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Dietary supplement

L-Carnosine 500 mg Unflavored Ingredients & Drug Interactions

by Nutricost

L-Carnosine 500 mg Unflavored label
See full label image
Powder Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking L-Carnosine 500 mg Unflavored against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

L-Carnosine 500 mg Unflavored is a dietary supplement by Nutricost with 1 active ingredient. Its ingredients are commonly taken for anti-aging and general wellness, exercise performance and muscle support, brain and cognitive health.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Carnosine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against L-Carnosine 500 mg Unflavored by Nutricost

Ask about any prescription or over-the-counter medication and we check it for interactions with L-Carnosine 500 mg Unflavored by Nutricost — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of L-Carnosine 500 mg Unflavored by Nutricost

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Oct 1, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-carnosine, a compound made up of two amino acids that your body can also make on its own. L-carnosine is naturally found in muscle and brain tissue.

There are no inactive ingredients listed for this unflavored powder.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Carnosine product and its label doesn't state a use — see Carnosine's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for L-carnosine is mixed and limited. For autism spectrum disorder, it's rated possibly ineffective.

For age-related cognitive decline, Alzheimer disease, athletic performance, cataracts, and general cognitive impairment, the evidence isn't established well enough in the data we hold to rate it one way or another. If you're considering it for any of these purposes, talk with your doctor or pharmacist about what the current research actually shows.

The evidence, ingredient by ingredient Carnosine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-carnosine is generally well tolerated in short-term studies, but long-term safety data are limited, so we don't yet know what happens with extended use. Some people have reported decreased appetite, dry mouth, small weight changes, foot and joint pain, and rarely, pneumonia.

The safety data advises against use during pregnancy and while breastfeeding because there isn't enough information to know whether it's safe in those situations.

Side effects, ingredient by ingredient Carnosine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Carnosine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any antidiabetes medication—insulin, metformin, sulfonylureas, or any other type—check your exact drugs with the search tool on this page before taking L-carnosine. The risk is moderate: carnosine may lower blood sugar, and combining it with these drugs could increase the chance of low blood sugar.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

L-carnosine may be an option if you're interested in its potential cognitive or athletic effects, but the evidence for most of those uses is thin or absent. If you take an antidiabetes drug, you'll need to check with your doctor or pharmacist first because carnosine could lower blood sugar.

And because long-term safety data are limited, it's worth discussing with your healthcare provider before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 23, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Carnosine 500 mg Unflavored, straight from the product label.

Brand Nutricost
Barcode (UPC) 810014671277
Net contents 3.5 Ounce(s); 100 Gram(s)
Market status On market
Date entered into DSLD May 23, 2024
DSLD ID 311735
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Carnosine 500 mg Unflavored by Nutricost, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.5 Gram(s)
Maximum serving Sizes:
0.5 Gram(s)
Servings per container
200
UPC/BARCODE
810014671277
IngredientAmount% DV
L-Carnosine500 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, mix 1 scoop daily with 6-10 oz of water or as directed by your healthcare professional.

Formulation

Third party tested

Gluten-free

Made and quality tested in the USA with globally sourced ingredients.

Non-GMO product

Precautions

Warning: For healthy individuals 18 years and older.

Consult a healthcare professional prior to use if you are pregnant or nursing, taking medication, or have a medical condition.

Keep out of reach of children.

Do not use if safety seal is broken or missing.

Storage

Notice: Store in a cool, dry place. Contents are sold by weight, not volume. Some settling may occur.

Formula

L-Carnosine 500 mg per serving 100g per container

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

Nutricost Quality Guaranteed GMP compliant facility Third Party Tested

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

L-Carnosine 500 mg Unflavored by Nutricost label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

L-Carnosine 500 mg Unflavored label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in L-Carnosine 500 mg Unflavored by Nutricost

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.5 Gram(s) Dosage formPowder Servings per container200 Amounts shown are per serving.

L-Carnosine

Interacts with
86 drugs
500 mg per serving

Carnosine is a naturally occurring dipeptide (made of beta-alanine and histidine) that acts as an antioxidant and buffer in muscle and brain. It is so...

L-Carnosine monograph & interactions
Interaction report

L-Carnosine 500 mg Unflavored by Nutricost Drug Interactions

Want to check YOUR meds against L-Carnosine 500 mg Unflavored?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

L-Carnosine 86

Individual Drug Interactions

The ingredients in L-Carnosine 500 mg Unflavored interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in L-Carnosine 500 mg Unflavored interact with drugs. Each result below shows which ingredient is responsible. L-Carnosine

Each ingredient & the kinds of drugs it affects

For each ingredient in L-Carnosine 500 mg Unflavored with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Carnosine1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking carnosine with antidiabetes drugs might increase the risk of hypoglycemia.
Some, but not all, preliminary clinical research shows that carnosine might reduce fasting blood glucose levels.

Likelihood Possible Evidence D
L-Carnosine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for L-Carnosine 500 mg Unflavored, from the product label.

Nutricost

See all Nutricost products
Name
Nutricost
Street Address
351 E 1750 N
City
Vineyard
State
UT
ZipCode
84059
Phone Number
(866) 438-3694
Web Address
www.nutricost.com
Pharmacist Counseling Corner

L-Carnosine 500 mg Unflavored by Nutricost: Common Questions

Does L-Carnosine 500 mg Unflavored by Nutricost interact with any medications?
Yes. Based on its ingredients, L-Carnosine 500 mg Unflavored has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
L-Carnosine 500 mg Unflavored contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant or breastfeeding?
The safety data advises against it. There isn't enough information about L-carnosine in pregnancy and while breastfeeding to know whether it's safe. Talk with your doctor or pharmacist about what's right for your situation.
What side effects have been reported?
Some people have reported decreased appetite, dry mouth, small weight changes, foot and joint pain, and rarely, pneumonia. Keep in mind that long-term safety data are limited, so we don't have a complete picture of all possible effects with extended use.
Does L-carnosine actually improve brain function or athletic performance?
The evidence isn't established well enough yet. For autism, it's rated possibly ineffective. For cognitive decline, Alzheimer disease, athletic performance, cataracts, and cognitive impairment in general, the data we hold doesn't support a clear rating either way.
What is L-carnosine and where does it come from?
L-carnosine is a compound made from two amino acids. Your body makes its own carnosine naturally in muscle and brain tissue, and you can also get it from meat and fish. This supplement provides a concentrated dose of it in powder form.
I take a blood sugar medication. Is this product okay for me?
Not without checking first. Carnosine may lower blood sugar, and combined with your medication, it could increase the risk of low blood sugar. Talk with your doctor or pharmacist about your specific drug and whether it's safe to use this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if L-Carnosine 500 mg Unflavored is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Carnosine 500 mg Unflavored label
Go deeper

The Full Monographs Behind L-Carnosine 500 mg Unflavored’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Carnosine

Interacts with 86 drugs

Carnosine is a naturally occurring dipeptide (made of beta-alanine and histidine) that acts as an antioxidant and buffer in muscle and brain. It is sold as an anti-aging and performance supp...

Read the full Carnosine monograph →
Sources

Sources & How We Checked

L-Carnosine 500 mg Unflavored's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Carnosine 5 references
  1. Chengappa KN, Turkin SR, DeSanti S, et al. A preliminary, randomized, double-blind, placebo-controlled trial of L-carnosine to improve cognition in schizophrenia. Schizophr Res 2012;142(1-3):145-52. PubMed
  2. Karkabounas S, Papadopoulos N, Anastasiadou C, et al. Effects of a-lipoic Acid, carnosine, and thiamine supplementation in obese patients with type 2 diabetes mellitus: A randomized, double-blind study. J Med Food. 2018;21(12):1197-1203.
  3. Peng W, Mao P, Liu L, et al. Effect of carnosine supplementation on lipid profile, fasting blood glucose, HbA1C and insulin resistance: a systematic review and meta-analysis of long-term randomized controlled trials. Complement Ther Med 2020;48:102241. PubMed
  4. Siriwattanasit N, Satirapoj B, Supasyndh O. Effect of oral carnosine supplementation on urinary TGF-ß in diabetic nephropathy: a randomized controlled trial. BMC Nephrol 2021;22(1):236. PubMed
  5. Sureshkumar K, Durairaj M, Srinivasan K, et al. Effect of L-Carnosine in Patients with Age-Related Diseases: A Systematic Review and Meta-Analysis. Front Biosci (Landmark Ed) 2023;28(1):18. PubMed

See these in context on the Carnosine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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