Ingredients driving the most interactions

Jiaogulan Extract, Powder 327

Individual Drug Interactions

The ingredients in Jiaogulan 4:1 Extract Powder interact with 327 drugs. Click any drug to see the details.

1 of the 1 ingredient in Jiaogulan 4:1 Extract Powder interact with drugs. Each result below shows which ingredient is responsible. Jiaogulan Extract, Powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Jiaogulan 4:1 Extract Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Jiaogulan Extract, Powder3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, jiaogulan might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research suggests that jiaogulan has antiplatelet effects.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, jiaogulan might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Clinical research shows that jiaogulan can lower blood glucose levels.

Likelihood Possible Evidence B
Immunosuppressants

Theoretically, jiaogulan might decrease the effectiveness of immunosuppressive therapy.
Clinical and animal studies suggest that jiaogulan can stimulate the immune system.

Likelihood Possible Evidence D
Jiaogulan Extract, Powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Jiaogulan 4:1 Extract Powder, from the product label.

TerraVita Premium Collection

See all TerraVita Premium Collection products
Name
TerraVita Fine Whole Herbs
City
Brampton
State
Ontario
Pharmacist Counseling Corner

Jiaogulan 4:1 Extract Powder by TerraVita Premium Collection: Common Questions

Does Jiaogulan 4:1 Extract Powder by TerraVita Premium Collection interact with any medications?
Yes. Based on its ingredients, Jiaogulan 4:1 Extract Powder has a known interaction with 327 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Jiaogulan 4:1 Extract Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is jiaogulan, and what is it used for?
Jiaogulan is a plant used in traditional herbal medicine. Clinical research shows it's possibly effective for helping to lower blood sugar in diabetes. For other uses like athletic performance, cancer, heart disease, fatty liver disease, and respiratory infections, we don't yet have reliable evidence to say whether it works.
What are the most common side effects?
Diarrhea and nausea are the most common reported side effects. Some people also experience dry mouth, dizziness, or insomnia. Studies show jiaogulan has been well tolerated when taken for up to 4 months.
Can I take this if I'm pregnant or breastfeeding?
No. Jiaogulan is possibly unsafe in pregnancy because safety hasn't been established and it may affect the developing baby. Avoid it while breastfeeding too, as there isn't enough safety information. Talk with your doctor or pharmacist about alternatives if you're pregnant or nursing.
Why do I need to check this with my medications?
Jiaogulan can thin the blood, lower blood sugar, and stimulate the immune system. If you take blood thinners, diabetes drugs, or immune-suppressing medications, combining them with jiaogulan could cause problems — either too much bleeding, dangerously low blood sugar, or reduced effectiveness of your immune medication.
How long is it safe to take this?
Studies show jiaogulan is well tolerated for up to 4 months. Long-term safety beyond that period hasn't been well studied, so it's a good idea to discuss your timeline with your doctor or pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Jiaogulan 4:1 Extract Powder label
Go deeper

The Full Monographs Behind Jiaogulan 4:1 Extract Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Jiaogulan

Interacts with 327 drugs

Jiaogulan is a climbing vine used in traditional Chinese medicine as an adaptogen and for heart, blood sugar, and cholesterol support. Early human and animal studies are promising for some u...

Read the full Jiaogulan monograph →
Sources

Sources & How We Checked

Jiaogulan 4:1 Extract Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Jiaogulan 8 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Tan H, Liu ZL, Liu MJ. [Antithrombotic effect of Gynostemma pentaphyllum]. Zhingguo Zhong Xi Yi Jie He Za Zhi 1993;13:278-80.
  3. Chan LY, Chiu PY, Lau TK. An in-vitro study of ginsenoside Rb(1)-induced teratogenicity using a whole rat embryo culture model. Hum Reprod 2003;18:2166-8..
  4. Huyen VT, Phan DV, Thang P, Hoa NK, Ostenson CG. Gynostemma pentaphyllum Tea Improves Insulin Sensitivity in Type 2 Diabetic Patients. J Nutr Metab. 2013;2013:765383. doi: 10.1155/2013/765383.
  5. Li Y, Lin W, Huang J, Xie Y, Ma W. Anti-cancer effects of Gynostemma pentaphyllum (Thunb.) Makino (Jiaogulan). Chin Med. 2016 Sep 27;11:43. Review. PubMed
  6. Huyen VT, Phan DV, Thang P, Ky PT, Hoa NK, Ostenson CG. Antidiabetic effect of add-on Gynostemma pentaphyllum extract therapy with sulfonylureas in type 2 diabetic patients. Evid Based Complement Alternat Med 2012; 452313.
  7. Huyen VT, Phan DV, Thang P, Hoa NK, Ostenson CG. Antidiabetic effect of Gynostemma pentaphyllum tea in randomly assigned type 2 diabetic patients. Horm Metab Res. 2010;42(5):353-7.
  8. Rao A, Clayton P, Briskey D. The effect of an orally-dosed Gynostemma pentaphyllum extract (ActivAMP®) on body composition in overweight, adult men and women: a double-blind, randomised, placebo-controlled study. J Hum Nutr Diet 2021.

See these in context on the Jiaogulan monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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