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Dietary supplement

L-Carnosine 1000 mg Ingredients & Drug Interactions

by Jarrow Formulas

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

L-Carnosine 1000 mg is a dietary supplement by Jarrow Formulas with 1 active ingredient. Its ingredients are commonly taken for anti-aging and general wellness, exercise performance and muscle support, brain and cognitive health.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Carnosine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of L-Carnosine 1000 mg by Jarrow Formulas

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

L-Carnosine 1000 mg is a single-ingredient supplement. Carnosine is a small protein-like compound (dipeptide) found naturally in muscles and the brain.

The product also contains inactive ingredients — microcrystalline cellulose, hydroxypropylmethylcellulose, water, magnesium stearate, and silicon dioxide — which serve as capsule filler and binder.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: mitochondrial health and antioxidant support.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence for carnosine is mixed and limited. It's rated possibly ineffective for autism spectrum disorder.

For age-related cognitive decline, Alzheimer's disease, athletic performance, cataracts, and general cognitive impairment, there isn't enough reliable evidence yet to say whether it works. The data we hold doesn't establish that it's effective for these conditions.

The evidence, ingredient by ingredient Carnosine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Carnosine is generally well tolerated in short-term studies, but we don't have much long-term safety data. In trials, some people reported decreased appetite, dry mouth, small weight changes, foot and joint pain, and in rare cases, pneumonia — though these are uncommon.

There isn't enough safety information to use L-Carnosine during pregnancy or while breastfeeding. Talk with your doctor or pharmacist if you're pregnant, planning to become pregnant, or nursing before taking this supplement.

Side effects, ingredient by ingredient Carnosine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Carnosine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any medication to control blood sugar or manage diabetes — insulin, metformin, sulfonylureas, GLP-1 agonists, or other antidiabetes drugs — double-check with your doctor or pharmacist before adding L-Carnosine. The supplement may increase the risk of low blood sugar when combined with these medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

L-Carnosine might be worth considering if you're curious about muscle or brain health and don't take diabetes medications. If you take any blood-sugar-lowering drug, check with your doctor or pharmacist first — carnosine could lower your glucose further.

Since long-term safety data are thin, discuss this supplement with your healthcare provider before starting, especially if you plan to use it regularly.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Carnosine 1000 mg, straight from the product label.

Brand Jarrow Formulas
Barcode (UPC) 790011150527
Net contents 90 Veggie Capsule(s)
Market status On market
Date entered into DSLD Jan 24, 2024
DSLD ID 307637
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), No Allergies, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Carnosine 1000 mg by Jarrow Formulas, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
45
UPC/BARCODE
790011150527
IngredientAmount% DV
L-Carnosine1000 mg--

Other ingredients: Microcrystalline Cellulose, Hydroxypropylmethylcellulose, Water, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: Adults take 2 capsules once a day with juice or water on an empty stomach or as directed by your qualified healthcare professional.

Formula

L-Carnosine is a dipeptide antioxidant found in the brain, heart, skin, muscles, kidneys and stomach that supports mitochondrial health.

Precautions

Warning: Consult a healthcare professional before using this product if you are pregnant, nursing, under the age of 18, are taking medication or have a medical condition; if adverse reactions occur, discontinue use.

Warning: Consult a healthcare professional before using this product if you are pregnant, nursing, under the age of 18, are taking medication or have a medical condition; if adverse reactions occur, discontinue use.

Keep out of the reach of children.

Do not use if safety seal is damaged or missing.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Vegan

Dipeptide antioxidant Supports mitochondrial health

Non-GMO Gluten-free

No wheat, gluten, soybeans, dairy, egg, fish/shellfish, peanuts/tree nuts or sesame. IGEN Non-GMO tested

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

IGEN Non-GMO tested

Brand IP Statement(s)

Copyright 2022 Jarrow Formulas

General Statements

Energy

See for yourself

L-Carnosine 1000 mg by Jarrow Formulas label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in L-Carnosine 1000 mg by Jarrow Formulas

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container45 Amounts shown are per serving.

L-Carnosine

Interacts with
86 drugs
1000 mg per serving Form: Beta-Alanyl-L-Histidine

Carnosine is a naturally occurring dipeptide (made of beta-alanine and histidine) that acts as an antioxidant and buffer in muscle and brain. It is so...

L-Carnosine monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Hydroxypropylmethylcellulose, Water, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

L-Carnosine 1000 mg by Jarrow Formulas Drug Interactions

Want to check YOUR meds against L-Carnosine 1000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in L-Carnosine 1000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Carnosine1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking carnosine with antidiabetes drugs might increase the risk of hypoglycemia.
Some, but not all, preliminary clinical research shows that carnosine might reduce fasting blood glucose levels.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for L-Carnosine 1000 mg, from the product label.

Jarrow Formulas

See all Jarrow Formulas products
Name
Jarrow Formulas, Inc.
City
Sherman Oaks
State
CA
ZipCode
91403
Phone Number
1-866-459-4154
Web Address
www.Jarrow.com
Pharmacist Counseling Corner

L-Carnosine 1000 mg by Jarrow Formulas: Common Questions

Does L-Carnosine 1000 mg by Jarrow Formulas interact with any medications?
Yes. Based on its ingredients, L-Carnosine 1000 mg has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
L-Carnosine 1000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take L-Carnosine if I have diabetes?
Only with your doctor's or pharmacist's approval. Carnosine may lower blood glucose, so combined with your diabetes medication, it could increase the risk of low blood sugar (hypoglycemia). Your healthcare provider can advise whether it's safe for you and adjust your medication if needed.
What side effects might I notice?
Most people tolerate it well, but some report decreased appetite, dry mouth, small weight changes, foot or joint pain, or rarely, pneumonia. These are uncommon. If you notice anything unusual, stop taking it and tell your doctor.
Is L-Carnosine safe to take long-term?
Short-term use appears well tolerated, but we don't have enough long-term safety data to say for certain. If you're thinking about using it regularly, talk with your doctor or pharmacist about the pros and cons for your situation.
Will L-Carnosine help my memory or prevent Alzheimer's?
Right now, there isn't enough reliable evidence to say whether carnosine helps with age-related cognitive decline or Alzheimer's. The research is still preliminary.
Can I take this while pregnant or breastfeeding?
No — there isn't enough safety information. Avoid use during pregnancy and while breastfeeding. If you're expecting or nursing and interested in supplements, talk with your doctor or pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if L-Carnosine 1000 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Carnosine 1000 mg label
Go deeper

The Full Monographs Behind L-Carnosine 1000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

L-Carnosine 1000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Carnosine 5 references
  1. Chengappa KN, Turkin SR, DeSanti S, et al. A preliminary, randomized, double-blind, placebo-controlled trial of L-carnosine to improve cognition in schizophrenia. Schizophr Res 2012;142(1-3):145-52. PubMed
  2. Karkabounas S, Papadopoulos N, Anastasiadou C, et al. Effects of a-lipoic Acid, carnosine, and thiamine supplementation in obese patients with type 2 diabetes mellitus: A randomized, double-blind study. J Med Food. 2018;21(12):1197-1203.
  3. Peng W, Mao P, Liu L, et al. Effect of carnosine supplementation on lipid profile, fasting blood glucose, HbA1C and insulin resistance: a systematic review and meta-analysis of long-term randomized controlled trials. Complement Ther Med 2020;48:102241. PubMed
  4. Siriwattanasit N, Satirapoj B, Supasyndh O. Effect of oral carnosine supplementation on urinary TGF-ß in diabetic nephropathy: a randomized controlled trial. BMC Nephrol 2021;22(1):236. PubMed
  5. Sureshkumar K, Durairaj M, Srinivasan K, et al. Effect of L-Carnosine in Patients with Age-Related Diseases: A Systematic Review and Meta-Analysis. Front Biosci (Landmark Ed) 2023;28(1):18. PubMed

See these in context on the Carnosine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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