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Dietary supplement

Just Pure Apple Cider Vinegar 1300 mg Extra Strength Ingredients & Drug Interactions

by Angry Supplements

Just Pure Apple Cider Vinegar 1300 mg Extra Strength label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Just Pure Apple Cider Vinegar 1300 mg Extra Strength against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Just Pure Apple Cider Vinegar 1300 mg Extra Strength is a dietary supplement by Angry Supplements with 1 active ingredient. Its ingredients are commonly taken for blood sugar support, weight management, digestive upset.Based on those ingredients, 162 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Apple Cider Vinegar. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Just Pure Apple Cider Vinegar 1300 mg Extra Strength by Angry Supplements

Ask about any prescription or over-the-counter medication and we check it for interactions with Just Pure Apple Cider Vinegar 1300 mg Extra Strength by Angry Supplements — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Just Pure Apple Cider Vinegar 1300 mg Extra Strength by Angry Supplements

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: apple cider vinegar at 1300 mg per capsule. The capsules also include inactive ingredients—gelatin, microcrystalline cellulose, magnesium stearate, and silicon dioxide—which are fillers and binders that help form and hold the capsule together.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Apple Cider Vinegar product and its label doesn't state a use — see Apple Cider Vinegar's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold does not establish that apple cider vinegar is effective for the purposes listed on this product—acne, athletic performance, cognitive function, dental plaque, depression, or atopic dermatitis (eczema). All of these have insufficient reliable evidence in our data to rate its usefulness.

The evidence, ingredient by ingredient Apple Cider Vinegar

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

In food amounts, apple cider vinegar is generally well tolerated. When used orally as a supplement in the short term, it also appears well tolerated.

However, the safety data for large supplement doses or long-term use is limited, and the facts note that undiluted or large medicinal doses can cause harm. Serious side effects are rare but have been reported with long-term high-dose use: low potassium, elevated renin levels, and osteoporosis (weakened bones).

One documented case involved someone who drank 250 mL (about 8 ounces) daily for 6 years and developed all three. The product facts do not provide safety information specifically for pregnancy or breastfeeding, so you'd want to discuss this with your doctor or pharmacist if you're pregnant, nursing, or planning to be.

Side effects, ingredient by ingredient Apple Cider Vinegar

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Apple Cider Vinegar.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; heart-rhythm medications.
  • For scale: 162 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your own doctor or pharmacist if you take digoxin (Lanoxin), diuretic drugs, insulin, or other antidiabetes medications. Apple cider vinegar can lower potassium and affect blood sugar, which may change how these drugs work or raise the risk of side effects.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This single-ingredient supplement is best for people without heart conditions or blood sugar disorders, and who aren't taking water pills, insulin, other diabetes drugs, or digoxin. Even so, if you take any prescription medications, talk to your doctor or pharmacist before starting it—the interactions are real enough to warrant a quick check of your exact list.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Just Pure Apple Cider Vinegar 1300 mg Extra Strength, straight from the product label.

Brand Angry Supplements
Barcode (UPC) 850003409412
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Sep 25, 2023
DSLD ID 294599
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Just Pure Apple Cider Vinegar 1300 mg Extra Strength by Angry Supplements, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
850003409412
IngredientAmount% DV
Apple Cider Vinegar1300 mg--

Other ingredients: Gelatin, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Keep out of the reach of children.

Do not use if safety seal is damaged or missing.

Caution: Do not exceed recommended dose.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Storage

Store in a cool, dry place.

Suggested/Recommended/Usage/Directions

Suggested use: Adults take two (2) capsules once daily, preferably with a well-balanced meal and water or as directed by a healthcare professional.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

GMP Good Manufacturing Practice Made in the USA With Globally Sourced Ingredients

Formulation

Zero artificial chemicals or preservatives

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Just Pure Apple Cider Vinegar 1300 mg Extra Strength by Angry Supplements label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Just Pure Apple Cider Vinegar 1300 mg Extra Strength label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Just Pure Apple Cider Vinegar 1300 mg Extra Strength by Angry Supplements

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Apple Cider Vinegar

Interacts with
162 drugs
1300 mg per serving

Apple cider vinegar is a fermented apple product that many people use hoping to help with blood sugar, weight, or digestion. The evidence for most of...

Apple Cider Vinegar monograph & interactions

Other (inactive) ingredients: Gelatin, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Just Pure Apple Cider Vinegar 1300 mg Extra Strength by Angry Supplements Drug Interactions

Want to check YOUR meds against Just Pure Apple Cider Vinegar 1300 mg Extra Strength?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
162Drugs
89 Moderate 73 Minor

Ingredients driving the most interactions

Apple Cider Vinegar 162

Individual Drug Interactions

The ingredients in Just Pure Apple Cider Vinegar 1300 mg Extra Strength interact with 162 drugs. Click any drug to see the details.

1 of the 1 ingredient in Just Pure Apple Cider Vinegar 1300 mg Extra Strength interact with drugs. Each result below shows which ingredient is responsible. Apple Cider Vinegar

Each ingredient & the kinds of drugs it affects

For each ingredient in Just Pure Apple Cider Vinegar 1300 mg Extra Strength with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Apple Cider Vinegar4 drug types · 162 drugs

Digoxin (Lanoxin)

Theoretically, concomitant use of apple cider vinegar with digoxin might increase the risk of cardiac toxicity.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. Theoretically, overuse of apple cider vinegar could decrease potassium levels, increasing the risk of toxicity with digoxin.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, concomitant use of apple cider vinegar with diuretic drugs might increase the risk of hypokalemia.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. There is some concern that people taking apple cider vinegar along with potassium depleting diuretics might have an increased risk for hypokalemia.

Likelihood Possible Evidence D
Insulin

Theoretically, concomitant use of apple cider vinegar with insulin might increase the risk of hypokalemia.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. Theoretically, overuse of apple cider vinegar concomitantly with insulin might increase the risk of hypokalemia.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking apple cider vinegar with antidiabetes drugs might increase the risk of hypoglycemia.
Apple cider vinegar might reduce fasting and postprandial blood glucose levels and decrease gastric emptying in people with diabetes. However, not all research agrees. Theoretically, it might have additive effects on glucose levels when used with antidiabetes drugs.

Likelihood Possible Evidence B
Apple Cider Vinegar full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Just Pure Apple Cider Vinegar 1300 mg Extra Strength, from the product label.

Angry Supplements

See all Angry Supplements products
Name
Angry Supplements, LLC
Street Address
1412 SW 13th Court
City
Pompano Beach
State
FL
ZipCode
33069
Phone Number
754-220-6835
Web Address
Angrysupplements.com
Pharmacist Counseling Corner

Just Pure Apple Cider Vinegar 1300 mg Extra Strength by Angry Supplements: Common Questions

Does Just Pure Apple Cider Vinegar 1300 mg Extra Strength by Angry Supplements interact with any medications?
Yes. Based on its ingredients, Just Pure Apple Cider Vinegar 1300 mg Extra Strength has a known interaction with 162 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Just Pure Apple Cider Vinegar 1300 mg Extra Strength contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does apple cider vinegar work for acne, eczema, or other skin issues?
The evidence we hold is insufficient to say whether it works for acne, eczema, or dental plaque. We can't rate it one way or the other based on the data available.
What are the side effects of apple cider vinegar supplements?
At food amounts, it's well tolerated. At larger supplement doses, especially over the long term, side effects can include low potassium (which causes weakness and heart problems), elevated renin, and weakened bones. One person who took a large amount daily for 6 years developed all three. Topically (on skin), it can cause chemical burns and irritation.
Is it safe to take during pregnancy or while breastfeeding?
The product facts don't provide safety information for pregnancy or breastfeeding. You'll want to talk with your doctor or pharmacist about whether this is right for you if you're pregnant, nursing, or planning to be.
Can I take this if I'm on a water pill or a heart medication?
Not without checking first. Apple cider vinegar can lower potassium levels, and that's especially risky if you take diuretics or digoxin—low potassium can cause serious heart problems. Talk to your doctor or pharmacist before starting.
What if I'm diabetic or take insulin?
Apple cider vinegar may lower blood sugar on its own, so it could add to the effect of insulin or antidiabetes drugs and raise your risk of low blood sugar. Check with your doctor or pharmacist first, especially if your diabetes is closely controlled.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Just Pure Apple Cider Vinegar 1300 mg Extra Strength is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Just Pure Apple Cider Vinegar 1300 mg Extra Strength label
Go deeper

The Full Monographs Behind Just Pure Apple Cider Vinegar 1300 mg Extra Strength’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Apple Cider Vinegar

Interacts with 162 drugs

Apple cider vinegar is a fermented apple product that many people use hoping to help with blood sugar, weight, or digestion. The evidence for most of these uses is limited and mixed, and the...

Read the full Apple Cider Vinegar monograph →
Sources

Sources & How We Checked

Just Pure Apple Cider Vinegar 1300 mg Extra Strength's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Apple Cider Vinegar 11 references
  1. Lhotta K, Hofle G, Gasser R, Finkenstedt G. Hypokalemia, hyperreninemia, and osteoporosis in a patient ingesting large amounts of cider vinegar. Nephron 1998;80:242-3. PubMed
  2. Hill LL, Woodruff LH, Foote JC, Barreto-Alcoba M. Esophageal injury by apple cider vinegar tablets and subsequent evaluation of products. J Am Diet Assoc 2005;105:1141-4. PubMed
  3. Hlebowicz J, Darwiche G, Björgell O, Almér LO. Effect of apple cider vinegar on delayed gastric emptying in patients with type 1 diabetes mellitus: a pilot study. BMC Gastroenterol 2007;7:46. PubMed
  4. Johnston CS, Kim CM, Buller AJ. Vinegar improves insulin sensitivity to a high-carbohydrate meal in subjects with insulin resistance or type 2 diabetes. Diabetes Care 2004;27:281-2. PubMed
  5. Lhotta, K., Hofle, G., Gasser, R., and Finkenstedt, G. Hypokalemia, hyperreninemia and osteoporosis in a patient ingesting large amounts of cider vinegar. Nephron 1998;80(2):242-243. PubMed
  6. Bunick CG, Lott JP, Warren CB, et al. Chemical burn from topical apple cider vinegar. J Am Acad Dermatol 2012;67(4):e143-4. PubMed
  7. Feldstein S, Afshar M, Krakowski AC. Chemical Burn from Vinegar Following an Internet-based Protocol for Self-removal of Nevi. J Clin Aesthet Dermatol. 2015 Jun;8(6):50.
  8. Luu LA, Flowers RH, Kellams AL, et al. Apple cider vinegar soaks [0.5%] as a treatment for atopic dermatitis do not improve skin barrier integrity. Pediatr Dermatol. 2019;36(5):634-639. PubMed
  9. Hadi A, Pourmasoumi M, Najafgholizadeh A, Clark CCT, Esmaillzadeh A. The effect of apple cider vinegar on lipid profiles and glycemic parameters: a systematic review and meta-analysis of randomized clinical trials. BMC Complement Med Ther 2021;21(1):179. PubMed
  10. Feise NK, Johnston CS. Commercial vinegar tablets do not display the same physiological benefits for managing postprandial glucose concentrations as liquid vinegar. J Nutr Metab 2020;2020:9098739. PubMed
  11. Gheflati A, Bashiri R, Ghadiri-Anari A, Reza JZ, Kord MT, Nadjarzadeh A. The effect of apple vinegar consumption on glycemic indices, blood pressure, oxidative stress, and homocysteine in patients with type 2 diabetes and dyslipidemia: A randomized contro

See these in context on the Apple Cider Vinegar monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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