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Dietary supplement

Kefir Nutrient Ingredients & Drug Interactions

by Kefiran

Kefir Nutrient label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Kefir Nutrient against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Kefir Nutrient is a dietary supplement by Kefiran with 2 active ingredients. Its ingredients are commonly taken for digestive health and balance, diarrhea (including antibiotic-related), vaginal yeast and bacterial infections.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Probiotic Cultures Blend. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Kefir Nutrient by Kefiran

Ask about any prescription or over-the-counter medication and we check it for interactions with Kefir Nutrient by Kefiran — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Kefir Nutrient by Kefiran

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 8 active ingredients.
  • “Probiotic Cultures Blend” is a proprietary blend — the label doesn't break down how much of each component you get.

Kefiran Kefir Nutrient contains 8 active ingredients, all probiotics (live beneficial bacteria) and supporting compounds. The main strains are two versions of Lactobacillus helveticus (R0052 and Lafti L10), plus Lactobacillus rhamnosus, plantarum, casei, and paracasei — each a different beneficial species traditionally found in kefir ferments.

The product also includes Kefiran, a compound derived from kefir cultures. These inactive ingredients round out the capsule: microcrystalline cellulose and a vegetable capsule shell.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Lactobacillus Helveticus's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: intestinal health and general well-being.
  • We looked for evidence on: Antibiotic-associated diarrhea, Clostridioides difficile infection, Constipation, Inflammatory bowel disease (IBD), Irritable bowel syndrome (IBS), Lactose intolerance — and 4 related terms.
  • The closest evidence on file: Lactobacillus Helveticus is rated "Insufficient Reliable Evidence To Rate" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Lactobacillus Helveticus is rated "Insufficient Reliable Evidence To Rate" for Rotaviral diarrhea, Irritable bowel syndrome (IBS).

The evidence for Lactobacillus helveticus is thin. The data we hold rates it "insufficient reliable evidence" for allergic rhinitis (hay fever), antibiotic-related diarrhea, cognitive function, depression, rotaviral diarrhea, and exercise-related respiratory infections.

In plain terms: we don't have solid proof that this strain reliably works for any of these conditions. The other probiotic strains in this product have no effectiveness ratings on file.

The evidence, ingredient by ingredient Lactobacillus Acidophilus Lactobacillus Helveticus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactobacillus helveticus is generally well tolerated in healthy people, but if you're seriously ill or immunocompromised, use it only under your doctor's guidance. The safety data overall is limited, so check with your doctor before starting.

Because these are live organisms, there's a theoretical risk they could cause infection in vulnerable patients — cases of bacterial infection have been rare but reported with some Lactobacillus species. For the other ingredients, we don't hold enough safety information to comment.

Side effects, ingredient by ingredient Lactobacillus Acidophilus Lactobacillus Helveticus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lactobacillus Helveticus.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this product if you're on antibiotic drugs. The live bacteria in Lactobacillus helveticus may be killed by antibiotics, reducing the supplement's effectiveness.

Spacing doses several hours apart is typically recommended, but your healthcare provider should confirm what works for your specific antibiotic and situation.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Kefiran Kefir Nutrient is a multi-strain probiotic supplement with limited evidence for specific health claims and a Moderate interaction with antibiotics. It's generally well tolerated in healthy people, but if you're seriously ill, immunocompromised, or taking antibiotics, talk with your doctor or pharmacist before starting it.

They can help you weigh the potential benefit against any risk and advise on timing if antibiotics are necessary.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 20, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Kefir Nutrient, straight from the product label.

Brand Kefiran
Barcode (UPC) 002110400015
Net contents 60 Veggie Capsule(s)
Market status On market
Date entered into DSLD Nov 20, 2017
DSLD ID 79512
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Kefir Nutrient by Kefiran, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
002110400015
IngredientAmount% DV
Lactobacillus Helveticus R00520 NP--
Lactobacillus rhamnosus R00110 NP--
Lactobacillus plantarum R10120 NP--
Lactobacillus casei R02150 NP--
Kefiran20 mg--
Probiotic Cultures Blend0 NP--
Lactobacillus helveticus Lafti L100 NP--
Lactobacillus rhamnosus R03430 NP--
Lactobacillus paracasei R04220 NP--

Other ingredients: Microcrystalline Cellulose, Vegetable Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Kefir is a fermented milk beverage originating from one of the world's top longevity regions.

Add Kefiran to your daily diet and enjoy the benefits of the traditional fermented beverage for intestinal health and well-being.

Manufactured in a GMP facility.

The best of kefir in a veggie capsule

Formula

During fermentation, the L. Kefiranofaciens bacteria in traditional kefir produces kefiran, a polysaccharide that - along with the probiotic cultures - is believed to be the primary source of kefir's health benefits.

Two Kefiran capsules provide the same amount of Kefiran found in 1 quart of traditional Kefir plus 50 billion CFU (colony forming units) of active cultures.

+50 Billion active probiotic cultures per serving

Kefiran polysaccharide from fermented non-GMO rice

Formulation

Unlike traditional kefir, Kefiran contains no dairy, lactose or gluten.

Kefiran is vegan and low calorie.

No Dairy No Gluten No Lactose

Vegan

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: For best results, take two capsules daily with a light meal.

Storage

Store in a dry place at 72(0) F or below.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Kefir Nutrient by Kefiran label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Kefir Nutrient label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Kefir Nutrient by Kefiran

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Kefiran

20 mg per serving Form: Rice

Probiotic Cultures Blend

Interacts with
182 drugs
0 NP per serving

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy p...

Probiotic Cultures Blend monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Vegetable Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Kefir Nutrient by Kefiran Drug Interactions

Want to check YOUR meds against Kefir Nutrient?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Probiotic Cultures Blend 182

Individual Drug Interactions

The ingredients in Kefir Nutrient interact with 182 drugs. Click any drug to see the details.

1 of the 2 ingredients in Kefir Nutrient interact with drugs. Each result below shows which ingredient is responsible. Probiotic Cultures Blend

Each ingredient & the kinds of drugs it affects

For each ingredient in Kefir Nutrient with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Probiotic Cultures Blend1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Probiotic Cultures Blend full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Kefir Nutrient, from the product label.

Kefiran

See all Kefiran products
Name
LaneLabs-USA, Inc
City
Vero Beach
State
FL
ZipCode
32963
Phone Number
1-800-526-3005
Web Address
www.kefiranhealth.com
Pharmacist Counseling Corner

Kefir Nutrient by Kefiran: Common Questions

Does Kefir Nutrient by Kefiran interact with any medications?
Yes. Based on its ingredients, Kefir Nutrient has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Kefir Nutrient contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Kefiran Kefir Nutrient if I'm on antibiotics?
You should talk with your doctor or pharmacist first. Antibiotics can kill the live bacteria in this supplement, which may make it less effective. They'll likely recommend spacing your doses apart, but the exact timing depends on which antibiotic you're taking.
Will Kefiran Kefir Nutrient help with my diarrhea or digestive issues?
The evidence we hold doesn't establish that Lactobacillus helveticus reliably works for diarrhea or other digestive concerns. Other ingredients in this product haven't been rated for effectiveness. Talk with your doctor about whether a probiotic might help your specific situation.
Is this supplement safe if I have a weakened immune system?
The data advises caution. Because these are live organisms, people who are seriously ill or immunocompromised should use this product only under their doctor's guidance. Your doctor can weigh whether the potential benefit outweighs any risk for you personally.
What exactly is Kefiran?
Kefiran is a compound derived from kefir cultures — the fermented milk drink. In this supplement, it's one of several active ingredients, though we don't have specific effectiveness ratings for it on its own.
Does this product contain any fillers?
Yes, the capsule contains microcrystalline cellulose (an inactive binder) and a vegetable capsule shell. The rest of the contents are the active probiotic strains and Kefiran.
Are there any side effects I should know about?
Lactobacillus helveticus is generally well tolerated in healthy people. However, because these are live organisms, there's a theoretical risk of infection in rare cases, particularly in people who are very ill or have a weakened immune system. If you experience unusual symptoms after starting, talk with your doctor.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Kefir Nutrient is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Kefir Nutrient label
Go deeper

The Full Monographs Behind Kefir Nutrient’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph → Herb & supplement monograph

Lactobacillus Helveticus

Interacts with 182 drugs

Lactobacillus helveticus is a lactic acid bacterium used as a probiotic, often combined with other strains in mood, gut, and general wellness products. Early research is interesting—especial...

Read the full Lactobacillus Helveticus monograph →
Sources

Sources & How We Checked

Kefir Nutrient's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 17 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Helveticus 2 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed

See these in context on the Lactobacillus Helveticus monograph →

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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